Clinical trials: sponsored by Al-Azhar University
Osteo Arthritis Knee, Varus Knee
The Effect of Body Mass Index on Short-term Results of HTO
The knee joint plays a major role in weight transmission of the body in day-to-day activities. The biomechanics of the knee and malalignment in lower limb anatomy are major risk factors for chronic knee pain, leaving Total Knee…
- Trial name
- NCT06590818
- Testing
- High tibial osteotomy (HTO
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Egymedicalpedia
Erectile Dysfunction, Sexual Dysfunction
Male Sexual Function and Sexual Quality of Life in Polygamous Versus Monogamous Marriages
This web-based comparative cross-sectional survey will assess sexual function, sexual quality of life, psychological status, and marital satisfaction among Egyptian men in monogamous and polygamous marriages.
- Trial name
- NCT07783958
- Testing
- Monogamous marital structure, Polygamous marital structure
- Where
- Egypt
- Volunteers
- 1,820 people
- Sponsor
- Al-Azhar University
To Evaluate the Effectiveness of Intra-canal Nano-ketrolac as a Medicament in Reducing Post-endodontic Pain in Patients Undergoing Root Canal Treatment
The Effect of Intra-Canal Ketorolac Application on Post-Endodontic Pain
After obtaining informed consent, the procedure begins with the administration of local anesthesia to ensure patient comfort. A standard approach involves using 2% lidocaine with 1:100,000 epinephrine, delivered either via…
- Trial name
- Post-Endodonti (NCT07064083)
- Testing
- intracanal nano-ketrolac, ketrolac gel
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Primary Monosymptomatic Nocturnal Enuresis
Bedtime Device Restriction and Desmopressin in PMNE.
This randomized controlled trial will evaluate whether restricting bedtime digital-device use improves the response to desmopressin in children with primary monosymptomatic nocturnal enuresis.
- Trial name
- NCT07776977
- Testing
- Desmopressin, Bedtime digital-device restriction
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Al-Azhar University
Kidney Stone, Retrograde Intrarenal Surgery
Ureteral Stenting After Retrograde Intrarenal Surgery for Renal Stones
Several studies evaluated the benefit of a short-term external ureteral catheter (UC) compared to double-J (DJ) ureteral stent after flexible ureteroscopy (URS); the results were controversial.
- Conditions
- Kidney Stone, Retrograde Intrarenal Surgery, Ureteral Stent
- Trial name
- NCT05738304
- Testing
- Retrograde intrarenal surgery with external ureteral catheter, Retrograde intrarenal surgery with double J internal ureteral stent
- Where
- Egypt
- Volunteers
- 250 people
- Sponsor
- Al-Azhar University
Renal Calculi
Role of Pre-stenting Before Retrograde Intrarenal Surgery With Miniaturized Flexible Ureteroscopes
This prospective randomized controlled trial will compare retrograde intrarenal surgery performed after routine preoperative ureteral stenting with direct retrograde intrarenal surgery without planned preoperative stenting in…
- Trial name
- NCT07773090
- Testing
- Preoperative double-J ureteral stenting followed by retrograde intrarenal surgery, Direct retrograde intrarenal surgery without planned preoperative ureteral stenting
- Where
- Egypt
- Volunteers
- 270 people
- Sponsor
- Al-Azhar University
Vasculogenic Erectile Dysfunction
Endothelial Markers and Tadalafil Response
This prospective cohort study will recruit eligible men attending the Urology/Andrology outpatient clinic. Baseline assessment will include demographic and clinical data, cardiovascular risk assessment, erectile-function…
- Trial name
- NCT07773103
- Testing
- Tadalafil 5mg
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Al-Azhar University
Streptococcus Mutans Count, Salivary pH
Clinical Performance, Streptococcus Mutans Count, and Salivary pH for Cention-N, Zirconomer, and Resin-modified Glass Ionomer in Class I Restoration of Primary Molars
This study will evaluate the clinical performance, Streptococcus mutans count, and salivary pH for Cention-N, Zirconomer, and resin-modified glass ionomer in Class I restoration of primary molars.
- Conditions
- Streptococcus Mutans Count, Salivary pH, Cention-N, Zirconomer
- Trial name
- NCT07776912
- Testing
- Cention-N, Zirconomer, Resin-Modified Glass Ionomer
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Galal Ali Mohamed Ebaid
Periodontal Intrabony Defects, Stage III Grade B Periodontitis
Sub-junctional Pinhole Technique
Pinhole Regenerative Therapy (PRT) following minimally invasive non-surgical periodontal therapy (MINST) in the treatment of intrabony defects associated with Stage III Grade B periodontitis.
- Trial name
- PRT (NCT07763223)
- Testing
- Sub-junctional Pinhole Technique (S-PHT)
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Acne
577-nm Diode Laser in the Treatment of Non -Inflammatory Acne
The aim of this study is to evaluate the clinical efficacy and safety of the 577 nm diode laser in the treatment of non -inflammatory acne.
- Trial name
- NCT06909344
- Testing
- 577 nm Diode laser
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Metformin Gel, Bone Healing
Effect of Metformin Gel on Guided Bone Regeneration Around Immediate Dental Implant at Posterior Maxillary Region
To evaluate, by standardized radiographic follow-up, whether locally delivered 1% metformin gel improves bone healing around immediately placed dental implants augmented with GBR.
