Clinical trials: sponsored by Xijing Hospital
Neoplasms, Breast
Lapatinib Plus Chemotherapy Versus Trastuzumab Plus Chemotherapy in HER2-positive Breast Cancer
This is a prospective, open-label, real-word study evaluating the efficacy and safety of lapatinib in combination with chemotherapy versus trastuzumab in combination with chemotherapy in women with HER2-positive and…
- Trial name
- NCT03273595
- Testing
- Lapatinib, Trastuzumab, Paclitaxel
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xijing Hospital
Thyroid Cancer, Parathyroid; Absent
Intra-operative Rapid Identification of Lymph Node and Parathyroid
During surgery, a fine needle puncture was proceeded when suspicious nodes was found by clinician. Repeat the punction for 2-3 times from different orientation and then, Diff-quik staining or PTH immunochromatographic assay were…
- Conditions
- Thyroid Cancer, Parathyroid; Absent, Hypocalcemia, Hypoparathyroidism Postprocedural
- Trial name
- NCT03268785
- Testing
- Intraoperative identification method
- Where
- 2 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Cesarean Section
Transcutaneous Electrical Acupoint Stimulation on Gastrointestinal Function After Cesarean Section
To determine whether treating by transcutaneous electrical acupoint stimulation (TEAS) during perioperative could alleviate the postoperative gastrointestinal complications after cesarean section under combined spinal epidural…
- Trial name
- TEAS (NCT02416310)
- Testing
- TEAS
- Volunteers
- 150 people
- Sponsor
- Xijing Hospital
Establish the Incidence Rate of Abdominal and Cerebral Hyperoxemia and Hypoxemia Events in Neonates at Birth
Monitoring of Cerebral and Abdominal Tissue Oxygen Saturation in Neonates
Near-infrared spectroscopy (NIRS) functions in a manner similar to pulse oximetry, using the difference in absorptive qualities of oxy- and deoxyhemoglobin to infrared light to quantify the percent saturation.
- Trial name
- NCT03149731
- Testing
- NIRS
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xijing Hospital
Tissue Expansion
Study of Tissue Expansion Devices Complications
Reduce the common complications incidence about patients placed tissue expansion devices to around 5%.
- Trial name
- STEDC (NCT03084887)
- Testing
- manuals and follow-up
- Where
- China
- Volunteers
- 208 people
- Sponsor
- Xijing Hospital
Mild Cognitive Impairment
Application and Revision of Montreal Cognitive Assessment in Chinese Retirees
The study was designed to employ MOCA to screen mild cognitive impairment (MCI) in military retirees and to analyze the associated risk factors. As such, MOCA was revised to be validated for the Chinese context.
- Trial name
- ARMOCA (NCT02483754)
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Melanoma
18F-Labeled Picolinamide PET Imaging of Melanoma Diagnosis
The purpose of this study is to assess the dosimetric properties of the positron emission tomography (PET) imaging probe 18F labeled Picolinamide (18F-P3BZA) and preliminarily evaluate its diagnosis value in melanoma patients.
- Trial name
- NCT03033485
- Testing
- 18F-P3BZA
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xijing Hospital
Coronary Artery Disease
Clinical Performance of Nano Plus Sirolimus-Eluting Stents in Patients With Coronary Artery Disease
The study aims to evaluate the safety and efficacy of polymer-free sirolimus-eluting coronary stent system (NANO plus) in patients with coronary artery disease .
- Trial name
- NCT02929030
- Testing
- Nano
- Where
- China
- Volunteers
- 2,500 people
- Sponsor
- Xijing Hospital
Coronary Heart Disease
Different Dosage of Domestic and Imported Clopidogrel on the Platelet Inhibition Ratio in Patients Undergoing PCI
This is a single-center, randomized, single-blind, investigator-initiated, pharmacological study with a parallel design. Patients with non-ACS undergoing primary percutaneous coronary intervention will be randomized after…
- Trial name
- NCT03006835
- Testing
- Clopidogrel
- Volunteers
- 120 people
- Sponsor
- Xijing Hospital
Schizophrenia
Genes Polymorphisms and Metabolic Effects of the Second Generation Antipsychotic Drugs in Patients With Schizophrenia
The purpose of the study is to investigate these effects of Second-Generation Antipsychotic (SGAs) on glucose and lipid metabolic parameters in patients with schizophrenia, and explore the relationship between genes polymorphisms…
- Trial name
- NCT02964923
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Xijing Hospital
Hypertrophic Obstructive Cardiomyopathy
Echocardiography-guided Transthoracic Radio Frequency/Laser Ablation for Ventricular Septum of Hypertrophic Obstructive Cardiomyopathy
Hypertrophic Obstructive Cardiomyopathy (HOCM) patients have significant clinical symptoms, including progressively increasing fatigue, angina, exertional dyspnea, and syncope.
