Clinical trials: sponsored by University of Calgary
Cardiovascular Diseases, Hypertension
U-CHAMP: Urban Cardiovascular Health Assessment and Management Program
High blood pressure, elevated blood glucose and high cholesterol are related to the increased risk of stroke and heart disease. Many studies have shown that this risk can be significantly reduced by lowering blood pressure, blood…
- Conditions
- Cardiovascular Diseases, Hypertension, Hyperlipidemia, Hyperglycemia
- Trial name
- U-CHAMP (NCT00626041)
- Testing
- participant referral to primary care network physician
- Where
- 2 sites in Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Impaired Glucose Tolerance, Type 2 Diabetes
Effect of Increased Intake of Low Fat Dairy Products on Weight Loss and Insulin Resistance
The purpose of this study is to determine if increased intake of low-fat milk products and calcium as part of a calorie restricted diet helps achieve a healthier body weight and body composition and decrease blood glucose levels…
- Conditions
- Impaired Glucose Tolerance, Type 2 Diabetes, Metabolic Syndrome
- Trial name
- NCT00564551
- Testing
- High dairy and calcium intake, Usual intake
- Where
- Canada
- Volunteers
- 49 people
- Sponsor
- University of Calgary
ACL Reconstruction
Home Vs. Physiotherapy Supervised Rehabilitation After ACL Reconstruction
This study was designed to determine whether or not there were any differences in knee range of motion, both statically and during gait, sagittal plane knee laxity, and quadriceps and hamstrings strength in patients three months…
- Trial name
- NCT00564837
- Testing
- Home-based rehabilitation program, Physiotherapy-supervised rehabilitation program
- Where
- Canada
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Diabetic Neuropathies
Efficacy Study of Nabilone in the Treatment of Diabetic Peripheral Neuropathic Pain
Neuropathic pain occurs as a result of damage or disease of the peripheral or central nervous system. Regardless of its cause, neuropathic pain (NeP) leads to a characteristic clinical picture characterized by ongoing pain with…
- Trial name
- NCT01035281
- Testing
- Nabilone, flexible dosing
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Chronic Rhinosinusitis
Effect of Sinufoam-Dexamethasone Mixture on Post Endoscopic Sinus Surgery Outcomes
Dexamethasone added to sinufoam, which is placed in the ethmoid cavity at the completion of endoscopic sinus surgery, will improve sinonasal mucosal healing.
- Trial name
- NCT01024075
- Testing
- Dexamethasone, Saline
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Calgary
Epistaxis
Minimally Invasive Control of Epistaxis (MICE)
Epistaxis is a common disorder with 60% of the population suffering from one episode and 10% of these cases requiring medical attention.
- Trial name
- MICE (NCT00666471)
- Testing
- MICE, SPA ligation
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- University of Calgary
Chronic Sinonasal Symptoms
The Use of Oral N-Acetyl Cysteine for the Treatment of Chronic Sinonasal Symptoms
Chronic sinonasal symptoms (CSNS), such as coughing, throat clearing, nasal obstruction, crusting, dryness and discharge are extremely common in the general population.
- Trial name
- NCT00866866
- Testing
- N-Acetyl Cysteine
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Brain Injuries, Traumatic
Proteomics of Severe Traumatic Brain Injury: A Feasibility Study
The purpose of this study is to: 1. Determine the temporal course of matrix metalloproteinase (MMP) expression in patients wiht severe traumatic brain injury 2.
- Trial name
- NCT00522496
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- University of Calgary
Neuropathic Pain
Intravenous Immunoglobulin (IVIG) for Resistant Neuropathic Pain
This project addresses a vexing problem that has alluded the best efforts of the medical/scientific community: treatment of resistant neuropathic pain.
