Clinical trials: Phase not applicable, completed
Fibromyalgia, Pregabalin
The Efficacy and Safety of Short Term S-ketamine Infusion as an Adjunctive Therapy in Patients With Fibromyalgia
Fibromyalgia is a chronic pain syndrome where current medications have limited efficacy and a slow onset of action. Esketamine shows potential as a rapid-acting analgesic, but previous low-dose studies failed to demonstrate…
- Conditions
- Fibromyalgia, Pregabalin, Esketamine
- Trial name
- NCT07230171
- Testing
- Pregabalin and venlafaxine concomitant therapy, Esketamine plus pregabalin and venlafaxine concomitant therapy
- Where
- China
- Volunteers
- 92 people
- Sponsor
- Beijing Tiantan Hospital
Occupational Diseases, Neck Pain
Effectiveness of Pilates Exercises Applied to Violinists With Nonspecific Neck Pain
Nonspecific neck pain is common among violinists because of the sustained asymmetric posture required to hold the instrument. This randomized controlled trial compared the effects of a 12-week Mat Pilates program with a 12-week…
- Trial name
- NCT06843759
- Testing
- mat pilates, reformer pilates
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Uskudar University
Acute Pain, Anxiety
The Effect of ShotBlocker on Pain, Anxiety, and Satisfaction During Peripheral Intravenous Catheterization
This randomized controlled trial aims to evaluate the effect of the ShotBlocker device on pain, anxiety, and patient satisfaction during peripheral intravenous catheterization (PIVC).
- Trial name
- SB-PIVC (NCT07553624)
- Testing
- ShotBlocker
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Down Syndrome (DS), Supplementation
Effects of Chronic Creatine and Beta-Hydroxy-Beta-Methylbutyrate Supplementation on Oxidative Stress, Inflammation, Muscle Strength, and Body Composition in Individuals With Down Syndrome
Purpose: This study will test whether 8 weeks of creatine and HMB supplementation can improve muscle strength, body composition, balance, and overall health in people with Down syndrome.
- Trial name
- NCT07213063
- Testing
- Nutrition education, Supplement
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Universidad de Burgos
Fecal Incontinence
Safety and Performance of a Silicone Implant for Fecal Incontinence Treatment (SimplyFI)
The purpose of the clinical investigation is to verify that the device under investigation (SimplyFI) is appropriate to significantly improve fecal incontinence in patients in whom its use is indicated.
- Trial name
- NCT05708612
- Testing
- Medical Device (SimplyFI)
- Where
- 5 sites in Austria, Germany and 1 more
- Volunteers
- 43 people
- Sponsor
- A.M.I. Agency for Medical Innovations GmbH
Asthma in Children
Evaluation of the Asthma Management Program to Promote Activity for Students in Schools (Asthma-PASS)
Physical activity (PA) is an important component of asthma management in children. Studies show that PA is associated with decreased severity of asthma symptoms, as well as improved disease control and quality of life.
- Trial name
- NCT04576442
- Testing
- Asthma-PASS, Basic Asthma Management (AM), Child/Caregiver Education session
- Where
- United States
- Volunteers
- 452 people
- Sponsor
- Montefiore Medical Center
Burn Injury
Exercise in Burn Survivors: Cooling Modalities
This project will identify the efficacy of cooling modalities aimed to attenuate excessive elevations in skin and internal body temperatures during physical activity in well-healed burn survivors.
- Trial name
- NCT04512976
- Testing
- Control (no cooling modalities), Water Spray Only, Fan Only
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Persistent Atrial Fibrillation, Pulsed-field Ablation
Pulsed-field Ablation in Patients With Persistent Atrial Fibrillation
Since a new method called pulsed-field ablation (PFA) has emerged, allowing significantly simpler, safer, and faster creation of ablative lesions in paroxysmal AF and PsAF (13), redefining the "optimal" ablation approach started…
- Trial name
- PIVCO (NCT05922917)
- Testing
- pulsed-field ablation
- Where
- 3 sites in Czechia
- Volunteers
- 518 people
- Sponsor
- České Budějovice Hospital
Anastomotic Leak, Bowel Resection
Intra-Operative Infrared Thermography for Bowel Resection
This prospective randomized control pilot study evaluates the use of intra-operative infrared thermography compared to conventional visual assessment for preventing anastomotic leaks in bowel resection surgeries.
- Conditions
- Anastomotic Leak, Bowel Resection, Intestinal Ischemia
- Trial name
- NCT07906704
- Testing
- Intra-operative Infrared Thermography, Conventional visual assessment
- Where
- India
- Volunteers
- 80 people
- Sponsor
- Sir Ganga Ram Hospital
Oral Festination, Lingual Pumping
The Effect of an Auditory Rhythmic Cue on the Frequency of Rolling in Patients With Dysphagia and Parkinson's Disease
The main objective of this clinical study is to measure the effect of rhythmic auditory cueing, introduced in rehabilitation with three weekly sessions over a period of 7 weeks, on the frequency of rolling in idiopathic…
- Conditions
- Oral Festination, Lingual Pumping, Dysphagia, Swallowing Disorder
- Trial name
- Rhythm'nRoll (NCT06695455)
- Testing
- Swallowing rehabilitation by rhythmic auditory cue
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Hopital La Musse
Neck Pain, Signs and Symptoms
The Effect of Tecar Therapy in Patients With Chronic Neck Pain
Neck pain is a highly prevalent musculoskeletal disorder. Alongside pharmacological treatments, evidence supports the efficacy of physical therapy modalities and exercise in managing chronic neck pain.
