Clinical trials: sponsored by Xuanwu Hospital, Beijing
Acute Ischemic Stroke, Endovascular Thrombectomy
A Predictive Model and Scoring System for Severe Complications After Endovascular Thrombectomy
To establish a predictive model and scoring system for predicting severe complications after thrombectomy. This scoring system can be used to identify high-risk patients after endovascular thrombectomy, guide the early use of…
- Conditions
- Acute Ischemic Stroke, Endovascular Thrombectomy, Symptomatic Intracranial Hemorrhage, Malignant Cerebral Edema
- Trial name
- NCT06290076
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Xuanwu Hospital, Beijing
Syringomyelia, Thalidomide
The Therapeutic Effect of Thalidomide in Syringomyelia
Purpose: This phase II clinical trial aims to evaluate the indications, therapeutic effects and side effects of thalidomide in refractory syringomyelia.
- Trial name
- NCT06268093
- Testing
- Thalidomide
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Xuanwu Hospital, Beijing
Immunotherapy, ADR
A Prospective Study to Observe Adverse Effects in Patients Receiving Anti-PD1 Immunotherapy
The goal of this observational study is to learn about in the development process of adverse reactions of anti-PD1 immunotherapy.
- Trial name
- NCT05669638
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Xuanwu Hospital, Beijing
Parkinson Disease, Freezing of Gait
Vibrotactile Foot Device for Freezing of Gait in Parkinson's Disease
Freezing of gait (FOG) is a common, disabling symptom of later stage Parkinson's disease (PD), and can induce significant morbidity and mortality by increasing risk of falls as the disease progresses.
- Trial name
- NCT06147713
- Testing
- Vibrotactile foot device (Smart shoe)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xuanwu Hospital, Beijing
Stroke, Acute Ischemic Stroke
The MRI-based Evaluation of Safety and Efficacy of EVT and SMT: A Retrospective, Multicenter Study
Acute Basilar Artery Occlusion (ABAO), a condition with a high risk of mortality or disability (up to 80%). The safety and efficacy of endovascular thrombectomy (EVT) in ABAO remains uncertain due to inconsistent evidence from…
- Conditions
- Stroke, Acute Ischemic Stroke, Ischemic Stroke
- Trial name
- NCT06236828
- Testing
- Mechanical Thrombectomy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xuanwu Hospital, Beijing
Major Depressive Disorder
Transcranial Alternating Current Stimulation (tACS) on Serotonin-1A Receptor in Depression
This study will apply a comprehensive tools that integrates neuroimaging, psychological evaluation, and sleep monitoring through 18F-MPPF PET/MR, neuropsychological tests, and polysomnography (PSG) to explore the neurobiological…
- Trial name
- NCT06211140
- Testing
- tACS, Control
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Treatment-Resistant Depression
Transcranial Alternating Current Stimulation for Treatment-Resistant Depression
This trial aims to investigate the effect of twice-daily 15 mA transcranial alternating current stimulation (tACS) through three conductive electrodes attached to the scalp in subjects with treatment-resistant depression (TRD).
- Trial name
- NCT06172413
- Testing
- transcranial alternating current stimulation (tACS)
- Volunteers
- 200 people
- Sponsor
- Xuanwu Hospital, Beijing
Carotid Artery Stenting, Carotid Endarterectomy
Efficacy and Prognosis of Surgical Intervention in Patients With Carotid Artery Stenosis
This study is a prospective, single center cohort study. By combining pathological examination of carotid atherosclerotic plaque with preoperative imaging examination, we explore the imaging characteristics of high-risk carotid…
- Conditions
- Carotid Artery Stenting, Carotid Endarterectomy, Carotid Artery Plaque
- Trial name
- NCT06222983
- Testing
- CEA or CAS
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xuanwu Hospital, Beijing
Arterial Disease of Legs, Atherosclerosis of Artery
Safety and Efficacy of Cold Laser Plaque Ablation for Lower Limb Arterial Stenosis and Occlusive Lesions
This study is a prospective, multi-center, randomized controlled study, which evaluates the effectiveness and safety of cold laser plaque ablation for lower limb arterial stenosis and occlusive lesions from intermittent…
- Trial name
- NCT06211127
- Testing
- Cold laser plaque ablation, The excimer laser
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Xuanwu Hospital, Beijing
Mild Cognitive Impairment
Nurse-led Clinics Training Program on Mild Cognitive Impairment Patients
This trail is the first study to test the efficacy of nurse-led clinics cognitive training on mild cognitive impairment (MCI) patients using a single-blind, randomized controlled trial design.
