Clinical trials: sponsored by Al-Azhar University
Role of Neurofilment in Diagnosis of Multiple Sclerosis
Neurofilament Light Chain as Diagnostic and Prognostic Marker in naïve Multiple Sclerosis Patients
Neurofilament protein detected in the serum appears to be a good marker for the extent of active neurodegeneration. Chitinase may also be a good marker reflecting the degree of astrocyte activation, or damage in active lesions…
- Trial name
- NFLMS (NCT06197841)
- Where
- Egypt
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Assiut University
Retinal Detachment
Evaluation of Vitrectomy With ILM Peeling in Myopic Macular Hole With Only Posterior Retinal Detachment
Retinal detachment (RD) resulting from the macular hole (MH), also known as MH-induced RD (MHRD), most commonly occurs in eyes with high myopia and results in irreversible visual disorders.
- Trial name
- NCT06194760
- Testing
- Vitrectomy with ILM peeling
- Where
- Egypt
- Volunteers
- 13 people
- Sponsor
- Al-Azhar University
Shoulder Injuries
Results of Distal Clavicle Graft in Shoulder Dislocation Clavicle Auto Graft in Patient With Recurrent Anterior Shoulder Dislocation
to evaluate the clinical and radiological Outcome of Distal Clavicle Auto graft in patient with recurrent Shoulder dislocation
- Trial name
- NCT06186362
- Volunteers
- 30 people
- Sponsor
- Al-Azhar University
Anesthesia, Radical Mastectomy
Analgesic Efficacy of Ultrasound Guided Serratus Anterior Plane Block and Pectoral Nerve Block II
Modified Radical Mastectomy accounts for 31% of all breast surgeries and considered the fundamental surgical management for breast cancer. Nearly 40-60% of patients experience severe acute postoperative pain.
- Trial name
- NCT06188156
- Testing
- Anethesia
- Where
- Egypt
- Volunteers
- 99 people
- Sponsor
- Al-Azhar University
Congenital Glaucoma
Non-penetrating Deep Sclerectomy Versus Trabeculotomy- Trabeculectomy Operation in Treatment of Primary Congenital Glaucoma
The high success rate of the non-penetrating deep sclerectomy (NPDS) procedure in adult glaucomatous patients motivated some glaucoma specialists to try it as an alternative procedure in childhood PCG.
- Trial name
- NCT06189326
- Testing
- non-penetrating deep sclerectomy, primary combined trabeculotomy-trabeculectomy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Accerleration of Tooth Movement
Assessment of Maxillary Canine Retraction Using Self-ligating Brackets System Assisted With Micro-osteoperforations
Assessment of maxillary canine retraction using self-ligating brackets system assisted with micro-osteoperforations: A prospective controlled clinical study
- Trial name
- NCT05595174
- Testing
- self ligating bracket with micro osteoperforation, conventional bracket with micro osteoperforation, conventional bracket without micro osteoperforation
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Intraoperative Hemodynamics, Liposuction
Effect of Adrenaline Concentration on Intraoperative Hemodynamics of Liposuction Patients
Liposuction is a procedure that has emerged over the last 30 years as a method to remove subcutaneous fat for cosmetic purposes.
- Trial name
- NCT05822765
- Testing
- Epinephrine concentration of 1:1000000, Epinephrine concentration of 1:500000
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Irreversible Pulpitis, Endodontic Inflammation
A Clinical and Radiographic Evaluation of Low-Level Diode Laser Full Pulpotomy in Vital Permanent Teeth
In this study, patients with symptoms of irreversible pulpitis in mature permanent molars were treated with two pulpotomies techniques after random allocation in either 2 groups: Diode laser pulpotomy and traditional pulpotomy…
- Trial name
- NCT06176378
- Testing
- traditional pulpotomy, diode laser pulpotomy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Acne Vulgaris
Efficacy of Manuka Honey Nano-Formulation in the Treatment of Acne Vulgaris
The present study aims to manufacture manuka honey-loaded nano-formulation using natural materials as a potent tissue-healing remedy and compare it to commercially available antimicrobial therapy in order to reduce the severity…
- Trial name
- NCT06175819
- Testing
- Manuka honey( MgO 850, UMF+20) loaded nano-formulation
- Volunteers
- 102 people
- Sponsor
- Al-Azhar University
Threatened Miscarriage
Evaluation of Serum Levels of C Reactive Protein (CRP) and Its Correlation With Fetal Ultrasound Parameters in the Prediction of Threatened Miscarriage in the First Trimester
The goal of this observational study is to evaluate and compare in pregnant women with threatened miscarriage in the first trimester.
