Clinical trials: sponsored by University of Toronto
Pain
Evaluating Lanolin for the Treatment of Nipple Pain Among Breastfeeding Women
The purpose of this study is to evaluate the effectiveness of lanolin for the treatment of painful/damaged nipples among breastfeeding women, and to evaluate if the use of lanolin has an effect on breastfeeding outcomes such as…
- Trial name
- LanP (NCT01420419)
- Testing
- Lanolin, Standard (usual) in-hospital and community postpartum care
- Where
- Canada
- Volunteers
- 186 people
- Sponsor
- University of Toronto
Hypertension
Attitudes and Understanding of Sodium Claims on Food Labels
Sodium-related claims on food labels should help people find lower sodium food choices; however consumer attitudes and understanding of such claims are unknown.
- Trial name
- NCT01764724
- Testing
- Mock package questionnaire
- Where
- Canada
- Volunteers
- 987 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Type 2 Diabetes, Cardiovascular Disease
Effect of Nuts vs. a Wheat Bran Muffin in Type 2 Diabetes
To determine if tree nuts (Almonds, Hazelnuts, Pistachios, Peanuts, Macadamia nuts, Pecans, Walnuts and Cashews) improve glycemic control in type 2 diabetes, as assessed by HbA1c and serum fructosamine, and to assess whether…
- Conditions
- Type 2 Diabetes, Cardiovascular Disease, Diet Therapy
- Trial name
- NCT00410722
- Testing
- Whole wheat and bran muffin, Mixed tree nuts
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- University of Toronto
Immunization
Testing Educational Materials in a Paediatric Setting
Immunization procedures are a common source of iatrogenic pain for infants. A recently developed clinical practice guideline, led by Taddio et al., created evidence-based strategies for management of immunization pain.
- Trial name
- NCT01713322
- Testing
- Pain management education, No pain management education
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Toronto
HIV Infections, Lipodystrophy
Raltegravir Therapy for Women With HIV and Fat Accumulation
Ritonavir-boosted protease inhibitor (PI) regimens have become a backbone for treatment of people with HIV. However, adverse drug effects, particularly lipodystrophy/lipoatrophy are closely associated with these regimens.
- Trial name
- NCT00656175
- Testing
- raltegravir
- Where
- 5 sites in United States, Canada
- Volunteers
- 39 people
- Sponsor
- University of California, Los Angeles
Pregnancy, Childbirth and the Puerperium
A Pilot Randomized Controlled Trial of Repeated Hands-and-Knees Positioning During Labour
The investigators designed a pilot randomized controlled trial to assess the feasibility and acceptability of repeated hands-and-knees positioning during labour.
- Trial name
- LPT2 (NCT01720004)
- Testing
- Repeated hands-and-knees positioning during labour
- Where
- 2 sites in United States, Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Food Intake Regulation
The Effects of Ad Libitum Pre-Meal Raisin Snack on Satiety and Food Intake in Children
No studies have reported the effect of pre-meal snacking on raisins compared to other commonly consumed snacks on energy intake in children.
- Trial name
- NCT01712737
- Testing
- Dietary intervention
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy Infants, Immunization
A Study of Two Injection Techniques to Reduce Pain in Infants Undergoing Immunization
Immunization injections are a significant source of pain for infants. Tactile stimulation (rubbing/applying pressure) may be an effective and feasible pain-relieving intervention - it is cost neutral, and has been shown to be…
- Conditions
- Healthy Infants, Immunization, Pain Management
- Trial name
- NCT01601197
- Testing
- Tactile stimulation
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Infertility, In-vitro Fertilization
NuvaRing vs. Oral Contraceptive Pills (OCP) for In-Vitro Fertilization (IVF) Pre-treatment
The newly designed contraceptive ring, Nuvaring has a lower total steroid dose, and medications are delivered locally. It has been proven to be as safe and effective as the combined OCP in ovarian suppression and preventing…
- Trial name
- NCT01298128
- Testing
- NuvaRing, marvelon
- Volunteers
- 70 people
- Sponsor
- University of Toronto
Pressure Ulcers, Multi-disciplinary Wound Care Teams
Pressure Ulcer Multi-disciplinary Teams Via Telemedicine (PUMTT): A Trial in Long Term Care
The purpose of this study is to evaluate the effectiveness of 'enhanced' multi-disciplinary wound care teams (MDTs) vs. 'usual' care teams in Long Term Care (LTC) facilities in Ontario for the treatment of pressure ulcers.
