Clinical trials: sponsored by Zagazig University
Wrinkle
Threads Insertion in Forehead Static Wrinkles
The main objective of this study is to analyze the efficacy and safety of PDO threads in correcting deep static wrinkles on the upper face.
- Trial name
- NCT06179082
- Testing
- Botox then threads, threads only
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Zagazig University
Analgesia
Ultrasound-Guided Intermediate Cervical Plexus or Cervical Erector Spinae Block for Anterior Cervical Spine Surgery
Neck pain and stiffness or sore throat, are common after anterior cervical spine surgery. Complications are rare but can be serious and even potentially life-threatening if they do occur.
- Trial name
- NCT05577559
- Testing
- intermediate cervical plexus block, Cervical Erector spinae block
- Where
- Egypt
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Incisional Hernia, Onlay Mesh
Incisional Hernia Repair by Abdominal Wall Component Release With Contemporary Onlay Mesh Fixation
There is a great expansion in the presentation of complex incisional hernia defects. Primary closure for most cases is impossible with a high rate of recurrence.
- Conditions
- Incisional Hernia, Onlay Mesh, Abdominal Wall Component Release
- Trial name
- NCT06178965
- Testing
- Incisional Hernia Repair by Abdominal Wall Component Release with Contemporary Onlay Mesh Fixation
- Where
- Egypt
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Zagazig University
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
Insulin Sensitizers Role in Control of PCOS Vicious Cycle.
PCOS is a common and complex disease affecting women of reproductive age. It is characterized by its complex pathological symptoms and mechanisms resulting in endocrine and metabolic dysfunction.
- Trial name
- NCT06170463
- Testing
- Metformin Hydrochloride, MI/DCI combination in 40:1 ratio, Combination of Metformin hydrochloride and MI/DCI
- Where
- Egypt
- Volunteers
- 210 people
- Sponsor
- Zagazig University
Trauma
The Relation Between Quadriceps Muscle Layer Thickness and Nitrogen Balance for Nutrition Monitoring
Loss of muscle mass is a major cause of intensive care unit-acquired weakness (ICU-AW) and is associated with delayed weaning; prolonged ICU and hospital stay and is an independent predictor of one year mortality.
- Trial name
- NCT04303650
- Testing
- Ultrasound measurement of quadriceps muscle layer thickness
- Where
- Egypt
- Volunteers
- 186 people
- Sponsor
- Zagazig University
Endometrial Cancer
Immunohistochemistry Role in Better Prognosis of Endometrial Carcinoma Patients
The incidence of endometrial cancer (EC) is increasing .Different risk classifications are used to direct the primary and adjuvant therapy.
- Trial name
- NCT06148129
- Testing
- Tissue Biopsy
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Zagazig University
Diagnoses Disease
Immunoblot, Chemiluminescence and ImmunoCap Allergen Specific IgE Evaluation of in Allergic Rhinitis Patients
In the present study the investigators assay house dust mites (HDMs) IgE in sera of allergic rhinitis patients (AR) using immunoblotting, chemiluminescence, and ImmunoCAP assays to compare between the accuracy of both…
- Trial name
- NCT06137495
- Testing
- Sensitization to House dust mites
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Zagazig University
Anesthesia, ERAS
Goal-Directed Fluid Therapy in Patients Undergoing Lower Limb Surgeries
Controlling the amount of fluids given to patients in perioperative setting can significantly influence their outcomes.
- Conditions
- Anesthesia, ERAS, Fluid Overload, Hypovolemia; Surgical Shock
- Trial name
- NCT06133257
- Testing
- Goal-Directed Fluid Therapy guided by Inferior Vena Cava Collapsibility Index, standard fluid management
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Rheumatoid Arthritis (RA) and Osteoarthritis (OA)
Serum IL-17 Correlated With Inflammatory Changes in Osteoarthritis and Rheumatoid Arthritis
The total number of the included subjects was 120 in 3 equal groups (RA, OA and control). All subject was subjected to serum IL17 level measurement.
