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Larynx Neoplasm, Laryngectomy; Status
Validation and Cross-cultural Adaptation of Croatian SECEL Questionnaire
Self-Evaluation of Communication Experiences after Laryngectomy (SECEL) questionnaire has been developed, with the aim of evaluating rehabilitation needs and the psychosocial care for patients with laryngeal cancer.
- Conditions
- Larynx Neoplasm, Laryngectomy; Status, Communication, Quality of Life
- Trial name
- NCT05346237
- Testing
- Quality of life questionnaire
- Where
- Croatia
- Volunteers
- 50 people
- Sponsor
- Osijek University Hospital
Coronary Artery Disease
Validation of a Vital Signs Monitoring Wristband
Today, continuous monitoring of vital signs remains a challenge since it generally requires the patient to be connected to multiple wired sensors, which restricts patient mobility in the intra-mural setting and complicates home…
- Trial name
- MULTI-VITAL (NCT05566886)
- Testing
- Continuous measurement of photoplethysmography at the wrist
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Corsano Health B.V.
Mental Health Disorder, Eating Disorders
MUMMIBODIES. Eating Disorders, Pregnancy and Post Partum Period.
MUMMIEBODIES is a research study when women with eating disorders encounter pregnancy, childbirth and postpartum. These are some condensed months that represent major challenges for this group.
- Conditions
- Mental Health Disorder, Eating Disorders, Pregnancy Related, Post Partum
- Trial name
- NCT04550364
- Where
- Norway
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bente Sommerfeldt
Diabetes, Diabetes Distress
Tailored Approaches to Reduce Distress and Improve Self-Management for Veterans With Diabetes
Veterans with diabetes may become overwhelmed with the self-management behaviors needed to maintain optimal health. Veterans may experience diabetes distress (DD), a concept distinct from depression, due the amount and frequency…
- Conditions
- Diabetes, Diabetes Distress, Self-Management, Veteran
- Trial name
- TARDIS (NCT04587336)
- Testing
- Cognitive Interview, Baseline Survey, Qualitative Interviews
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- VA Office of Research and Development
Patellar Tendinopathy
Evaluation of the Effectiveness of Extracorporeal Shockwave Therapy in Patients With Patellar Tendinopathy on Its Micromorphology
This work is designed as a prospective cohort study, in which the effects of low-energy focused extracorporeal shock wave therapy (ESWT) in patients with Patellar tendinopathy (PT) will be monitored on its micromorphology.
- Trial name
- NCT06102421
- Testing
- BTL-6000 FSWT
- Where
- Czechia
- Volunteers
- 42 people
- Sponsor
- University Hospital, Motol
Geographic Atrophy
Patients With Geographic Atrophy and Their Patient Journey in the United States (US)
To quantify and describe patients with a Geographic Atrophy (GA) diagnosis in at least one eye, and the progression to neovascular Age-Related Macular Degeneration (including how many receive Anti-VEGF), or to GA (in the fellow…
- Trial name
- NCT05891275
- Where
- United States
- Volunteers
- 68,563 people
- Sponsor
- Boehringer Ingelheim
Type 2 Diabetes
Nutrition-Focused Approach During CGM Initiation: A Qualitative Study
The purpose of the qualitative research is to provide a deeper understanding of the perspectives of people with type 2 diabetes (T2D) who received a nutrition-focused approach (NFA) when initiating continuous glucose monitor…
- Trial name
- NCT05988957
- Testing
- Semi-structured interviews using an IRB-approved interview guide
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- HealthPartners Institute
PE - Pulmonary Embolism, PE - Pulmonary Thromboembolism
FlowTriever for Acute Massive Pulmonary Embolism (FLAME)
To evaluate treatment outcomes of patients diagnosed with high-risk (massive) pulmonary embolism
- Trial name
- FLAME (NCT04795167)
- Where
- 11 sites in United States
- Volunteers
- 115 people
- Sponsor
- Inari Medical
Oral Cavity Squamous Cell Carcinoma
Helical CT, PET/CT, MRI, and CBCT Alone or in Combination in Predicting Jaw Invasion in Patients With Oral Cancer
This clinical trial studies how well helical computed tomography (CT), positron emission tomography (PET)/CT, magnetic resonance imaging (MRI), and cone beam computed tomography (CBCT) work alone or in combination in predicting…
- Trial name
- NCT03053960
- Testing
- Computed Tomography, Positron Emission Tomography and Computed Tomography Scan, Cone-Beam Computed Tomography
- Volunteers
- 8 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Multiple Sclerosis
A Study of Suboptimally Controlled Participants Previously Taking Injectable DMDs for RMS (CLICK-MS)
To evaluate the effectiveness, patient-reported outcomes (PROs) and safety of cladribine tablets in participants with relapsing forms of multiple sclerosis (RMS) including relapsing-remitting multiple sclerosis (RRMS) and active…
- Trial name
- NCT03933215
- Testing
- Cladribine
- Where
- 18 sites in United States
- Volunteers
- 100 people
- Sponsor
- EMD Serono Research & Development Institute, Inc.
