Clinical trials: sponsored by Xuanwu Hospital, Beijing
Postoperative Pain
Preventive Analgesia With Anrikefon in Laparoscopic Cholecystectomy
This study will determine the optimal timing for Anrikefon administration. It will also assess the quality of patient recovery. Laparoscopic cholecystectomy (LC) is a routine surgical procedure.
- Trial name
- ANIPAP (NCT07566663)
- Testing
- Anrikefon for Preventive Analgesia, Anrikefon for bridging analgesia
- Where
- China
- Volunteers
- 274 people
- Sponsor
- Xuanwu Hospital, Beijing
Syringomyelia
Extracellular Vesicles for the Treatment of Syringomyelia
This is a open-label, single-arm, dose escalation phase I clinical trial. The goal of this clinical trial is to evaluate the safety and preliminary efficacy of Intrathecal injection human umbilical cord-derived mesenchymal…
- Trial name
- NCT07295067
- Testing
- Exosomes group
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Xuanwu Hospital, Beijing
Acute Ischemic Stroke, Large Vessel Occlusion
Sivelestat Sodium as an Adjunct to Endovascular Thrombectomy for Acute Anterior Circulation Large-Vessel Occlusion
Stroke remains a major global health burden, with acute ischemic stroke (AIS) accounting for more than 65% of all cases. Endovascular thrombectomy (EVT) has been established as a standard treatment for large vessel occlusion…
- Conditions
- Acute Ischemic Stroke, Large Vessel Occlusion, Thrombectomy, Neutrophil Extracellular Trap Formation
- Trial name
- NCT07552610
- Testing
- Sivelestat sodium, Endovascular Thrombectomy
- Where
- 2 sites in China
- Volunteers
- 868 people
- Sponsor
- Xuanwu Hospital, Beijing
Stroke, Acute Ischemic Stroke
Safety and Efficacy of Adjunctive GM1 to Mechanical Thrombectomy for Acute Anterior Circulation Large Vessel Occlusion
Stroke is a leading cause of global mortality and morbidity, with acute ischemic stroke (AIS) accounting for approximately 65.3% of cases and resulting in roughly 3.4 million new cases annually in China.
- Trial name
- IAT-GIANT (NCT07519044)
- Testing
- Intravenous GM1 Therapy
- Where
- 2 sites in China
- Volunteers
- 868 people
- Sponsor
- Xuanwu Hospital, Beijing
Intracerebral Hemorrhage, Nontraumatic Intracerebral Hemorrhage
CIRP and Cathepsin B in Neuroinflammation After Intracerebral Hemorrhage
This is a single-center, investigator-initiated, prospective observational case-control study. Patients with intracerebral hemorrhage and healthy controls will be enrolled at Xuanwu Hospital, Capital Medical University.
- Trial name
- CIRP-ICH (NCT07665255)
- Testing
- Blood Sample Collection
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Nervous System Diseases, Cerebrovascular Disorders
Efficacy and Safety of Antihypertensive Treatment With Mobile Stroke Units in Ultra-Early Intracerebral Hemorrhage
MSU-ICH is a prospective, multicenter, Week-wise-randomized, open-label, blinded-endpoint (PROBE) clinical trial comparing ultra-early prehospital blood pressure lowering delivered by a Mobile Stroke Unit (MSU) with standard…
- Conditions
- Nervous System Diseases, Cerebrovascular Disorders, Cardiovascular Diseases, Vascular Diseases
- Trial name
- MSU-ICH (NCT07665827)
- Testing
- Mobile Stroke Unit Management, Standard Management
- Where
- China
- Volunteers
- 706 people
- Sponsor
- Xuanwu Hospital, Beijing
Peripheral Arterial Disease, Diabetic Angiopathies
Evaluating Bu Yang Huanwu Decoction For Early Diabetic Vascular Disease
The goal of this clinical trial is to learn if adding a Traditional Chinese Medicine formula, Bu Yang Huanwu Decoction (specifically the capsule form called Hua Yu Wan Capsule), to standard treatment can help prevent leg pain at…
- Conditions
- Peripheral Arterial Disease, Diabetic Angiopathies, Arterial Occlusive Diseases
- Trial name
- NCT07658807
- Testing
- Hua Yu Wan Capsule, Aspirin
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Xuanwu Hospital, Beijing
Intracranial Aneurysm
Real-World Study of Woven EndoBridge for Intracranial Aneurysm Treatment
We designed the Real-World Study of Woven EndoBridge for Intracranial Aneurysm Treatment (WEB-RWS), an ambidirectional, multicenter, post-market real-world study with a prospective active surveillance component.
- Trial name
- WEB-RWS (NCT07620626)
- Testing
- Intrasaccular Flow Disruption Device
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Xuanwu Hospital, Beijing
Alzheimer Disease
Study on the Health Economic Burden of Alzheimer's Disease in China
Alzheimer's disease (AD) presents a significant socio-economic challenge globally, with China experiencing a notable rise in its prevalence.
- Trial name
- NCT05995418
- Testing
- There was no intervention as this was an observational study.
