Clinical trials: sponsored by Penn State University
Amyotrophic Lateral Sclerosis
Evaluating Verbal Communication in Structured Interactions: Theoretical and Clinical Implications
The goal of this clinical trial is to learn about the effect of communicative interaction on verbal communication in people with amyotrophic lateral sclerosis (ALS) and age-matched speakers.
- Trial name
- NCT06266403
- Testing
- Structured Communicative Interaction, Clear Speech, Unstructured communicative interaction
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Penn State University
Parenting, Parent-Child Relations
Promoting Co-Parenting and Reducing Hazardous Drinking in New Families
This study aims to understand if a parenting program that helps couples learn to parent as a team and maintain a healthy lifestyle, such as maintaining safer levels of alcohol use, promotes parent and child health and well-being.
- Conditions
- Parenting, Parent-Child Relations, Drinking, Alcohol, Adjustment
- Trial name
- NCT04441307
- Testing
- Healthy Foundations, Family Foundations
- Where
- 2 sites in United States
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- Penn State University
Autism Spectrum Disorder (ASD)
Promoting Physical Activity Among Young Children With Autism
Higher amounts of physical activity are linked to multiple health benefits including improved cognition, academic success, and classroom behavior for children.
- Trial name
- NCT07747129
- Testing
- Wellness Enhancing Physical Activity for Young Children (WE PLAY), Non-Physical Activity Online Training
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Northeastern University
Parkinson Disease, Multiple System Atrophy, Parkinson Variant
Automated Imaging Differentiation of Parkinsonism
The purpose of this study is to test the performance of the AID-P across 21 sites in the Parkinson Study Group. Each site will perform imaging, clinical scales, diagnosis, and will upload the data to the web-based software tool.
- Conditions
- Parkinson Disease, Multiple System Atrophy, Parkinson Variant, Progressive Supranuclear Palsy
- Trial name
- AIDP (NCT05913687)
- Testing
- AIDP
- Where
- 21 sites in United States, Canada
- Volunteers
- 315 people
- Sponsor
- University of Florida
Aging
E-training of Inmate Peer Caregivers for Enhancing Geriatric and End-of-life Care in Prisons
The demographics of the U.S. prison population are shifting at a dramatic rate requiring new approaches to prison healthcare. Current estimates suggest that there are 2.3 million incarcerated persons in the U.S.
- Trial name
- NCT05017129
- Testing
- Just Care
- Where
- 2 sites in United States
- Volunteers
- 83 people
- Sponsor
- Klein Buendel, Inc.
Endometriosis
Thromboxane Function in Women With Endometriosis
The goal of this clinical trial is to compare neurovascular regulation in women with endometriosis and healthy women. The main questions it aims to answer are: Do women with endometriosis have greater blood pressure and pain…
- Trial name
- NCT05962034
- Testing
- Aspirin
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Penn State University
Endometriosis
Endometriosis and Microvascular Dysfunction: Role of Inflammation
The purpose of this study is to better understand the underlying mechanisms associated with elevated cardiovascular disease risk in women with endometriosis, and to measure the effectiveness of emerging endometriosis treatments…
- Trial name
- Endo3/SA2 (NCT05069740)
- Testing
- Salsalate Pill
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Penn State University
Endometriosis
Endometriosis and Microvascular Dysfunction; Simvastatin and Duavee
Purpose: To determine the effects of SERM and simvastatin interventions on endothelial dysfunction in women with endometriosis. Hypothesis: Treatment with the SERM (bazedoxifene + conjugated estrogen) or with simvastatin will…
- Trial name
- Endo2/SA3 (NCT05059626)
- Testing
- simvastatin 10mg, Bazedoxifene 20/Estrogens,Con 0.45Mg Tb
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Penn State University
Aging
Transient Receptor Potential Channels
Neurovascular signaling in the skin associated with stimulation of the transient receptor potential (TRP) channels. These channels are stimulated by both temperature and naturally occurring bioactive agents found in mint, chili…
- Trial name
- TRP (NCT06444594)
- Testing
- TRPM8 Agonist, TRPV1 Agonist, TRPV4 Agonist
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Penn State University
Underage Drinking, Cannabis Use
Project e-PBI+ - Parent Intervention to Reduce College Student Drinking and Cannabis Use
College students' risky drinking and cannabis use are major public health problems. The harms associated with risky drinking have been well-documented (such as deaths, blackouts, injuries, assaults, arrests, sexual consequences…
- Conditions
- Underage Drinking, Cannabis Use, Drinking, Teen, Drinking, College
- Trial name
- NCT05345951
- Testing
- e-PBI+, e-PBI
- Where
- United States
- Volunteers
- 1,980 people, healthy volunteers welcome
- Sponsor
- Penn State University
Dementia Caregiver
Developing and Testing a Brief Mindfulness Just-in-time Adaptive Intervention for Reducing Stress of Dementia Caregivers
1. To determine an effective decision rule for delivering brief mindfulness prompts as a function of caregivers' real-time stress state, including whether prompt delivery affects subsequent stress and affect and whether this…
- Trial name
- NCT07714681
- Testing
- Group 1 - Vulnerability, Group 2 - Receptivity
- Where
- Hong Kong
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Education University of Hong Kong
Prediabetes
Cardiometabolic & Cognitive Effects of Peanut Butter in Prediabetes
The purpose of this study is to look at the effect of consuming peanut butter at breakfast on blood sugar control, cognitive function, and heart disease risk factors in middle-aged adults with prediabetes.
