Clinical trials: sponsored by Al-Azhar University
Periodontitis
Growth Factors Release of PRF and PRGF
Background: platelet concentrate could enhance growth factors (GF) crevicular fluid levels which might be crucial to proper tissue repair and wound healing.
- Trial name
- NCT02447510
- Testing
- group 1 bio-oss bone xenograft, group 2 platelet rich in growth factor (autogenous platelet rich in growth factor), group 3 platelet rich fibrin (autogenous platelet rich fibrin)
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Vascular Endothelial Growth Factor Overexpression, Membrane Alteration
Perforated Barrier Membranes Maintain Physiologic Gingival Crevicular Fluid Growth Factor Levels
Membrane modifecation: Guided tissue membrane perforations may serve as a more biologic scaffold that could allow for the free passage of biologic mediators from the periosteum and overlying gingival connective tissue into the…
- Trial name
- NCT02168322
- Testing
- collagen membrane
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Pocket Depth, Plaque Accumulation
Microbial and Periodontal Changes Associated With Conventional Versus Self Ligating Brackets
Microbial and periodontal changes associated with conventional versus self ligating brackets. The aim of this study will be to compare microbial and periodontal changes associated with conventional versus self ligating brackets.
- Conditions
- Pocket Depth, Plaque Accumulation, Gigival Bleeding
- Trial name
- NCT02436525
- Testing
- conventional stainless steel orthodontic brackets ligated with stainless steel ligature (Oromco - USA), passive self-ligating stainless steel orthodontic brackets (Oromco - USA), active self-ligating stainless steel orthodontic brackets (Oromco - USA)
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Premature Ovarian Failure
"It is a Real" The First Baby Of Autologous Stem Cell Therapy in Premature Ovarian Failure
The purpose of this work is to evaluate the therapeutic potential of Autologous Mesenchymal sc (MSC) therapy in women suffering from POF.
- Trial name
- NCT02372474
- Testing
- Stem cell
- Where
- Egypt
- Volunteers
- 112 people
- Sponsor
- Al-Azhar University
Periodontal Pocket
Marginal Periosteal Pedicle Flap - Platelet Rich Fibrin Barriers in Treating Periodontal Intrabony Defects
The use of autogenous graft materials has been recorded to be a gold standard in regenerative therapy. This study directed toward evaluation of two autogenous regenerative materials, marginal periosteal pedicle graft (MPP) and…
- Trial name
- NCT02359539
- Testing
- Regenerative therapy
- Volunteers
- 10 people
- Sponsor
- Al-Azhar University
Infertility
Edessy ICSI Outcome Embryo Score (EIOS) Efficacy
Purpose of this study is to detect outcome of intracytoplasmic sperm injection (ICSI) according to EIOS
- Trial name
- NCT02082288
- Testing
- Edessy ICSI Outcome Embryo Score
- Where
- Egypt
- Volunteers
- 243 people
- Sponsor
- Al-Azhar University
Pregnancy, Childbirth and Puerperal Disorders
Effects of Pregnancy and Childbirth on Pelvic Floor Morphology and Sexual Function in Egyptian Women
The purpose of this study is t o evaluate levator ani morphology following normal vaginal delivery and cesarean section (elective and emergent), using three-dimensional (3D) ultrasound, and to study the effect of mode of delivery…
- Trial name
- NCT02338219
- Testing
- postpartum female pelvic floor muscle affection, postpartum sexual function in Egyptian women.
- Volunteers
- 120 people
- Sponsor
- Al-Azhar University
Hepatic Encephalopathy
The Effects of Nitazoxanide in Hepatic Encephalopathy
Evaluating the efficacy and safety of nitazoxanide in comparison to standard treatment in patients with grade II-III hepatic encephalopathy (HE).
- Trial name
- NCT02334163
- Testing
- Nitazoxanide, Oral lactulose, Metronidazole
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Ain Shams University
Infertility
Early Embryo Cleavage And Multiple Pregnancies After ICSI
To observe whether Number of early cleavage embryos can be a predictor for multiple pregnancies after ICSI.
