Clinical trials: sponsored by Emory University
Head and Neck Squamous Cell Carcinoma (HNSCC) - Recurrent/Metastatic (R/M)
A Phase II Trial for MOR Antagonism With Axelopran to Enhance Immunotherapy in Head and Neck Cancer
This Phase 2, open-label, multicenter study will evaluate the safety and preliminary efficacy of axelopran in combination with pembrolizumab in patients with PD-L1 positive recurrent or metastatic head and neck squamous cell…
- Trial name
- MORALE-HN01 (NCT07662720)
- Testing
- axelopran, Pembolizumab
- Volunteers
- 18 people
- Sponsor
- Glycyx Therapeutics
Physical Activity
Molecular Transducers of Physical Activity Consortium
The goal of the Molecular Transducers of Physical Activity Consortium (MoTrPAC) is to assess molecular changes that occur in response to physical activity (PA).
- Trial name
- MoTrPAC (NCT03960827)
- Testing
- EE Training, RE Training
- Where
- 11 sites in United States
- Volunteers
- 1,836 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Anxiety, PTSD
Temporal Interference in Psychiatry (TIP): Neuromodulation Using Temporal Interference
This study aims to understand the neural, behavioral and clinical effects of temporal interference (TI), a type of neuromodulation method, in healthy populations and in individuals with anxiety and stress-related conditions.
- Trial name
- NCT07558759
- Testing
- Electrical stimulation device
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Emory University
Bronchopulmonary Dysplasia
Pragmatic Research on Diuretic Management in Early BPD Pilot
Babies who are born prematurely often develop a chronic lung disease called bronchopulmonary dysplasia (BPD). BPD puts babies at higher risk for problems with growth and development.
- Trial name
- PRIMED (NCT05898022)
- Testing
- Furosemide (plus potassium chloride)
- Where
- 4 sites in United States
- Volunteers
- 19 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Physical Activity
Molecular Transducers of Physical Activity Consortium (MoTrPAC) - Pediatric Protocol
The goal of the Molecular Transducers of Physical Activity Consortium (MoTrPAC) is to assess molecular changes that occur in response to physical activity (PA).
- Trial name
- MoTrPAC (NCT04151199)
- Testing
- EE Training
- Where
- United States
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Prostate Carcinoma
An Investigational Scan (18F-rhPSMA-7.3 PET-mpMRI) for Targeted Prostate Biopsy Using TRUS-MR Fusion Technique
This phase II trial evaluates an imaging technique called 18F-rhPSMA-7.3 positron emission tomography (PET)-multiparametric (mp) magnetic resonance imaging (MRI) in identifying tumor tissue in men suspected to have prostate…
- Trial name
- NCT06865768
- Testing
- Flotufolastat F-18 Gallium, Magnetic Resonance Imaging, Multiparametric Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Emory University
Congenital Heart Disease
HFNC vs NIPPV Following Extubation
This study has the goal to determine the best method of respiratory support following extubation after cardiac surgery (CS). After cardiac surgery for Congenital Heart Disease (CHD), patients remain intubated until the cardiac…
- Trial name
- NCT05869825
- Testing
- High Flow Nasal Canula following extubation, Non-Invasive Positive Pressure Ventilation following extubation
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Emory University
AL Amyloidosis
Isatuximab as Upfront Therapy for the Treatment of High Risk AL Amyloidosis
This phase I trial studies the side effects of isatuximab and to see how well it works in treating patients with high risk immunoglobulin light chain amyloidosis (AL amyloidosis).
- Trial name
- NCT04754945
- Testing
- Bortezomib, Cyclophosphamide, Dexamethasone
- Where
- 6 sites in United States
- Volunteers
- 11 people
- Sponsor
- Emory University
Parkinson's Disease (PD), Alzheimer's Disease (AD) and Related Disorders
Moving Yourself in Space and Time: MYSTIC
This study is being done to answer the question: Do people with Parkinson's benefit from a new stepping therapy, and how do people with Parkinson's best learn new steps and rhythms set to music? Researchers will also compare…
- Conditions
- Parkinson's Disease (PD), Alzheimer's Disease (AD) and Related Disorders, Older Adults (60 - 85 Years Old)
- Trial name
- MYSTIC (NCT07697664)
- Testing
- Complex Rhythmic Movement Sequences (CRMS) Sessions
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Emory University
Lymphoma, Non-Hodgkin
Evaluation of Lymphoma Prognosis and Survivorship in Recently Diagnosed Patients, LEO Study
The goal of this infrastructure protocol is to build and maintain a large and diverse observational cohort study to support broad and cutting-edge research focused on NHL prognosis and survivorship.
