Clinical trials: sponsored by Emory University
Human Immunodeficiency Virus
Improving TelePrEP Initiation and Retention Outcomes in the US: The MISTR+ Study
This study uses a rapid randomized controlled trial (RCT) design to examine HIV pre-exposure prophylaxis (PrEP) delivered through telehealth.
- Trial name
- NCT07821671
- Testing
- No Marginal Cost Interventions, Low-Marginal Cost Interventions, Standard of Care
- Where
- United States
- Volunteers
- 223,165 people
- Sponsor
- Emory University
Achalasia
Comprehensive Esophageal Diagnostics Study
The prospective clinical trial will study muscle fibrosis in relation to lower esophageal sphincter (LES) measurements on Functional Lumen Imaging Probe (FLIP) Topography (the novel technology that utilizes impedance planimetry)…
- Trial name
- NCT04641702
- Testing
- Atropine challenge, Esophageal muscle biopsy
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Emory University
Hematopoietic Cell Transplant
Virtual Rehabilitation in HCT
Chronic GVHD (cGVHD) is a major cause of illness in patients who undergo hematopoietic transplantation (HCT). GVHD can affect any organ in the body, can require several years of treatment, and can impact the quality of life…
- Trial name
- NCT05943964
- Testing
- Virtual exercise and rehabilitation program
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Emory University
Renal Transplant Recipient
Abatacept Conversion in Kidney Transplantation
This is a single center, randomized, controlled phase 2b, conversion trial. This protocol has been developed to answer the question: Can patients be safely converted from monthly belatacept IV infusions to abatacept subcutaneous…
- Trial name
- NCT04955366
- Testing
- Belatacept, Abatacept
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Emory University
Resectable Lung Non-Small Cell Carcinoma
Proton Beam Radiation Therapy After Treatment for Resected N2 Non-Small Cell Lung Cancer
This clinical trial tests proton beam radiation therapy in patients with non-small cell lung cancer who have undergone surgical resection and have lymph nodes involving the middle of the chest.
- Trial name
- NCT06008730
- Testing
- Biospecimen Collection, Proton Beam Radiation Therapy, Radiology, Treatment Planning
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Emory University
Coronary Microvascular Dysfunction
A Plant-Based Diet in the Treatment of Coronary Microvascular Dysfunction
This study will evaluate whether a fully provided, unrefined, polyphenol-rich plant-based diet can improve blood vessel function in adults with coronary microvascular dysfunction (CMD), a condition that causes reduced blood flow…
- Trial name
- NCT07821372
- Testing
- Polyphenol-Rich Plant-Based Diet
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Emory University
Stroke, Healthy Adult
tVNS Responsiveness Testing With Pupil Size
The goal of this study is to learn about the acute pupil response to transcutaneous vagus nerve stimulation (tVNS) in stroke survivors and healthy adults.
- Trial name
- NCT06335199
- Testing
- Unilateral Left tVNS stimulation, Bilateral tVNS stimulation, Unilateral Right tVNS stimulation
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Georgia Institute of Technology
Metastatic Skin Squamous Cell Carcinoma, Recurrent Skin Squamous Cell Carcinoma
Cemiplimab Before and After Surgery for the Treatment of High Risk Cutaneous Squamous Cell Cancer
This phase I trial studies how well cemiplimab before and after surgery works in treating patients with high risk cutaneous squamous cell cancer.
- Trial name
- NCT04428671
- Testing
- Cemiplimab, Radiation Therapy, Therapeutic Conventional Surgery
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Emory University
Major Depression
Leucine in Midlife Depression
The study aims to investigate the effects of a 6-week leucine challenge on brain chemistry, connectivity, and behavior in people with midlife depression.
- Trial name
- NCT06580145
- Testing
- L-leucine, L-lysine
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Emory University
Diabetes Mellitus, Type 1
Testing an Integrated Care Model Trial
This study aims to test the use of an adapted collaborative care model for improving the health outcomes of adults diagnosed with type 1 diabetes (T1D). The duration of the study is 18 months with 4 study survey points.
