Clinical trials: sponsored by Zagazig University
Laparoscopic Cholecystectomy, Quadratus Lumborum Block
Erector Spinae Plane Block Versus Subcostal Anterior Quadratus Lumborum Block in Laparoscopic Cholecystectomy
Adequate analgesic regimen is one of the most important key elements of Enhanced recovery after surgery (ERAS) protocols. The cornerstone of analgesia is multimodal analgesia combining local anesthetic (LA) techniques and trying…
- Conditions
- Laparoscopic Cholecystectomy, Quadratus Lumborum Block, Erector Spinae Plane Block
- Trial name
- NCT05158270
- Testing
- Ultrasound Guided Erector spinae plane block, Ultrasound Guided Subcostal Anterior Quadratus Lumborum Block, Intravenous Multimodal Analgesia
- Where
- Egypt
- Volunteers
- 81 people
- Sponsor
- Zagazig University
Adenomyosis
Adenomyosis and Pregnancy: Levonorgestrel vs. GnRH for Blastocyst Transfer
Adenomyosis is a condition where endometrial tissue grows into the uterine muscle, causing symptoms like pelvic pain, heavy bleeding, and infertility.
- Trial name
- NCT06581679
- Testing
- Triptorelin, levonorgestrel-releasing intrauterine system, frozen embryo transfer
- Where
- Egypt
- Volunteers
- 184 people
- Sponsor
- Zagazig University
Awake Fiberoptic Intubation
Atomization Vs. Nebulization for Airway Topicalization During Awake Nasotracheal Fiberoptic Intubation
Intubation of difficult airway is a challenge for anesthetist. There many causes of difficult airway, and previous studies concluded that awake fiber-optic intubation (AFOI) is the gold standard for the management of these…
- Trial name
- NCT05320731
- Testing
- Nebulization with lidocaine, Atomization with lidocaine
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Zagazig University
Sepsis-associated Encephalopathy
Optic Nerve Sheath Diameter / Eyeball Transverse Diameter Ratio and Prognosis of Sepsis Associated Encephalopathy
Sepsis is associated with a mortality rate of 20-25%, with significant increase in case of associated comorbidities or shock. SAE is one of the most common forms of encephalopathy encountered in critically ill patients, with…
- Trial name
- NCT05918705
- Testing
- Ultrasound optic nerve sheath diameter / eyeball transverse diameter ratio
- Where
- Egypt
- Volunteers
- 89 people
- Sponsor
- Zagazig University
Upper Gastrointestinal Endoscopy, Topical Anesthesia
Oropharyngeoesophageal Topical Anesthesia Versus Propofol - Ketamine Sedation for Upper Gastrointestinal Endoscopy
Esophagogastroduodenoscopy (EGD) is an essential and widely used diagnostic and therapeutic procedure in gastroenterology. EGD can be performed in association with topical anesthesia of the pharynx, intravenous anesthesia, or…
- Conditions
- Upper Gastrointestinal Endoscopy, Topical Anesthesia, Intravenous Sedation
- Trial name
- NCT06566326
- Testing
- Propofol and ketamine, Modified Oropharyngeo-esophygeal Topical Anesthesia by OPETA Prototype tool
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Malnutrition
Incidence Rate and Risk Factors of Malnutrition in ICU
To assess the incidence of malnutrition in surgical Intensive Care Unit by NUTRIC score. To determine the different risk factors of malnutrition
- Trial name
- NCT06047054
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Zagazig University
Different Methods to Minimize Blood Loss During Laparoscopic Myomectomy
Different Methods to Minimize Blood Loss During Laparoscopic Myomectomy; A Randomized Controlled Clinical Trial
Laparoscopic myomectomy with temporary bilateral uterine artery occlusion or intramyometrial injection of diluted epinephrine will be important to reduce intraoperative bleeding, time of operation and hospitalization period after…
- Trial name
- NCT06566352
- Testing
- Laparoscopic myomectomy with intramyometrial injection of diluted epinephrine, traditional laparoscopic myomectomy, laparoscopic myomectomy with temporary bilateral uterine artery occlusion
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Preemptive Paracetamol Plus Tramadol and Preemptive Fentanyl
Paracetamol Plus Tramadol Versus Fentanyl As Preemptive Analgesia For Enhanced Recovery After Day Case Surgeries
Implementation of enhanced recovery in day case surgeries using either preemptive intravenous paracetamol plus tramadol or preemptive intravenous fentanyl.
- Trial name
- NCT06561672
- Testing
- tramadol plus paracetamol, Fentanyl, propofol and muscle relaxant (cisatracurium)
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Zagazig University
Subanesthetic Ketamine Dexmedetomidin
Intraoperative Subanesthetic Ketamine Versus Dexmedetomidine Infusion for Prevention of Post-traumatic Stress Disorder After Traumatic Brain Surgeries
Prevention of Post-traumatic Stress Disorder after traumatic Brain surgeries by using either subanesthetic ketamine or dexmedetomidine infusion.
