Clinical trials: sponsored by Zagazig University
Intraocular Foreign Body
Extraction Routes of Intraocular Foreign Body
Intra ocular foreign body removal is indicated to avoid further many complications such as retinal detachment, endophthalmitis. The surgical approach for a posterior segment IOFB is pars plana vitrectomy and its extraction either…
- Trial name
- IOFB (NCT05966545)
- Testing
- pars plana vitrectomy and intraocular foreign body removal
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Effects of; Anesthesia, Local,Pain,in DISE
Anesthetic Approaches for Dacryocystorhinostomy Surgery: The Effect of Adding Local Anesthesia to General Inhalational Anesthesia
To Study the effect of combination of of general anesthesia and local anesthesia in anesthesia for external dacryocystorhinostomy and assess quality of the procedure
- Trial name
- NCT04300595
- Testing
- Combination of General anesthesia and local anesthesia in dacryocystorhinostomy surgery
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Zagazig University
Premature Birth, NEUROPROTECTION
Magnesium Sulphate Neuroprotective Strategies for Preterm Deliveries
A Cochrane systematic review has confirmed that fetal exposure to magnesium sulphate given before preterm birth has a neuroprotective role.
- Conditions
- Premature Birth, NEUROPROTECTION, MAGNESIUM SULPHATE, Cerebral Palsy
- Trial name
- NCT05674565
- Testing
- Magnesium sulfate loading with maintenance dose, Magnesium sulfate loading dose only
- Where
- Egypt
- Volunteers
- 336 people
- Sponsor
- Zagazig University
Pediatric Postoperative Pain
Ultrasound Guided Pericapsular Nerve Group Block Versus Quadratus Lumborum Block
Hip surgeries in pediatrics consider as one of the common nowadays surgeries with sever postoperative pain so pain management is essential to decrease postoperative complications, early mobilization and hospital discharge.
- Trial name
- NCT05444309
- Testing
- Quadratus lumborum (QL) block group, Pericapsular Nerve Group (PENG) block group
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Zagazig University
Preterm Birth, Twin Pregnancy, Antepartum Condition or Complication
Prophylactic Cervical Cerclage in Twin Pregnancies With Non-shortened Cervix
This randomized controlled trial is aimed to assess the protective value of prophylactic cervical cerclage against preterm birth in twin pregnancies with history of one or more preterm births without having cervical shortening in…
- Conditions
- Preterm Birth, Twin Pregnancy, Antepartum Condition or Complication, Cervical Cerclage
- Trial name
- NCT05334264
- Testing
- Cervical cerclage
- Where
- Egypt
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Postoperative Pain
Erector Spinae Plane Block Versus Oblique Subcostal Transverses Abdominis Plane Block
Comparing the impact of bilateral erector spinae plane block and transverse abdominis plane block on improving quality of pain management after umbilical hernia repair.
- Trial name
- NCT05286125
- Testing
- erector spinae plane (ESP) block, oblique subcostal transverse abdominis plane (TAP) block
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zagazig University
PCOS
Progesterone-Primed Ovarian Simulation in Controlled-ovarian Simulation of Infertile PCOS Patients
The study evaluated the safety and efficacy of the progesterone-primed ovarian stimulation (PPOS) coupled with gonadotropin (FSH) for infertile women with polycystic ovary syndrome (PCOS) who were assigned for ICSI and frozen…
- Trial name
- NCT05939284
- Testing
- Injection of Cetrorelix, Oral insertion of dydrogeserone
- Where
- Egypt
- Volunteers
- 238 people
- Sponsor
- Zagazig University
Bipolar Depression
Intensive Accelerated Theta Burst Stimulation in Treatment of Patients With Bipolar Depression and Suicidality
The objective of this study is to compare the efficacy of left unilateral versus bilateral accelerated Theta Burst Stimulation (TBS) in suicidal reduction and in reduction of severity of depressive symptoms in patients with…
- Trial name
- NCT05939115
- Testing
- Transcranial Magnetic Stimulation MagPro R30 with the MCF-B70 figure-of-eight coil (MagVenture, Denmark)
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Zagazig University
GERD
Intraoperative Endomanometric Laparoscopic Nissen Fundoplication Improves Postoperative Outcomes
Laparoscopic Nissen fundoplication (LNF) is a surgical intervention for gastroesophageal reflux disease (GERD); however, it can be followed by recurrent symptoms or complications that may affect patient satisfaction.
- Trial name
- NCT05851794
- Testing
- endomanometric guided LNF, laparoscopic Nissen fundoplication alone
- Volunteers
- 360 people
- Sponsor
- Zagazig University
Liver Surgery
Biliary Fistula and Late Recurrence of Liver Hydatid Cyst: Role of Cysto-biliary Communication
Purpose : The primary goals of this study were to determine the prevalence and risk factors of occult CBC and recurrence, as well as the relationship between occult cysto-biliary communications manifested as postoperative biliary…
- Trial name
- NCT05116735
- Testing
- laparoscopic partial cystectomy with omentoplasty
- Volunteers
- 244 people
- Sponsor
- Zagazig University
of Lung Ultrasound in Diagnosis of Acute Respiratory Distress Syndrome
Validity of Lung Ultrasound in Diagnosis of Acute Respiratory Distress Syndrome
To evaluate the validity of lung ultrasound compared to CT chest and chest radiograph for diagnosis of ARDS and prediction of successful weaning from mechanical ventilation in those patients compared to traditional methods.
