Clinical trials: sponsored by Xijing Hospital
Infections
Establishment of Risk Indicators and Early Warning System in Infection Patients
Serious infections refer to life-threatening infections with a morbidity and mortality rate of up to 50%, and are the main cause of death in critically ill patients, mainly including systemic inflammatory response syndrome…
- Trial name
- NCT05099120
- Volunteers
- 16,000 people
- Sponsor
- Xijing Hospital
Epilepsy，Cognition
Clinical Study on the Effect of Improving Sleep Quality on Cognitive Function in Patients With Epilepsy
Epilepsy is one of the common chronic diseases of the central nervous system. 30% to 40% of patients with epilepsy have varying degrees of cognitive impairment, which affects their quality of life.
- Trial name
- NCT05256173
- Testing
- Melatonin Tablets, Lactasin Tablets, transcutaneous vagus nerve stimulation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xijing Hospital
Gastritis, Peptic Ulcer
Helicobacter Pylori Eradication With Probiotics Combined With Triple Therapy Versus Bismuth-containing Quadruple Therapy
This study aims at evaluating efficacy and safety of probiotics combined with triple therapy (Clostridium butyricum capsule and Bacillus coagulans tablets, esomeprazole, clarithromycin and amoxicillin) versus bismuth-containing…
- Conditions
- Gastritis, Peptic Ulcer, Dyspepsia
- Trial name
- NCT05237115
- Testing
- Clostridium butyricum capsule, esomeprazole, amoxicillin
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Ischemic Stroke
Low-dose Aspirin Therapy in Patients With Ischemic Stroke and Microbleeds
The purpose of this study is to investigate the safety and efficacy of low-dose (50mg) aspirin as a secondary prevention drug in patients with Non-Cardioembolic Ischemic Stroke accompanied by cerebral microbleeds.
- Trial name
- AIM (NCT04504864)
- Testing
- low-dose aspirin, conventional-does aspirin
- Where
- 6 sites in China
- Volunteers
- 400 people
- Sponsor
- Xijing Hospital
Vulva Lichen Sclerosus
Carbon Dioxide（CO2）Fractional Laser Plus Photodynamic Therapy in Female Patients With Vulvar Lichen Sclerosus
The objective of this study is to evaluate the safety and efficacy of CO2 fractional laser combined with photodynamic therapy in female patients with vulvar lichen sclerosus.
- Trial name
- NCT05228483
- Testing
- CO2 fractional laser, 5-aminolevulinic acid (5-ALA) with red light illumination, Mometasone furoate (MMF) 0.1% ointment
- Where
- China
- Volunteers
- 134 people
- Sponsor
- Xijing Hospital
Early Diagnosis of Colorectal Cancer and Adenoma
Correlation Between SFRP1 and Colorectal Cancer and Adenoma
In summary, our study demonstrated the methylation sites of SFRP1 gene promoter in patients with colorectal cancer and adenoma and found SFRP1_16_17_18 CpG site was good performance as a diagnostic marker of colorectal cancer.
- Trial name
- NCT05204433
- Testing
- no intervention
- Where
- China
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Pancreatic Neoplasms
Correlation Between Elastic Modulus of Ultrasonic Shear Wave and Tumor Stromal Component in Pancreatic Cancer
Pancreatic cancer is a gastrointestinal tumor with a high degree of malignancy. Currently, there are many first-line chemotherapy regimens in clinical practice, but the individual selection of chemotherapy regimens has not been…
- Trial name
- NCT05187416
- Testing
- two-dimensional shear wave elastography
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xijing Hospital
Type 2 Diabetes Mellitus
Study for Beinaglutide Versus Glargine Therapy in Glycemic Variability of Type 2 Diabetes Mellitus
The investigators aimed to assess the efficacy and safety of Beinaglutide versus glargine , in individuals with type 2 diabetes who did not achieve adequate glycaemic control with oral antidiabetic drug.
- Trial name
- NCT03829891
- Testing
- Beinaglutide, glargine
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Xijing Hospital
Stress Fracture, Vitamin d
The Effect of Vitamin D and Calcium Supplementation on the Prevention of Stress Fractures.
The main objective of this study is to find whether supplemental vitamin d and calcium can reduce the incidence of stress fractures in recruits.
- Trial name
- NCT05186194
- Testing
- Vitamin D, Calcium
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Xijing Hospital
Breast Cancer, HER2-positive Breast Cancer
RC48 for Neoadjuvant Chemotherapy of HER2 Positive Breast Cancer
This is a single-arm exploratory study to explore the effect of RC48 in HER2-positive neoadjuvant therapy and evaluate the non-inferiority of RC48 by comparing the latest reported data of T-DM1 in neoadjuvant therapy.
