Clinical trials: sponsored by Xuanwu Hospital, Beijing
Alzheimer Disease
4Hz Transcranial Alternating Current Stimulation for Patients With Mild Alzheimer's Disease
The goal of this study is to explore the efficacy and safety of 4Hz transcranial alternating current stimulation (tACS) in patients with mild Alzheimer's disease (AD).
- Trial name
- NCT04088643
- Testing
- transcranial alternating current stimulation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xuanwu Hospital, Beijing
Stroke, Carotid Stenosis
Spider Versus Emboshield Distal Protection on Cerebral Microembolization During Vulnerable Plaque in Carotid Artery Stenting
A single center, prospective, outcome-assessor-blinded, randomized controlled trial study (CASH-ES) is designed to compare the efficiency of two different distal embolism protection devices (SpiderFX and Emboshield NAV6) in…
- Conditions
- Stroke, Carotid Stenosis, Carotid Artery Stent
- Trial name
- CASH-ES (NCT04904250)
- Testing
- Emboshield, Spider
- Where
- China
- Volunteers
- 172 people
- Sponsor
- Xuanwu Hospital, Beijing
Acute Ischemic Stroke
Combination of the Immune Modulator Dimethyl Fumarate With Alteplase in Acute Ischemic Stroke
The investigators conduct this study to investigate whether oral administration of Dimethyl Fumarate, a Food and Drug Administration-approved drug for multiple sclerosis, is safe and effective in combination with alteplase in…
- Trial name
- NCT04890366
- Testing
- Dimethyl Fumarate
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xuanwu Hospital, Beijing
Acute Ischemic Stroke
An fNIRS Study of Motor Cortical Activation in Stoke Patients
The investigators evaluate the activation and connectivity of patients' motor regions in the acute phase of ischemic stroke by fNIRS.
- Trial name
- NCT05376098
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xuanwu Hospital, Beijing
Ischemic Stroke
China Angioplasty & Stenting for Symptomatic Intracranial Severe Stenosis
Patients with symptomatic stenosis of intradural arteries are at high risk for subsequent stroke. Since the SAMMPRIS trial, stenting is no longer recommended as primary treatment, however, the results of this trial, its inclusion…
- Trial name
- CASSISS (NCT01763320)
- Testing
- Intracranial stenting group, medical group
- Where
- China
- Volunteers
- 380 people
- Sponsor
- Xuanwu Hospital, Beijing
Alzheimer Disease
A Direct Comparative Study of Tau Tracer in Patients With Alzheimer's Disease
In this study, a total of 60 AD patients with Aβ deposition will beenrolled.Qualified subjects will complete PET imaging scan of Tau imaging agent inXuanwuHospital, and each subject will receive three of the following five…
- Trial name
- HTH (NCT05326009)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xuanwu Hospital, Beijing
Transcranial Magnetic Stimulation, Multiple System Atrophy
TMS Treatment in Multiple System Atrophy With Fatigue
Transcranial magnetic stimulation (TMS) is a procedure that has been shown to improve fatigue in chronic sufferers. It uses a plastic covered coil that sends a magnetic pulse through the skull into the brain and by targeting…
- Conditions
- Transcranial Magnetic Stimulation, Multiple System Atrophy, Fatigue
- Trial name
- TMSMSAF (NCT04313530)
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 22 people
- Sponsor
- Xuanwu Hospital, Beijing
Ischemic Cerebrovascular Disease, Blood Pressure Variability
Blood Pressure Variability in Non-hypertensive Patients With Ischemic Cerebrovascular Disease
This study is a single-center prospective cohort of patients with ischemic cerebrovascular disease (ICVD) who have not met the diagnostic criteria for hypertension.
- Trial name
- BPV-NhICVD (NCT05232240)
- Testing
- blood pressure variability measured by ambulatory 24-hour blood pressure monitoring
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Xuanwu Hospital, Beijing
Alzheimer Disease, Progressive Supranuclear Palsy
Tau Protein and SV2a Imaging in Patients With Tau Protein-related Diseases
Tau protein has been identified as one of the key pathological features of Tau proteinopathies, such as Alzheimer's disease (AD), progressive supranuclear palsy (PSP), frontotemporal dementia (FTD).
- Conditions
- Alzheimer Disease, Progressive Supranuclear Palsy, Frontotemporal Dementia
- Trial name
- NCT05260151
- Where
- China
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Stroke, Adrenal Incidentaloma
Association Between Stroke and Adrenal Incidentalomas
Adrenal incidentalomas (AIs) are commonly encountered in transsection imaging which purpose not for suspected adrenal disease. However, part of AIs in patients is associated with Stroke.
