Clinical trials: sponsored by University of Nebraska
Colorectal Cancer, Prevention
A Cross-sectional Partnership to Improve Prevention and Health Equity Among African Americans
African Americans face racial disparities in colorectal cancer (CRC), with lower screening rates and higher incidence and mortality rates.
- Trial name
- NCT05903885
- Testing
- On-site Fecal Immunochemical Test (FIT) Kit Distribution, On-site With Social Media Advertising Fecal Immunochemical Test (FIT) Kit Distribution
- Where
- 2 sites in United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Long COVID
Heat thErapy And mobiLity in COVID-19 Survivors
Post-acute sequelae of SARS-CoV-2 infection (PASC) is becoming a major risk factor for chronic diseases, with older adults and those with underlying health conditions at risk of developing persistent mobility limitations and…
- Trial name
- HEAL (NCT06928116)
- Testing
- Heat therapy, Walking
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- University of Nebraska
Non-small Cell Lung Cancer
Trabedersen (OT-101) With Pembrolizumab for Newly Diagnosed Advanced NSCLC and Positive PD-L1
The goal of this clinical trial is to: 1) evaluate the safety and recommended dose of the drug OT-101/Trabedersen when combined with Pembrolizumab and 2) determine the efficacy of the combination therapy in adults with certain…
- Trial name
- NCT06579196
- Testing
- Trabedersen, Pembrolizumab
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Nebraska
Profound Autism
Empowering Caregivers to Promote Child Independence
The proposed study aims to address the unique needs of caregivers and their adolescent children with profound autism. The constant supervision and 24/7 care that caregivers need to provide their children to ensure their health…
- Trial name
- NCT07059364
- Testing
- CAST Treatment
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Nebraska
Low Vision, Low Vision Aids
Beacon Sensors and Telerehabilitation to Assess and Improve Use of Devices (BeST-AID) for Low Vision
One goal of this research is to conduct a non-inferiority trial of telerehabilitation versus in-office care to provide follow-up training to individuals with low vision to enhance their quality of life by using magnification…
- Trial name
- BeST-AID (NCT06107881)
- Testing
- Low Vision Rehabilitation
- Where
- 9 sites in United States
- Volunteers
- 350 people
- Sponsor
- University of California, Los Angeles
Dietary Intervention, Gut Microbiota
Phenolic Dependent And Independent Effects Of Whole Grain Sorghum On Immunometabolism
Sorghum is a nutrient-dense ancient grain that, when eaten as a whole grain, provides health-beneficial dietary fiber, protein, and phenolics.
- Conditions
- Dietary Intervention, Gut Microbiota, Insulin Sensitivity/Resistance, Obesity & Overweight
- Trial name
- NCT07832071
- Testing
- Whole grain sumac sorghum, Whole grain white sorghum, White rice
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Prostate Cancer
PSMA-PET Guided De-escalation of Salvage Radiation Treatment in Recurrent Prostate Cancer
Purpose: Prospective, single-site Phase II study testing whether PSMA-PET/MRI-guided, de-escalated salvage radiation reduces acute Grade ≥2 toxicity versus a 44% historical rate, while maintaining cancer control after…
- Trial name
- NCT07234981
- Testing
- PSMA-guided Salvage Radiation
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Nebraska
PTSD
Safety and Efficacy of Cannabidiol (CBD) for Symptoms of PTSD in Adults
Post-traumatic stress disorder (PTSD) is a psychiatric disorder than may develop following a traumatic event including serious incidents, natural or human-caused disasters, violence, death of a loved one, receipt of traumatic…
- Trial name
- NCT05269459
- Testing
- Cannabidiol Administered as Nantheia ATL5
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- University of Nebraska
Peripheral Artery Disease (PAD)
Detecting Peripheral Artery Disease With the Pulse
1) The purpose of this study is to assess segmental pulse arrival time (PAT) as an alternative biomarker to detect lower-extremity peripheral artery disease (PAD), and to investigate the impacts of local skin heating and foot…
- Trial name
- NCT07226193
- Testing
- Segmental pulse arrival time assessment
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Healthy Volunteer, Older Adults (65-85 Years)
Safety and Tolerability Trial of Psilocybin in Healthy Older Adults
This study plans to learn more about the safety and tolerability of psychedelic administration (psilocybin) in healthy older adults ages 65-85.
