Clinical trials: sponsored by Xijing Hospital
Healthy Volunteers
A Phase I Clinical Trial of Meplazumab in Healthy Volunteer
This is a single center, double-blinded, placebo-controlled phase I clinical trail in healthy volunteer of meplazumab for injection.
- Trial name
- NCT04369586
- Testing
- meplazumab for injection
- Where
- China
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Gastric Cancer, Helicobacter Pylori Infection
Helicobacter Pylori Eradication With Different Bismuth Quadruple Therapies
This study aims to compare efficacy and safety of bismuth-containing quadruple therapy（with rabeprazole amoxicillin clarithromycin）of different kinds of bismuth（Bismuth potassium citrate, pectin bismuth capsules, pectin bismuth…
- Conditions
- Gastric Cancer, Helicobacter Pylori Infection, Bismuth
- Trial name
- NCT04209933
- Testing
- Bismuth potassium citrate containing quadruple therapy, Colloidal pectin bismuth capsules containing quadruple therapy, Colloidal pectin bismuth particles A quadruple therapy
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Scalp Psoriasis
Evaluate the Efficacy and Safety of Boroda Supramolecular Active Zinc in the Treatment of Scalp Psoriasis
A multicenter, randomized, single-blind, parallel-controlled clinical study to evaluate the efficacy and safety of boroda supramolecular active zinc in the treatment of scalp psoriasis.
- Trial name
- NCT04801433
- Testing
- Boleda Supramolecular Active Zinc Conditioner, Capotetriol scalp solution, Supramolecular Hydrogel
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Xijing Hospital
Berberine Hydrochloride
Effectiveness and Safety of Berberine Hydrochloride and Bifidobacterium in People With Abnormal Glucose Level
The aim of this study is to assess the beneficial effects of Bifidobacterium and Berberine Hydrochloride on lowering glucose and delaying progress to diabetes in patients with prediabetes and to detect the potential mechanism.
- Trial name
- NCT03330184
- Testing
- Berberine Hydrochloride group, Bifidobacterium group, Berberine Hydrochloride and Bifidobacterium group
- Volunteers
- 300 people
- Sponsor
- Xijing Hospital
Primary Axillary Hyperhidrosis
Fractionated Microneedle Radiofrequency for Treatment of Primary Axillary Hyperhidrosis
Twenty patients with PAH had 1 session of Fractionated microneedle radiofrequency treatment. Clinical improvement was evaluated using a Hyperhidrosis Disease Severity Scale (HDSS) and photographs were taken using the…
- Trial name
- NCT02823340
- Testing
- Fractional microneedle RF(United, Peninsula Medical, China)
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Xijing Hospital
Telangiectasia
Clinical Observation of Pulsed Dye Laser and Intense Pulsed Light in Treating Facial Telangiectasia
1. Facial telangiectasia is one of the common skin vascular lesions characterized by dilated cutaneous vasculatures in the skin surface or mucous membranes. Lesions are generally sensitive to exposure of cold, heat and sun.
- Trial name
- NCT04795310
- Testing
- Pulsed dye laser
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Xijing Hospital
Femur Head Necrosis, Adverse Effect of Glucocorticoids and Synthetic Analogues
GWAS Identified Susceptibility Loci for Glucocorticoid-induced FHN in the Chinese Population
This is a observation clinical trial. We are collecting the patients with glucocorticoid. They were divided into the experiment group (with femur head necrosis) and control group (without femur head necrosis).Then, we will…
- Trial name
- NCT02365077
- Where
- China
- Volunteers
- 2,500 people
- Sponsor
- Xijing Hospital
Hypertrophic Obstructive Cardiomyopathy
Speckle Tracking Echocardiography Analysis of Left Ventricular Myocardium After Percutaneous Intramyocardial Septal Radiofrequency Ablation for Hypertrophic Obstructive Cardiomyopathy
Objective to investigate the left ventricular (LV) systolic function by speckle tracking echocardiography before and after percutaneous intramyocardial septal radiofrequency ablation for hypertrophic obstructive cardiomyopathy…
- Trial name
- NCT04777188
- Testing
- Percutaneous Intramyocardial Septal Radiofrequency Ablation for hypertrophic obstructive cardiomyopathy
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Xijing Hospital
Heart Failure
First in Man Study of Implantable Alginate Hydrogel
The objective of this clinical research is to evaluate the safety and effectiveness of Implantable Alginate Hydrogel to reconstruct the left ventricle in the treatment of heart failure
- Trial name
- NCT04781660
- Testing
- Implantable Alginate Hydrogel
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Xijing Hospital
VTE After Stroke
Management of TA in VaS-Patients and HT
Stroke is an independent risk factor for venous thrombosis (VTE), which leads to a significant increase in the mortality and disability rate after stroke.