- Conditions
- Neck Pain, Signs and Symptoms, Disability Physical
- Trial name
- NCT07907874
- Testing
- Tecar therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Ankara City Hospital Bilkent
Choledocholithiasis
Detection of Residual Bile Duct Stones by Cholangioscopy After Negative ERCP Cholangiography and Interobserver Agreement: A Self-Controlled Study
Common bile duct stones (CBDS) are a common biliary disorder, and endoscopic retrograde cholangiopancreatography (ERCP) is currently the primary minimally invasive approach for their diagnosis and treatment.
- Trial name
- NCT07906782
- Testing
- Peroral Cholangioscopy
- Where
- China
- Volunteers
- 31 people
- Sponsor
- First People's Hospital of Hangzhou
Hemiplegic Shoulder Pain
Comparison of Effectiveness of Low Dose Laser and Transcutaneous Electrical Stimulation in Hemiplegic Shoulder
The primary aim of this study is to compare the efficacy of Transcutaneous Electrical Nerve Stimulation (TENS) and Low Level Laser Therapy (LLLT), which are analgesic modalities that play an important role in the treatment of…
- Trial name
- NCT07203222
- Testing
- Low Dose Laser, TENS, Conventional physical therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ankara Etlik City Hospital
Mind Mapping, Nursing Students
Mind Mapping: Impact on Critical Thinking and Problem-Solving Skills
This randomized controlled trial aims to evaluate the effectiveness of the mind mapping method in enhancing critical thinking and problem-solving skills among nursing students.
- Conditions
- Mind Mapping, Nursing Students, Critical Thinking
- Trial name
- Mind mapping (NCT07548658)
- Testing
- Mind mapping
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Gazi University
Pulmonary Hypertension, Heart Failure
Study for Evaluation of Safety and Efficacy of PADN to Treat Combined Post- and Pre- Capillary Pulmonary Hypertension Associated With Chronic Heart Failure（PADN-CpcPH-PILOT）
The goal of this pilot study is to evaluate the safety and efficacy of pulmonary artery denervation (PADN) in Combined Post- and Pre- Capillary Pulmonary Hypertension Associated with Chronic Heart Failure.
- Trial name
- NCT05996562
- Testing
- Pulmonary Artery Denervation
- Where
- 7 sites in Georgia, Italy and 3 more
- Volunteers
- 30 people
- Sponsor
- Pulnovo Medical (Wuxi) Co., Ltd.
Mechanical Ventilation, Fluid Overload
Lung Ultrasound-Guided Fluid Deresuscitation in ICU Patients
Timely recognition and treatment of fluid overload can expedite liberation from invasive mechanical ventilation in intensive care unit (ICU) patients.
- Conditions
- Mechanical Ventilation, Fluid Overload, Deresuscitation, Ventilator-free Days
- Trial name
- CONFIDENCE (NCT05188092)
- Testing
- Lung ultrasound guided deresuscitation
- Where
- 3 sites in Netherlands
- Volunteers
- 998 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Orthodontic Aligners
The Efficiency of Clear Aligners in Maxillary Molar Distalization: A Randomized Clinical Trial.
The aim of this study is to evaluate the accuracy of clear aligners on the amount of the maxillary molar distalization.
- Trial name
- Aligner (NCT06330571)
- Testing
- Molar distalization by aligners with attachment
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Flexor Hallucis Longus Muscle Strength in Elderly Individuals
Flexor Hallucis Longus Training and Balance-Gait in Geriatrics
Examination of Balance-Gait Parameters and Fall Effect of Flexor Hallucis Longus Muscle Strengthening Training in Geriatric Group It has been demonstrated that the reduction in the strength of the toe flexor muscles is an…
- Trial name
- NCT06887478
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Lokman Hekim University
Caregiver Stress
STRIDE: Stress Reduction in Dementia Caregivers
The investigators aim to conduct a feasibility, proof of concept randomized controlled trial (RCT) of a smartphone app intervention (Healthy Minds Program; HMP) versus Wellness app (WA) among heterogeneous stressed caregivers of…
- Trial name
- NCT05732038
- Testing
- Healthy Minds Program (HMP), Wellness App (WA)
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Massachusetts General Hospital
Cervical Disc Herniation
The Effects of CSE and ISE on Pain, Strength, Flexibility, Disability and QoL in Patients With CDH
Cervical disc herniation is a common source of cervical radiculopathy, which can occur suddenly due to trauma and results from chemical and mechanical degenerative changes that occur over time, with an annual incidence of 1.6 per…
- Trial name
- NCT06098365
- Testing
- segmental cervical stabilization exercises, cervical isometric exercises
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Uskudar University