Clinical trials: not yet recruiting
Breast Ductal Carcinoma In Situ, Hematopoietic and Lymphatic System Neoplasm
Addressing Financial Hardship in AYA Cancer Survivors Through the Use of the New LIFT UP Intervention
This clinical trial addresses the financial hardship among adolescent and young adult (AYA) survivors using the new Lessening the Impact of Financial Toxicity (LIFT) UP intervention.
- Conditions
- Breast Ductal Carcinoma In Situ, Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT07909525
- Testing
- Best Practice, Educational Intervention, Informational Intervention
- Volunteers
- 448 people
- Sponsor
- ECOG-ACRIN Cancer Research Group
Chronic Kidney Disease, Sarcopenia
Sarcopenia in Chronic Kidney Disease (CKD) Patients
Sarcopenia, or loss of muscle and strength is common in patients with poor kidney function. Although a high protein diet is generally recommended for sarcopenia, patients with poor kidney function are advised to follow a…
- Trial name
- BOOST_CKD (NCT07437053)
- Testing
- Valine, EEA
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Head & Neck Cancer
Gut-Liver-Muscle Axis in Cancer Cachexia
The purpose of this study is to determine if consuming a nutritional supplement before surgery affects weight loss, inflammation, and muscle in people with head and neck cancer cachexia.
- Trial name
- NCT07911150
- Testing
- Impact Advanced Recovery (Impact AR), Boost® High Protein + Beneprotein®
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Colorado, Denver
Food Choices
Environmental Harm Menu Labels and the Healthfulness of Real-World Fast-Food Orders
The primary objective of this study is to evaluate whether repeated exposure to environmental harm menu labels on fast-food restaurant menus improves the healthfulness of real-world fast-food meal orders.
- Trial name
- MENU (NCT07910604)
- Testing
- Control (QR Code) Menu Labels, Traffic-Light Style Environmental Harm Menu Labels
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Postoperative Pain
ESP Versus SPSIP Block for Pain Relief After Shoulder Arthroscopy
This study will compare two regional anesthesia techniques for pain relief after arthroscopic shoulder surgery: high thoracic erector spinae plane (ESP) block and serratus posterior superior intercostal plane (SPSIP) block.
- Trial name
- ESP-SPSIP (NCT07906392)
- Testing
- High Thoracic Erector Spinae Plane Block, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ferit Yetik
Hypertension (HTN), Blood Pressure
Team-Based Shared Decision-Making Program in Hypertension Control (Healthy Heart - BP Program)
The main goal of the study is to conduct a pilot trial to test the feasibility of the Team-Based Shared Decision-Making (SDM) Program, supported by Healthy Heart, involving 90 adults with uncontrolled hypertension (HTN) at…
- Trial name
- SDM in BP (NCT07909161)
- Testing
- Pharmacist-led Team-Based SDM on health behavior change and medication management for HTN control, Nurse-led Team-Based SDM on health behavior change and medication management for HTN control, Telehealth SDM visits focus on medication management and health behavior change
- Volunteers
- 90 people
- Sponsor
- Johns Hopkins University
Healthy Participants
A Trial to Assess the Relative Bioavailability of Different Subcutaneous Formulations of AZD9550 and AZD6234
This study in healthy volunteers aims to compare blood levels and side effects after administration of different formulations of two test medicines, AZD9550 and AZD6234.
- Trial name
- NCT07911514
- Testing
- AZD9550 solution for injection, AZD6234 solution for injection, Formulation 1 solution for injection
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Lateral Epicondylitis, Medial Epicondylitis
Investigation of Obsessive-Compulsive Disorder in Patients With Elbow Epicondylitis
This study will compare obsessive-compulsive symptoms in adults with medial and/or lateral elbow epicondylitis (pain and tenderness on the inner and/or outer side of the elbow).
- Conditions
- Lateral Epicondylitis, Medial Epicondylitis, Obsessive-Compulsive Symptoms
- Trial name
- NCT07906379
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Fatih Turkmensoy
Recurrent Glioblastoma
Safety and Efficacy of Autologous Natural Killer Cell Therapy (CHANK-101) in Patients With Recurrent Glioblastoma
This multicenter, open-label, externally controlled clinical study is designed to evaluate the safety and efficacy of CHANK-101, an autologous natural killer (NK) cell therapy, in patients with recurrent glioblastoma.
- Trial name
- NCT07831161
- Testing
- CHANK-101
- Where
- 4 sites in South Korea
- Volunteers
- 60 people
- Sponsor
- Dong-A University Hospital
Gait Balance
EVS With Exercise for Balance With Older Adults
This study will test whether electrical stimulation of the balance system adds benefit to an exercise program for adults aged 60 years and older. The treatment is called noisy electrical vestibular stimulation (nEVS).