- Trial name
- ABSAI (NCT05237817)
- Where
- China
- Volunteers
- 2 people
- Sponsor
- Xuanwu Hospital, Beijing
Stroke
Multi-delay Arterial Spin Labeling Application in Acute Ischemic Stroke
This study explores the value of the non-invasive quantitative evaluation system for cerebral blood flow perfusion function in the diagnosis of stroke.
- Trial name
- NCT05213793
- Testing
- multi-delay arterial spin labeling
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xuanwu Hospital, Beijing
Acute Ischemic Stroke
XuanwuH Acute Ischemic Stroke Registry
Acute ischemic stroke registry--Xuanwu Hospital(XSR) is an academic, independent, prospective, single center, observational registry study.
- Trial name
- NCT05208203
- Testing
- telephone call d90
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Xuanwu Hospital, Beijing
Motor Function, Gait
Spinal Cord Stimulation Therapy for Hereditary Spastic Paraplegias Patients
It's a single-center, prospective, open label clinical study with a 12 months follow-up period, to investigate the therapeutic effect and safety of spinal cord stimulation (SCS) on motor function and gait in patients with pure…
- Trial name
- NCT05196178
- Testing
- Spinal cord stimulation
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Xuanwu Hospital, Beijing
Coexistence of Cerebral and Coronary Atherosclerosis, Acute Ischemic Cerebrovascular Disease
Coexistence of Cerebral and Coronary Atherosclerosis in Acute Ischemic Cerebrovascular Disease Patients Registry
Coexistence of Cerebral and Coronary Atherosclerosis in Acute Ischemic Cerebrovascular Disease Patients Registry (CoCCA) is a single-center observational registry of patients hospitalized for acute ischemic cerebrovascular…
- Trial name
- CoCCA (NCT03788512)
- Testing
- observational only- no intervention
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Xuanwu Hospital, Beijing
Endometrial Carcinoma
Diagnostic Performance of Hybrid PET/MRI in the Staging of Endometrial Carcinoma
Endometrial carcinoma (EC) is one of the most common gynecologic malignancy in China. EC is staged surgically according to the International Federation of Gynecology and Obstetrics (FIGO) system, including depth of myometrial…
- Trial name
- NCT03945786
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xuanwu Hospital, Beijing
Carotid Artery Occlusion, Middle Cerebral Artery Occlusion
The Carotid and Middle Cerebral Artery Occlusion Surgery Study
The recently published Carotid Occlusion Surgery Study (COSS) failed to show a benefit of extracranial-intracranial (EC-IC) bypass surgery over medical therapy in patients with symptomatic hemodynamically significant carotid…
- Conditions
- Carotid Artery Occlusion, Middle Cerebral Artery Occlusion, Stroke
- Trial name
- CMOSS (NCT01758614)
- Testing
- bypass surgery, Aspirin, Clopidogrel
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Xuanwu Hospital, Beijing
Subarachnoid Hemorrhage, Aneurysmal, Emergency Medical Services
A Registry Study for Emergency Medical Service of Aneurysmal Subarachnoid Hemorrhage in China
This is a staged registry study of early treatment strategy management of acute aneurysmal subarachnoid hemorrhage(aSAH) among different economic development levels areas in China.
- Trial name
- CIAP-5 (NCT03115905)
- Where
- 2 sites in China
- Volunteers
- 6,000 people
- Sponsor
- Xuanwu Hospital, Beijing
Parkinson Disease
Effects of Lingzhi on Disease Progression in Patients With Untreated Early Parkinson's Disease
Lingzhi(Ganoderma) is widely used in traditional Chinese medicine. Previous studies indicated that Lingzhi was safe, well tolorated, and improved symptoms as an add-on therapy to levodopa in early Parkinson's disease(PD)…
- Trial name
- NCT03594656
- Testing
- Ganoderma
- Where
- China
- Volunteers
- 288 people
- Sponsor
- Xuanwu Hospital, Beijing
Premature Ventricular Contraction
Efficacy and Safety of Metoprolol Tartrate Tablets Combined With Chinese Traditional Medicine on Premature Ventricular Complex.
Objective: investigators investigated the effects of metoprolol tartrate plus Tongmai Yangxin Pill on premature ventricular complexes and cardiac function in patients with premature ventricular complex.
- Trial name
- NCT05008250
- Testing
- Tongmai Yangxin Pill (TMYXP), metoprolol tartrate
- Volunteers
- 584 people
- Sponsor
- Xuanwu Hospital, Beijing
Malignant Glioma, Recurrent Glioma
Personalized Vaccine for Patients With Recurrent Malignant Glioma
A single-arm, single-center, open-labeled study will be conducted with an aim to investigate the feasibility, safety, and efficacy of the personalized vaccine for patients with recurrent malignant glioma.
- Trial name
- NCT04943718
- Testing
- personalized vaccine
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Xuanwu Hospital, Beijing