- Trial name
- NCT02888132
- Testing
- Echocardiography-guided transthoracic radio frequency ablation for HOCM ventricular septum, Echocardiography-guided transthoracic laser ablation for HOCM ventricular septum
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Xijing Hospital
Asthma
Clinical Study of Relationship Between Granulocyte Activation, HDAC2 and Severe Asthma
Program： Clinical Study of Relationship Between Granulocyte Activation, HDAC2 and Severe Asthma Aim：The early prediction of severe asthma, early intervention on the disease, reduce the family and the national finance.
- Trial name
- NCT02881502
- Testing
- severe asthma group
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Angina, Unstable, Non-ST-Segment Elevation Myocardial Infarction
OCT Based Edge and In-stent Vascular Response After Cordimax Stent in patIents With NSTE-ACS
This study evaluates the completeness of strut coverage and vessel wall response, at different time points (3-6-12 Months), following CordimaxTM stent implantation in patients with non-ST elevation acute coronary syndrome
- Trial name
- NCT02868203
- Testing
- OCT, eLuting stent
- Volunteers
- 80 people
- Sponsor
- Xijing Hospital
Liver Metastases
A Study of MG7 Redirected Autologous T Cells for Advanced MG7 Positive Liver Metastases(MG7-CART)
The purpose of this study is to collect the data on the safety and potential effectiveness of intra-tumor injection of MG7-CART cells under ultrasound guidance in patients with liver metastases expressing MG7 positively.
- Trial name
- NCT02862704
- Testing
- MG7-CART
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Xijing Hospital
Complication of Ventilation Therapy, Intubation Complication
Bronchial Blocker for One-lung Ventilation in Cardiac Surgery
To investigate if bronchial blocker is more suitable for one-lung ventilation during thoracoscope assisted mitral valve replacement surgery with Cardiopulmonary Bypass than the double-lumen endobronchial tube.
- Conditions
- Complication of Ventilation Therapy, Intubation Complication, Postoperative; Dysfunction Following Cardiac Surgery
- Trial name
- NCT02729610
- Testing
- double-lumen endotracheal tube (DLT group), endobronchial blocker (BB group)
- Volunteers
- 58 people
- Sponsor
- Xijing Hospital
Blood Loss
The Efficacy and Safety of Using Tranexamic Acid by Different Means to Reduce Blood Loss During Total Knee Replacement
We will investigate the efficacy and safety of using tranexamic acid by intravenous, intra-articular and combinational administration to reduce blood loss during total knee replacement.
- Trial name
- NCT02117128
- Testing
- Tranexamic acid
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Xijing Hospital
Blood Loss
The Efficacy and Safety of Using Tranexamic Acid to Reduce Blood Loss In Simultaneous Bilateral Total Knee Arthroplasty
A randomized, double-blind, single-center and controlled study comparing the efficacy and safety of intravenous administration of tranexamic acid to reduce blood loss in simultaneous bilateral total knee arthroplasty.
- Trial name
- NCT02504125
- Testing
- Tranexamic Acid, Normal saline
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xijing Hospital
Gout
Safety and Efficacy of Oral Febuxostat in Subjects With Gout
The purpose of this study is to compare febuxostat allopurinol in subjects with gout.
- Trial name
- NCT02082769
- Testing
- Febuxostat, Allopurinol
- Volunteers
- 504 people
- Sponsor
- Xijing Hospital
Aorta Dissection, Aorta Aneurysm
Total Endovascular Aortic Arch Re-construction Study(TEARS)
The purpose of this study is to investigate the short to mid term efficacy and safety of a newly-developed branched stent graft in patients who had complex aortic lesions, such as ascending aortic/arch aneurysm, pseudo-aneurysm…
- Trial name
- NCT01496833
- Testing
- Ankura Branched/Fenestrated Stent Graft
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xijing Hospital
Aorta Dissection, Aorta Aneurysm
Hybrid Operation in Thoracic Aortic Dissection
The purpose of this study is to investigate the short to mid term efficacy and safety of different hybrid operations who had complex aortic lesions, such as ascending aortic/arch aneurysm, pseudo-aneurysm, Stanford Type A…
- Trial name
- NCT01500395
- Testing
- Hybrid operation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xijing Hospital