Clinical trials: sponsored by Xijing Hospital
Oliceridine Fumarate
Effect of Postoperative Analgesia of Oliceridine Fumarate for Gastrointestinal Function Recovery in Patients Undergoing Lumbar Spine Surgery
Osemitidine fumarate is a novel G protein-biased ligand μ-opioid receptor agonist. Previous studies have confirmed its potent analgesic effects and safety: compared with morphine, it reduces respiratory depression and…
- Trial name
- NCT07307495
- Testing
- Sufentanil, Oiceridine
- Where
- China
- Volunteers
- 428 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Postoperative Delirium, Acute Kidney Injury
Correlation Between Preoperative Sleep and Postoperative Brain and Renal Dysfunction
To explore the correlation between preoperative sleep parameter clustering and postoperative brain and renal dysfunction.
- Trial name
- NCT07518992
- Where
- China
- Volunteers
- 549 people
- Sponsor
- Xijing Hospital
Postoperative Delirium
Postoperative Delirium in Patients Undergoing Cardiac Surgery
Establish a follow-up database for postoperative delirium in cardiac surgery patients, adopt a bidirectional cohort design to simultaneously analyze the associations between "preoperative exposure factors and postoperative…
- Trial name
- NCT07239648
- Testing
- Serum metabolic profile
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Xijing Hospital
Adult Patients Undergoing CABG
Effect of Preoperative Stellate Ganglion Block on Postoperative Atrial Fibrillation After Coronary Artery Bypass Grafting
The primary objective of this study is to determine the feasibility of preoperative stellate ganglion block in reducing the incidence of postoperative atrial fibrillation in patients undergoing CABG.
- Trial name
- NCT07271615
- Testing
- Stellate Ganglion Block
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xijing Hospital
Epilepsy, Psychogenic Non-epileptic Seizures
Study on the Rapid Diagnostic Value of Sudden Clap Provocation Test in Psychogenic Nonepileptic Seizures
To explore the clinical value of the sudden clap provocation test in the differential diagnosis between epileptic seizures and psychogenic non-epileptic seizures, so as to provide a new strategy for rapid, low-cost differential…
- Trial name
- PNES ACPT (NCT07742709)
- Testing
- Abrupt Clap Provocation Test
- Where
- 3 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Cervical Spinal Stenosis, Posterior Cervical Spine Surgery
Researching the Useful of Barb Suture in Obese Patients Undergoing Posterior Cervical Surgery
Through a single-center, exploratory clinical study, the safety and effectiveness of using barb wire in the incision and suture of posterior cervical surgery in obese patients were evaluated, providing a basis for its wide…
- Conditions
- Cervical Spinal Stenosis, Posterior Cervical Spine Surgery, Barbed Suture
- Trial name
- NCT05895968
- Testing
- posterior cervical surgery
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xijing Hospital
Ischemic Stroke
Antithrombotic Drug Use in Patients With Ischemic Stroke and Microbleeds
To observe the effect of different antithrombotic drugs on the prognosis of ischemic stroke patients with cerebral microbleeds. And further combined with proteomic methods to explore serological markers that can be used to…
- Trial name
- AIM-2 (NCT05032053)
- Testing
- Antithrombotic drugs
- Where
- 16 sites in China
- Volunteers
- 3,000 people
- Sponsor
- Xijing Hospital
Cervical Spinal Stenosis, Cervical Spinal Cord Injury
Study of Individualized, Precise and Standardized Cervical Open-door Surgery for Cervical Spinal Stenosis
To evaluate the safety and effectiveness of individualized, precise and standardized open-door posterior cervical surgery through a single-center, exploratory clinical study, so as to provide a more reliable basis for the…
- Conditions
- Cervical Spinal Stenosis, Cervical Spinal Cord Injury, Individuation, Standardization
- Trial name
- NCT05786313
- Testing
- Centerpiece titanium plate
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Xijing Hospital
Platelets-rich Plasma, Osteoarthritis Knees Both
Effect of Platelet-rich Plasma (PRP) Injection on Knee Osteoarthritis
To evaluate the safety and effectiveness of PRP injection therapy in the repair of osteoarthritis and periarticular soft tissue injury through a single-center, exploratory clinical study, and to provide a more reliable basis for…
- Conditions
- Platelets-rich Plasma, Osteoarthritis Knees Both, Meniscus Disorder, Cartilage Injury
- Trial name
- NCT06082531
- Testing
- Sodium hyaluronate injection
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Xijing Hospital
Prostate Cancer
Plasma Exosome RNA to Diagnose Prostate Cancer
The aim of the present study is to investigate a RNA combination to diagnose prostate cancer.
