Clinical trials: sponsored by Peking University
Femoroacetabular Impingement Syndrome
Comparison of Surgery With Prehabilitation, Direct Surgery and Rehabilitation for Patients With Femoroacetabular Impingement
This study aims to compare the therapeutic effects of three different treatment strategies for patients with femoroacetabular impingement.
- Trial name
- NCT07894471
- Testing
- Hip arthroscopic surgery, Standardized physical rehabilitation training
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Peking University Third Hospital
Non-Small Cell Lung Cancer
Gematinib Combined With Lenvatinib for the Treatment of Locally Advanced or Metastatic Non-small Cell Lung Cancer With MET Protein Overexpression: A Prospective, Multicenter, Phase II Clinical Study
Research objective: To evaluate the efficacy and safety of gematinib combined with lenvatinib in the treatment of advanced or metastatic NSCLC with MET overexpression that has failed standard therapy Experimental design…
- Trial name
- NCT07894367
- Testing
- Gematinib, Lenvatinib
- Volunteers
- 23 people
- Sponsor
- Peking University Cancer Hospital & Institute
Spinal Muscular Atrophy (SMA)
Effects of Different Stiffness Settings During Robotic Isokinetic Training in Children With SMA
This randomized, within-participant, contralateral-limb-controlled clinical trial will compare individually optimized compliant and rigid stiffness settings of a portable isokinetic knee training robot in children with spinal…
- Trial name
- NCT07822711
- Testing
- Portable Isokinetic Knee Training Robot With an Individually Optimized Compliant Setting, Portable Isokinetic Knee Training Robot With a Rigid Setting
- Where
- China
- Volunteers
- 13 people
- Sponsor
- Peking University Third Hospital
Endometrial Neoplasm Malignant Stage I
Gonadotropin-releasing Hormone Agonist (GnRHa) Plus Letrozole In Young Women With Early Endometrial Cancer
To see if Gonadotropin-releasing hormone analogue (GnRHa) combined with aromatase inhibitors (AIs) will achieve better complete response rate than megestrol acetate or medroxyprogesterone acetate (MA/MPA) alone as…
- Trial name
- NCT05247268
- Testing
- Megestrol Acetate 160 MG Oral Tablet, Medroxyprogesterone Acetate 500 MG, Triprorelin Acetate
- Where
- China
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Fudan University
Depression, Anxiety
Postoperative Anxiety and Depression Among Chinese Elderly Patients
The goal of this observational study is to learn about the prevalence of postoperative anxiety and depression symptoms and identify the related risk factors in elderly patients aged 65 and older who undergo non-cardiac surgery in…
- Trial name
- NCT07532122
- Where
- China
- Volunteers
- 7,568 people
- Sponsor
- Chinese PLA General Hospital
Chronic Pain, Postoperative
Effect of Low-Dose Esketamine Combined With Dexmedetomidine on the Incidence of Chronic Postsurgical Pain in Patients Undergoing Pancreatic Surgery
The goal of this clinical trial is to learn if low-dose esketamine combined with dexmedetomidine can reduce chronic pain after pancreatic surgery in adults. It will also learn about its safety.
- Trial name
- NCT07888413
- Testing
- Esketamine combined with dexmedetomidine
- Volunteers
- 450 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Spinal Epidural Hematoma
Establishment of Clinical Prediction Model for Postoperative Symptomatic Spinal Epidural Hematoma
The goal of this observational study is to establish a clinical prediction model based on artificial intelligence algorithms for patients with postoperative symptomatic spinal epidural hematoma(PSSEH) after spinal surgery.
- Trial name
- NCT06633848
- Testing
- spinal surgery
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Peking University Third Hospital
Gestational Diabetes Mellitus (GDM)
The WAIT Trial: Waiting Versus Active Induction at Term in Women With A1 Gestational Diabetes Mellitus
This multicenter, open-label, superiority randomized controlled trial will evaluate whether delaying planned induction from 40 weeks to 41 weeks improves delivery outcomes in women with A1 gestational diabetes mellitus (A1 GDM).
- Trial name
- NCT07831954
- Testing
- Timing of Planned Delivery
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Peking University Third Hospital
Non-Small Cell Lung Cancer (NSCLC)
MRD and Imaging Guided Adaptive Neoadjuvant Therapy for Resectable NSCLC
Neoadjuvant immunotherapy combined with platinum-based doublet chemotherapy has been established as the standard of care for driver-gene-negative (EGFR/ALK wild-type) stage II-IIIB non-small cell lung cancer (NSCLC), yielding…
- Trial name
- NCT07885709
- Testing
- PD-1 inhibitor, Carboplatin, Nab-paclitaxel
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University People's Hospital
HFpEF - Heart Failure With Preserved Ejection Fraction
Cardiopulmonary Exercise Testing-based High-intensity Interval Training For Improving Heart Failure With Preserved Ejection Fraction
Cardiovascular-Kidney-Metabolic (CKM) Syndrome is a continuous clinical disease spectrum integrating cardiovascular, renal, and metabolic disorders.
