Clinical trials: sponsored by Xijing Hospital
Primary Biliary Cirrhosis
Fuzhenghuayu for Patients With PBC Who Had An Inadequate Response to Ursodeoxycholic Acid
Ursodeoxycholic acid (UDCA) has been the only treatment for PBC approved by US and European drug administrations. Long-term use of UDCA(13-15 mg/kg/day) in patients with PBC improves serum liver biochemistries and survival free…
- Trial name
- NCT02916641
- Testing
- Fuzhenghuayu, UDCA
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Primary Biliary Cirrhosis
Fuzhenghuayu in Combination With Ursodeoxycholic Acid in Primary Biliary Cirrhosis
Ursodeoxycholic acid (UDCA) has been the only treatment for PBC approved by US and European drug administrations. Long-term use of UDCA (13-15 mg/kg/day) in patients with PBC improves serum liver biochemistries and survival free…
- Trial name
- NCT02916290
- Testing
- Fuzhenghuayu, UDCA
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Hypertrophic Obstructive Cardiomyopathy
Echocardiography-guided Transthoracic Radio Frequency/Laser Ablation for Ventricular Septum of Hypertrophic Obstructive Cardiomyopathy
Hypertrophic Obstructive Cardiomyopathy (HOCM) patients have significant clinical symptoms, including progressively increasing fatigue, angina, exertional dyspnea, and syncope.
- Trial name
- NCT02888132
- Testing
- Echocardiography-guided transthoracic radio frequency ablation for HOCM ventricular septum, Echocardiography-guided transthoracic laser ablation for HOCM ventricular septum
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Xijing Hospital
Asthma
Clinical Study of Relationship Between Granulocyte Activation, HDAC2 and Severe Asthma
Program： Clinical Study of Relationship Between Granulocyte Activation, HDAC2 and Severe Asthma Aim：The early prediction of severe asthma, early intervention on the disease, reduce the family and the national finance.
- Trial name
- NCT02881502
- Testing
- severe asthma group
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Angina, Unstable, Non-ST-Segment Elevation Myocardial Infarction
OCT Based Edge and In-stent Vascular Response After Cordimax Stent in patIents With NSTE-ACS
This study evaluates the completeness of strut coverage and vessel wall response, at different time points (3-6-12 Months), following CordimaxTM stent implantation in patients with non-ST elevation acute coronary syndrome
- Trial name
- NCT02868203
- Testing
- OCT, eLuting stent
- Volunteers
- 80 people
- Sponsor
- Xijing Hospital
Liver Metastases
A Study of MG7 Redirected Autologous T Cells for Advanced MG7 Positive Liver Metastases(MG7-CART)
The purpose of this study is to collect the data on the safety and potential effectiveness of intra-tumor injection of MG7-CART cells under ultrasound guidance in patients with liver metastases expressing MG7 positively.
- Trial name
- NCT02862704
- Testing
- MG7-CART
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Xijing Hospital
Complication of Ventilation Therapy, Intubation Complication
Bronchial Blocker for One-lung Ventilation in Cardiac Surgery
To investigate if bronchial blocker is more suitable for one-lung ventilation during thoracoscope assisted mitral valve replacement surgery with Cardiopulmonary Bypass than the double-lumen endobronchial tube.
- Conditions
- Complication of Ventilation Therapy, Intubation Complication, Postoperative; Dysfunction Following Cardiac Surgery
- Trial name
- NCT02729610
- Testing
- double-lumen endotracheal tube (DLT group), endobronchial blocker (BB group)
- Volunteers
- 58 people
- Sponsor
- Xijing Hospital
Gastrointestinal Imaging With pCLE
Effect of Buscopan on Gastrointestinal Imaging Quality With Probe-based Confocal Laser Endomicroscopy
Gastrointestinal cancer has developed into a serious health problem in China. 80%-90% patients were detected at middle and later stage. The five-year survival rate for advanced cancer patients is less than 10%.
- Trial name
- NCT02725398
- Testing
- Buscopan, Scopolamine, physiological saline
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Esophageal Neoplasms
Pronase Improves Efficacy of Chromoendoscopy Screening on Esophageal Cancer
Lugol's solution staining was regarded as a gold standard to detect early superficial lesion during esophageal cancer screening using endoscopy.
