Clinical trials: sponsored by Zagazig University
Dry Eye
20-20-20 Rule Plus Artificial Tears for Dry Eye
This study is for anyone struggling with dry, tired, or uncomfortable eyes, especially from long hours on screens. We all know that feeling after staring at a laptop or phone too long.
- Trial name
- NCT07896395
- Testing
- Artificial Tears (AT), 20/20/20 rule
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Zagazig University
Craniotomy Surgery
Sphenopalatine Ganglion Block Combined With Either Scalp Nerve Block or Local Wound Infiltration for Postoperative Analgesia in Adult Patients Undergoing Craniotomy: A Randomized Controlled Trial
The use of multimodal regional analgesia (scalp block, local scalp infiltration, and sphenopalatine ganglion block) for postoperative pain management after craniotomy
- Trial name
- NCT07886034
- Testing
- Group (c): control group patients will receive general anesthesia., Group (SS): Sphenopalatine Ganglion Block with either Scalp Nerve Block, Group (SL): patients will receive Sphenopalatine Ganglion Block with local wound infiltration
- Volunteers
- 54 people
- Sponsor
- Zagazig University
Postoperative Pain After Spinal Surgery
Modified Thoracolumbar Interfascial Plane Block vs Retrolaminar Block for Pain in Lumbar Spine Surgeries
This prospective randomized double-blind study aims to compare the efficacy of modified Thoracolumbar Interfascial Plane (mTLIP) block versus Retrolaminar block for postoperative pain control in patients undergoing elective…
- Trial name
- NCT07883616
- Testing
- Morphine, Bupivacaine, Dexamethasone
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Zagazig University
Buccal Mucosal Defect
The Role of Amniotic Membrane in Promoting Rapid Recovery of Buccal Mucosal Defect After Harvesting Oral Mucosa for Urethral Reconstruction
investigators use biological material to enhance recovery of oral cavity row area after harvesting a graft from it to use it in urethral reconstruction
- Trial name
- NCT07824596
- Testing
- use of amniotic membrane as a biological dressing over buccal mucosal raw area
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Zagazig University
Difficult Intubation, Obesity
Modified El-Ganzouri Risk Index for Predicting Difficult Intubation in Obese Patients
This observational study aims to compare the predictive performance of the Modified El-Ganzouri Risk Index (MEGRI) incorporating anthropometric ratios with the original El-Ganzouri Risk Index (EGRI) for predicting difficult…
- Trial name
- MEGRI (NCT07857395)
- Testing
- No intervention
- Where
- Egypt
- Volunteers
- 114 people
- Sponsor
- Zagazig University
HELICOBACTER PYLORI INFECTIONS
Lignin in Treatment of Helicobacter Pylori Infection
The goal of this clinical trial is to learn if drug hydrolyzed lignin works to treat H pylori infection in adults. It will also learn about the safety of drug lignin n the sitting of H pylori infection, and if it halts the side…
- Trial name
- NCT07246681
- Testing
- Hydrolyzed Lignin
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Zagazig University
Lumbar Spine Fixation
Fentanyl as Adjuvants to Epidural Bupivacaine Plus Dexamethasone for Analgesia
The purpose of this study is to compare better postoperative analgesia after lumbar spine Fixation using either epidural bupivacaine with midazolam or fentanyl with the combination of dexamethasone.
- Trial name
- NCT06898697
- Testing
- postoperative analgesia, epidural fentanyl
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Zagazig University
Opioid Free Anesthesia, Opioid Based Anesthesia
Intraoperative Infusion of Dexmedetomidine Versus Lidocaine or Magnesium Sulphate for Enhanced Quality of Recovery After Spine Surgery Fixation
Thoracolumbar fixation is a major spine surgery; it is performed to stabilize the spine after trauma, deformity or advanced degenerative disease.
- Conditions
- Opioid Free Anesthesia, Opioid Based Anesthesia, Spine Fixation Surgeries, Opiod-Related Disorders
- Trial name
- NCT07843953
- Testing
- Group ( L): LICOCAINE, GROUP Dexmedetomidine, Group M: Magnesium sulphate
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Chronic Knee Pain, Osteoarthritis
Sequential Genicular Nerve Ablation Prior to Geniculate Artery Embolization in Knee Pain
The goal of this clinical trial is to evaluate whether performing genicular nerve ablation (GNA) before geniculate artery embolization (GAE) improves pain relief and knee function in patients with chronic knee pain.