- Trial name
- NCT02265055
- Testing
- transfer early cleavage embryos, transfer non early cleavage embryo
- Volunteers
- 193 people
- Sponsor
- Al-Azhar University
Pregnancy, Childbirth and Puerperal Disorders
Effects of Pregnancy and Childbirth on Pelvic Floor Morphology and Sexual Function in Egyptian Women
To evaluate levator ani muscle morphology following normal vaginal delivery and cesarean section (elective and emergent), using three-dimensional (3D) transperineal ultrasound, and to study the effect of mode of delivery on…
- Trial name
- NCT02245386
- Testing
- transperineal pelvic floor ultrasound
- Volunteers
- 120 people
- Sponsor
- Al-Azhar University
Fecal Incontinence
Stem Cells Therapy for Fecal Incontinence in Children After Posterior Sagittal Ano-rectoplasty
The problem of the incontinence imposes considerable strain on the child and their parents. These patients suffer from a long-life handicap and they need support and follow-up.
- Trial name
- NCT02161003
- Testing
- Stem Cells Injection Technique, Stem Cell Isolation
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Al-Azhar University
Problems With Access to Health Care
Quality Assurance of Obstetrics and Gynecology Department
This work aimed to prepare the obstetrics and gynecology department for high education and health care accreditation.
- Trial name
- NCT02101502
- Testing
- Questioner
- Where
- Egypt
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Premature Ovarian Failure
Pregnancy After Stem Cell Transplantation in Premature Ovarian Failure
Out of 112 high risk patients for Premature Ovarian Failure (POF), diagnosis was established in 10 cases. ESS cut off point for menstruation and pregnancy was 6.
- Trial name
- POF (NCT02151890)
- Testing
- Stem Cell
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Al-Azhar University
Premature Ovarian Failure
Autologous Mesenchymal Stem Cells Transplantation In Women With Premature Ovarian Failure
Stem cells (SC) are the foundation cells for every organ, tissue and cell in the body. They are undifferentiated "blank" cells that do not yet have a specific function.
- Trial name
- NCT02062931
- Testing
- Stem Cell Preparation and Injection
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sayed Bakry
Endometriosis, Ovarian
Edessy Stem Cell Score (ESS), Endometrium, Endometrioma
Purpose of this study is to evaluate stem cell expression (SCE) in endometriotic (E) and non endometriotic ovarian and endometrial tissues.
- Trial name
- NCT02103452
- Testing
- Ovarian and endometrial samples
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Al-Azhar University
Urinary Incontinence
Transurethral Myoblast Injection for Urinary Incontinence in Children With Bladder Exstrophy
Muscle precursor cells constantly regenerate striated muscles, and include the quiescent satellite cells located beneath the basal lamina of skeletal myofibers, which are responsible for repair of the terminally differentiated…
- Trial name
- NCT02075216
- Testing
- Myoblast Transplantation, Neonatal Cystourethroscope Injection
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Al-Azhar University
Age Related Macular Degeneration
Safety Study of Use of Autologous Bone Marrow Derived Stem Cell in Treatment of Age Related Macular Degeneration
The purpose of this Phase I/II study is to investigate the safety and preliminary efficacy of unilateral intravitreally transplantation of adult bone marrow stem cells in subjects with geographic atrophy secondary to age-related…
- Trial name
- NCT02016508
- Testing
- autologous bone marrow derived stem cells
- Where
- Egypt
- Volunteers
- 1 people
- Sponsor
- Al-Azhar University
Postpartum Hemorrhage
Oxytocin, Carbetocin and Misopristol for Treatment of Postpartum Hemorrhage: A Multicentric Randomized Trial
Postpartum hemorrhage (PPH) is the leading cause of maternal death worldwide, with an estimated mortality of 140 000 per year. Uterine atony is one of the most important causes of PPH.
- Trial name
- NCT01600612
- Testing
- carbetocin, misopristol, oxytocin
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Sohag University
Periodontal Pocket
Gingival Crevicular Fluid Bone Morphogenetic Protein - 2 Release Profile Following the Use of Perforated Membrane
One of the most important elements suggested to be provided through membrane perforations to augment regeneration are cell released growth factors from the overlying periosteal and gingival cells.
- Trial name
- MPM (NCT01860495)
- Testing
- perforated membrane, G2
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Chronic Spinal Cord Injury
Cell Transplant in Spinal Cord Injury Patients
This study is designed to assess the safety of autologous bone marrow derived cell transplant in chronic spinal cord injury patients.
- Trial name
- NCT00816803
- Testing
- Autologous bone marrow transplant, Physical therapy
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University