- Trial name
- NCT07890623
- Testing
- Noisy electrical vestibular stimulation
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Glioblastoma of Cerebellum
DLL3 CAR-T Therapy Targeting Brain Tumors
The purpose of this study is to assess the feasibility, safety and efficacy of Delta-like ligand 3 (DLL3)-specific CAR-T cell therapy in patients with DLL3 positive brain tumors including glioblastomas and diffused intrinsic…
- Trial name
- NCT07180927
- Testing
- 4SCAR DLL3 T cells
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shenzhen Geno-Immune Medical Institute
Cardiovascular-kidney-metabolic Syndrome, Diabete Type 2
SWitching to Appropriate Prescription in Cardiovascular-Kidney-Metabolic Syndrome
SWAP-CKM (SWitching to Appropriate Prescription in Cardiovascular-Kidney-Metabolic Syndrome) is a pragmatic, cluster-randomized clinical trial designed to evaluate whether electronic health record (EHR)-based alerts can improve…
- Conditions
- Cardiovascular-kidney-metabolic Syndrome, Diabete Type 2, Chronic Kidney Disease, Heart Failure
- Trial name
- SWAP-CKM (NCT07910968)
- Testing
- Real-Time EHR Prompts and Audit-and-Feedback Reports
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Kaiser Permanente
Biliary Tract Cancer (BTC)
Prospective AI-Assisted Screening of Biliary Tract Cancer Using Non-Contrast CT
Biliary tract cancer is a group of malignant tumors involving the intrahepatic bile ducts, extrahepatic bile ducts, and gallbladder.
- Trial name
- BTC-NCCT-AI (NCT07911397)
- Testing
- AI-Assisted Biliary Tract Cancer Screening Using NCCT
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Localized Prostate Cancer
WATER IV PCa (AS Sub-study)
The WATER IV study is a multicenter, prospective, randomized clinical trial that aims to evaluate the safety and efficacy of Aquablation therapy in men with localized prostate cancer.
- Trial name
- NCT07650448
- Testing
- Aquablation Therapy, Active Surveillance
- Where
- 27 sites in United States, Hong Kong
- Volunteers
- 333 people
- Sponsor
- PROCEPT BioRobotics
Chronic Pain, Sickle Cell Disease
Focused Ultrasound Neuromodulation for Chronic Pain
This study will evaluate the feasibility, tolerability, and preliminary analgesic effects of individualized Precision Confidence Mapping-guided low-intensity focused ultrasound neuromodulation in adults with chronic pain.
- Conditions
- Chronic Pain, Sickle Cell Disease, Chronic Pelvic Pain Syndrome
- Trial name
- NCT07910396
- Testing
- Focused PCM-Guided CMN LIFU, Unfocused Control LIFU
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Minnesota
Vestibulodynia, Vulvodynia
Integrated Care Pathway for Hormonally Mediated Vestibulodynia: a Feasibility and Acceptability Pilot
This single-arm pilot study evaluates whether an integrated six-month care pathway for women with persistent vestibular vulvar pain and suspected hormonally mediated vestibulodynia can be delivered as planned, and how…
- Conditions
- Vestibulodynia, Vulvodynia, Vulvar Vestibulitis
- Trial name
- HerAccess (NCT07908901)
- Testing
- HerAccess integrated care pathway
- Where
- 2 sites in Denmark
- Volunteers
- 35 people
- Sponsor
- HerAccess ApS
Metastatic Colorectal Cancer
Real-World Treatment Patterns and Effectiveness of Anti-EGFR- and Anti-VEGF-based Therapies in Left-sided RAS Wild-Type Metastatic Colorectal Cancer
The aim of this study is to learn how doctors treat a type of metastatic colorectal cancer in everyday medical practice. The study focuses on patients whose cancer started on the left side of the colon and does not have specific…
- Trial name
- NCT07909122
- Testing
- Anti-EGFR-Based Therapy, Anti-VEGF-Based Therapy
- Volunteers
- 1 people
- Sponsor
- Pfizer
Cardiotoxicity, Cancer
Monitoring for CardioToxicity Using WeArable deVices While Undergoing cancEr Treatments (MCT-WAVE)
This pilot study will evaluate the validity and feasibility of ambulatory cardiac monitoring to identify markers of cardiotoxicity in adults undergoing cancer treatment.
- Conditions
- Cardiotoxicity, Cancer, Cardiac Arrhythmia, Left Ventricular Dysfunction
- Trial name
- NCT07776964
- Testing
- Mobile Cardiac Telemetry, Wearable Cardiac Monitor
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Minnesota
Obesity (Disorder), Inflammation
Effects of Taurine Supplementation and Morning or Evening High-intensity Exercise on Circadian Clock Genes and Inflammatory Parameters in Adult Women With Obesity
The goal of this clinical trial is to evaluate whether taurine supplementation, alone or combined with high-intensity interval training (HIIT) performed in morning or evening, affects circadian clock gene expression and…
- Trial name
- NCT07910747
- Testing
- Taurine supplementation, High-intensity interval training (HIIT)
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Mantle Cell Lymphoma
Polatuzumab Vedotin, Mosunetuzumab, and Acalabrutinib for the Treatment of Mantle Cell Lymphoma, PAcMan Trial
This phase II trial tests how well polatuzumab vedotin, mosunetuzumab, and acalabrutinib work in treating patients with mantle cell lymphoma.
- Trial name
- NCT07910435
- Testing
- Polatuzumab Vedotin, Acalabrutinib, Mosunetuzumab
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Washington
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