Clinical trials: sponsored by Georgetown University
Posttraumatic Stress Disorder
Comparative Effectiveness of Two Treatments for Veterans With PTSD
Interpersonal problems such as relationship conflict and social isolation are common among Veterans with PTSD and serve as barriers to successful posttraumatic adjustment.
- Trial name
- NCT02586064
- Testing
- Interpersonal Therapy for PTSD, Prolonged Exposure
- Where
- 2 sites in United States
- Volunteers
- 115 people
- Sponsor
- VA Office of Research and Development
Social Behavior
Metta Meditation Training on Prosocial Behavior
The purpose of the study is to look at the impact of a metta meditation training on prosocial behavior and socio-affective brain responses.
- Trial name
- NCT03894930
- Testing
- Metta meditation
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Meditation
Online Trial of Meditation and Behavior
This study investigates how different types of meditation may affect behaviors and emotions. The study is conducted entirely online and involves listening to 4-weeks of a guided meditation training.
- Trial name
- NCT04632875
- Testing
- Loving-Kindness Meditation, Relaxation Meditation
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Pancreas Cancer, Hepatobiliary Cancer
NCI SBIR Contract for Patient Navigation Tool Prototype Development
GMG ArcData will create a mobile-based application to improve communications and data exchange among patients and navigators involved in new pancreas surgery oncology episodes of care.
- Conditions
- Pancreas Cancer, Hepatobiliary Cancer, Patient Engagement
- Trial name
- NCT04892927
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- GMG Arcdata LLC
Hypertension, COVID
ACEI or ARB and COVID-19 Severity and Mortality in US Veterans
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for COVID-19, enters type II pneumocytes using angiotensin-converting enzyme 2 (ACE2).
- Trial name
- NCT04467931
- Testing
- ACEI/ARB, Non-ACEI/ARB, ACEI
- Where
- United States
- Volunteers
- 22,213 people
- Sponsor
- University of Utah
Small Cell Lung Cancer, Small Cell Lung Cancer Extensive Stage
Nivolumab and 177Lu-DOTA0-Tyr3-Octreotate for Patients With Extensive-Stage Small Cell Lung Cancer
This research study is being done to assess the safety and tolerability of study drugs, 177Lu-DOTA0-Tyr3-Octreotate (Lutathera) and nivolumab in subjects with small cell lung cancer or advanced or inoperable neuroendocrine tumor…
- Trial name
- NCT03325816
- Testing
- Nivolumab, 177Lu-DOTA0-Tyr3-Octreotate
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- Georgetown University
Thyroid Carcinoma, Hypothyroidism
The Effect of Coffee on the Absorption of Thyroid Hormone in Patients With Thyroid Carcinoma
The purpose of this study is to evaluate whether taking thyroid hormone medication with beverages other than water, decreases absorption of the medication by the intestine.
- Trial name
- NCT01707056
- Testing
- Black Coffee, Coffee with Milk, Black Tea
- Where
- 3 sites in United States
- Sponsor
- Medstar Health Research Institute
Breast Cancer
Web-Based Communication Education for Breast Cancer Survivorship Care
This two-phase research plan will develop and test a culturally relevant, web-based patient education program, hereafter known as E-Talkcare.
- Trial name
- NCT03413332
- Testing
- E-Talkcare, Usual Care
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Georgetown University
HIV, Hepatitis C
Sofosbuvir Based DAA Therapy in HIV/HCV Coinfected Pre or Post Liver Transplant
Retrospective/Prospective, open-label study using sofosbuvir based DAA therapy to treat HIV/HCV coinfected pre or post liver transplant participants
- Conditions
- HIV, Hepatitis C, Cirrhosis
- Trial name
- STOP-CO (NCT02533934)
- Testing
- Harvoni
- Where
- 8 sites in United States
- Volunteers
- 68 people
- Sponsor
- University of California, San Francisco
Breast Cancer
Acupressure for Cancer-Related Fatigue
This study develops and pilot tests the efficacy of a home-based, self-administered acupressure intervention in improving cancer-related fatigue (proximal outcome), and physical functioning and other quality of life outcomes…
- Trial name
- NCT03091647
- Testing
- acupressure intervention, usual care
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Georgetown University
Gulf War Syndrome
Glutamate Neuro-Excitotoxicity in GWI
The objective of the proposed research is to examine whether dietary exposure to food additives containing glutamate may be contributing to symptoms in Gulf War Illness (GWI).