- Conditions
- Pressure Ulcers, Multi-disciplinary Wound Care Teams, Remote Support, Digital Wound Photography
- Trial name
- PUMTT (NCT01232764)
- Testing
- Exposure to multi-disciplinary wound care team
- Where
- Canada
- Volunteers
- 137 people
- Sponsor
- University of Toronto
Postpartum Hemorrhage
Carbetocin vs. Oxytocin: In-vitro Myometrial Contractions With and Without Oxytocin Pre-treatment
The purpose of this study is to compare the ability of an isolated sample of uterine muscle tissue (in a tissue bath) to contract in the presence of various drugs.
- Trial name
- NCT01689298
- Testing
- Oxytocin, Carbetocin
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Postpartum Hemorrhage
In Vitro Myometrial Contractions in Laboring and Non-laboring Women
The purpose of this study is to compare the ability of an isolated sample of uterine muscle tissue (in a tissue bath) to contract in the presence of various drugs.
- Trial name
- NCT01689311
- Testing
- Oxytocin, Ergonovine, Prostaglandin F2alpha
- Where
- Canada
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Tuberculosis
A Knowledge Translation Intervention for TB/HIV Treatment Adherence, in Zomba District, Malawi
Despite increased emphasis on evidence based practice in recent years a gap remains between evidence and practice, particularly in resource poor countries.
- Trial name
- NCT01356095
- Testing
- Knowledge translation intervention, Palm-Plus
- Where
- Malawi
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Dignitas International
Healthy, Glucose Metabolism
Protein Concentrations in Yogurt and Satiety, Food Intake and Glycemia in Healthy Men
This study compared the effects of dairy products, including milk and yogurt, with different amounts of proteins on responses of appetite, glucose and insulin and on food intake at a meal served 120 minutes later in healthy adult…
- Trial name
- NCT01673321
- Testing
- Dietary intervention
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Diabetes Mellitus, Type 2
Plant-Based Dietary Intervention in Type 2 Diabetes
The purpose of the study is to assess whether, in individuals with type 2 diabetes, a low-fat, vegan diet improves blood glucose control more effectively than a control diet based on current American Diabetes Association (ADA)…
- Trial name
- NCT00276939
- Testing
- Low-fat, low-Glycemic Index, vegan diet
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Physicians Committee for Responsible Medicine
Attention-Deficit Hyperactivity Disorder
Working Memory Training in ADHD (The Engage Study)
The overall objective of the current study is to determine whether computerized Working Memory (WM) training will enhance WM capacity in college students with Attention Deficit Hyperactivity Disorder (ADHD).
- Trial name
- NCT01657721
- Testing
- Cogmed Working Memory Training Program
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Countermeasure Evaluation
Medium-term Bedrest Whey Protein (MEP)
The human being has shown that he can live and work in the space environment, but due to the lack of essential mechanical load on muscle and bone, the fluid-shift as well as alterations in the acid-base balance (mainly on account…
- Trial name
- MEP (NCT01655979)
- Testing
- Whey Protein + Potassium bicarbonate, Control
- Where
- Germany
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- DLR German Aerospace Center
Stroke, Hemiplegia
Treatment Protocol for Hemiplegic Shoulder Pain
The purpose of this study is to determine if a specific stretching and strengthening protocol, in addition to current standard treatment, is more effective for treating post-stroke shoulder pain than current standard treatment…
- Conditions
- Stroke, Hemiplegia, Shoulder Pain
- Trial name
- TPHSP (NCT01232218)
- Testing
- Standard education/exercises for hemiplegic shoulder pain, Three dimensional Scapular-Humeral Mobilizations
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Toronto Rehabilitation Institute
Pain
The Effect of an Individualized Education Intervention on Pain Following Inguinal Hernia Repair Surgery
Pain after inguinal hernia repair surgery is common with more than 50% of patients reporting moderate to severe acute pain following surgery.
- Trial name
- HREI (NCT01063790)
- Testing
- Individualized Education
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- University of Toronto
Anaphylaxis, Allergy
Clinical Investigation on Allergic-like Reactions and Oculo-respiratory Syndrome After the H1N1 Pandemic Vaccine
During the 2009-2010 immunization campaign against pandemic H1N1, some people reported having allergic-like reactions (anaphylaxis(a shock-like reaction), hives, swelling, etc.).
- Conditions
- Anaphylaxis, Allergy, Oculorespiratory Syndrome, Allergic-like Reactions
- Trial name
- NCT01247415
- Where
- 7 sites in Canada
- Volunteers
- 138 people
- Sponsor
- PHAC/CIHR Influenza Research Network
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