Clinical trials: sponsored by Zagazig University
Intralesional Versus Intramuscular Hepatitis B Vaccine for Multiple Common Warts
Intralesional Versus Intramuscular Hepatitis B Vaccine Immunotherapy for Warts
Assessment of the effectiveness of intralesional and intramuscular hepatitis B vaccine in treatment of multiple common warts.
- Trial name
- NCT05326152
- Testing
- hepatitis B vaccine immunotherapy of common warts (GeneVac-B 10 ml vial, Serum Institute of India Ltd., Pune, India), Intralesional saline
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Zagazig University
Non-melanoma Skin Cancers
Intralesional Versus Intramuscular Methotrexate for Non-melanoma Skin Cancers
to compare the effectiveness and safety of intralesional vs. systemic MTX in NMSC management
- Trial name
- NCT05315128
- Testing
- Methotrexate
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Laparoscopic Surgery, Acute Appendicitis With Rupture
Open to Laparoscopic Reverse Conversion of Perforated Appendicitis
A Prospective Randomized Controlled Trial of Reverse Conversion (Open to Laparoscopic) in management of Acute Perforated Appendicitis
- Conditions
- Laparoscopic Surgery, Acute Appendicitis With Rupture, Sepsis, Abdominal Abscess
- Trial name
- reverse (NCT05283733)
- Testing
- reverse conversion technique
- Where
- Egypt
- Volunteers
- 426 people
- Sponsor
- Zagazig University
Spine Surgery
Incidence , Risk Factors and Outcomes of Haemodynamic Instability and Cardiac Arrest During Spine Surgery
Risk factors for cardiac arrest during spine surgery have been well defined, including lumbar fusion, age over 65 years, obesity, cardiovascular disease, ethnicity and ASA status.
- Trial name
- NCT05131854
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Zagazig University
COVID-19
Criteria and Potential Predictors of Severity in Patients With COVID-19
This is an observational cross sectional study included 202 patients diagnosed to have COVID-19. The study was conducted at Zagazig University Isolation Hospitals from the period of March 2020 to June 2021.
- Trial name
- NCT05218265
- Testing
- routine laboratory tests
- Where
- Egypt
- Volunteers
- 202 people
- Sponsor
- Zagazig University
Peripheral Perfusion, Postoperative Pain
Effects Magnesium Sulfate and Labetalol Infusion on Peripheral Perfusion and Pain in Nasal Surgeries
One of main risk of controlled hypotension during nasal surgeries is impaired perfusion. Peripheral perfusion of non-vital organs usually impaired earlier than vital organs.
- Trial name
- NCT04688203
- Testing
- Magnesium Sulfate Injection, Labetalol Injectable Solution
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Triple Intralesional Immunotherapy Combination in Multiple Recalcitrant Warts
Triple Antigen vs Monoantigen Immunotherapy for Warts
Warts can be resistant to treatment or return despite the use of many therapeutic modalities. Combining immunotherapy might contribute to better response rates, particularly in recalcitrant warts, which is a real therapeutic…
- Trial name
- NCT05254561
- Testing
- Intralesional antigen immunotherapy
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Zagazig University
Colorectal Disorders
Enhanced Recovery Program After Laparoscopic Colorectal Surgery During The Era Of COVID-19
The investigators included all patients who were subjected to laparoscopic colorectal surgery at investigators' center between ( December 2019 to December 2021) for benign \& malignant conditions.
- Trial name
- NCT05240053
- Testing
- enhanced recovery programe
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Zagazig University
Treatment
Novel Technique Lumber Spine Fusion: Unilateral Pedicular Screws Fixation Combined With Contralateral Interbody Cage
● Null hypothesis (H0): Unilateral pedicle screw with contralateral interbody cage has better outcomes than unilateral pedicle screw fixation with ipsilateral cage.
- Trial name
- NCT05238662
- Testing
- pedicle screw fixation on one side and intervertebral cage on the other sided, pedicle screw fixation and interbody cage on the same side
- Volunteers
- 40 people
- Sponsor
- Zagazig University
Vaccine Adverse Reaction, Seroconversion
Safety and Immunogenicity of Oxford AstraZeneca Vaccine Against COVID-19 Infection
After SARS-COV-2 inactivated vaccine authorization for use in different countries including Egypt, investigating its immunogenicity, safety, and efficacy in preventing COVID-19 infection is highly needed.
- Trial name
- NCT04756271
- Testing
- SARS-Cov-2 neutralizing antibody titer
- Where
- Egypt
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Acute Post-operative Pain, Cholecystectomy, Laparoscopic
Optimizing Pain Management Following Laparoscopic Cholecystectomy RCT
evaluating the two final steps we added to optimize post laparoscopic cholecystectomy pain management.