- Trial name
- NCT04726007
- Testing
- Antithrombotic Agents
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Xijing Hospital
Hypertrophic Obstructive Cardiomyopathy
The Clinical Research of the Safety and Effectiveness Evaluation for Using Echocardiography-guided Liwen RF Radiofrequency Ablation System to Treat Hypertrophic Obstructive Cardiomyopathy
Objective to investigate the safety and effectiveness of Echocardiography-guided radiofrequency ablation in patients with Hypertrophic obstructive Cardiomyopathy (HOCM).
- Trial name
- NCT04355260
- Testing
- Echocardiography-guided Radiofrequency ablation for Hypertrophic obstructive Cardiomyopathy (HOCM).
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Xijing Hospital
Acute Kidney Injury
Association of Tissue Oxygen Saturation With Postoperative Acute Kidney Injury in Double Valves Replacement Surgery
To investigate the relationship of tissue oxygenation of different organs and tissue beds (e.g., a tissue bed on the arm vs. leg vs.
- Trial name
- NCT03323203
- Testing
- FORE-SIGHT Elite, CASMED, Inc., Branford, Connecticut, USA
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Xijing Hospital
Acute Kidney Injury
A Clinical Score to Predict Acute Kidney Injury After Heart Valve Replacement Surgery
Acute kidney injury (AKI) is a common and severe complication of cardiac surgery. The main stay treatment remains preventive with no clear evidence supporting any therapeutic interventions.
- Trial name
- NCT04237636
- Where
- China
- Volunteers
- 3,392 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Acute Myocardial Infarction, Myocardial Reperfusion Injury
Optimized Cardioprotection Therapy in Obese Subjects With AMI
The purpose of this study is to investigate the efficacy and mechanism of Adipokines Cardiac Protection in Obese Patients With acute myocardial infarction (AMI) Who Have Undergone Percutaneous Coronary Intervention (PCI).
- Conditions
- Acute Myocardial Infarction, Myocardial Reperfusion Injury, Obesity, Adiposis; Heart
- Trial name
- NCT04570514
- Testing
- PCI
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xijing Hospital
Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD)), Obesity
Optimized Cardioprotection Therapy in Obese Subjects With CAD
The purpose of this study is to investigate the efficacy and mechanism of Adipokines Cardiac Protection in Obese Patients With coronary artery disease (CAD).
- Conditions
- Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD)), Obesity, Adiposis; Heart
- Trial name
- NCT04570527
- Testing
- PCI
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xijing Hospital
Epilepsy
The Diagnostic Value of Autoimmune Antibody Detection in Newly Onset and Chronic Epilepsy
multi-central and prospectively study the diagnostic value of autoimmune antibody detection in new and chronic epilepsy, and provide reference for clinical practice
- Trial name
- NCT04516590
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Bile Reflux Gastritis, Gastric Cancer
Study on the Effect of Bile Reflux on Gastric Cancer and Its Precancerous Lesions: a Cross-sectional Study.
To explore the effects of bile reflux on gastric cancer and its precancerous lesions, so as to better prevent the occurrence and development of gastric cancer.
- Conditions
- Bile Reflux Gastritis, Gastric Cancer, Helicobacter Pylori Infection, Intestinal Metaplasia
- Trial name
- NCT03976739
- Where
- China
- Volunteers
- 1,162 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Type 2 Diabetes Mellitus, Non-alcoholic Fatty Liver Disease
Efficacy of Pioglitazone Hydrochloride and Metformin Hydrochloride Tablets on the Patients With Newly Diagnosed Type 2 Diabetes Mellitus Combined With Non-alcoholic Fatty Liver Disease
This is an multicenter, randomized, double-blind, parallel-controlled study to evaluated the efficacy of pioglitazone hydrochloride and metformin hydrochloride tablets on the patients with newly diagnosed type 2 diabetes mellitus…
- Conditions
- Type 2 Diabetes Mellitus, Non-alcoholic Fatty Liver Disease, Efficacy
- Trial name
- NCT03796975
- Testing
- Combination of Pioglitazone and Metformin Tablets, Metformin Hydrochloride Tablets
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xijing Hospital
Heart Valve Diseases, Coronary Artery Disease
Dexmedetomidine and Outcomes of Cardiac Surgery (DOCS)
Cardiac surgery is associated with a high risk of cardiovascular and other complications. The investigators hypothesized that perioperative infusion of dexmedetomidine may reduce the incidence of complications and mortality…
- Trial name
- DOCS (NCT02237495)
- Testing
- dexmedetomidine
- Where
- China
- Volunteers
- 1,100 people
- Sponsor
- Xijing Hospital
Postoperative Cognitive Dysfunction
MD2, Cystatin C and DNA Methylation Tags as Serum Biomarkers for POCD.
Postoperative cognitive dysfunction (POCD) is a severe complication after surgery. Currently, a complicated battery of neuropsychological tests both before and after surgery with other characteristics-matched population as…
- Trial name
- BM-POCD (NCT03610191)
- Testing
- Serum biomarker tests, Neuropsychological battery tests, Cardiac surgery
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Xijing Hospital