- Trial name
- NCT00850005
- Testing
- Intravenous immunoglobulin, Normal Saline
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Calgary
Pathological Gambling
Minimal and Brief Treatments for Pathological Gamblers
The purpose of the study is to examine whether problem gamblers who receive therapy calls in addition to a self-help manual will be more likely to quit or cut back on their gambling when compared with problem gamblers who receive…
- Trial name
- NCT00203645
- Testing
- Self-help treatment
- Where
- Canada
- Volunteers
- 312 people
- Sponsor
- University of Calgary
Achilles Tendinopathy, Achilles Tendon Enthesopathy
Treatment for Achilles Tendinopathy
The purpose of this study is to determine whether sclerotherapy using a 25% dextrose and 1% lidocaine solution is an efficacious treatment for patients with chronic Achilles tendinopathy who have failed a home based, heavy load…
- Conditions
- Achilles Tendinopathy, Achilles Tendon Enthesopathy, Mid-Portion Achilles Tendinopathy, Insertional Achilles Tendinopathy
- Trial name
- NCT00835939
- Testing
- 25% Dextrose and 1% Lidocaine, Lidocaine, sclerotherapy
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Bradycardia, Atrial Fibrillation
Atrial Pacing for Termination and Prevention of Atrial Fibrillation
Atrial fibrillation (AF) is the most common sustained arrhythmia and is associated with substantial morbidity and mortality. Present treatment strategies are aimed at termination of AF and prevention of AF recurrence using…
- Trial name
- NCT00123344
- Testing
- AT501 pacemaker
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University of Calgary
Atherosclerosis
High-Density Lipoprotein (HDL) Modulation and Endothelial Function
It is well known that lowering low-density lipoprotein (LDL) (bad cholesterol) is beneficial for decreasing heart attacks and death. More recently, focus has been on trying to raise HDL (good) cholesterol.
- Trial name
- NCT00150722
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- University of Calgary
Diabetes Mellitus
Glitazones and Endothelial Function (GATE)
The purpose of the study is to determine if the addition of rosiglitazone to subjects with fair glucose control on other oral agents improves endothelial function, a surrogate marker of vascular health.
- Trial name
- NCT00203632
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Calgary
Cystic Fibrosis, Osteoporosis
Study of Alendronate to Prevent and Treat Osteoporosis in Cystic Fibrosis Patients
The primary objective of this study is to determine efficacy of 70 mg alendronate once weekly compared to placebo. This will be measured by percent changes in lumbar spine(LS) bone mineral density(BMD) in adult cystic…
- Conditions
- Cystic Fibrosis, Osteoporosis, Bone Diseases, Metabolic
- Trial name
- NCT00157690
- Testing
- Alendronate
- Where
- 6 sites in Canada
- Volunteers
- 56 people
- Sponsor
- McMaster University
Sarcoidosis, Mediastinal Diseases
Endobronchial Ultrasonography in the Diagnosis of Sarcoidosis
Sarcoidosis is a benign, inflammatory condition which will typically involve the lungs and lymph glands in the chest. Diagnosis is often confirmed with bronchoscopic biopsy.
- Trial name
- NCT00373555
- Testing
- Bronchoscopy
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Calgary
Prostate Cancer
A Randomized Trial of External Beam Radiotherapy Versus Cryoablation in Patients With Localized Prostate Cancer
A trial to determine if cryoablation is as effective as radiation in the treatment of men with localized prostate cancer.
- Trial name
- NCT00489060
- Testing
- Cryoablation and External Beam Radiation
- Where
- Canada
- Volunteers
- 244 people
- Sponsor
- University of Calgary
Type 1 Diabetes Mellitus, Hypoglycemia
Skittles(TM) Effective for Treating Hypoglycemia in Children With Type 1 Diabetes
The purpose of this study is to determine the most effective treatment option for managing naturally occurring hypoglycemia in children with type 1 diabetes. Hypotheses: 1.
- Trial name
- NCT00706693
- Testing
- Ingestion of BD glucose tablets (TM), Ingestion of Skittles (TM), Ingestion of Fruit to Go (TM)
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- University of Calgary
Obstructive Sleep Apnea
Coblation-Tonsillotomy vs Electrocautery-Tonsillectomy for the Treatment of Obstructive Sleep Apnea (OSA) in Children
Removal of the adenoid and tonsils, known as an adenotonsillectomy (AT) is one of the most frequently performed surgical procedures in North America.
- Trial name
- NCT00694772
- Testing
- Electrocautery-tonsillectomy, Coblation-tonsillotomy
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Calgary
Obesity
Prebiotic Fiber as a Modifier of Satiety Hormones and Body Weight in Overweight and Obese Adults
The purpose of this study is to determine if oligofructose supplementation promotes weight loss in overweight and obese adults.
- Trial name
- NCT00522353
- Testing
- Oligofructose
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Calgary