Clinical trials: sponsored by Zagazig University
Colonic Fistula
Endoscopic Management Of Low Output Recurrent Colonic Fistula Or Leak After Anterior Resection For Rectal Cancer
This prospective randomized controlled clinical trial included all patients who developed the manifestations of low output recurrent colonic fistula or leak after colonic anterior resection for rectal cancer at Zagazig University…
- Trial name
- NCT05659446
- Testing
- endoscopy management of low output colonic fistula or leak after anterior resection for rectal cancer
- Where
- Egypt
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Effects of Immunotherapy
Serum MicroRNAs 223 and 146a in Allergic Rhinitis Patients as Biomarkers for Efficacy of Sublingual Immunotherapy
The aim of the study is: to evaluate the serum levels of miR-223 and miRNA146a and to assess their correlation with disease severity in allergic rhinitis patients and their role as biomarkers for efficacy of sublingual…
- Trial name
- NCT04813380
- Testing
- Sublingual immunotherapy
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Zagazig University
Opioid Free Anesthesia
Intraoperative Retrolaminar Block as Opioid Free Anesthesia After Posterior Lumber Spine Discectomy
Opioid-free intraoperative protocols have been successfully used in specific surgical populations with equal or superior results to classic general anesthetic approaches.
- Trial name
- NCT05312866
- Testing
- Standard analgesia (paracetamol +fentanyl), Retrolaminar block with bupivacaine + magnesium sulfate + dexamethasone
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Cervical Spine Surgery
Analgesic Efficacy of the Novel Intra- Semispinal Fascial Plane Block in Posterior Cervical Spine Surgery
Posterior cervical spine surgery often requires a large posterior midline incision, resulting in poorly controlled postoperative pain, which arises from iatrogenic mechanical damage, intraoperative retraction, and resection to…
- Trial name
- NCT04974658
- Testing
- Inter-semispinal plane block
- Where
- 2 sites in Egypt
- Volunteers
- 52 people
- Sponsor
- Zagazig University
Elderly Patient Withsigmoid Volvulus
Endoscopic Management of Acute Sigmoid Volvulus in High Risk Surgical Eldery Patients: A Randomized Controlled Trial.
This prospective randomized controlled clinical trial included all patients who developed the manifestations of acute a cute sigmoid volvulus and referred to the Zagazig University Hospital Emergency Department between December…
- Trial name
- NCT05620446
- Testing
- endoscopy
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Zagazig University
Satisfaction
Surgeons' Satisfaction With the Surgical Training Program in Egypt
In Egypt, the evidence for quality processes has not been established yet in the current training programs for surgery residents. There are no published articles discussing career satisfaction among surgical residents.
- Trial name
- multi-center (NCT03142308)
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Magnesium Sulfate, Labetalol
Evaluation of Intravenous Infusion of Labetalol Versus Magnesium Sulfate
the purpose of this study is to compare Intravenous infusion of Labetalol versus Magnesium Sulfate on Cerebral Hemodynamics of Severe Preeclampsia Patients using Transcranial Doppler
- Trial name
- NCT04539379
- Testing
- Magnesium sulfate, Labetolol
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Bleeding
Nasal Desmopressin Versus Oral Bisoprolol for Controlling Bleeding During Endoscopic Sinus Surgery
Functional endoscopic sinus surgery (FESS) is well established for treatment of chronic rhinosinusitis and nasal polyps. Masking of the surgical field can lead to severe complication as tissue injury, increase post-operative…
- Trial name
- NCT05430048
- Testing
- nasal Desmopressin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Zagazig University
Renal Failure, Hepatic Failure
The Role of Skin Microbiota in Hepatic or Renal Pruritus
Various neurotransmitters may share in the pathogenesis of hepatic and renal itching. Skin microbiota may share in the pathogenesis of pruritus.
- Conditions
- Renal Failure, Hepatic Failure, Pruritus
- Trial name
- NCT05604469
- Testing
- Isolation of skin microbiota
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Breast Cancer Radiotherapy
Accelerated Hypofractionated 1 Week Radiotherapy in Breast Cancer Patients
Accelerated hypofractionated 1 week post-mastectomy chest wall irradiation in breast cancer patients will presumably produce comparable toxicity and disease control in comparison to 3 weeks schedule.
- Trial name
- NCT05591456
- Testing
- adjuvant radiotherapy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Zagazig University
Hernia, Diaphragmatic
Postoperative Outcomes of Trans-abdominal Open Surgical Repair of Traumatic Diaphragmatic Hernias in Adults.