- Trial name
- NCT05134519
- Testing
- Recombinant humanized anti-HER2 monoclonal antibody-MMAE coupling agent (RC48-ADC)
- Volunteers
- 20 people
- Sponsor
- Xijing Hospital
Psoriasis
Dietary Perceptions and Practices in Chinese Psoriasis Patients
The influences of diet on psoriasis have been long discussed. As reported in previous publications, a majority of U.S. psoriasis population show high interest in the role of diet on their skin conditions.
- Trial name
- NCT05118425
- Where
- China
- Volunteers
- 3,453 people
- Sponsor
- Xijing Hospital
Severe Stroke, Acute Stroke
Optimizing Early Enteral Nutrition in Severe Stroke
The purpose of this academic lead study is to explore the ideal nutritional support strategy for patient with acute severe stroke.
- Conditions
- Severe Stroke, Acute Stroke, Dysphagia
- Trial name
- OPENS (NCT02982668)
- Testing
- Initial enteral feeding, metoclopramide or mosapride
- Where
- 4 sites in China
- Volunteers
- 306 people
- Sponsor
- Xijing Hospital
Vertigo
Function Evaluation of Older Patients With Vertigo and Intervention Study of New Rehabilitation Methods
By evaluating the balance, gait and cognitive functions of the elderly patients with vertigo, the relevant functional disorders of the elderly patients with vertigo were clarified, and the functional disorders of the elderly…
- Trial name
- NCT05103748
- Testing
- Traditional vestibular rehabilitation, Cognitive and vestibular dual task training
- Where
- China
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
HPV Vaccination、HPV Related Diseases、Protective Efficacy
Protective Efficacy of HPV Vaccination After Treatment of HPV Related Diseases
To understand the HPV infection status and subtype distribution of patients, and to study the protective effect of prophylactic HPV vaccination on the recurrence of HPV related diseases after treatment through a prospective…
- Trial name
- NCT05085093
- Testing
- HPV vaccine
- Where
- China
- Volunteers
- 414 people
- Sponsor
- Xijing Hospital
Attention-deficit/Hyperactivity Disorder
Gut Microbiome and Serum Metabolome Alterations in ADHD Patients
Host-microbe interactions play a key role in brain development and function and in the etiology of neurodevelopmental disorders.
- Trial name
- ADHD (NCT03447223)
- Where
- China
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Post Operative Cognitive Dysfunction
Preoperative Vitamin B12 and Folic Acid on POCD in Elderly Non-cardiac Surgical Patients
This study will recruit patients more than 65 years old eligible for non-cardiac surgery. Patients who participate will take either vitamin B12 and folic acid supplementation or placebo for 7 days before surgery.
- Trial name
- B12-POCD (NCT03485404)
- Testing
- methylcobalamin, Folic Acid, non-cardiac surgery
- Where
- 13 sites in China
- Volunteers
- 40 people
- Sponsor
- Xijing Hospital
Chronic Pelvic Pain, Chronic Prostatitis
Real World Study on the Application of Appropriate Electrophysiological Technology in the Diagnosis and Treatment of Andrology Diseases in Northwest China
To carry out real world research on the application of electrophysiology and other suitable technologies in the prevention and treatment of male diseases in medical institutions at all levels in Northwest China, and establish a…
- Trial name
- NCT04976751
- Testing
- Percutaneous electrical nerve stimulation treatment
- Where
- China
- Volunteers
- 274 people
- Sponsor
- Xijing Hospital
Asthma in Children
A Comparative Study on the Efficacy of Different Stepping-down Therapy for Childhood Asthma
This study is a 24-week, randomized, parallel group comparative effectiveness study to evaluate the risk of stepping down therapy for patients with well-controlled asthma treated with combination Inhaled corticosteroids (ICS) and…
- Trial name
- NCT04953741
- Testing
- Fluticasone propionate inhaled aerosol
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Xijing Hospital
Tricuspid Regurgitation
Safety and Feasibility of the Transcatheter Tricuspid Valve Repair System (Trialign)
The purpose of the study is to demonstrate safety and feasibility of the transcatheter tricuspid valve repair system (Trialign) for the treatment or reduction of moderate to severe functional tricuspid regurgitation.
- Trial name
- NCT04936802
- Testing
- Transcatheter tricuspid valve repair system (Trialign)
- Volunteers
- 5 people
- Sponsor
- Xijing Hospital
Vaginal Atrophy
A Clinical Clinical Observation of CO2 Fractional Laser in Female Vaginal Repair
1. Vaginal atrophy is the most common indication in the treatment of vaginal rejuvenation. Its main manifestation is vaginal relaxation syndrome, which may be the early symptom of female pelvic floor dysfunction.
- Trial name
- NCT04492176
- Testing
- CO2 fractional laser（ACUPULSE,Lumenis）
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital