Clinical trials: sponsored by Zagazig University
Spinal Anaesthesia, Spinal Anesthesia Evaluation
Lipid Emulsion for Reversal of Spinal Anesthesia in Ambulatory Surgery
Ambulatory surgery places high demands on anesthetic technique. rapid onset and offset of anesthesia, rapid recovery of protective reflexes, mobility and micturition, are required.
- Conditions
- Spinal Anaesthesia, Spinal Anesthesia Evaluation, Ambulatory Surgery
- Trial name
- NCT06988982
- Testing
- Intravenous Lipid Emulsion 20%
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Zagazig University
Analgesia, Disk Herniated Lumbar
Analgesia Following Lumbar Discectomy
Lumbar discectomy surgeries are often the last option for patients with disc herniation who do not improve with conservative treatments.
- Conditions
- Analgesia, Disk Herniated Lumbar, Local Infiltration
- Trial name
- NCT06869889
- Testing
- Retrolaminar plane block, Local wound infiltration
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Zagazig University
Upper Gastrointestinal Endoscopy, Topical Anesthesia
Oropharyngeoesophageal Topical Anesthesia Versus Intravenous Propofol -Ketamine Sedation for Upper Gastrointestinal Endoscopy
Esophagogastroduodenoscopy (EGD) is an essential and widely used diagnostic and therapeutic procedure in gastroenterology. EGD can be performed in association with topical anesthesia of the pharynx, intravenous anesthesia, or…
- Conditions
- Upper Gastrointestinal Endoscopy, Topical Anesthesia, Intravenous Sedation
- Trial name
- NCT07563062
- Testing
- Propofol and Ketamine Mixture (Ketofol), Modified Oropharyngeo-esophygeal Topical Anesthesia by OPETA Prototype tool
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Regional Anesthesia for Shoulder Surgery
Shoulder Anterior Capsule Block Combined With Supra Scapular Nerve Versus Interscalene Block as Sole Anesthesia in Shoulder Arthroscopy
Evaluation of shoulder anterior capsule nerve block combined with suprascapular nerve block as an adequate sole anesthetic technique in shoulder arthroscopic surgeries without significant affection of motor power and pulmonary…
- Trial name
- NCT07649460
- Testing
- Shoulder anterior capsule nerve block, Interscalene Nerve Block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Zagazig University
Cervical Cancer
Laparoscopic Versus Open Radical Hysterectomy in Early-Stage Cervical Cancer
The study aims to compare laparoscopic-assisted radical hysterectomy with open radical hysterectomy in women with early-stage cervical cancer.
- Trial name
- LAP-OPEN (NCT07626996)
- Testing
- Laparoscopic Radical Hysterectomy, Open Radical Hysterectomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Postoperative Pain After Total Knee Arthroplasty
Genicular Nerve Versus Adductor Canal Block for Postoperative Analgesia
Severe postoperative pain following total knee arthroplasty (TKA ) has been shown to negatively affect early mobilization, physical rehabilitation, time to discharge, and overall post-operative recovery.Therefore, reducing…
- Trial name
- NCT07588958
- Testing
- Spinal Anesthesia with Bupivacaine and Fentanyl, Genicular nerve block with bupivacaine, Adductor Canal Block (ACB) Only
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Zagazig University
Endometriosis
Diagnostic Accuracy of Plasma MicroRNA 125b-5p and 141-3p for Early Endometriosis
Endometriosis (EM) is a chronic gynecological disorder characterized by distressing pain and a high risk of infertility. While exploratory laparoscopy is currently the standard for diagnosis and staging, it is an invasive…
- Trial name
- NCT07586488
- Testing
- Staging Laparoscopy, Laboratory Biomarker Assessment (Mirs and CA-125), Transvaginal Ultrasound (TVS) Staging
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Intraoperative Bleeding, Functional Endoscopic Sinus Surgeries
Dexmedetomidine Versus Nitroglycerin on Surgical Field Quality and Drug Cost in Functional Endoscopic Sinus Surgeries
Sinus surgery is one of the most prevalent ear, nose, and throat (ENT) surgeries, which is mainly carried out nowadays through functional endoscopic sinus surgery (FESS) and leads to significant improvement in the clinical…
- Conditions
- Intraoperative Bleeding, Functional Endoscopic Sinus Surgeries, Hypotension
- Trial name
- NCT07585201
- Testing
- controlled hypotension using dexmedetomidine, controlled hypotension hypotension using nitroglycerin
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Zagazig University
Chronic Obstructive Pulmonary Disease (COPD), With Poitive H Pylori
Impact of Eradication Therapy on Helicobacter Pylori Infection With Chronic Obstructive Pulmonary Disease:
Helicobacter pylori (HP) is a well-established pathogen responsible for chronic gastritis and peptic ulcer disease. Its presence has been implicated in the development of gastric malignancies such as adenocarcinoma and…
- Trial name
- NCT07574879
- Testing
- Eradication of Helcobacter Pylori
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Zagazig University
Striae Distensae
PRP vs PRF in Management of Striae Distensae
A split-side comparative clinical study evaluating the efficacy and safety of injectable platelet-rich fibrin (PRF) versus platelet-rich plasma (PRP), alone or combined with microneedling, in the treatment of striae distensae.
- Trial name
- NCT07561671
- Testing
- PRF group, PRP injection, PRF and microneedling
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Zagazig University
Pain, Chronic
Management Modalities of Chronic Pelvic Pain
Chronic pelvic pain remains a challenging disorder to treat because of the complexities of pain sensation and unclear etiology. Standard medical and surgical treatments seldom prove effective at improving quality of life and pain…
- Trial name
- NCT06719635
- Testing
- Laparoscopic Presacral Neurectomy, Fluoroscopically guided Superior Hypogastric Plexus Neurolysis
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Zagazig University
Atrophic Scar
Exososmes in Atrophic Scars Management
Lay Summary (Simple Explanation) Atrophic scars are depressed scars that form when the skin does not heal properly, commonly seen after acne or injuries.
- Trial name
- NCT07569666
- Testing
- Intralesional exosomes, Intralesional Saline
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Zagazig University
Stress Response of Endotracheal Intubation and Surgical Field Clarity in FESS
Melatonin vs Metoprolol or Dexmedetomidine to Improve Surgical Field in FESS
This randomized controlled study at Zagazig University Hospitals will include 112 patients undergoing elective functional endoscopic sinus surgery, allocated into four groups (Melatonin, Metoprolol, Dexmedetomidine, Control).
- Trial name
- NCT07568873
- Testing
- Melatonin, Metoprolol (MET), Dexmedetomidine
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Zagazig University
Analgesia, Recovery, Psychological
Enhanced Recovery After Uvulopalatoplasty
Obstructive sleep apnea is a prevalent condition often treated surgically with palatoplasty, which improves airway patency and reduces apneic events.
- Trial name
- NCT07246694
- Testing
- Glossopharyngeal nerve block, Standard multimodal analgesia
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Zagazig University
Postherpetic Neuralgia ( PHN )
Intradermal Exosomes, Platelet-Rich Plasma, and Steroids for Post-Herpetic Neuralgia
This randomized controlled clinical trial will evaluate and compare the efficacy and safety of intradermal injection of exosomes, platelet-rich plasma, and corticosteroid in patients with post-herpetic neuralgia.
- Trial name
- NCT07565844
- Testing
- Exosomes, PRP, Corticosteroids
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Zagazig University
Supraglottic Airway Devices, Laryseal Clear Laryngeal Mask
Clinical Performance of Laryseal Clear Versus Ambu Aura 40 Laryngeal Mask Airway for Preschool Children
Preschool children have specific anatomical and physiological characteristics which necessitates careful selection of an appropriate airway management device.
- Trial name
- NCT07553247
- Testing
- LarySeal clear Group, Ambu Aura40 Group
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Zagazig University
Fracture Rib
Rhomboid Intercostal and Sub-Serratus Block for Improving Pulmonary Function and Pain in Patients With Fracture Ribs
Rib fractures are seen in more than 50% of patient spresenting with blunt chest trauma and are associated with significant morbidity, long-term disability and mortality .
- Trial name
- NCT05898958
- Testing
- thoracic paravertebral block, rhomboid intercostal and subserratus block
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Zagazig University
Onychomycosis
Isotretinoin Versus Excimer Light an Adjuvant in Treating Onychomycosis
3 groups of patients with onychomycosis will be recruited. Group A will receive itraconazole alone. Group B will receive itraconazole + low dose isotretinoin and group C will be treated with itraconazole + excimer light sessions.
- Trial name
- NCT06485505
- Testing
- ISOtretinoin 10 MG, excimer light, Itraconazole 200 mg
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Zagazig University
Laparoscopic Cholecystectomy Surgery
Cystic Artery Dissection With Dorsal Infundibular Approach Versus Critical View of Safety
We evaluated the efficacy of combining cystic artery dissection with a dorsal infundibular approach in comparison to the critical view of safety.
- Trial name
- NCT07507292
- Testing
- critical view of saftey, cystic artery dissection with dorsal infundibular dissection
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Zagazig University
Hiatal Hernia, Sleeve Gastrectomy
Laparoscopic Hiatal Hernia Repair With Mesh Cruroplasty
The study you're referring to explores a surgical strategy for patients undergoing Laparoscopic Sleeve Gastrectomy (LSG) who also have a Hiatal Hernia (HH).
- Trial name
- NCT07491003
- Testing
- Hiatal Hernia (HH) repair using mesh cruroplasty during a Laparoscopic Sleeve Gastrectomy (LSG)
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Zagazig University