Clinical trials: sponsored by Xijing Hospital
Type 2 Diabetes Mellitus
A Comparative Study of the Effects of QS-M Needle Free Injector and Glargine Pen Subcutaneous Injection of Insulin Glargine on Insulin Use
A clinical study of the use of glargine insulin in 2 subjects with type two diabetes in China was carried out. The two kinds of injection methods were evaluated as subcutaneous injection of insulin glargine.
- Trial name
- NCT03420040
- Testing
- QS-M Needle Free Injector, Glargine pen
- Where
- China
- Volunteers
- 65 people
- Sponsor
- Xijing Hospital
Scar
Early Postoperative Prevention and Treatment of Median Sternotomy Scars With Botulinum Toxin Type A Injection
Linear hypertrophic scar is a common surgical problem that can be difficult to manage, especially for the median sternotomy scar.
- Trial name
- NCT02886988
- Testing
- Botulinum toxin type A, normal saline
- Where
- China
- Volunteers
- 17 people
- Sponsor
- Xijing Hospital
Colorectal Cancer
The Clinical Application of 68Ga Labeled ssDNA Aptamer Sgc8 in Healthy Volunteers and Colorectal Patients
The protein tyrosine kinase-7 (PTK7) is overexpressed in various types of human cancers. As a specific imaging agent of PTK7, 68Ga-Sgc8 was investigated in this study to assess its safety, biodistribution and dosimetric…
- Trial name
- NCT03385148
- Testing
- 68Ga-Sgc8
- Where
- 2 sites in China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Cluster Headache
Efficacy and Safety of Zolmitriptan by Sublingual Administration
The purpose is to evaluate the effectiveness and safety profile of zolmitriptan by Sublingual administration for the acute treatment of Cluster headache.
- Trial name
- NCT03377257
- Testing
- zolmitriptan by sublingual administration, zolmitriptan by oral
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Breast Reconstruction
Immediate Breast Reconstruction With Free Greater Omentum
Luminal subtype breast cancer, accounting for 70 to 80% of all breast cancers, has been reported to be associated with good prognosis.
- Trial name
- NCT03370250
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Xijing Hospital
Bone Defect, Bone Nonunion
The Clinical Therapeutic Effects and Safety of Tissue-engineered Bone
The purpose of this study is to compare use of a tissue-engineered bone to use of a standard allograft bone to treat bone defect in patients.
- Trial name
- NCT02748343
- Testing
- allograft bone, tissue-engineered bone
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Xijing Hospital
Neoplasms, Breast
Lapatinib Plus Chemotherapy Versus Trastuzumab Plus Chemotherapy in HER2-positive Breast Cancer
This is a prospective, open-label, real-word study evaluating the efficacy and safety of lapatinib in combination with chemotherapy versus trastuzumab in combination with chemotherapy in women with HER2-positive and…
- Trial name
- NCT03273595
- Testing
- Lapatinib, Trastuzumab, Paclitaxel
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xijing Hospital
Thyroid Cancer, Parathyroid; Absent
Intra-operative Rapid Identification of Lymph Node and Parathyroid
During surgery, a fine needle puncture was proceeded when suspicious nodes was found by clinician. Repeat the punction for 2-3 times from different orientation and then, Diff-quik staining or PTH immunochromatographic assay were…
- Conditions
- Thyroid Cancer, Parathyroid; Absent, Hypocalcemia, Hypoparathyroidism Postprocedural
- Trial name
- NCT03268785
- Testing
- Intraoperative identification method
- Where
- 2 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Cesarean Section
Transcutaneous Electrical Acupoint Stimulation on Gastrointestinal Function After Cesarean Section
To determine whether treating by transcutaneous electrical acupoint stimulation (TEAS) during perioperative could alleviate the postoperative gastrointestinal complications after cesarean section under combined spinal epidural…
- Trial name
- TEAS (NCT02416310)
- Testing
- TEAS
- Volunteers
- 150 people
- Sponsor
- Xijing Hospital
Stomach Neoplasms
The Efficacy of Esomeprazole Premedication on Intraoperative Bleeding During Gastric ESD
This will be a single-centre, randomised, endoscopist-blind, parallel-group study in patients who are scheduled endoscopic submucosal dissection (ESD) for gastric mucosal lesion.
