Find a clinical trial
Acute Lymphobkastic Leukemia
Establishment of a Novel Flow Cytometric Diagnostic Assay to Effectively Evaluate Immune Reconstitution After Hematopoietic Stem Cell Transplantation for Acute Lymphoblastic Leukemia
Primary Objective To assess immune reconstitution during the first 18 months following hematopoietic stem cell transplantation (HSCT) for acute lymphoblastic leukemia (ALL), with a particular focus on the T-cell compartment…
- Trial name
- Flow HSCT IR f (NCT07899840)
- Where
- 3 sites in Austria, Italy
- Volunteers
- 150 people
- Sponsor
- Fondazione Matilde Tettamanti Menotti De Marchi Onlus
Smoking
Using Smartwatches to Monitor Smoking in Real-life Situations
Background: It is important to quickly identify when people are at risk of smoking. Most current methods rely on people reporting when they smoke or what makes them want to smoke.
- Trial name
- NCT07067151
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute on Minority Health and Health Disparities (NIMHD)
Cataract, Vitreous Hemorrhage
Surgical Procedure Efficiency Evaluation stuDy
The purpose of this real-world evidence study is to compare surgical procedure times for UNITY® VCS and CONSTELLATION® Vision System.
- Conditions
- Cataract, Vitreous Hemorrhage, Retinal Detachment, Macular Pucker
- Trial name
- NCT07228091
- Testing
- UNITY VCS, CONSTELLATION
- Where
- United Kingdom
- Volunteers
- 180 people
- Sponsor
- Alcon Research
Severe Pneumonia
Detection and Characterization of Lower Respiratory Infections in Critically Ill Patients
This study is a prospective observation study for lower respiratory tract infections in medical intensive care unit. Microbiologic and clinical characteristics and outcomes of patients with severe pneumonia in medical intensive…
- Trial name
- NCT01068990
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Asan Medical Center
Breast Cancer
Opportunistic Breast Cancer Screening Using Non-Contrast Chest CT
The goal of this observational study is to evaluate the feasibility and effectiveness of using non-contrast chest computed tomography scans for opportunistic breast cancer screening, and to further compare its diagnostic…
- Trial name
- OPBCS-CT (NCT07557654)
- Where
- China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Fudan University
Benign Prostatic Hyperplasia (BPH)
To Linguistically and Psychometrically Validate the Hong Kong Chinese Version of the BPH 3-item Questionnaire
This study is to linguistically and psychometrically validate the translated and culturally adapted Hong Kong Chinese version of the BPH 3-item questionnaire.
- Trial name
- NCT05785286
- Testing
- BPH 3-item questionnaire
- Where
- 2 sites in Hong Kong
- Volunteers
- 66 people
- Sponsor
- Chinese University of Hong Kong
Overweight or Obesity
Healthy Living BEYOND Weight Study
The Healthy Living BEYOND Weight Study is an observational research study of participants living with overweight and obesity. The principal objectives for this project will be to answer fundamental unanswered questions regarding…
- Trial name
- NCT07075341
- Testing
- None - Observational study
- Where
- United States
- Volunteers
- 1,000,000 people
- Sponsor
- American Heart Association
Healthy Volunteer
Visual Attention, Object Recognition, and Eye Movements in Healthy Volunteers
Background: Vision is vital for many of our daily activities. Researchers want to learn more about how we aim our eyes (that is, what images, such as faces, immediately attract our attention) and how we direct our attention (that…
- Trial name
- NCT07756853
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Eye Institute (NEI)
Motor Development
Motor Development of Normal Children
The goal of this type of study: observational study is to compare motor development between urban and rural regions in pre-school age children.
- Trial name
- NCT05948176
- Testing
- The Bruininks-Oseretsky Test of Motor Proficiency, Second Edition
- Where
- 2 sites in Egypt
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Cairo University
Endometriosis, Endometriosis Rectum
Clinical Impact of Ultrasound Diagnosis in Bowel Endometriosis
This retrospective single-centre study evaluates how accurately preoperative ultrasound detects bowel involvement in women with deep endometriosis, using surgical findings as the reference.
- Conditions
- Endometriosis, Endometriosis Rectum, Endometriosis Pelvic, Endometriosis Colon
- Trial name
- NCT07900698
- Testing
- preoperative transvaginal ultrasound
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Erasme University Hospital
Staphylococcal Infections
Modeling Host-Pathogen Interaction Using Lymphoid Organoids
Background: Staphylococcus aureus (S.aureus) are bacteria that can make people sick. Sometimes, an S. aureus infection can develop inside the spine; these infections can lead to paralysis and death. Researchers do not know how S.