- Trial name
- NCT02030769
- Testing
- Pronase, Control
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Early Gastric Cancer
The Feasible Research of Infrared Endoscope to Diagnose Early Gastric Cancer
The gastric cancer is the second most frequently diagnosed cancer and the third leading cause of cancer death in China.80%-90% patients were detected at middle and later stage.The five-year survival rate for advanced gastric…
- Trial name
- NCT02710838
- Testing
- infrared endoscopy
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Blood Loss
The Efficacy and Safety of Using Tranexamic Acid to Reduce Blood Loss In Simultaneous Bilateral Total Knee Arthroplasty
A randomized, double-blind, single-center and controlled study comparing the efficacy and safety of intravenous administration of tranexamic acid to reduce blood loss in simultaneous bilateral total knee arthroplasty.
- Trial name
- NCT02504125
- Testing
- Tranexamic Acid, Normal saline
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xijing Hospital
Blood Loss
The Efficacy and Safety of Using Tranexamic Acid by Different Means to Reduce Blood Loss During Total Knee Replacement
We will investigate the efficacy and safety of using tranexamic acid by intravenous, intra-articular and combinational administration to reduce blood loss during total knee replacement.
- Trial name
- NCT02117128
- Testing
- Tranexamic acid
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Xijing Hospital
Gout
Safety and Efficacy of Oral Febuxostat in Subjects With Gout
The purpose of this study is to compare febuxostat allopurinol in subjects with gout.
- Trial name
- NCT02082769
- Testing
- Febuxostat, Allopurinol
- Volunteers
- 504 people
- Sponsor
- Xijing Hospital
Ischemic Stroke
The Diagnosis Value of Serum Marker in Stroke Associated With Nonvalvular Atrial Fibrillation.
The purpose of this study is to evaluate the diagnostic value of serum NT - proBNP in stroke associated with nonvalvular atrial fibrilltion.
- Trial name
- CE (NCT02181374)
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Xijing Hospital
Delirium, Hemodynamic Instability
Target Controlled Infusion of Etomidate or Propofol for Anesthesia of Thoracoscopic Mitral Valve Replacement Surgery
For patients requiring the heart valve replacement surgery, heart function is injured in different degree.Thus, minimizing the impact of the anesthesia drug on the cardiovascular system has important clinical meanings.
- Trial name
- NCT02644980
- Testing
- Propofol, Etomidate, Bispectral Index Monitor
- Volunteers
- 110 people
- Sponsor
- Xijing Hospital
Aorta Dissection, Aorta Aneurysm
Hybrid Operation in Thoracic Aortic Dissection
The purpose of this study is to investigate the short to mid term efficacy and safety of different hybrid operations who had complex aortic lesions, such as ascending aortic/arch aneurysm, pseudo-aneurysm, Stanford Type A…
- Trial name
- NCT01500395
- Testing
- Hybrid operation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xijing Hospital
Migraine
Efficacy and Safety of Danzhen
The purpose is to evaluate the effectiveness and safety profile of Danzhen for the prophylaxis of migraine in a "real-world" setting.
- Trial name
- NCT02645370
- Testing
- Danzhen, Topiramate
- Where
- China
- Volunteers
- 3,300 people
- Sponsor
- Xijing Hospital
Aorta Dissection, Aorta Aneurysm
Endovascular Aortic Repair for Aortic Dissection
The purpose of this study is to investigate the short to mid term efficacy and safety of Thoracic Endovascular Aortic Repair (TEVAR) in patients who had aortic lesions, such as descending aortic/arch aneurysm, pseudo-aneurysm…
- Trial name
- NCT01505309
- Testing
- Stent Graft (Medtronic, Microport, Ankura)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Xijing Hospital
Infection
Biological Markers for the Diagnosis of Central Nervous System Infective Diseases
Bacterial meningitis is a potentially life-threatening disease that is associated with substantial neurological morbidity and mortality. Accurate diagnosis is essential to improve outcome and prevent antibiotic overuse.
- Trial name
- NCT02278016
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Status Epileptics
Assessment of Severity and Prognosis for Patients With Status Epileptics(SE)
To characterize the functional outcomes and prognostic factors for convulsive status epilepticus (SE) and to further develop and validate a simple and practicable scoring system for outcome prediction.
- Trial name
- NCT02269137
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xijing Hospital