- Trial name
- NCT04474912
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Analgesia
Management of Post Dural Pucture Headache After Lower Limb Surgeries: Oral Prednisolone vs Oral Pregabalin
The aim of this study is to compare between oral prednisolone and oral pregabalin in management of PDPH to detect effectiveness of the treatment in reducing severity of PDPH, total rescue analgesic consumption and adverse effects…
- Trial name
- NCT04662125
- Testing
- caffeine, paracetamol tablet, Oral prednisolone, oral pregabalin
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Conscious Sedation
Monitored Anesthesia Care: Dexmedetomidine-Ketamine Versus Dexmedetomidine- Propofol For Chronic Subdural Hematoma
Inadequate sedation and analgesia indicated by intraoperative movements are markers of inadequate MAC during burr-hole surgery for chronic subdural hematoma evacuation especially when general anesthesia poses high risk for the…
- Trial name
- NCT04621526
- Testing
- dexmedetomidine- ketamine, dexmedetomidine- propofol
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Thyroid Diseases
Topical Bupivacaine Effect On The Response To Awake Extubation During Emergence From General Anesthesia
Emergence from general anesthesia is often complicated by the ETT-induced emergence phenomena (EP), which include coughing, sympathetic stimulation, sore throat, increased bleeding from the surgical site, and increased…
- Trial name
- NCT04471597
- Testing
- normal saline 0.9%, Bupivacaine Hydrochloride
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Zagazig University
ICU Acquired Weakness
Evaluation of Diaphragmatic Function and Quadriceps Muscle Thickness in Patients Receiving High Protein Nutrition
Different Protein Doses' Effect on Diaphragmatic Function and Quadriceps Thickness
- Trial name
- NCT06025760
- Testing
- patients who will receive 2 gm protein/kg/day will be evaluated by ultrasound for diaphragmatic function and quadriceps muscle thickness
- Volunteers
- 32 people
- Sponsor
- Zagazig University
Post Spinal Anesthesia Shivering
Clonidine Versus Granisetron for Shivering Prevension
Prevention of post spinal anesthesia shivering during cesarean section with its associated discomfort, distress, aggravation of pain, increased metabolic demands, and increased oxygen consumption
- Trial name
- NCT06031090
- Testing
- Clonidine Injection, Granisetron Injection, Normal Saline 10 mL Injection
- Where
- Egypt
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Postoperative Pain
Rhomboid Intercostal Block Versus Serratus Anterior Plane Block
evaluate and compare the impact of ultrasound guided rhomboid intercostal block versus serratus anterior plane block for analgesia after thoracodorsal artery perforator flap following partial mastectomy
- Trial name
- NCT05661279
- Testing
- general anesthesia, general anesthesia plus Rhomboid intercostal block, Serratus anterior plane block
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Leishmaniasis, Cutaneous
Intralesional Voriconazole, or Intralesional Cryotherapy, or Oral Doxycycline in the Treatment of Cutaneous Leishmaniasis
Leishmaniasis is a vector-borne disease caused by obligate, intracellular protozoa of the genus Leishmania and transmitted by phlebotomine sandflies.
- Trial name
- NCT05708625
- Testing
- Intralesional Sodium stibogluconate, Intralesional Cryotherapy, Intralesional Voriconazole
- Where
- Libya
- Volunteers
- 136 people
- Sponsor
- Zagazig University
Postoperative Pain, Acute
Modified Versus Conventional Serratus Anterior Plane Block
comparing preemptive analgesia with ultrasound guided modified serratus anterior plane block versus ultrasound guided serratus anterior plane block
- Trial name
- NCT05661253
- Testing
- 25 ml of bupivacaine 0.25% via serratus anterior block, 25 ml of bupivacaine 0.25% via modified serratus anterior palne block
- Where
- Egypt
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Postoperative Recovery, Epidural Blockade
Enhanced Recovery After Lumber Laminectomy Using Epidural and General Anesthesia
Now, enhanced recovery after surgery (ERAS) is considered an essential goal to improve patient satisfaction, increase surgical workflow rate and facilitate performing different surgical procedures, including lumber laminectomy…
- Conditions
- Postoperative Recovery, Epidural Blockade, Endotracheal Tube, Laminectomy
- Trial name
- NCT04981158
- Testing
- (Epidural /GA using tolerable endotracheal tube (TET) group, group II, standard general anesthetic technique, control group, group I
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Zagazig University
Delirium on Emergence
Ketofol for Preventing Postoperative Delirium in Elderly Patients
Delirium is a cognitive disturbance characterized by acute and fluctuating impairment in attention and awareness. Although its incidence in the general surgical population is 2-3%, it has been reported to occur in up to 10-80% of…
- Trial name
- NCT04816162
- Testing
- ketofol, dexmedetomidine, normal saline
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Zagazig University
Intraocular Foreign Body
Extraction Routes of Intraocular Foreign Body
Intra ocular foreign body removal is indicated to avoid further many complications such as retinal detachment, endophthalmitis. The surgical approach for a posterior segment IOFB is pars plana vitrectomy and its extraction either…
- Trial name
- IOFB (NCT05966545)
- Testing
- pars plana vitrectomy and intraocular foreign body removal
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Zagazig University