- Trial name
- NCT06479837
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Healthy Volunteers
Survey to Determine Incarcerated Persons' Views on Surrogate Decision Making
Background: About 180,000 of the people in US prisons are over 55 years old. Aging people often cannot make medical decisions on their own.
- Trial name
- NCT07751731
- Testing
- Survey
- Where
- United States
- Volunteers
- 75,000 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Hypercholesterolemia, Cardiovascular Risk
Long-Term Cardiovascular Impact of ArmoLIPID Cholesterol Plus: An In Silico Study Using Digital Twins
The goal of this study, conducted entirely using computer simulations, is to evaluate the projected long-term cardiovascular impact of the new ArmoLIPID Cholesterol Plus formulation in adults with mild-to-moderate…
- Trial name
- ARMOLIPID-DT (NCT07892092)
- Where
- Spain
- Volunteers
- 100,000 people
- Sponsor
- Aeterna Medical Solutions SL
Acute Kidney Injury, Fluid Overload
Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates 2.0
There is a growing focus on short- and long-term kidney health in neonates, including those with acute kidney injury (AKI). AKI occurs commonly in the Neonatal Intensive Care Unit (NICU) and is associated with adverse outcomes.
- Conditions
- Acute Kidney Injury, Fluid Overload, Prematurity Complications, Risk Factors
- Trial name
- AWAKEN 2 (NCT06823115)
- Where
- 125 sites in United States, Argentina and 31 more
- Volunteers
- 8,000 people
- Sponsor
- Indiana University
Chronic Anal Fissure
Low Versus High Dose OnabotulinumtoxinA for Chronic Anal Fissure
This prospective single-center cohort study describes short-term and one-year clinical outcomes of two routine doses of OnabotulinumtoxinA (20 units versus 50 units) for chronic anal fissure refractory to conservative therapy.
- Trial name
- NCT07543315
- Testing
- OnabotulinumtoxinA
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Tanta University
Streptococcal Pharyngitis, Group A Streptococcal Infection
A Multicenter Evaluation of SalivIQ™ Strep A for Detecting Group A Streptococcus From Saliva and Throat Swabs in Patients With Acute Pharyngitis
The goal of this observational study is to learn how well the SalivIQ™ Strep A test detects Group A Streptococcus, the bacteria that cause strep throat.
- Trial name
- NCT07891728
- Testing
- qPCR
- Where
- 3 sites in United States
- Volunteers
- 668 people
- Sponsor
- SalivIQ Diagnostics, Inc.
Stomach Neoplasms, Gastric Cancer (Diagnosis)
Lymph Node Metastasis Pattern After Neoadjuvant Chemoimmunotherapy in LAGC
The purpose of this observational study is to learn how stomach cancer that has spread to nearby lymph nodes responds to standard chemotherapy combined with immunotherapy given before surgery.
- Conditions
- Stomach Neoplasms, Gastric Cancer (Diagnosis), Gastric Adenocarcinoma
- Trial name
- NCT07899775
- Testing
- Neoadjuvant SOX chemotherapy combined with PD-1 inhibitor
- Volunteers
- 103 people
- Sponsor
- Hainan General Hospital
Cardiometabolic Risk Factors, Mental Health
A Natural History of Cardiometabolic Disease Among US Bhutanese: Developing the Cross-Sectional Bhutanese Community of Central Ohio Health Study to Understand Acculturation as Synergizing Socioenvironmental and Biobehavioral Risk Factors Propagating ...
Background: As of 2021, almost 45 million people in the United States were foreign-born immigrants. South Asians, including people from Bhutan, are the fastest-growing immigrant subgroup in the US.
- Trial name
- NCT06991751
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Psoriasis Palmaris, Psoriasis Genital
Efficacy of Tildrakizumab in Difficult-to-treat Areas in Psoriasis
Psoriasis is a chronic inflammatory disease that affects between 2% and 4% of the French population.Some specific localizations are more difficult to manage, such as the scalp, nails, genital region and palmoplantar…
- Conditions
- Psoriasis Palmaris, Psoriasis Genital, Psoriasis of Scalp, Psoriasis Plantaris
- Trial name
- ZODIPSO (NCT05938361)
- Testing
- Psoriasis clinical assessments, Quality of life evaluation, Satisfaction assessment
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Clin4all
Prostatectomy, Cystectomy
Hugo™ RAS Urology Post-Market Clinical Study
The purpose of this study is to collect evidence on the safety and performance of the Medtronic Hugo™ RAS System when used for urologic RAS procedures.
- Conditions
- Prostatectomy, Cystectomy, Nephrectomy, Urologic Cancer
- Trial name
- NCT07901049
- Testing
- Robotic Assisted Urologic Surgery
- Volunteers
- 110 people
- Sponsor
- Medtronic - MITG