Clinical trials: sponsored by University Hospital, Limoges
Ventilator Acquired Pneumonia, Mechanical Ventilation Complication
ClusterVAP: Multicentre Proteomic Endotyping of Ventilator-associated Pneumonia
Ventilator-associated pneumonia (VAP) is a common and serious infection in patients receiving mechanical ventilation in intensive care units.
- Trial name
- ClusterVAP (NCT07245888)
- Where
- 4 sites in France, Portugal and 1 more
- Volunteers
- 400 people
- Sponsor
- Region Skane
Infection, COVID-19
COVID 19-Caregivers IGg Seroconversion
According to recent publications, the percentage of caregivers infected with COVID 19 is evaluated between 10 and 30% . This great variability is due, on the one hand to the intensity of the influx of covid plus patients and, on…
- Trial name
- CoSigS (NCT04353323)
- Testing
- Blood sampling
- Where
- France
- Sponsor
- University Hospital, Limoges
Hematologic Cancer
The Point of View of Hematological Cancer Patients and Their Loved Ones Regarding Spirituality
The management of patients with malignant hemopathy is based on comprehensive management. In this context and faced with the various difficulties encountered by cancer patients, the question of spirituality and its experience is…
- Trial name
- SPIRIHEMATO (NCT04412135)
- Testing
- spirituality
- Sponsor
- University Hospital, Limoges
Colorectal Cancer
Use of Alternative and Complementary Medicine by Colorectal Cancer Patients
Complementary and alternative medicine (CAM) is defined by the National Center for Complementary and Alternative Medicine as "a group of diverse medical and health systems, practices and products that are not currently considered…
- Trial name
- ALTERNATIVCCR (NCT06779669)
- Testing
- Questionnaire CAM
- Where
- France
- Volunteers
- 217 people
- Sponsor
- University Hospital, Limoges
Organ Transplantation
Optimizing Long-term Survival in Organ Transplantation: From Physiopathology to Optimized Patient Management
Increased indications for transplantation continue to worsen the shortage of organs and need the extension of graft sampling criteria and the search for new potential sources of organs.
- Trial name
- BIOSUPORT (NCT03997253)
- Testing
- blood and urine samples
- Where
- 4 sites in France
- Volunteers
- 430 people
- Sponsor
- University Hospital, Limoges
Obesity
Childhood Traumas in Obese Women: Association With Deregulation of the Glucocorticoid Axis and Inflammatory State.
We postulate that childhood traumas are associated with deregulation of the glucocorticoid axis and the inflammatory system in obese women.
- Trial name
- OBEVIE (NCT05237440)
- Testing
- Biological dosage
- Where
- France
- Volunteers
- 102 people
- Sponsor
- University Hospital, Limoges
SARS-CoV2 Infection
Remote Assessment of Outpatient With Severe Acute Respiratory Syndrome (SARS-CoV-2)
Outpatient management of patients with a milder form of COVID may be associated to an unfavorable initial or deferred course in relation to the pathology.. Outpatients represent the bulk of patients with COVID-19.
- Trial name
- EVIDENCE (NCT05125887)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 92 people
- Sponsor
- University Hospital, Limoges
Disablement in the Elderly
Home-Based Technologies Coupled to Teleassistance Service in the Elderly
The growth of the elderly population is associated with the autonomy failure and the increase of dependence problems. Fall incidents are the third cause of chronic disablement in older persons and are one of the major risk…
- Trial name
- DOMOLIM (NCT01697553)
- Testing
- home automation pack coupled to teleassistance service, Home without automation pack coupled to teleassistance service
- Where
- 4 sites in France
- Volunteers
- 27 people
- Sponsor
- University Hospital, Limoges
Brain Injuries
Cognitive Assessment by the Mean of Event Related Potentials
The main objective of this study is to describe differential cognitive processing of various stimuli by a population of control subjects and a population of patients with selective cognitive deficits or altered states of…
- Trial name
- PEC (NCT01899924)
- Testing
- Event Related Potentials recording
- Where
- France
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Giant Cell Arteritis
Giant Cell Arteritis: Comparison Between Two Standardized Corticosteroids Tapering
Corticosteroid therapy has always been the standard treatment for giant cell arteritis (GCA), with very good initial clinical efficacy but a high relapse rate when it declines.