- Trial name
- CPHIT-HFpEF (NCT07693049)
- Testing
- High-intensity interval training
- Where
- 13 sites in China
- Volunteers
- 192 people
- Sponsor
- Peking University Third Hospital
Prostate Cancer
Non-inferiority Trial Omitting Drainage After Robot-assisted Radical prostatectomY
This is a multicenter, prospective, randomized, controlled, open-label, assessor-blinded, non-inferiority trial evaluating whether pelvic drainage can be safely omitted after robot-assisted radical prostatectomy (RARP).
- Trial name
- POND-RARP (NCT07887321)
- Testing
- No Pelvic Drain Placement, Pelvic Drain Placement
- Where
- 3 sites in China
- Volunteers
- 400 people
- Sponsor
- Shanghai East Hospital
Psychological Distress, Adverse Childhood Experience
EMI for Reducing Psychological Distress in Young Adults With Multiple ACEs: A RCT Study
This study is a two-arm randomized controlled trial designed to evaluate the effectiveness of an ecological momentary intervention (EMI) in reducing psychological distress among young adults with multiple adverse childhood…
- Trial name
- NCT07885579
- Testing
- EMI
- Volunteers
- 100 people
- Sponsor
- Peking University
Robotic Surgical Procedures, Airway Extubation
Site of Tracheal Extubation and Operating Room Efficiency During Robot-assisted Surgery
This study aims to evaluate the impact of different extubation strategy on the occupancy time of operating room (OR) and the incidence of adverse events and quality of recovery after robotic-assisted surgery.
- Conditions
- Robotic Surgical Procedures, Airway Extubation, Operating Rooms, Anesthesia Recovery Period
- Trial name
- NCT07332806
- Testing
- Extubation in post-anesthesia care unit (PACU), Extubation in operating room (OR)
- Where
- China
- Volunteers
- 218 people
- Sponsor
- Peking University First Hospital
Metabolic Dysfunction-Associated Steatotic Liver Disease
Impact of Live Streaming Exercise on Liver Health in MASLD Pregnant Women
Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) is a clinical and pathological syndrome characterized primarily by excessive intracellular fat accumulation in the liver, excluding alcohol-related and other…
- Trial name
- NCT06682663
- Testing
- Live Streaming Exercise
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Peking University
Autism Spectrum Disorder
FMS-CrossFit Training Program (FCTP) to Improve School Readiness in Preschool Children With Autism Spectrum Disorder
Autism spectrum disorder (ASD) is an increasing public health concern, with preschool children often exhibiting persistent deficits in school readiness.
- Trial name
- NCT07532395
- Testing
- FCTP program, treatment as usual (TAU) (Control Group)
- Where
- 2 sites in China
- Volunteers
- 184 people
- Sponsor
- Peking University
Hepatocellular Carcinoma (HCC)
SBRT Combined With Iparomlimab and Tuvonralimab (QL1706) and Bevacizumab for Hepatocellular Carcinoma
SBRT combined with dual PD-1/CTLA-4 blockade (iparomlimab and tuvonralimab, QL1706) and bevacizumab may provide complementary local and systemic antitumor activity in hepatocellular carcinoma (HCC).
- Trial name
- NCT07882056
- Testing
- Stereotactic Body Radiotherapy, Bevacizumab, Iparomlimab and Tuvonralimab
- Where
- China
- Volunteers
- 33 people
- Sponsor
- Peking University Cancer Hospital & Institute
Irritable Bowel Syndrome - Diarrhoea
Effect of Food-derived Active Components on Digestive Tract Health in Adults With Irritable Bowel Syndrome
The goal of this clinical trial is to learn if Bifidobacterium. animalis subsp. Lactis A6 Strain or resveratrol to improve the symptoms of diarrhea-predominate irritable bowel syndromes (IBS-D).
- Trial name
- NCT06779214
- Testing
- Prebiotic_L, resveratrol_L, Prebiotic_M
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Peking University
Advanced Extrapulmonary Neuroendocrine Carcinoma
A Trial of LBL-024 Combined With Platinum-based Chemotherapy for the Treatment of Advanced EP-NEC
This trial is a randomized, double-blind, placebo-controlled multicenter phase III clinical study aiming to evaluate the efficacy and safety of LBL-024 compared with placebo in combination with etoposide and cisplatin or…
- Trial name
- NCT07720193
- Testing
- LBL-024 for Injection, Etoposide injection, Cisplatin injection
- Where
- 36 sites in China
- Volunteers
- 280 people
- Sponsor
- Nanjing Leads Biolabs Co.,Ltd
Psychological Distress, Adverse Childhood Experience
EMI for Reducing Psychological Distress in Young Adults With Multiple ACEs: A Feasibility Study
This single-arm feasibility study aims to evaluate the feasibility and acceptability of an ecological momentary intervention (EMI) designed to reduce psychological distress among young adults with high levels of adverse childhood…
- Trial name
- NCT07823114
- Testing
- EMI
- Volunteers
- 20 people
- Sponsor
- Peking University
Digestive System Cancers
KN046 Plus Regorafenib or Apatinib in MSI-H Digestive System Cancers Resistant to PD-1/PD-L1 Blockade
The study is an interventional phase II clinical trial aiming to evaluate the efficacy and safety of KN046, a PD-L1 and CTLA-4 bispecific antibody, in combination with regorafenib or apatinib for microsatellite instability-high…
- Trial name
- NCT06099821
- Testing
- KN046, Regorafenib, Apatinib
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Peking University Cancer Hospital & Institute
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