- Trial name
- Psil-Pk (NCT07516405)
- Testing
- Psilocybin (Usona Institute)
- Where
- 6 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Recurrent High Grade Glioma, Anaplastic Astrocytoma
A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent Glioma
Glioblastoma (GBM), WHO grade IV glioma, represents the majority of adult malignant primary brain tumors, with an incidence of 2-3 per 100,000 person-years.
- Conditions
- Recurrent High Grade Glioma, Anaplastic Astrocytoma, Anaplastic Oligodendroglioma, Glioblastoma
- Trial name
- NCT05698524
- Testing
- PCI 24781, Temozolomide
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Nebraska
Wound Healing
Post-Extraction Wound Healing in Elderly
Patients presenting to the University of Nebraska Medical Center College of Dentistry for a posterior extraction will be offered participation in the study.
- Trial name
- NCT07796269
- Testing
- tooth extraction
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Nebraska
Healthy Children, CP (Cerebral Palsy)
Training Upper Limbs of Neurodiverse Children by Connecting Brain Activities to a Virtual Reality Based Game
This study is testing ways to help children with cerebral palsy (CP) improve how their hands work. Investigators want to see if brain activity using a virtual reality (VR) program can make their hands work better.
- Conditions
- Healthy Children, CP (Cerebral Palsy), CP, Cerebral Palsy
- Trial name
- NCT06818877
- Testing
- Brain-Computer Interface (BCI)-HABIT-VR, Hand and Bimanual Intensive Therapy Virtual Reality (HABIT-VR)
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Osteogenesis Imperfecta
BBD Longitudinal Study of Osteogenesis Imperfecta
Osteogenesis Imperfecta (OI) is a rare disorder of increased bone fragility characterized by fractures with minimal or absent trauma, dentinogenesis imperfecta (DI), and, in adult years, hearing loss.
- Trial name
- NCT02432625
- Where
- 12 sites in United States, Canada
- Volunteers
- 1,000 people
- Sponsor
- Baylor College of Medicine
Brain Injuries
Metacognition in Neurological Injury
The purpose of this study is to investigate the trajectory of metacognitive functioning throughout phases of recovery from neurological insult, and to determine its relationship to rehabilitation compliance and functional…
- Trial name
- NCT03752697
- Testing
- metacognitive performance
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Alcohol Drinking, Violence in Adolescence
The Healthy Families Bright Futures Program
The goal of this clinical trial is to learn about an online group program (Healthy Families Bright Futures program) for LGBTQ+ teens and their caregivers.
- Trial name
- NCT06309134
- Testing
- Healthy Families Bright Futures Program
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Colorado Springs
Childhood Obesity Pevention, Diet Quality
Healthy Children, Healthy Communities: Effectiveness of a Multilevel Rural Community Engagement Model for Improving Children's Dietary Intake in Family Child Care Homes
The purpose of this study is to find out whether a program called "Healthy Children, Healthy Communities" can help young children in rural areas eat healthier and improve their health.
- Conditions
- Childhood Obesity Pevention, Diet Quality, Feeding Behaviors, Health Behavior Change
- Trial name
- NCT07160530
- Testing
- EAT Family Style, Better Kid Care
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Implementation Science, Engagement, Patient
Parents Helping Parents for Youth Vaping Cessation
The goal of this randomized controlled study is to test if this new intervention works to help adolescents quit vaping. A key feature of the program is the use of peer support for parents, delivered by trained parent coaches.
- Conditions
- Implementation Science, Engagement, Patient, E Cigarette Use, Peer Support
- Trial name
- PhP-VX (NCT07207850)
- Testing
- Parents Helping Parents program
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Nebraska
Allogeneic Hematopoietic Stem Cell Transplant (Allo-HSCT)
Enteral Nutrition Versus Standard of Care in Allogeneic Hematopoietic Stem Cell Transplantation
This is a randomized controlled phase II trial which will enroll 112 patients with a diagnosis of a blood cancer or a serious blood disorder who plan to undergo an allogenic hematopoietic stem cell transplant using any…
- Trial name
- NCT07315165
- Testing
- Enteral Nutrition
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- University of Nebraska
Well-Being, Psychological, Engagement
The Impact of the Family Room App on Caregivers
Engaging families in patient care during serious illness can enhance care quality, reduce social isolation, boost satisfaction, and lower healthcare costs.
- Conditions
- Well-Being, Psychological, Engagement, Satisfaction, Consumer
- Trial name
- NCT06463158
- Testing
- Family Room Application
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Nebraska