- Trial name
- NCT06514755
- Testing
- GNA followed by GAE, GAE alone
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Zagazig University
Mechanical Ventilation Complication, Ventilator Induced Lung Injury
Mechanical Power and Mortality in Mechanically Ventilated Adults
This prospective observational cohort study aims to investigate the relationship between mechanical power during the first 72 hours of invasive mechanical ventilation and 28-day mortality in mechanically ventilated adult patients…
- Conditions
- Mechanical Ventilation Complication, Ventilator Induced Lung Injury, ARDS, ICU Mortality (Survival Rate)
- Trial name
- NCT07836153
- Where
- Egypt
- Volunteers
- 116 people
- Sponsor
- Zagazig University
Osteoarthritis, Knee
Comparative Study of CT and Fluoroscopic Guided Genicular Nerve Ablation in the Treatment of Knee Osteoarthritis
The goal of this study is to evaluate the comparative effectiveness of CT-guided and fluoroscopic-guided genicular nerve ablation in reducing knee pain and improving function in adults diagnosed with knee osteoarthritis…
- Trial name
- NCT06514703
- Testing
- CT-Guided Genicular Nerve Ablation, Fluoroscopic-Guided Genicular Nerve Ablation
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Zagazig University
Trigeminal Neuralgia, Trigeminal Neuralgia, Idiopathic
CT-guided vs Fluoroscopy-guided Trigeminal Ganglion Radiofrequency Thermocoagulation for Idiopathic Trigeminal Neuralgia
The goal of this clinical trial is to compare the effectiveness and safety of CT-guided versus fluoroscopy-guided trigeminal ganglion radiofrequency thermocoagulation (TG-RFT) in treating idiopathic trigeminal neuralgia (TN) in…
- Trial name
- NCT06620172
- Testing
- CT-guided Radiofrequency Thermocoagulation (RFT), Fluoroscopy-guided Radiofrequency Thermocoagulation (RFT)
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Zagazig University
Non-diabetec Obesity, Obesity (Disorder)
Weekly GLP-1 Receptor Agonists in Obese Individuals Without Diabetes
This randomized controlled trial evaluates the efficacy of three weekly GLP-1 receptor agonists (dulaglutide, semaglutide, and tirzepatide) in non-diabetic obese adults.
- Trial name
- NCT07834398
- Testing
- Dulaglutide, Semagludtide, Tirzepatide
- Where
- Saudi Arabia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Primary Congenital Glaucoma
Combined Nasal Goniotomy-Temporal Trabeculotomy Versus Temporal Trabeculotomy for Management of Primary Congenital Glaucoma
Combined nasal goniotomy and temporal trabeculotomy provides effective IOP control in PCG while preserving the superior conjunctiva for future filtering procedures.
- Trial name
- NCT07830017
- Testing
- combined Nasal goniotomy-Temporal trabeculotomy, Temporal trabeculotomy
- Where
- Egypt
- Volunteers
- 21 people
- Sponsor
- Zagazig University
Atrophic Acne Scarring
Poly-L-Lactic Acid in Atrophic Acne Scars
Background: Management of atrophic acne scars remains challenging due to their heterogeneous morphology and suboptimal response to conventional therapies.
- Trial name
- NCT07523217
- Testing
- injectable PLLA, PLLA threads
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Post Operative Pain, Preemptive Analgesia
Paracetamol Plus Tramadol Versus Fentanyl in Day Case Surgeries
Postoperative pain is an important problem, especially for day case surgeries. It has negative effects on patient's hemodynamics and can cause delayed ambulation resulting in prolonged duration of hospital stay and poor patient…
- Trial name
- NCT05990686
- Testing
- tramadol plus paracetamol, Fentanyl Injection
- Where
- Egypt
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Obese Diabetics, Obese Non Diabetic
Comparative Study of Different Weekly GLP-1 Receptor Agonists Among Diabetic and Non-Diabetic Patients: Clinical Trial
titel : Comparative Study of Different Weekly GLP-1 Receptor Agonists Among Diabetic and Non-Diabetic Patients: Clinical Trial Abstract : Background: This study that highlights the different effects of most used three GLP-RA…
- Trial name
- NCT07820111
- Testing
- Dulaglutide 1.5 MG/ML, Semaglutide 2 mg/1.5 ml (1.34 mg/ml), prefilled pen-injector for subcutaneous injection solution, Tirzepatide is administered as part of routine clinical care for obesity management, according to standard prescribing practices. Dosing and treatment duration are determined by the treating physician
- Where
- Saudi Arabia
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Post Cardiac Surgery Atrial Fibrillation
The Outcomes of Sympathetic Cardiac Denervation on Postoperative Atrial Fibrillation After Cardiac Surgery, Randomized Controlled Trial
we compare the effect of cutting heart nerves in one group of patients with open heart surgery and other group without cutting oh development of disturbance of heart beat after surgery
- Trial name
- NCT07811817
- Testing
- cardiac sympathetic denervation, Standard open-heart surgery without additional epicardial or fat pad dissection.
- Where
- Egypt
- Volunteers
- 560 people
- Sponsor
- Zagazig University
Post Hysterectomy Pain
Ultrasound Guided QLB Versus Laparoscopic Superior Hypogastric Plexus Block for Postoperative Analgesia After Laparoscopic Hysterectomy
Pain following laparoscopic hysterectomy may interfere with early ambulation, discharge of patient from hospital and interfere with enhanced recovery with more opioid consumption.
- Trial name
- NCT06359743
- Testing
- Quadratus Lamborum versus superior hypogatric
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Zagazig University
Sleep Apnea Syndromes
f Adding Ketamine to Propofol For Drug-induced Sleep Endoscopy in Adult Patients With Obstructive Sleep Apnea
The investigator compared the sedative effects of propofol alone and ketamine added to propofol in drug induced sleep endoscopy
- Trial name
- NCT04452383
- Testing
- Ketamine + propofol, propofol
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Zagazig University