- Trial name
- NCT06011057
- Testing
- Serum C reactive protein (CRP) level, Ultrasound
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Postoperative Pain
Postoperative Analgesia of TAP Block for Laparoscopic Sleeve Gastrectomy
many methods were considered to control postoperative pain in laparoscopic bariatic surgery including non steroidal anti-inflammatory drugs, opioids and neuraxial block but subcostal (TAP) block has provided good analgesic effect…
- Trial name
- TAP (NCT06156657)
- Testing
- subcostal TAP block
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Al-Azhar University
Anxiety and Fear
A Comparison Between Dexmedetomidine and Propofol-fentanyl Infusions for Sedation for Colonoscopy Procedures
Background: Different intravenous sedative drugs have been utilized for colonoscopy, with many anesthetists for painless sedation or monitored anesthesia care.
- Trial name
- NCT06148103
- Testing
- Patients who received Dexmedetomodine, patients who received propofol-fentanyl
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zulekha Hospitals
Branch Retinal Vein Occlusion
Assessment Of Peri-papillary Retinal Nerve Fiber Layer Thickness In Patients With Unilateral Branch Retinal Vein Occlusion
Several studies have indicated a relation between the development of RVO and elevated intraocular pressure (IOP) and glaucoma [9].
- Trial name
- NCT06146309
- Testing
- aflibercept (2mg/0.05ml)
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Muscle Disorder
Evaluation of Digital Stabilizing Splint in Management of Masticatory Muscle Disorder
The goal of this clinical trial is to evaluate the digital stabilizing splint in management of masticatory muscle disorder. The main question it aims to answer are: is the digital stabilizing splint effective in treatment of…
- Trial name
- NCT06138535
- Testing
- digital stabilizing splint
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- zahraa hassan
Temporomandibular Joint Disorders
Evaluation of Anterior Repositioning Guided Splint Combined With or Without I Platelet-rich Fibrin
The study aims to evaluate clinically and radiographically the effectiveness of arthrocentesis and injection of I-PRF with wearing ARS in comparison to arthrocentesis and ARS only.
- Trial name
- NCT06132802
- Testing
- Patients who received treatment involving ARS and arthrocentesis only, Patients who received treatment involving ARS, arthrocentesis, and an I-PRF injection
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mahmoud Mohammed Mahmoud Nasef
Temporomandibular Joint Disorders, Orofacial Pain
Computed Guided Prolotherapy Versus Conventional Prolotherapy
The aim of that study is to compare between conventional prolotherapy and computed guided prolotherapy in treatment of temporomandibular joint (TMJ) internal derangement.
- Trial name
- NCT06132594
- Testing
- Conventional arthrocentesis followed by I-PRF injection, 3d surgical guided Arthrocentesis followed by I-PRF injection
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Lateral Sinus Lifting, Dental Implant
Volumetric Analysis of Maxillary Sinus After Guided Lateral Sinus Lift Procedure
The purpose of this study is to present a guided lateral window sinus lift (GLSL) procedure with the aid of a fully digital workflow using surgical templates for window osteotomy preparation and implant placement.
- Trial name
- NCT06130657
- Testing
- Lateral Maxillary Sinus Floor Elevation using surgical guide, Lateral Maxillary Sinus Floor Elevation without surgical guide
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Ahmed Zewail
Dental Implant, Sinus Lifting
Transcrestal Sinus Lift Using Osseodensification Versus Lateral Window Technique
The aim of this study is to evaluate the transcrestal sinus lift using Osseodensification versus lateral window technique with simultaneous implant placement.
- Trial name
- NCT06126536
- Testing
- Crestal Maxillary Sinus Floor Elevation using Osseodensification, Lateral Maxillary Sinus Floor Elevation
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Alopecia Areata
Methotrexate Versus Triamcinilone Acetonide in Treatment of Recalcitrant Alopecia Areata
Alopecia areata is the second most common cause of hair loss following androgenic alopecia. It is affecting 2% of global population with an increasing prevalence.
- Trial name
- NCT06088147
- Testing
- Methotrexate, Triamcinolone Acetonide
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Al-Azhar University
Caries of Infancy
Clinical Evaluation of Polymethyl Methacrylate CAD/CAM Crowns Versus Prefabricated Zirconia Crowns in Primary Molars
, in this studythe investigator will compare between ready-made zirconia crowns and Computer-aided design and Computer-aided manufacturing (CAD/CAM) polymethyl methacrylate (PMMA) crowns to overcome the disadvantages of…
- Trial name
- NCT06113770
- Testing
- preparation of the tooth to receive ready made zirconia crown, preparation of the tooth to receive CAD CAM PMMA custom made crown
- Where
- Egypt
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Adel Sherif Mostafa Rehab