- Trial name
- NCT06498700
- Testing
- ketamine, dexmedetomidine
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Zagazig University
Postoperative Pain
Intrathecal Pethidine Plus Dexamethasone for Distal Lower Orthopedic Surgeries
Bupivacaine is commonly used as a sole agent for spinal anesthesia unlike pethidine. Pethidine (meperidine) is a unique opioid. In addition to its analgesic activity, it also has significant local anesthetic activity.
- Trial name
- NCT05303311
- Testing
- Bupivacaine Hydrochloride, Pethidine plus Dexamethasone
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Acne Scars - Atrophic
Stromal Vascular Fraction Enriched PRP in Treatment of Post-acne Scars
in a split face fashion, 30 patients will be randomized into 3 groups: Group A: rt side treated with SVF enriched PRP, lt side treated with prp Group B: rt side treated with SVF enriched PRP, lt side treated with SVF Group C: rt…
- Trial name
- NCT06524011
- Testing
- Stromal vascular fraction (SVF) enriched platelet rich plasma (PRP) versus each alone
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Non-Alcoholic Fatty Liver Disease
Fetuin-A, a Promising Serum Biomarker for Diagnosis of Non-Alcoholic Fatty Liver Disease
The work investigate the role of fetuin-A in the diagnosis and assessment of the severity of non-alcoholic fatty liver disease (NAFLD).
- Trial name
- NAFLD (NCT06097039)
- Testing
- abdominal U/S, Fibroscan with Controlled Attenuated Parameter (CAP scan):
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Malignant Biliary Obstruction
Multihole Fully Covered Metallic Stents in the Management of Malignant Biliary Obstruction
multiholes fully covered metallic stents in the management of malignant biliary obstruction
- Trial name
- NCT05786326
- Testing
- group 1, group 2, group 3
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Zagazig University
Urinary Titin
The Validity of Urinary Titin and Skeletal Muscle Index as Predictor of Muscle Weakness in Critically Ill Patients. A Prospective Cohort Study
Although skeletal muscle atrophy is common in critically ill patients, biomarkers associated with muscle atrophy have not been identified reliably.
- Trial name
- NCT06487728
- Testing
- Urinary titin
- Where
- Egypt
- Volunteers
- 161 people
- Sponsor
- Zagazig University
Airway Complication of Anesthesia
Assessment of Pediatric Challenging Airway
The goal of these Observational study is to learn about pediatric airway the main question to answer is: 1-Is using point-of-care ultrasound provide an easy, early, and accurate preoperative assessment of the challenging…
- Trial name
- NCT06443424
- Testing
- ultrasound device
- Where
- Egypt
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Zagazig University
adrenalDisease
Side-specific Factors for Intraoperative Hemodynamic Instability in Pheochromocytoma
The performance of adrenalectomy for pheochromocytoma (PHEO) presents significant challenges due to the presence of elevated intraoperative hemodynamic instability (HI) and conversion risk.
- Trial name
- NCT06064370
- Testing
- laparoscopic adrenalectomy
- Volunteers
- 171 people
- Sponsor
- Zagazig University
Sepsis
Optic Nerve Sheath Diameter for Prediction of Sepsis Associated Encephalopathy
Sepsis-associated brain dysfunction (SABD)with increased intracranial pressure is a complex pathology that can lead to unfavourable outcome.
- Trial name
- NCT05849831
- Testing
- Ultrasound measurement of Optic nerve sheath diameter
- Where
- 2 sites in Egypt
- Volunteers
- 89 people
- Sponsor
- Zagazig University
Pregnancy Tubal
Sequential Letrozole and Methotrexate Therapy Role in Treatment of Tubal Ectopic Pregnancy
Ectopic pregnancy (EP) is a common condition involving the implantation of fertilized ovum outside the uterine cavity, accounting for 1-2% of all pregnancies.
- Trial name
- NCT06426979
- Testing
- Methotrexate, Letrozole
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Zagazig University
Psoriasis
Low-Dose Enoxaparin in Psoriasis
Rationale: Psoriasis is a chronic immune-mediated inflammatory skin disorder where T cells play a fundamental role in its pathogenesis.
- Trial name
- NCT06416566
- Testing
- Subcutaneous Enoxaparin
- Volunteers
- 30 people
- Sponsor
- Zagazig University
Inflammatory Bowel Diseases, Anal Fissure
Laser Versus Surgery in Anal Diseases in Inflammatory Bowel Patients
This is a randomized comparative clinical trial carried out to compare between laser ablation and surgery in treating anal diseases in inflammatory bowel diseases patients and find out if one is superior to the other.
- Conditions
- Inflammatory Bowel Diseases, Anal Fissure, Hemorrhoids
- Trial name
- NCT06216223
- Testing
- treatment of anal diseases in inflammatory bowel patients, Laser, traditional surgery
- Where
- Egypt
- Volunteers
- 108 people
- Sponsor
- Zagazig University