- Trial name
- exo-PRECISE (NCT06604130)
- Testing
- Prostate cancer screening decision
- Where
- 9 sites in China
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Cervical Spinal Stenosis
Correlation Between Parameters and Prognosis of Cervical Single Open-door Surgery
The aim of study was evaluated the relationship between the relevant evaluation indexes of cervical spine open-door surgery, prognosis and complication rate, and provided theoretical basis for personalized surgical program…
- Trial name
- NCT05767164
- Testing
- cervical single open-door surgery
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Xijing Hospital
Ischemic Stroke, Acute
Effects of Minocycline on Patients With Ischemic Stroke Undergoing Intravenous Thrombectomy
Minocycline is the second generation of tetracycline. Because of its lipophilicity, it has high penetrance of blood-brain barrier.
- Trial name
- MIST-A (NCT05487417)
- Testing
- Minocycline
- Where
- China
- Volunteers
- 189 people
- Sponsor
- Xijing Hospital
Primary Biliary Cholangitis (PBC)
Fenofibrate in Subjects With Primary Biliary Cholangitis (PBC)
An Open Label Long-Term Study to Evaluate the Safety and Tolerability of Fenofibrate in Subjects with Primary Biliary Cholangitis (PBC)
- Trial name
- NCT07104201
- Testing
- Fenofibrate
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Insomnia
A Study of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for Insomnia During Pregnancy
The goal of this clinical trial is to learn whether transcutaneous auricular vagus nerve stimulation (taVNS) can treat insomnia during pregnancy. It will also learn about the safety of taVNS for pregnant women and their fetuses.
- Trial name
- NCT07730762
- Testing
- transcutaneous auricular vagus nerve stimulation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xijing Hospital
Narcolepsy Type 1 (NT 1), Hypersomnolence Disorder
Radar Sleep Monitoring in Type 1 Narcolepsy: Feasibility
This study aims to evaluate the clinical feasibility of a millimeter-wave radar sleep monitoring system in the diagnosis of Narcolepsy Type 1 (NT1).
- Trial name
- NCT07654803
- Where
- China
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Ischemic Stroke
Early Neurovascular Decoupling Trajectories After Revascularization in Acute Ischemic Stroke
Background: Recanalization therapy is the standard treatment for acute ischemic stroke (AIS), yet patient outcomes remain highly heterogeneous. The underlying mechanisms of this variability are not fully understood.
- Trial name
- MAP-END (NCT07405762)
- Testing
- Multimodal Neuromonitoring
- Where
- 2 sites in China
- Volunteers
- 180 people
- Sponsor
- Xijing Hospital
Hypertrophic Cardiomyopathy, Obstructive
Percutaneous Intramyocardial Septal Radiofrequency Ablation for Obstructive Hypertrophic Cardiomyopathy in Children
The primary purpose of this study was to demonstrate the safety and efficacy of percutaneous intramyocardial septal radiofrequency ablation (PIMSRA) in children and assessed its performance and functional outcomes in the…
- Trial name
- NCT06540183
- Testing
- Percutaneous intramyocardial septal radiofrequency ablation
- Where
- China
- Volunteers
- 23 people
- Sponsor
- Xijing Hospital
Disorders of Consciousness Due to Severe Brain Injury
Hand Jing-Well Points Stimulation to Treat Disorders of Consciousness
The purpose of this academic lead study is to explore the ideal stimulation strategies at Hand twelve jing-well points in patients with disorders of consciousness.
- Trial name
- Wells-DoC (NCT06927713)
- Testing
- Bloodletting Acupuncture, Transcutaneous electrical stimulation
- Where
- 4 sites in China
- Volunteers
- 59 people
- Sponsor
- Xijing Hospital
Perioperative Neurocognitive Disorders
The Effect of Esketamine on Postoperative Cognitive Function in Elderly Patients Undergoing Oral and Maxillofacial Surgery
Esketamine is a common anesthetic adjuvant. Previous studies have shown that it may have protective effects on the brain. This study aims to investigate whether esketamine can improve cognitive function recovery in elderly…
- Trial name
- NCT07665099
- Testing
- esketamine, Normal Saline
- Where
- China
- Volunteers
- 98 people
- Sponsor
- Xijing Hospital
IBD (Inflammatory Bowel Disease), Combined Advanced Targeted Therapy
Combined Advanced Targeted Therapy for Inflammatory Bowel Disease
The aim of this retrospective and prospective observational study is to investigate and compare the real-world effectiveness and safety of different dual-target combination therapies in patients with inflammatory bowel disease…
- Conditions
- IBD (Inflammatory Bowel Disease), Combined Advanced Targeted Therapy, Combination Therapy
- Trial name
- NCT07660289
- Testing
- Combination therapy
- Where
- China
- Volunteers
- 117 people
- Sponsor
- Xijing Hospital of Digestive Diseases