Clinical trials: not yet recruiting
Breast Cancer Surgery, Breast Cancer Surgery Pain
Impact of High Thoracic Paravertebral Block on Diaphragmatic Function: a Prospective Study
The high thoracic paravertebral block is a regional anesthesia technique commonly used for oncologic breast surgery. Local anesthetic is injected into the paravertebral space to provide anesthesia and pain relief.
- Conditions
- Breast Cancer Surgery, Breast Cancer Surgery Pain, Hemidiaphragmatic Paralysis
- Trial name
- NCT07907692
- Testing
- High thoracic paravertebral block
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Obesity
SYNCHRONIZE®-HERA: A Study to Test Whether Survodutide Helps Women Who Are Living With Overweight or Obesity and Are Going Through or Have Finished Menopause, to Lose Weight
This study is open to women up to 65 years of age who are living with overweight or obesity and are going through or have finished menopause.
- Trial name
- NCT07850050
- Testing
- Survodutide
- Where
- 16 sites in United States, United Kingdom
- Volunteers
- 600 people
- Sponsor
- Boehringer Ingelheim
Prostatectomy, Cystectomy
Hugo™ RAS Urology Post-Market Clinical Study
The purpose of this study is to collect evidence on the safety and performance of the Medtronic Hugo™ RAS System when used for urologic RAS procedures.
- Conditions
- Prostatectomy, Cystectomy, Nephrectomy, Urologic Cancer
- Trial name
- NCT07901049
- Testing
- Robotic Assisted Urologic Surgery
- Volunteers
- 110 people
- Sponsor
- Medtronic - MITG
Healthy
A Study to Test How Well Different Doses of BI 3821001 Are Tolerated by Healthy People
The main objectives of this trial are to investigate safety, tolerability and pharmacokinetics (PK) of BI 3821001 administrations of multiple rising doses.
- Trial name
- NCT07908004
- Testing
- BI 3821001
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Dyskinesia, Medication-induced, Dyskinesia, Drug-Induced
Safety and Tolerability of Single and Repeated Dose of IMM02-KORA in PD-associated Dyskinesia
The goal of this clinical trial is to test Safety and tolerability of single and repeated dose of IMM02-KORA in subjects with PD-associated dyskinesia.
- Trial name
- KORA-LID-1 (NCT07905976)
- Testing
- IMM02-KORA
- Volunteers
- 15 people
- Sponsor
- Immunis, Inc.
Irreversible Pulpitis, Anesthesia, Local
Cost-Effectiveness of Upfront Supplemental Anaesthesia in Symptomatic Irreversible Pulpitis
The goal of this clinical trial is to learn whether giving extra (supplemental) local anaesthetic injections at the start of treatment, rather than only after the standard injection fails, makes numbing of painful lower molar…
- Trial name
- UPFRONT-SIP (NCT07907120)
- Testing
- Inferior Alveolar Nerve Block With 2% Lidocaine With 1:80,000 Adrenaline, Upfront Buccal Infiltration With 4% Articaine With 1:100,000 Adrenaline, Upfront Intraligamentary Injection With 2% Lidocaine With 1:80,000 Adrenaline
- Where
- India
- Volunteers
- 234 people
- Sponsor
- Jamia Millia Islamia
Molar-Incisor Hypomineralization (MIH)
Clinical Performance of Glass Hybrid and Alkasite Restorative Systems in MIH-Affected Permanent First Molars
The purpose of this randomized clinical trial is to compare the clinical performance and survival of two restorative systems in permanent first molars affected by molar-incisor hypomineralization (MIH) in children aged 8 to 14…
- Trial name
- NCT07906548
- Testing
- Alkasite Restorative System, Glass Hybrid Restorative System
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Çanakkale Onsekiz Mart University
Chronic Obstructive Pulmonary Disease, Lung Diseases, Obstructive
Impact of Multidisciplinary Care, Structured and Targeted on the COPD Patient's Clinical Pathway.
In 2020, chronic obstructive pulmonary disease (COPD) was the 4th leading cause of death worldwide. In France, its annual cost was estimated at 4366 euros per patient, including 25% related to management of exacerbations and 33%…
- Conditions
- Chronic Obstructive Pulmonary Disease, Lung Diseases, Obstructive, Lung Disease Chronic
- Trial name
- OPTI-BPCO (NCT07907601)
- Testing
- COPD targeted pharmaceutical interview and consultation, Respiratory Insufficiency Day Hospitalization, Pulmonary Function Test
- Where
- France
- Volunteers
- 116 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Prostate Biopsy
A Multicenter, Randomized Controlled Superiority Trial Comparing Robotic-Assisted Versus Expert Cognitive Fusion Prostate Biopsy in Obese Men
The trial aims to find out if using a robotic system to help perform prostate biopsies is better than having a highly experienced doctor perform the biopsy by hand in men with a high Body Mass Index (BMI).