- Trial name
- NCT06198530
- Testing
- cognitive training in NLCs, cognitive training in home, cognitive training in tradition
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Xuanwu Hospital, Beijing
Diabetic Retinopathy
Study on Exosome Changes in Patients With Proliferative Diabetic Retinopathy
Diabetic retinopathy is a common complication of diabetes and one of the leading causes of low vision and blindness in adults. In recent years, the prevalence of diabetes and the incidence of diabetic retinopathy have increased…
- Trial name
- NCT06198543
- Volunteers
- 60 people
- Sponsor
- Xuanwu Hospital, Beijing
Recurrent Adult Tethered Cord Syndrome
A Randomized Controlled Trial for Surgical Treatment of Recurrent Adult Tethered Cord Syndrome
This trial compares detethering surgery and spinal column shortening surgery, two treatments for adults with recurrent tethered cord syndrome (TCS), a neurological disorder where the spinal cord becomes abnormally attached to…
- Trial name
- NCT06197399
- Testing
- Detethering Surgery, Spinal Column Shortening Surgery
- Where
- China
- Volunteers
- 222 people
- Sponsor
- Xuanwu Hospital, Beijing
Stroke, Ischemic, Intracranial Atherosclerosis
Effects of Medical Treatment of ICAS With Hemodynamic Disorders Based on MR-FFR
This multicenter prospective cohort study aims to compare the difference in the effects of medical treatment within 1 year between the two groups of ICAS patients divided hemodynamically by Magnetic Resonance Fractional Flow…
- Trial name
- NCT06196398
- Testing
- Standard Medical Treatment on the basis of anti-platelet therapy
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Xuanwu Hospital, Beijing
Diabetic Retinopathy
Proteomic Study of Plasma Exosomes in Patients With Diabetic Retinopathy
Objective: Explore the biomarkers related to proliferative diabetic retinopathy by analyzing the protein expression profile changes of plasma exosomes in patients with difference phases of diabetic retinopathy, and investigate…
- Trial name
- NCT06188013
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Severe Brain Injury
Chinese Severe Brain Injury Trial
Building a Large Chinese Cohort(Chinese Severe brain injury Trial）
- Trial name
- CSBIT (NCT06179836)
- Volunteers
- 3,000 people
- Sponsor
- Xuanwu Hospital, Beijing
Chordoma, Chemotherapy Effect
Apatinib Combined With Camrelizumab in Treating Participants With Advanced Chordoma
This phase II trial studies how well Camrelizumab combined with Apatinib work in treating participants with chordoma that has spread to other places in the body, which may interfere with the ability of tumor cells to grow and…
- Trial name
- NCT06140732
- Testing
- camrelizumab and apatinib
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Acute Ischemic Stroke
Short-term Effect of PCSK9 Inhibitor in Patients With Acute Ischemic Stroke
This is a prospective cohort study to investigate the early impact of evolocumab on patients with acute ischemic stroke (AIS) in China.
- Trial name
- NCT06134635
- Testing
- Statins, Evolocumab
- Volunteers
- 80 people
- Sponsor
- Xuanwu Hospital, Beijing
Stroke, Acute Ischemic Stroke
The Safety and Efficacy of Embotrap in Treating Acute Ischemic Stroke Patients
This is a prospective, multicenter, cohort study aiming to compare the safety and efficacy of Embotrap stent retriever to other stent retrievers without inner channel for acute middle cerebral artery occlusion (MCAO).
- Trial name
- NCT05667103
- Testing
- Embotrap stent retriever, Solitaire FR, Trevo stent retriever without inner channel
- Where
- China
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Acute Ischemic Stroke
Impact of an Immune Modulator Dimethyl Fumarate on Acute Ischemic Stroke
The investigators conduct this study to investigate whether oral administration of Dimethyl Fumarate, a Food and Drug Administration-approved drug for multiple sclerosis, is safe and effective in in alleviating neurologic…
- Trial name
- NCT04890353
- Testing
- Dimethyl fumarate
- Where
- China
- Volunteers
- 2 people
- Sponsor
- Xuanwu Hospital, Beijing
Acute Ischemic Stroke
Combination of the Immune Modulator Dimethyl Fumarate With Intraarterial Treatment in Acute Ischemic Stroke
The investigators conduct this study to investigate whether oral administration of Dimethyl Fumarate, a Food and Drug Administration-approved drug for multiple sclerosis, is safe and effective in combination with intraarterial…
- Trial name
- NCT04891497
- Testing
- Dimethyl Fumarate
- Sponsor
- Xuanwu Hospital, Beijing