- Trial name
- NCT02730533
- Testing
- Esomeprazole, No PPI treatment
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Establish the Incidence Rate of Abdominal and Cerebral Hyperoxemia and Hypoxemia Events in Neonates at Birth
Monitoring of Cerebral and Abdominal Tissue Oxygen Saturation in Neonates
Near-infrared spectroscopy (NIRS) functions in a manner similar to pulse oximetry, using the difference in absorptive qualities of oxy- and deoxyhemoglobin to infrared light to quantify the percent saturation.
- Trial name
- NCT03149731
- Testing
- NIRS
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xijing Hospital
Ulcerative Colitis, Unspecified
Mesalazine With Hydrocortisone Sodium Succinate Enema for 4-Week Treatment in Patients With Ulcerative Colitis
The research aims to evaluate the efficacy and safety of that mesalazine with hydrocortisone sodium succinate for the induction of clinical remission during a 4-week double-blind treatment period in active UC (define as total…
- Trial name
- NCT03110198
- Testing
- Mesalazine, hydrocortisone sodium succinate, Mesalazine with hydrocortisone sodium succinate
- Where
- China
- Volunteers
- 528 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Fascial Closure
A New Abdomen Closure Technology Based on Component Separation: a Prospective Randomized Controlled Trial
At present, open-type abdominal surgery is routine access into the abdomen. Median incision is the common choice with open-type abdominal surgery. Layered abdomen-closing is often used at the end-time of the surgery.
- Trial name
- NCT03111134
- Testing
- modified component separation technique
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Tissue Expansion
Study of Tissue Expansion Devices Complications
Reduce the common complications incidence about patients placed tissue expansion devices to around 5%.
- Trial name
- STEDC (NCT03084887)
- Testing
- manuals and follow-up
- Where
- China
- Volunteers
- 208 people
- Sponsor
- Xijing Hospital
Mild Cognitive Impairment
Application and Revision of Montreal Cognitive Assessment in Chinese Retirees
The study was designed to employ MOCA to screen mild cognitive impairment (MCI) in military retirees and to analyze the associated risk factors. As such, MOCA was revised to be validated for the Chinese context.
- Trial name
- ARMOCA (NCT02483754)
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Melanoma
18F-Labeled Picolinamide PET Imaging of Melanoma Diagnosis
The purpose of this study is to assess the dosimetric properties of the positron emission tomography (PET) imaging probe 18F labeled Picolinamide (18F-P3BZA) and preliminarily evaluate its diagnosis value in melanoma patients.
- Trial name
- NCT03033485
- Testing
- 18F-P3BZA
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xijing Hospital
Gastritis, Peptic Ulcer
Helicobacter Pylori Eradication With Berberine Quadruple Therapy Versus Clarithromycin Quadruple Therapy
This study aims at evaluating efficacy and safety of berberine-containing quadruple therapy(berberine, lansoprazole, bismuth and amoxicillin) versus clarithromycin-containing quadruple therapy (clarithromycin,lansoprazole…
- Conditions
- Gastritis, Peptic Ulcer, Dyspepsia
- Trial name
- NCT02633930
- Testing
- Berberine, clarithromycin, Bismuth
- Where
- 2 sites in China
- Volunteers
- 566 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Coronary Artery Disease
Clinical Performance of Nano Plus Sirolimus-Eluting Stents in Patients With Coronary Artery Disease
The study aims to evaluate the safety and efficacy of polymer-free sirolimus-eluting coronary stent system (NANO plus) in patients with coronary artery disease .
- Trial name
- NCT02929030
- Testing
- Nano
- Where
- China
- Volunteers
- 2,500 people
- Sponsor
- Xijing Hospital
Coronary Heart Disease
Different Dosage of Domestic and Imported Clopidogrel on the Platelet Inhibition Ratio in Patients Undergoing PCI
This is a single-center, randomized, single-blind, investigator-initiated, pharmacological study with a parallel design. Patients with non-ACS undergoing primary percutaneous coronary intervention will be randomized after…
- Trial name
- NCT03006835
- Testing
- Clopidogrel
- Volunteers
- 120 people
- Sponsor
- Xijing Hospital
Schizophrenia
Genes Polymorphisms and Metabolic Effects of the Second Generation Antipsychotic Drugs in Patients With Schizophrenia
The purpose of the study is to investigate these effects of Second-Generation Antipsychotic (SGAs) on glucose and lipid metabolic parameters in patients with schizophrenia, and explore the relationship between genes polymorphisms…
- Trial name
- NCT02964923
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Xijing Hospital