- Trial name
- GWI (NCT03342482)
- Testing
- Low-glutamate diet
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- American University
Breast Cancer, Mastectomy; Lymphedema
Same-Day Discharge After Nipple-sparing Mastectomy or Skin-sparing Mastectomy With Breast Reconstruction
This novel study will assess the feasibility and outcomes of same-day discharge following mastectomy with implant-based pre-pectoral reconstruction.
- Conditions
- Breast Cancer, Mastectomy; Lymphedema, Same Day Surgery, Nipple-sparing Mastectomy
- Trial name
- NCT04596683
- Testing
- Same-day NSM or SSM
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Georgetown University
Post-operative Pain, Post-operative Nausea and Vomiting
Multimodal Perioperative Pain Management: ComfortSafe Program
Proposed is a demonstration project to characterize the immediate, short-term and long-term pain and other post-operative outcomes of 60, self-selected breast (n=20), caesarian-section (n=20) and abdominal (n=20) surgical…
- Conditions
- Post-operative Pain, Post-operative Nausea and Vomiting, Respiratory Depression, Confusion Postoperative
- Trial name
- NCT04046068
- Testing
- ComfortSafe Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Georgetown University
Wounds and Injuries
Bacterial Load for Integra™ in Operative Wounds
Proportion of postoperative complications (infections, dehiscence, graft slough) after initial application of Integra™
- Trial name
- NCT04543240
- Testing
- Integra™ dermal regeneration template
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Georgetown University
Stroke Prevention, Blood Pressure Reduction
STEPs to Blood Pressure Reduction.
The Stroke Transitions Education and Prevention (STEP) Clinic is a new type of clinic designed for stroke patients and was established to provide a comprehensive approach to stroke risk factor reduction.
- Trial name
- STEPS (NCT02591394)
- Testing
- STEP Clinic, Usual Care
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- The University of Texas Health Science Center, Houston
Diabetes Mellitus
Evaluating the Effects of Kombucha as a Hyperglycemic Therapeutic Agent Within Diabetic Human Subjects
This study's primary objective is to determine the ability of Kombucha to impact blood sugar levels in patients with diabetes mellitus type II.
- Trial name
- NCT04107207
- Testing
- Ginger Kombucha, Ginger Water
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Mastectomy, Breast Cancer
Post-Mastectomy Analgesia Using Exparel (Liposomal) Versus Standard Bupivacaine or Placebo
This is a randomized, single-blinded placebo-controlled trial. Patients will be randomized to one of three arms: (1) injection of liposomal bupivacaine at the end of the operation, (2) injection of standard bupivacaine at the end…
- Trial name
- NCT03504865
- Testing
- Liposomal bupivacaine, Standard bupivacaine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Georgetown University
HIV
Palliative Care in People Living With HIV/AIDS: Integrating Into Standard of Care
Our goal is to advance palliative care with persons living with AIDS (PLWA) or life-limiting co-morbidities to decrease suffering and increase quality of life (QOL).
- Trial name
- FACE (NCT01775436)
- Testing
- FAmily-CEntered Advance Care Planning, Healthy Living Control
- Where
- 5 sites in United States
- Volunteers
- 444 people
- Sponsor
- Children's National Research Institute
Stroke
Stroke Transitions of Care to Reduce Hospital Length of Stay
The purpose of this prospective pilot study is to access the feasibility of Transitions of Care Coordinator (TOCC) program, to determine if the use of a TOCC will decrease hospital length of stay (LOS), and determine if…
- Trial name
- TOCC (NCT04434638)
- Testing
- Transitions of Care Coordinator, Usual Care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Georgetown University
Transplant; Intestine, Transplant; Complication, Rejection
The Endoscopic Assesment of Intestinal Grafts
The study validates prospectively a new endoscopic scoring system (Gothenburg Intestinal Transplant Endoscopy Score, GITES) designed to summarize and stratify the abnormal ileal endoscopic findings after intestinal…
- Conditions
- Transplant; Intestine, Transplant; Complication, Rejection, Transplant; Failure, Bowel, Enteritis
- Trial name
- INTEGRATE (NCT03444675)
- Where
- 4 sites in United States, Argentina and 2 more
- Volunteers
- 80 people
- Sponsor
- Sahlgrenska University Hospital