- Trial name
- NCT05886556
- Where
- Egypt
- Volunteers
- 57 people
- Sponsor
- Zagazig University
Pericapsular Nerve Group Block (PENG Block), Lumbar Erector Spinae Plane Block
Pericapsular Nerve Group (PENG) Block Versus Lumbar Erector Spinae Plane Block
assess and compare the efficacy of pericapsular nerve group block wersus lumber erector spinae plane block in reducing postoperative pain within the first 24 hours after hip surgeries.
- Trial name
- NCT04899388
- Testing
- Pericapsular Nerve Block, Lumbar Erector Spinae Plane Block, Fentanyl
- Where
- Egypt
- Volunteers
- 69 people
- Sponsor
- Zagazig University
Rectal Prolapse
LVMR Versus PSR for External FTRPin Elderly Patients
In frail patients with external full-thickness rectal prolapse (FTRP), the exact postoperative recurrence and functional result outcomes difference between Laparoscopic ventral mesh rectopexy (LVMR) and perineal stapler resection…
- Trial name
- NCT05915936
- Testing
- LVMR, PSR
- Volunteers
- 330 people
- Sponsor
- Zagazig University
Mucormycosis; Rhinocerebral (Etiology), Post COVID-19 Condition, Unspecified
Post-COVID-19 Mucormycosis in Critical Care
Background: Mucormycosis is a life-threatening opportunistic fungal infection. Despite mucormycosis having existed for decades, it has gained notice of its widespread in many parts of the world during the second wave of the…
- Trial name
- NCT05911035
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Zagazig University
Melasma
Tranexamic Acid With Microneedling in Melasma
Topical tranexamic, a hydrophilic molecule, can't pass the lipid barriers of the stratum corneum and it's also not retained in adequate amount in the epidermis to enter the melanocytes, so there's a difficulty in the effective…
- Trial name
- NCT05909072
- Testing
- Hyaluronic acid combined with tranexamic acid microneedling, tranexamic acid microneedling
- Volunteers
- 27 people
- Sponsor
- Zagazig University
Traumatic Brain Injury
Role of Combined Therapy of Propranolol and Gabapentin in Paroxysmal Sympathetic Hyperactivity in Traumatic Brain Injury
Paroxysmal sympathetic hyperactivity (PSH) is a syndrome that comprises a series of signs and symptoms reflecting exacerbated sympathetic activity, including arterial hypertension, fever, tachycardia, generalized perspiration…
- Trial name
- NCT05427474
- Testing
- Propranolol , gabapentin
- Where
- 2 sites in Egypt
- Volunteers
- 90 people
- Sponsor
- Zagazig University
Lower Limb Surgeries
Epidural Nalbuphine Versus Dexmedetomidine as Adjuvants to Bupivacaine in Lower Limb Surgeries
Combined spinal epidural anesthesia (CSE) with bupivacaine alone is not sufficient to cover pain sequel during lower limb surgeries.
- Trial name
- NCT05041270
- Testing
- normal saline, Dexmedetomidine, Nalbuphine
- Where
- Egypt
- Volunteers
- 23 people
- Sponsor
- Zagazig University
Infertility
Frozen Embryo Transfer in PCOS Patients
Polycystic ovarian syndrome (PCOS) is condition characterized by being complex, familial and polygenetic metabolic condition with heterogeneous involvement of several genes in the hypothalamic-pituitary-gonadal axis.
- Trial name
- NCT05854810
- Testing
- fertilized embryo Insertion
- Where
- Egypt
- Volunteers
- 271 people
- Sponsor
- Zagazig University
Analgesia Post Craniotomy
Opioid-Sparing Multimodal Analgesia Versus Opioid Analgesia for Postoperative Pain After Elective Craniotomy
Several neurosurgical procedures can cause postoperative pain including craniotomies for tumor resections, epilepsy surgery and craniotomies for aneurysm clipping, penetrating traumatic brain injury, and neuroradiological…
- Trial name
- NCT05474040
- Testing
- Morphine versus multimodal analgesia for post elective craniotomy pain
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Intracranial Pressure Changes
Impact of Low Dose Ketamine Infusion in Septic Patient on Non-invasive Estimators of ICP
Severe sepsis is a major healthcare problem with a reported incidence of 1-2% in all hospitalizations. It is a major cause of death in the intensive care units worldwide and is the second leading cause of death in noncoronary…
- Trial name
- NCT05149586
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Zagazig University