- Trial name
- CORTODOSE (NCT04012905)
- Testing
- Corticosteroids for Systemic Use
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Caen
Cerebral Arterio-venous Malformation
Impact of CErebral Endovascular PROcedures on the Systemic Immune responSe Response
In our ICU, it could notice that patients with cerebral arterio-venous malformation (AVM) treated with embolization develop more severe Ventilator Associated Pneumoniae (VAP) compare to other patients hospitalized for…
- Trial name
- PROCESS (NCT05621850)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 78 people
- Sponsor
- University Hospital, Limoges
Amyotrophic Lateral Sclerosis
Staging System in Amyotrophic Lateral Sclerosis
Recently two staging systems have been proposed for amyotrophic lateral sclerosis (ALS), based on clinical milestones The King's college clinical staging system (1) and ALS Milano-Torino Staging (ALS-MITOS) (2).
- Trial name
- Biostaging (NCT04858555)
- Where
- 2 sites in France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Limoges
Multiple Sclerosis
Effects of A Dual-Task Intervention in Postural Control in Multiple Sclerosis Patients
Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease affecting the central nervous system. It is the leading cause of severe non-traumatic disability in young adults (20-40 years).
- Trial name
- MOCOGSEP (NCT04090996)
- Testing
- Dual TAsk
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Hematological Diseases
Secure Outsourcing of Carfilzomib in the Treatment of Multiple Myeloma to the Hospital at Home Setting
Since 2009, the Department of Clinical Haematology at Limoges University Hospital Centre, supported by the HEMATOLIM network, has been operating the regional "ESCADHEM" system: [Secure outsourcing of injectable chemotherapy to…
- Trial name
- Carfil-HAD (NCT05041933)
- Testing
- outsourcing of chemotherapy to Hospital at Home
- Where
- France
- Volunteers
- 17 people
- Sponsor
- University Hospital, Limoges
Choroidal Neovascularization, Visual Field, Visual Acuity
OCT and Microperimetry in Patients With Active Neovascular ARMD (CORFI)
ARMD is the main cause of visual disability after 50 years old in France. Patients with active neovascular ARMD are treated with intravitreal injections of antiVEGF.
- Trial name
- CORFI (NCT03435926)
- Where
- France
- Sponsor
- University Hospital, Limoges
Viral Infection, Sepsis
COMPArative Study of the Consequence on innaTe Immune Response du to Bacterial or Viral Infection in Patients Admitted to Intensive Care Unit
Patient admitted in intensive care unit (ICU) for acute infection whether it be viral or bacterial had major impairment of the immune response.
- Trial name
- COMPACT (NCT05671159)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 38 people
- Sponsor
- University Hospital, Limoges
Hepatitis B Virus
NK Cell Deregulation in HBV Patients
Natural Killer (NK) cells play a large role in the innate immune response as they are equipped to kill infected or tumor cells. They express a panel of activating and inhibitory receptors that regulate the destruction of the…
- Trial name
- LiNKeB (NCT03761875)
- Testing
- blood sample CHB patients, boold sample Control group
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Infection Viral
COVID-19 Serological Status of Hospital Staff Working or Not in the COVID-19 Sector
Hospital staff, on the front line in the COVID-19 crisis, have many questions about the risk that they have been infected with this potentially fatal virus.
- Trial name
- SEROCO (NCT04481529)
- Testing
- Health Questionnaire
- Where
- 4 sites in France
- Volunteers
- 1,576 people
- Sponsor
- University Hospital, Limoges
COVID-19
Pulmonary Function in Patients Recovering From COVID19 Infection : a Pilot Study
The current state of knowledge shows the presence of respiratory sequelae after acute infection with COVID-19 and the importance of these long-term respiratory dysfunctions have to be determined.
- Trial name
- EFRUPIC (NCT05074927)
- Testing
- diaphragm ultrasonography
- Where
- 2 sites in France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Limoges
Medical Oncology, Hematology
Onco-haematology Vigilance Card
The objective of this study is to show the interest of setting up a drug vigilance card in Oncology in order to reinforce patient safety, develop compliance and avoid drug interactions when the patient consults town professionals…
- Conditions
- Medical Oncology, Hematology, Molecular Targeted Therapies
- Trial name
- THERANOVA-LIM (NCT04931329)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Limoges