Clinical trials: sponsored by Georgetown University
Lower Urinary Tract Symptoms
Impact of Probiotics on Urinary Symptoms in Spinal Cord Injury SCI and SB
As a collaborative effort between MedStar National Rehabilitation Hospital (NRH)/MedStar Health Research Institute (MHRI), Children's National Medical Center (CNMC) Department of Urology, Children's Research Institute (CRI)…
- Trial name
- NCT02748317
- Testing
- Lactobacillus rhamnosus GG
- Where
- 2 sites in United States
- Volunteers
- 96 people
- Sponsor
- Medstar Health Research Institute
Lower Urinary Tract Symptoms
Impact of Probiotics on Urinary Symptoms in Spinal Cord Injury SCI and SB
As a collaborative effort between MedStar National Rehabilitation Hospital (NRH), Children's National Medical Center (CNMC) Department of Urology, Children's Research Institute (CRI) Center for Genetic Medicine Research…
- Trial name
- NCT02748356
- Testing
- Lactobacillus
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- Medstar Health Research Institute
Autism Spectrum Disorder
Executive Function Intervention for High School Students With ASD
The purpose of this project is to test the effectiveness of a novel school-based intervention targeting executive function skills, including flexibility and planning, in college-track, transition-age youth with ASD.
- Trial name
- NCT03199937
- Testing
- Flexible Futures, Current standard of care
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Children's National Research Institute
Ischemic Stroke, Hypertension
Home Blood Pressure Study for Recent Stroke Survivors With High Blood Pressure *On Hold Due to Global Pandemic*
The purpose of this pilot study is to assess the feasibility of implementing a home blood pressure self-management program in a population of recent stroke survivors in the Washington, D.C. area.
- Trial name
- HBPS (NCT04226157)
- Testing
- Home Blood Pressure Monitoring Device (Qardio Arm), Primary Care Provider Blood Pressure Management
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- MedStar Georgetown University Hospital
Stroke, Brain Infarction
Critical Periods After Stroke Study (CPASS)
To perform an exploratory single center randomized study that will form the basis for a larger scale, more definitive randomized clinical trial to determine the optimal time after stroke for intensive motor training.
- Conditions
- Stroke, Brain Infarction, Brain Ischemia, Cerebral Infarction
- Trial name
- CPASS (NCT02235974)
- Testing
- Early Intensive upper extremity motor training, Sub-acute intensive upper extremity motor training, Chronic intensive upper extremity motor training
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- MedStar National Rehabilitation Network
Renal Transplant Recipients
Envarsus XR in African American Renal Transplant Recipients
The purpose of this study is to collect data prospectively on African American patients who are taking the immunosuppressant Envarsus post kidney transplant.
- Trial name
- EXR (NCT02956005)
- Testing
- ENVARSUS®
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Georgetown University
Chronic Venous Hypertension With Ulcer
ActiV.A.C.+ Compression Therapy Versus Compression Therapy Alone for the Treatment of Chronic Venous Ulcerations
This is a prospective, randomized, comparative interventional human subject trial. Patients with a chronic venous ulceration of the lower extremity will be enrolled into this study.
- Trial name
- NCT01528293
- Testing
- ActiVAC System, Compression therapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Georgetown University
Colorectal Cancer
Panitumumab and Bortezomib for Patients With Advanced Colorectal Cancer
Panitumumab plus bortezomib for colon cancer
- Trial name
- NCT01504477
- Testing
- Panitumumab and bortezomib
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Georgetown University
Peripheral Vascular Disease
Pilot Study to Determine Percent Tissue Perfusion and Cellular Viability Using SPY Imaging
Little is known about chronic wound microenvironments, especially in peripheral vascular disease (PVD) and diabetic patients. At the demarcation line, the percentage of viable cells and tissue is unclear.
- Trial name
- NCT01522495
- Testing
- SPY Imaging, ICG dye (0.2 - 0.5 mg/kg), SPY Imaging
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Georgetown University
Wounds, Chronic Wounds
Comparing the Clinical Outcomes of DermACELL® With Integra® Bilayer Wound Matrix
Both DermACELL® and Integra® Bilayer Wound Matrix are indicated for deep soft tissue coverage and serve as a biological matrix for cellular migration.