- Where
- China
- Volunteers
- 9,510 people
- Sponsor
- Xuanwu Hospital, Beijing
Intracranial Dural Arteriovenous Fistula
Multicenter Registry Study of Patients With Intracranial Dural Arteriovenous Fistulas in China
This multicenter registry study aims to clarify the incidence trends of intracranial dural arteriovenous fistulas (IDAVF) and spinal dural arteriovenous fistulas (SDAVF) in China, evaluate current treatment patterns, and…
- Trial name
- DREAM (NCT07604688)
- Testing
- endovascular
- Where
- China
- Volunteers
- 10,050 people
- Sponsor
- Xuanwu Hospital, Beijing
PONV, Cerebellopontine Angle Tumor
Oliceridine Versus Sufentanil for Postoperative Nausea in Cerebellopontine Angle Surgery
This single-center, double-blind, randomized controlled trial aims to determine whether oliceridine for patient-controlled intravenous analgesia (PCIA) can significantly reduce the incidence of postoperative nausea, an…
- Conditions
- PONV, Cerebellopontine Angle Tumor, Microvascular Decompression Surgery, Postoperative Analgesia
- Trial name
- NCT07479446
- Testing
- Oliceridine, Sufentanil
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Xuanwu Hospital, Beijing
Fistula
Dural Arteriovenous Fistulas Research at China INI
Dural arteriovenous fistula (DAVF) refers to abnormal connections between meningeal arteries and dural venous sinuses and/or subarachnoid veins. DAVF accounts for approximately 10% to 15% of intracranial vascular malformations.
- Trial name
- NCT06543472
- Where
- China
- Volunteers
- 1,180 people
- Sponsor
- Xuanwu Hospital, Beijing
Mild to Moderate Alzheimer's Disease
The Effect of CB-Exo-A600 in Mild to Moderate Alzheimer's Disease
This study is divided into two phases: a dose-escalation phase and an expansion cohort phase. The dose-escalation phase is a single-center study, while the expansion cohort phase is a multicenter, prospective, randomized…
- Trial name
- CB-EXOAD (NCT07457125)
- Testing
- Exosomes derived from umbilical cord mesenchymal stem cell for intranasal drop
- Where
- China
- Volunteers
- 33 people
- Sponsor
- Xuanwu Hospital, Beijing
CDKL5 Deficiency Disorder
Efficacy and Safety of Daily Home-based Hyperthermic Baths for Reducing Epileptic Seizures in CDKL5 Deficiency Disorder: A PROBE Clinical Trial
The primary objective of this research is to study the efficacy and safety of daily, home-based hyperthermic baths for reducing epileptic seizures in CDKL5 Deficiency Disorder.
- Trial name
- NCT07602205
- Testing
- Home-based hyperthermic Baths
- Volunteers
- 34 people
- Sponsor
- Xuanwu Hospital, Beijing
Super-refractory Status Epilepticus
KD Treatment for Super-refractory Status Epilepticus
The purpose of the study is to investigate to evaluate the efficacy and safety of ketogenic diet (KD) as an adjunctive therapy in patients with Super Refractory Status Epilepticus (SRSE) in the intensive care unit (ICU).
- Trial name
- KD (NCT07496749)
- Testing
- the ketogenic diet, Standard Medical Therapy
- Where
- 14 sites in China
- Volunteers
- 84 people
- Sponsor
- Xuanwu Hospital, Beijing
Essential Hypertension
Safety and Efficacy Evaluation of Non-invasive Temporal Interference Stimulation for Blood Pressure Modulation in Patients With Mild Essential Hypertension
The primary objective of this research is to study the efficacy and safety of temporal interference stimulation for blood pressure modulation in patients with mild essential hypertension.
- Trial name
- NCT07577323
- Testing
- Temporal Interference
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xuanwu Hospital, Beijing
Primary Hypertension
High-Intensity Transcranial Alternating Current Stimulation (Hi-tACS) for Hypertension: A Randomized Controlled Trial
This study focuses on individuals with primary hypertension, with the main objective of investigating the effectiveness and safety of high-intensity transcranial alternating current stimulation (Hi-tACS) as a non-invasive…
- Trial name
- NCT07566650
- Testing
- Active High-Intensity Transcranial Alternating Current Stimulation (Hi-tACS)
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xuanwu Hospital, Beijing
Cerebral Ischemia, PET / MR
Research on the Application of Sigma Radiopharmaceutical FBFP in Cerebral Stroke
This clinical research, aims to investigate the uptake of [18F]FBFP, a Sigma-1 receptor (Sig 1R) PET imaging agent, in stroke participants, compare differences with healthy controls, and evaluate its diagnostic efficacy…
- Trial name
- NCT07558577
- Testing
- PET/MR multimodality imaging
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Neuroimmune Diseases With Insomnia
Study on the Clinical Efficacy of Transcranial Strong Alternating Current (Hi-tACS) in Patients With Neuroimmune Diseases With Insomnia
This study aims to comprehensively evaluate the therapeutic effects of high-intensity transcranial alternating current stimulation (hi-tACS) on insomnia symptoms in patients with idiopathic inflammatory demyelinating disorders…
- Trial name
- NCT07558616
- Testing
- high-intensity transcranial alternating current stimulation, hi-tACS
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Xuanwu Hospital, Beijing
Neuromyelitis Optica
An Open Label Study of the Effects and Safety of Zanubrutinib in NMOSDs Adult Patients
This is an open-label study, to evaluate the efficacy and safety of a BTK inhibitor zanubrutinib in participants with NMOSDs.
- Trial name
- NCT05356858
- Testing
- zanubrutinib
- Where
- China
- Volunteers
- 6 people
- Sponsor
- Xuanwu Hospital, Beijing