- Trial name
- NCT06448429
- Testing
- Usual care, Collaborative care model (CoCM)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Emory University
Environmental Exposure
Plastic Waste and Human Health Effects in Guatemala
Ecolectivos is a type-1 hybrid-effectiveness-implementation study that uses a village-level cluster randomized controlled trial design.
- Trial name
- Ecolectivos (NCT05130632)
- Testing
- The community working group
- Where
- 2 sites in Guatemala
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Emory University
Tendinopathy
Assessing the Tendons With Shear Wave Elastography
The purpose of this study is to utilize Shear Wave Elastography (SWE) to study the viscoelastic properties of tendons to understand the functional differences between normal/asymptomatic and symptomatic tendon states.
- Trial name
- NCT03456778
- Testing
- Shear Wave Elastography
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Emory University
Influenza
A Human Influenza Transmission Study Using Naturally Infected Community Donors
The purpose of this study is to determine whether influenza A or B can be transmitted from adults with naturally acquired community influenza infection to healthy adult recipients under controlled inpatient exposure conditions…
- Trial name
- FLU-TIDE (NCT07814495)
- Testing
- Influenza Donor Visit, Influenza Recipient Inpatient Exposures Sessions
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Emory University
Hidradenitis Suppurativa (HS)
Botulinum Toxin Blockade of Neuronal Signals to Immune Cells as a Novel Treatment for Hidradenitis Suppurativa
This study will build on data from mice and humans implicating TRPV1 nociceptors in the pathogenesis of the type-17 chronic inflammatory skin disease hidradenitis suppurativa (HS).
- Trial name
- Botox in HS (NCT07756346)
- Testing
- Botulinum Toxin A (Allergan, Inc, Irvine CA)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Massachusetts, Worcester
Sickle Cell Disease
Assessing Molecular Mechanisms and Effects of Music Therapy in Youth With Sickle Cell Disease Using Single-cell RNA-sequencing
The goal of this clinical trial is to evaluate whether a 4-week music therapy (MT) intervention can reduce chronic pain and improve psychosocial outcomes in youth with sickle cell disease (SCD).
- Trial name
- NCT07562451
- Testing
- Music Therapy, Standard of Care
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Emory University
Organ Transplantation, Transplantation Immunology
Immune Monitoring and Assay Development in Organ Transplant Recipients
The purpose of this study to develop a well-characterized library of blood, biopsy tissue, and urine samples from transplant patients. Subjects without transplants will also be enrolled for comparison.
- Trial name
- IMP (NCT01283295)
- Where
- 2 sites in United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Emory University
Post-Acute COVID-19 Syndrome
REVERSE-Long COVID-19 With Baricitinib Study
REVERSE-LC is a phase 3 trial of baricitinib versus placebo in adults with neurocognitive impairment (a form of Alzheimer's Disease and Related Dementias or ADRD) or cardiopulmonary symptoms due to Long COVID.
- Trial name
- REVERSE-LC (NCT05858515)
- Testing
- Baricitinib 4 MG
- Where
- 6 sites in United States
- Sponsor
- Vanderbilt University Medical Center
Parents
Father-Inclusive Parenting Intervention in Mwanza, Tanzania
This cluster-randomized controlled trial aims to evaluate the impact of a couples-based parenting program, "Familia Bora," on mothers' and fathers' parenting, couples' relationships, gender, and early child development in the…
- Trial name
- NCT07025447
- Testing
- Familia Bora
- Where
- 2 sites in United States, Tanzania
- Volunteers
- 792 people, healthy volunteers welcome
- Sponsor
- Emory University
Stroke
Biomechanical and Neural Mechanisms of Post-stroke Gait Training
The study seeks to develop an understanding of how, why, and for whom fast treadmill walking (Fast) and Fast with functional electrical stimulation (FastFES) induce clinical benefits, allowing future development of cutting-edge…
- Trial name
- NCT04380454
- Testing
- Functional electrical stimulation (FES), Fast treadmill walking
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Emory University
Psychological Trauma
The PREVENT Resilience Study
PTSD is one of the most universal and severe psychiatric disorders whose incidence continues to rise due to the common exposure to severe trauma in the United States and worldwide.
- Trial name
- NCT07568145
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Emory University
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