- Conditions
- Wounds, Chronic Wounds, Nonmalignant Condition
- Trial name
- NCT03285698
- Testing
- DermACELL®, Integra®
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Georgetown University
Advanced Solid Tumor Malignancies
PD-0332991, 5-FU, and Oxaliplatin for Advanced Solid Tumor Malignancies
This study is for patients with advanced solid tumor malignancies (cancer that has spread to other parts of the body). The purpose of this study is to test the safety and effectiveness of a new combination of drugs, PD-0332991…
- Trial name
- NCT01522989
- Testing
- PD-0332991, 5-FU, Oxaliplatin
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Georgetown University
Huntington Disease
Nilotinib in Huntington's Disease
Based on strong pre-clinical evidence of the effects of Nilotinib on neurodegenerative pathologies, including autophagic clearance of neurotoxic proteins, neurotransmitters (dopamine and glutamate), immunity and behavior, the…
- Trial name
- Tasigna HD (NCT03764215)
- Testing
- Nilotinib 150 MG
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Georgetown University
Desire to Avoid Pregnancy
Effectiveness and Efficacy of Dynamic Optimal Timing, a Smart Phone App for Avoiding Pregnancy: an Observational Study
The purpose of this study is to assess the effectiveness and efficacy of Dynamic Optimal Timing (DOT), an app-based method of family planning that can be used via Android devices, for women who use the method to avoid pregnancy.
- Trial name
- NCT02833922
- Testing
- Women using Dot to avoid pregnancy
- Volunteers
- 718 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Obesity, Childhood, Obesity, Adolescent
Cognitive Function and Body Mass Index in Children and Adolescents
The child will complete computerized tasks and paper-pencil test, and will be presented with symbols, letters, or numbers on a computer screen and asked to respond by pressing a button on the computer.
- Conditions
- Obesity, Childhood, Obesity, Adolescent, Cognitive Orientation
- Trial name
- NCT03963557
- Where
- United Arab Emirates
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Imperial College London Diabetes Centre
Breast Cancer, Obesity
Exergaming Intervention and Breast Cancer Biomarkers in Black Women
Overview: This is a 6 month, two-arm randomized clinical trial using comparing exergaming to a control group. The investigators will randomize Black sedentary overweight/obese women to Wii Fit exercise (n=50) or the control arm…
- Trial name
- POWER (NCT02152462)
- Testing
- Exergaming
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Proteinuria
A Crossover Pilot Study of the Effect of Amiloride on Proteinuria
This cross-over study is designed to test the hypothesis that amiloride will reduce urinary protein excretion and protect the kidney from rapid progression in proteinuric kidney disease.
- Trial name
- NCT02522650
- Testing
- Amiloride, Triamterene
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Georgetown University
Parental Infant Bonding, Cardio-respiratory Stability in Preterm NICU Infants
Effects of Reading to Preterm Infants on Baby and Parents' Well Being
Reading to children is believed to be beneficial to cognitive and mental development.This study will examine the response of premature Neonatal Intensive Care Unit (NICU) infants to bedside reading by measuring changes in heart…
- Trial name
- NCT02518997
- Testing
- Parental Reading Aloud
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Georgetown University
Breast Cancer
Effects of a Structured Exercise Program on Cancer-Related Fatigue in Women Receiving Radiation Therapy for Breast Cancer
Radiation therapy (RT) is often used to treat breast cancer. RT combined with breast surgery is associated with better outcomes in early stage breast cancer compared to surgery alone.
- Trial name
- NCT02117011
- Testing
- Physical Activity
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Georgetown University
Hepatocellular Carcinoma
Surefire Institutional DEB-TACE
The purpose of this study is to determine the feasibility and safety of the Surefire Infusion System (SIS) for delivery of Drug Eluting Beads Transcatheter Chemoembolization (DEB-TACE) in the HCC population.
- Trial name
- NCT03211598
- Testing
- TACE with Surefire
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Alexander Kim
Thymic Carcinoma, Thymus Neoplasms
Pembrolizumab and Epacadostat in Patients With Thymic Carcinoma
This is a non-randomized clinical trial in patients with thymic carcinomas who failed prior systemic therapy. All subjects will receive pembrolizumab and epacadostat treatment in three week cycles until unacceptable toxicity…
- Conditions
- Thymic Carcinoma, Thymus Neoplasms, Thymus Cancer
- Trial name
- NCT02364076
- Testing
- Pembrolizumab, Epacadostat
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Georgetown University