- Conditions
- Metformin Gel, Bone Healing, Guided Bone Regeneration, Crestal Bone Loss
- Trial name
- MET-GBR (NCT07770087)
- Testing
- Metformin 1% Topical Gel, immediate Dental Implant Placement With Guided Bone Regeneration
- Where
- 2 sites in Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Renal Stone Disease, Ureteral Stricture
Long-term Safety of UAS-assisted vs Sheathless RIRS in Non-prestented Patients
This retrospective comparative cohort study will include adult patients who underwent primary RIRS for renal stones ≤20 mm at Al-Azhar University Hospitals between January 2020 and December 2025.
- Conditions
- Renal Stone Disease, Ureteral Stricture, Hydronephrosis, Urolithiasis
- Trial name
- NCT07767773
- Testing
- Ureteral access sheath-assisted RIRS, Sheathless RIRS
- Where
- Egypt
- Volunteers
- 1,200 people
- Sponsor
- Al-Azhar University
Urethral Stricture
Factors Predicting Urethral Stricture Recurrence After Dorsal Onlay Augmented, Buccal Mucosal Graft Urethroplasty
In this observational study, the investigators will evaluate potential risk factors associated with urethral stricture recurrence after augmentation anterior urethroplasty using dorsal onlay buccal mucosal Graft during the past…
- Trial name
- NCT04357080
- Testing
- Urethroplasty
- Where
- Egypt
- Volunteers
- 266 people
- Sponsor
- Al-Azhar University
Kidney Calculi, Radiation Exposure
Safety and Efficacy of Fluoroscopy-free Technique During Retrograde Intrarenal Surgery for Renal Stones
Aiming to reduce radiation exposure to patients and physicians, the investigators conduct this study protocol to evaluate the possibility of performing retrograde intrarenal surgery (RIRS) under direct visualization without…
- Conditions
- Kidney Calculi, Radiation Exposure, Retrograde Intrarenal Surgery
- Trial name
- NCT05269108
- Testing
- Fluoroscopy-free RIRS, Standard RIRS
- Where
- Egypt
- Volunteers
- 503 people
- Sponsor
- Al-Azhar University
Renal Stone, Percutaneous Nephrolithotomy
Mini-PNL, RIRS, and ESWL for Treatment of Medium-Sized, High-Density, Non-Lower Pole, Renal Stones
The optimal management of medium-sized renal stones remains quite challenging and continues to be contested. In the present study, the investigators will compare mini-PNL, RIRS and SWL in the treatment of non- lower pole, medium…
- Conditions
- Renal Stone, Percutaneous Nephrolithotomy, Retrograde Intrarenal Surgery, Extracorporeal Shockwave Lithotripsy
- Trial name
- NCT04856722
- Testing
- mini-PNL, RIRS, SWL
- Where
- Egypt
- Volunteers
- 253 people
- Sponsor
- Al-Azhar University
Renal Stone, Extracorporeal Shockwave Lithotripsy
Mini- Percutaneous Nephrolithotomy Versus Extracorporeal Shock Wave Lithotripsy for High Density Renal Stones
Several studies were conducted to compare extracorporeal shockwave lithotripsy (SWL) and percutaneous nephrolithotomy (PNL) as treatment options for medium size lower caliceal high dense stones.
- Conditions
- Renal Stone, Extracorporeal Shockwave Lithotripsy, Percutaneous Nephrolithotomy
- Trial name
- NCT04346134
- Testing
- mini-PNL, SWL
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Al-Azhar University
Erectile Dysfunction, Metabolic Syndrome
Lifestyle Modification for Erectile Dysfunction in Men With Metabolic Syndrome
Metabolic syndrome is associated with erectile dysfunction through obesity, insulin resistance, abnormal blood lipids, high blood pressure, and impaired blood-vessel function.
- Trial name
- LIFE-MetS-ED (NCT07758842)
- Testing
- Structured Lifestyle Modification Program
- Where
- 2 sites in Egypt
- Volunteers
- 55 people
- Sponsor
- Al-Azhar University
Implant Complication
This Study Will be Directed Toward Evaluating Peri-implant Tissue Behavior, Pink Esthetic Score, Patient Satisfaction and Marginal Accuracy Associated With Biologically Oriented Preparation Technique for Implant Supported Crowns.
patients will be divided into two groups (n=10) according to the type of abutment used: Group (1): will receive conventional shoulder abutment.
- Trial name
- NCT07760064
- Testing
- customized biologically oriented prepared implant abutment
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Kholoud Mohamed Mahmoud Soliman
Renal Calculi, Renal Anomaly
RIRS for Treatment of Stones in Congenital Anomalous Kidneys
The anatomic renal abnormalities like altered spatial relations with adjacent organs, abnormal calyceal orientation, and anomalous vascular patterns make the active treatment of stones in the congenitally malformed kidney a great…
- Trial name
- NCT05240170
- Testing
- RIRS, SWL
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Al-Azhar University
Chronic Neck Pain
Diaphragmatic Myofascial Release Added to Neck Exercises for Chronic Neck Pain
Chronic neck pain can affect daily activities and may be associated with pain, disability, fear of movement, and fatigue. Exercise is commonly used to manage chronic neck pain, but some people continue to experience symptoms…
- Trial name
- DMR-CNP (NCT07761793)
- Testing
- Neck Exercise Program, Diaphragmatic Myofascial Release and Diaphragm-Directed Manual Therapy
- Where
- Palestinian Territories
- Volunteers
- 60 people
- Sponsor
- Abdelrahman Alghoul