- Trial name
- LEO (NCT04996706)
- Where
- 12 sites in United States
- Volunteers
- 21,000 people
- Sponsor
- Mayo Clinic
Alzheimer Disease
Georgia Memory Net Anti-Amyloid Monoclonal Antibody Registry
The purpose of this registry is to compile information on patients who are receiving FDA-approved anti-amyloid mAbs in the course of their clinic visits in the Emory Cognitive Neurology Clinic and in Georgia Memory Net Memory…
- Trial name
- NCT05999084
- Testing
- Anti-amyloid Monoclonal Antibodies (mAbs), Standard of Care
- Where
- 8 sites in United States
- Volunteers
- 735 people
- Sponsor
- Emory University
PTSD
MDMA Plus Exposure Therapy for PTSD
Posttraumatic stress disorder (PTSD) is a debilitating disorder. While effective treatments exist, some patients fail to receive the full benefits. Alternative treatment approaches are needed.
- Trial name
- NCT05746572
- Testing
- MDMA
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Emory University
Mild Cognitive Impairment
Voice Technology-Based Self-Management Intervention
This study aims to test a new technology-based program designed to help improve the ability to manage chronic conditions. This program includes daily smart speaker use for managing different tasks and technology learning.
- Trial name
- NCT06982261
- Testing
- Voice-activated smart speakers
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Emory University
Short Message Service (SMS), Incentives
Leveraging Community Health Workers and a Digital Health System to Improve the Timeliness of Child Well Visits
The goal of this cluster-randomized type 1 effectiveness implementation hybrid trial is to evaluate whether a community health worker led, integrated digital health intervention (Huduma Kwa Wakati; "Timely Services" in Kiswahili)…
- Conditions
- Short Message Service (SMS), Incentives, Knowledge, Attitudes, Practice, Preventive Services
- Trial name
- MINT-II/HKW (NCT06024317)
- Testing
- Huduma Kwa Wakati - Knowledge Intervention, Huduma Kwa Wakati - Reminders, Huduma Kwa Wakati - Incentives
- Where
- Tanzania
- Volunteers
- 800 people
- Sponsor
- University of South Carolina
Chronic Lymphocytic Leukemia, Diffuse Large B-Cell Lymphoma
Evaluation of Human Immune Responses Vaccination in Patients With Lymphoma
This clinical trial evaluates the influenza virus vaccination in evaluating human immune response in patients with lymphoma. Evaluating immune response may increase the understanding of how the immune system changes when patients…
- Conditions
- Chronic Lymphocytic Leukemia, Diffuse Large B-Cell Lymphoma, Follicular Lymphoma, Mantle Cell Lymphoma
- Trial name
- NCT03501576
- Testing
- Inactivated Influenza Vaccine
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Emory University
Diabetes
I Can Do This! Managing My Diabetes
The goals of this study are to: 1. Co-develop a user-friendly word game-based workbook format for patients with diabetes to understand how to manage their diabetes.
- Trial name
- NCT06695533
- Testing
- Diabetes self management workbook
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Emory University
Treatment Resistant Depression, Inflammation
Specialized Pro-resolving Lipid Mediators and Treatment Resistant Depression
The goal of this clinical trial is to determine the impact of omega-3 fatty acids on the production of anti-inflammatory effects and clinical improvement in people with depression who have not responded well to standard…
- Conditions
- Treatment Resistant Depression, Inflammation, Overweight
- Trial name
- NCT05774665
- Testing
- Omega 3
- Where
- 3 sites in United States
- Volunteers
- 14 people
- Sponsor
- Massachusetts General Hospital
Acute Respiratory Distress Syndrome, COVID-19
Trans Thoracic Manipulation of Ventilation/Perfusion: the V/Q System
The purpose of this pilot study is to measure the impact of non-invasive pneumatic manipulation of transthoracic pressure on oxygenation in patients with Acute Respiratory Distress Syndrome (ARDS) due to Coronavirus Disease 2019…
- Trial name
- NCT04369599
- Testing
- V/Q System
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Emory University
Ventricular Tachycardia
Ventricular Tachycardia Mechanisms
The purpose of this study is to understand why certain hearts have ventricular arrhythmias and help identify areas of the heart that cause arrhythmias.
- Trial name
- NCT05478213
- Testing
- Monophasic Action Potential (MAP) Catheter
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- Emory University
Cardiovascular Disease
Cardiology Biobank Registry
In the present study, investigators intend to establish a large database of cardiovascular patients. More specifically, investigators will create a database of approximately 12,000 cardiac catheterization and heart failure…
- Trial name
- NCT00378924
- Where
- United States
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Emory University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.