- Conditions
- Acute Post-operative Pain, Cholecystectomy, Laparoscopic, Pain Assessment Pain Intensity, Pain Intensity
- Trial name
- Pain (NCT05214157)
- Testing
- active gas aspiration
- Where
- Egypt
- Volunteers
- 804 people
- Sponsor
- Zagazig University
Analgesia
Ultrasound Guided : Retrolaminar Block Versus Thoracic Epidural Analgesia Following Laparoscopic Cholecystectomy
The aim of this study is to evaluate analgesic effect of ultrasound-guided retrolaminar block vs ultrasound-guided thoracic epidural analgesia in pain control following laparoscopic cholecystectomy.
- Trial name
- NCT04835415
- Testing
- Bilateral retrolaminar block, Thoracic epidural analgesia
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Ectopic Pregnancy
Evaluation of Different Doses of Letrozole in Ectopic Pregnancy
The utilization of letrozole at a daily dose of 10 mg for medical treatment of ectopic pregnancy considerably has a high success rate without imposing any serious side effects compared to daily 5mg letrozole.
- Trial name
- letrezole (NCT05198141)
- Testing
- Letrozole tablets, laparoscopic salpingectomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Bariatric Surgery Candidate
Sleeve Gastrectomy and Cholecystectomy Are Safe in Obese Patients With Asymptomatic Cholelithiasis
Introduction: Obesity is an increasingly serious public health problem on a global level. Gallstones may become symptomatic after sleeve gastrectomy surgery.
- Trial name
- NCT04878640
- Testing
- patients with morbid obesity and gall bladder stone underwent concomitant laparoscopic cholecystectomy in the same setting during laparoscopic sleeve gastrectomy, patients with morbid obesity and gall bladder stone underwent laparoscopic sleeve gastrectomy without concomitant laparoscopic cholecystectomy
- Volunteers
- 222 people
- Sponsor
- Zagazig University
Dyspepsia, Heartburn
Bile Reflux Gastropathy: Prevalence and Risk Factors After Therapeutic Biliary Interventions
Bile reflux gastropathy is caused by the backward flow of duodenal fluid into the stomach. A retrospective cohort study was performed to declare if the therapeutic biliary interventions cause bile reflux gastropathy, and to…
- Conditions
- Dyspepsia, Heartburn, Bile Reflux
- Trial name
- NCT05131802
- Testing
- upper GIT endescopy
- Where
- Egypt
- Volunteers
- 288 people
- Sponsor
- Zagazig University
Acute Myeloid Leukemia, Vitamin D Deficiency
Vitamin D Effect on A Disintegrin-like And Metalloprotease Thrombospondin1 Motif 13& Interleukin 6 in Leukemia
A Disintegrin-like And Metalloprotease with Thrombospondin type 1 motif 13 (ADAMTS13) deficiency was incriminated in poor prognosis, high probability of serious complications and mortality in acute myeloid leukemia (AML)…
- Conditions
- Acute Myeloid Leukemia, Vitamin D Deficiency, ADAMTS13, Interleukin 6
- Trial name
- NCT05149339
- Testing
- Cholecalciferol 2800 I.U. ml oral drops
- Where
- Egypt
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Analgesia
Opioid Sparing Analgesia: Dexmedetomidine Versus Lidocaine for Intracranial Surgeries in Children
Perioperative pain control is necessary in children as inadequate treatment may lead to progression of perception of pain and development of chronic pain in the future.
- Trial name
- NCT04535089
- Testing
- Dexmedetomidine injection, Lidocaine Iv
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Zagazig University
COVID-19 Acute Respiratory Distress Syndrome
Is Fetal Hemoglobin a Key for Improvement of Hypoxia and Saving Last Breath in COVID-19 Patient?. A Pilot Study.
In December 2019, a sudden public health incident (the corona virus disease [COVID-19] epidemic) occurred in Wuhan, China. Clinical features of those with pneumonia include fever and cough, and in many cases a sudden and…
- Trial name
- NCT05092724
- Testing
- fetal blood transfusion
- Volunteers
- 20 people
- Sponsor
- Zagazig University
Electrolyte Imbalance
Electrolyte State in Patients With COVID-19
Initial case reports and cohort studies have described many clinical characteristics of patients with coronavirus disease 2019 (COVID-19), an emerging infectious disorder caused by the severe acute respiratory syndrome…
- Trial name
- NCT04539834
- Testing
- electrolytes
- Where
- Egypt
- Volunteers
- 983 people
- Sponsor
- Zagazig University
Colon Cancer
Combined Medial and Caudal Approach for Right Hemicolectomy
Right sided hemicolectomy is the standard type of operation for cancers in the caecum, the ascending colon, proximal transverse colon.The aim of this study was to assess the safety and feasibility of combined medial and caudal…
- Trial name
- NCT05128708
- Testing
- combined medial and caudal approach right hemicolectomy open and laparoscopic
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Zagazig University