- Trial name
- NCT07600216
- Testing
- Robotic-Assisted Fusion Biopsy, Expert Cognitive Fusion Biopsy
- Where
- China
- Volunteers
- 570 people
- Sponsor
- Shanghai East Hospital
Lactate
Evaluate Precision of the Test for Lactate in Capillary Whole Blood Specimens Using the i-STAT CG4+ Cartridge With the i-STAT 1 Analyzer
Assess precision of the i-STAT lactate test with the i-STAT CG4+ cartridge on the i-STAT 1 analyzer using two (2) separate capillary blood specimens.
- Trial name
- NCT07908056
- Testing
- Fingerstick capillary blood draw
- Where
- 3 sites in United States
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- Abbott Point of Care
Skin Lesions
Human-AI Uncertainty Callibration for Improved Skin Lesion Segmentation
The goal of this randomized controlled study is to compare the effect of a new, personalized uncertainty-aware decision model (FDM) to a standard image recognition model in improving the diagnostic accuracy while reducing…
- Trial name
- NCT07468357
- Testing
- Base Model, FDM
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Stroke, Acute Ischemic, Medium Vessel Occlusion
INTRA-ARTERIAL MeVO TREATMENT (IMP-ACT) Within the ACT-GLOBAL Adaptive Platform Trial-NCT06352632
This domain will be conducted as part of ACT-GLOBAL platform trial and will have the nested domain name of IMP-ACT. Acute ischemic stroke (AIS) caused by intracranial arterial occlusion remains a major cause of disability and…
- Trial name
- IMP-ACT (NCT07906275)
- Testing
- Mechanical Endovascular Thrombectomy, Intravenous Thrombolysis, Tenecteplase/Alteplase- depending upon availability at each treating centre
- Where
- 4 sites in Canada
- Volunteers
- 800 people
- Sponsor
- University of Calgary
PSMA Positive Tumors or Tumor Tissues
PSMA-specific CAR-T Cell Therapy
The purpose of this clinical trial is to assess the feasibility, safety and efficacy of PSMA-specific CAR-T cell therapy in patients with PSMA positive tumor.
- Trial name
- NCT04429451
- Testing
- 4SCAR-PSMA T cells
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shenzhen Geno-Immune Medical Institute
Primary Biliary Cholangitis (PBC)
A Study of Fatigue, Itching and Daily Activities in People With Primary Biliary Cholangitis Starting Elafibranor
The purpose of this study is to understand how tiredness changes in adults with Primary Biliary Cholangitis (PBC) after starting elafibranor in routine clinical practice.
- Trial name
- NCT07906639
- Testing
- Elafibranor
- Volunteers
- 50 people
- Sponsor
- Ipsen
COVID - 19, Long COVID Syndrome
Dapagliflozin for Long COVID Syndrome
This is a randomized, placebo-controlled study. Patients with long COVID will be randomized to receive dapagliflozin or placebo for 12 months.
- Conditions
- COVID - 19, Long COVID Syndrome, SARS CoV-2
- Trial name
- DALCO (NCT06907251)
- Testing
- Dapagliflozin (DAPA)
- Where
- Canada
- Volunteers
- 192 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Shoulder
Methylprednisolone Taper is an Effective Addition to Multimodal Pain Regimens After Rotator Cuff Repair
The use of Methylprednisolone Taper will be investigated in the setting of a Rotator Cuff Repair to determine if it will result in lower pain levels following surgery
- Trial name
- NCT07902843
- Testing
- Methylprednisolone taper
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The Hawkins Foundation
Alcohol, Cannabis
A Hybrid Type 1 Randomized Controlled Trial of an Online and Text-Messaging Intervention to Prevent Alcohol and Cannabis Initiation, Escalation, and Consequences Among First-Year College Students
Building on promising pilot findings, this study will employ a Hybrid Type 1 Effectiveness-Implementation RCT to evaluate the effectiveness of a novel intervention for first-year college students who abstain from or use alcohol…
- Trial name
- NCT07905846
- Testing
- Online and Text Message Intervention
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Epilepsy
Lily's Grace Temporal Interference
This study is to evaluate the effectiveness of targeted Transcranial Electrical Stimulation with Temporal Interference (TES-TI) interventions to boost Non-Rapid Eye Movement (NREM) sleep, decrease seizures and promote emotional…
- Trial name
- SLEEP-TIES (NCT07520955)
- Testing
- TES-TI, Structural and Functional MRI
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Wisconsin, Madison
Helicobacter Pylori
Pilot Study of a Gastric String Test Combined With a Rapid Antigen Assay for Helicobacter Pylori Detection
This single-center, open-label, prospective pilot study aims to evaluate the feasibility, safety, and preliminary diagnostic performance of a minimally invasive gastric string sampling device combined with a rapid antigen assay…
- Trial name
- NCT07906938
- Testing
- HP String Test With Rapid Antigen Assay
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fu Jen Catholic University Hospital
Cervical Radiculopathy
Ultrasound-Guided Electrical Dry Needling for Chronic Cervical Radiculopathy: A Randomized Controlled Trial
This randomized controlled trial aims to investigate whether ultrasound-guided electrical dry needling with conventional physical therapy is more effective than conventional physical therapy alone in the following outcome…
- Trial name
- NCT07907562
- Testing
- Ultrasound-guided electrical dry needling, Conventional Physical Therapy
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Liberty University
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