Low Birthweight, Pre-Term
Low-birthweight Infant Feeding Exploration
Globally, 15% of all babies, amounting to 20 million infants each year, are born low birthweight (LBW), defined less than 2500 grams (5.5 lbs).
- Trial name
- LIFE (NCT04002908)
- Where
- 3 sites in India, Malawi and 1 more
- Volunteers
- 3,188 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Hemorrhage, Coagulation Delay
Evaluation of Novel Point of Care Coagulation System in Pregnant Women
In this study the investigators will evaluate a new point of care Quantra Hemostasis Analyzer system to assess coagulation rapidly with ease.
- Trial name
- CCPW (NCT04301193)
- Testing
- Quantra Analyzer
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
SARS-CoV-2, Covid19
Assessing the Mother-to-infant Transmission Capabilities of COVID-19 Infection Among Pregnant Women in Ontario, Canada
In order to assess the mother-to-infant and potential vertical transmission of SARS-CoV-2 infection in pregnant women, maternal and neonatal biological samples were prospectively collected from women with confirmed or suspected…
- Conditions
- SARS-CoV-2, Covid19, Corona Virus Infection, Infectious Disease Transmission, Vertical
- Trial name
- COPE (NCT04913948)
- Testing
- No intervention
- Where
- 12 sites in Canada
- Volunteers
- 246 people
- Sponsor
- Ottawa Hospital Research Institute
Hearing Loss
Pediatric Performance and Satisfaction of Oticon Medical Ponto on Softband.
The study is a non-interventional, observational, study on users of Ponto sound processors who use their sound processors on a softband solution.
- Trial name
- NCT06638840
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Oticon Medical
Cerebral Stroke
Post Marketing Study to Evaluate the NIMBUS Device
A post-market study evaluating the NIMBUS Device in acute ischemic stroke patients with confirmed intracranial large vessel occlusion.
- Trial name
- SPERO (NCT03898960)
- Testing
- NIMBUS Device
- Where
- 2 sites in Germany, Sweden
- Volunteers
- 54 people
- Sponsor
- Neuravi Limited
Lung Diseases, Interstitial
INREAL - Nintedanib for Changes in Dyspnea and Cough in Patients Suffering From Chronic Fibrosing Interstitial Lung Disease (ILD) With a Progressive Phenotype in Everyday Clinical Practice: a Real-world Evaluation
The primary objective of this observational study is to investigate the correlation between changes from baseline at 52 weeks in forced vital capacity (FVC) and changes from baseline at 52 weeks in dyspnea score points or cough…
- Trial name
- INREAL (NCT04702893)
- Testing
- Nintedanib
- Where
- 21 sites in Germany
- Volunteers
- 108 people
- Sponsor
- Boehringer Ingelheim
Influenza Virus Infection Transmission in Humans
Evaluating Modes of Influenza Transmission Observational Study of Community Acquired Influenza
The recent swine origin influenza pandemic (2009), new emergence of swine origin H3N2v, and delayed availability of vaccine for these agents highlight the need to test and optimize public health intervention strategies to reduce…
- Trial name
- EMIT (NCT01769430)
- Testing
- Observational Study of influenza aerosol shedding -- No Intervention
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- University of Maryland, College Park
Metastatic Brain Tumor, Primary Brain Tumor
Laser Ablation of Abnormal Neurological Tissue Using Robotic NeuroBlate System
The NeuroBlate® System (NBS) is a minimally invasive robotic laser thermotherapy tool that is being manufactured by Monteris Medical.
- Conditions
- Metastatic Brain Tumor, Primary Brain Tumor, Epileptic/Seizure Foci, Movement Disorders
- Trial name
- LAANTERN (NCT02392078)
- Testing
- NeuroBlate System
- Where
- 26 sites in United States
- Volunteers
- 1,153 people
- Sponsor
- Monteris Medical
Chronic Disease, Multi-morbidity
Minnesota Care Coordination Effectiveness Study
Medical care has improved greatly over the past 50 years. Treatments for most medical conditions can help us lead longer and healthier lives, but there are still problems.
- Conditions
- Chronic Disease, Multi-morbidity, Care Coordination
- Trial name
- MNCARES (NCT04957979)
- Testing
- Nursing/Medical Model of Care Coordination, Medical/Social Model of Care Coordination
- Where
- 3 sites in United States
- Volunteers
- 25,507 people
- Sponsor
- HealthPartners Institute
Relapsing-remitting Multiple Sclerosis
COMparison Between All immunoTherapies for Multiple Sclerosis.
The overarching goal of this study is to determine whether rituximab (RTX) offers effectiveness and safety advantages over other commonly used approved Disease-Modifying Drugs (DMT) in the largest real-world population-based…
- Trial name
- COMBAT-MS (NCT03193866)
- Testing
- Rituximab
- Where
- Sweden
- Volunteers
- 3,526 people
- Sponsor
- Karolinska Institutet
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