Objective: Evaluation of our management of acute or chronic traumatic diaphragmatic hernia repair with sutures or mesh. Between January 2014 and January 2019, a retrospective study on 185 patients with acute and chronic traumatic…
- Trial name
- NCT05591482
- Testing
- mesh repair
- Volunteers
- 185 people
- Sponsor
- Zagazig University
Acute Abdomen
The Role of Laparoscopy in Upper Abdominal Surgical Emergencies in Adults: A Retrospective Observational Study.
Introduction Laparoscopy can be used to diagnose and treat the etiologies of acute abdominal pain. This study aimed to assess laparoscopy's effectiveness in upper gastrointestinal (G.I.T) emergencies regarding intra-and…
- Trial name
- NCT05591495
- Testing
- laparoscopy in upper abdominal surgical emergencies in adults
- Volunteers
- 215 people
- Sponsor
- Zagazig University
Post-Dural Puncture Headache
Bilateral Sphenopalatine Ganglion Block With or Without Bilateral Greater Occipital Nerve Block for Treatment of Obstetric Post-Dural Puncture Headache
Post-dural puncture headache is a common complication, following neuraxial techniques. The obstetric population is particularly prone to PDPH. Therefore, treatment of PDPH is a key issue in obstetric anesthesia.
- Trial name
- NCT04844229
- Testing
- Bilateral transnasal sphenopalatine ganglion block., Bilateral ultrasound guided greater occipital nerve block.
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Emergencies
the Role of Laparoscopy in Lower Gastrointestinal Surgical Emergencies in Adults.
Introduction: causes of lower abdominal pain caused by various GIT emergencies, including acute appendicitis, intestinal obstruction, acute perforated diverticulitis, obstructed hernia, and iatrogenic colon perforation.
- Trial name
- NCT05584579
- Testing
- laparoscopic surgery
- Where
- Egypt
- Volunteers
- 793 people
- Sponsor
- Zagazig University
Hepatobiliary Disease
Hepatobiliary Manifestations Following Two-Stages Elective Laparoscopic Restorative Proctocolectomy for Patients With Ulcerative Colitis. A Prospective Observational Study.
Several studies using different methodological approach have revealed incomplete, old and conflicting data on the course of hepatobiliary manifestations after surgery.
- Trial name
- NCT05495178
- Testing
- laparoscopic restorative proctocolectomy
- Volunteers
- 167 people
- Sponsor
- Zagazig University
Cervical IO Plasty in Management of Placenta Previa
Cervical Internal os Plasty in Management of Placenta Previa and Focal Accreta
Aim of the work: Better management \& reducing hemorrhage and complication in patients placenta previa and focal accreta .
- Trial name
- NCT05560984
- Testing
- cervical internal os plasty
- Volunteers
- 40 people
- Sponsor
- Zagazig University
Pancreas Cancer
Outcomes of Surgical Resection of Pancreatic Cystic Neoplasms Based on the European Expert Consensus Statement: A Prospective Observational Study.
Introduction: Pancreatic cystic neoplasms (PCNs) comprise neoplasms with a wide range of benign and malignant varieties. The most common include serous cystic neoplasms (SCNs), mucinous cystic neoplasms (MCNs), intraductal…
- Trial name
- NCT04747600
- Testing
- surgical resection
- Volunteers
- 63 people
- Sponsor
- Zagazig University
Opiate Withdrawal Syndrome
Treatment of Withdrawal Symptoms and Prevention of Relapse in Patients With Tramadol Abuse
Tramadol abuse is a public health problem in Egypt. There are no approved medications for treatment of withdrawal symptoms or prevention of relapse in patients with tramadol abuse.
- Trial name
- NCT05569031
- Testing
- Venlafaxine, Lofexidine
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Zagazig University
Laparoscopic Surgery
Safe Laparoscopic Access in Patients With Previous Abdominal and Pelvic Surgery
the study discussed the safety of new technique for primary port insertion in cases of previous abdominal and pelvic surgery
- Trial name
- NCT05565508
- Testing
- new laparoscopic access technique for group a, Hasson's technique for laparoscopic access in group b
- Where
- Egypt
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Ovarian Cancer
Role of Laparoscopy in Assessing Resectability of Ovarian Cancer
Aim of Work is Prevention of unnecessary laparotomies and failed attempts to perform optimal cytoreduction in women with advanced ovarian cancer.
- Trial name
- NCT05564234
- Testing
- laparoscopy then primary cytoreductive surgery, laparoscopy then neoadjuvant chemotherapy followed by interval cytoreductive surgery
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Zagazig University