- Trial name
- NCT07714096
- Testing
- Peanut butter, Usual diet
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Penn State University
Healthy
Using an AI Mobile Application to Promote Healthy Eating
The goal of this feasibility study is to determine the adherence, acceptability, and usability of the behavioral intervention of a mobile AI application and its effects on food choices and diet quality.
- Trial name
- NCT07108452
- Testing
- A mobile application that uses AI to deliver behavioral nudges that encourage healthy food choices., Limited app version for dietary assessment only
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Antimicrobial Resistance
Optimizing Antibiotics Prescription
Interventions that are low-cost, do not add substantially to the physician workload, are consistent with good physician practices and WHO guidelines, and serve as a reminder on the risks of overprescribing antibiotics are…
- Trial name
- NCT06436690
- Testing
- Diagnosis Mandate, Individualized Feedback
- Where
- 2 sites in United States, Nepal
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Penn State University
Upper Resp Tract Infection
Community Interventions for Tackling Antimicrobial Resistance in Ghana
This research project aims to test the effect of two interventions targeted to community pharmacies in the Greater Accra region, Ghana, on antibiotics dispensing rates.
- Trial name
- CITAR-Ghana (NCT07284914)
- Testing
- Individualized Feedback, Legal Reminder
- Where
- Ghana
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Penn State University
Fermented Food, Inflammation
Comparing Effects of Fermented and Unfermented Pulses and Gut Microbiota
The goal of this clinical trial is to learn about the effects of consuming fermented pulses (certain types of legumes like chickpeas or lentils) in healthy people. The main questions it aims to answer are: 1.
- Trial name
- NCT06134076
- Testing
- Unfermented chickpea, Fermented chickpea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Penn State University
Anhedonia, Depression
Prevention of Anhedonia in Children
This trial will test the effects of a positive emotion-focused preventive intervention on reward responsiveness in children of mothers with histories of depression and anhedonia.
- Trial name
- NCT05988138
- Testing
- Family Promoting Positive Emotions, Psychoeducation
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Vanderbilt University
Autism Spectrum Disorder
Trial of Autism Parent Navigator Program
To address the dual needs of parents for support in navigating Autistic Spectrum Disorder (ASD) services and maintaining positive family functioning, the investigators propose to test Autism Parent Navigators (APN), an innovative…
- Trial name
- APN (NCT04744428)
- Testing
- Autism Parent Navigators, Peer mentoring
- Where
- United States
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- Penn State University
High Risk Drinking, College Student Drinking
Biomarker Feedback Intervention
The goal of the study is to examine alcohol use behaviors of young adults through the use of testing the feasibility of adding an innovative brief personalized alcohol biomarker feedback component (TAC feedback) to an existing…
- Trial name
- NCT07307326
- Testing
- eCHECKUP TO GO (eCTG), eCHECKUPTOGO + brief personalized alcohol biomarker feedback intervention (eCTG + TAC)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Penn State University
Bone and Bones, Body Composition
DXA Study of Precision and Reliability
The purpose of the study is to assess precision of the GE Lunar iDXA, Hologic Horizon W DXA scanner, and the Stratec peripheral quantitative computed tomography (pQCT) scanner.
- Trial name
- NCT03621306
- Testing
- DXA and pQCT precision testing
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Penn State University