Clinical trials: sponsored by Shirley Ryan AbilityLab
Spinal Cord Injury
Arm and Leg Cycling for Accelerated SCI Recovery
The purpose of this study is to examine interventions with paradigms involving upper and lower extremity cycling (A\&L cycling) with A\&L cycling with functional electrical stimulation (FES) (A\&L_FES group), A\&L cycling with…
- Trial name
- NCT06873776
- Testing
- A&L cycling, Body weight supported treadmill training (BWSTT)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Shirley Ryan AbilityLab
Amputation
Development and Usability of an Adjustable Prosthesis for Aquatic Therapy
The initial purpose of this study is to develop a prosthesis which is adjustable to use with a variety of patients in aquatic therapy. Aquatic therapy is a beneficial rehabilitation tool for individuals with limb loss.
- Trial name
- NCT06259695
- Testing
- Adjustable Aquatic Therapy Prosthesis
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injuries, Poliomyelitis
Comparing Functional Outcomes in Individuals Using Micro-processor Controlled Orthosis Versus Stance Control Orthosis
The study will specifically evaluate the potential of the C-Brace to improve the functional mobility and quality of life in individuals with lower extremity impairments due to neurologic or neuromuscular disease, orthopedic…
- Conditions
- Spinal Cord Injuries, Poliomyelitis, Post-polio Syndrome, Arthritis
- Trial name
- NCT02089880
- Testing
- C-brace, Stance control orthosis
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke
Bilateral Priming Plus Task Specific Training for Severe Upper Limb Hemiparesis
The purpose of the study is to determine the best treatment for the arm that has been affected by a stroke. The investigators plan to determine if the arm affected by a stroke will improve with a combination of motor priming and…
- Trial name
- NCT03517657
- Testing
- Bilateral Motor Priming + Task Specific Training (BMP + TST), Control Priming + TST (CP + TST)
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Northwestern University
COVID-19, Healthy Control
Wearable Sensor to Monitor COVID-19 Like Signs and Symptoms
1. Develop a wearable sensor package to gather data on COVID-19-like signs and symptoms such as elevated body temperature, respiratory parameters, heart rate ,cough and gait. 2.
- Trial name
- NCT04393558
- Testing
- ADAM Sensor
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke, Cerebral Vascular Accident
Safety and Feasibility of ExoNET
The purpose of this study is to evaluate the safety, feasibility, and preliminary efficacy of the ExoNET passive robotic device.
- Trial name
- NCT05180812
- Testing
- ExoNet Tuned to Gravity Support
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Shirley Ryan AbilityLab
Cerebral Palsy
Development of a Robotic Ankle Assist Device
The overall objectives of this work is to establish feasibility of a robotic ankle assist device (RAAD) to improve mobility in free-living settings and to establish the RAAD as an effective tool to provide increased dose and…
- Trial name
- NCT04516343
- Testing
- Robotic Ankle Assist Device (RAAD)
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- BiOMOTUM, Inc.
Spinal Cord Injuries, Cervical Spinal Cord Injury
Neurostimulation for Respiratory Function After Spinal Cord Injury
The purpose of this research study is to learn more about the connections between the brain, nerves, and diaphragm after experiencing a cervical spinal cord injury (SCI).The main question it aims to answer is: Changes in…
- Conditions
- Spinal Cord Injuries, Cervical Spinal Cord Injury, Respiratory Function Impaired
- Trial name
- NCT05756894
- Testing
- Neurostimulation, Repiratory training
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Shirley Ryan AbilityLab
Severe Stroke or Similar Neurological Muscle Weakness
Mobility Training Using Exoskeletons for Functional Recovery After Stroke
The purpose of this study is to assess the safety and effectiveness of the Ekso robotic exoskeleton in persons affected by a severe stroke.
- Trial name
- NCT02128152
- Testing
- Ekso exoskeleton
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke
Ankle Exosuit Training in the Clinic to Community Community
This study focuses on investigating exosuit technology by evaluating its ability to provide a gait-restorative effect delivered in both clinic and community settings.
- Trial name
- NCT04251091
- Testing
- Treadmill walking, Overground Walking
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Arun Jayaraman, PT, PhD
Traumatic Brain Injury
Noninvasive Vagal Nerve Stimulation and Cognitive Rehabilitation
The purpose of this study is to examine the feasibility and preliminary efficacy of using transcutaneous auricular vagus nerve stimulation (tVNS) to enhance cognitive recovery in patients with mild-moderate traumatic brain injury…
- Trial name
- NCT06589362
- Testing
- Transcutaneous auricular vagus active nerve stimulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Shirley Ryan AbilityLab
Amputation
Powered Prosthesis for Use With TF Osseointegration Recipients
The purpose of this study is to evaluate functional mobility, control, and user satisfaction from persons who have an amputation above the knee and have received osseo-integration (OI) and targeted muscle reinnervation (TMR)…
- Trial name
- NCT06160882
- Testing
- Powered Prosthesis Training and EMG data collection, Perform Osseointegration (OI) surgery and Targeted Muscle Reinnervation (TMR)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Shirley Ryan AbilityLab
Amputation, Amputation, Traumatic
GaMA Metric to Quantify Functional Importance of Various Upper Limb Prosthetic Devices
The goal of this study is to utilize the Gaze and Movement Assessment (GaMA) metric to assess the effect of different prosthetic components on compensatory movements used to complete activities of daily living.
- Conditions
- Amputation, Amputation, Traumatic, Amputation; Traumatic, Hand, Amputation; Traumatic, Limb
- Trial name
- NCT06420687
- Testing
- Clinically prescribed prosthesis, Experimental prosthesis - Wrist rotation + 1-DOF, Experimental prosthesis - Wrist rotation + Wrist flexion +1-DOF
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Phantom Limb Pain, Phantom Pain
VR to Evaluate Phantom Limb Pain
The objective of this study is to develop a virtual rehabilitation system that can be used to effectively treat Phantom Limb Pain (PLP) within the research setting and for at-home use by individuals with upper and lower extremity…
- Conditions
- Phantom Limb Pain, Phantom Pain, Phantom Sensation, Phantom Limb Syndrome With Pain
- Trial name
- NCT05915065
- Testing
- Coapt Phantom Limb Pain Management System
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injuries
Wheelchair Backs That Support the Spinal Curves
The overall objective of this fully powered clinical trial is to investigate if using a solid backrest on a manual wheelchair (MWC) will improve postural alignment, function and wheelchair mobility, as compared with an upholstery…
- Trial name
- NCT05068648
- Testing
- Manual Wheelchair (MWC) backrest configuration
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Craig Hospital
Stroke, Cerebral Vascular Accident
Safety and Feasibility of an ExoNET for Supination Assistance for Stroke Survivors
The purpose of this study is to evaluate the safety, feasibility, and efficacy of an exoskeletal network of passive, multi-joint springs for forearm supination.
- Trial name
- NCT06655636
- Testing
- Device tuned to Assistance, Device tuned to Anti-Assistance
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Stroke
R01.Aim 2.Study 1: IsoReach
To determine the effects of 3D isometric movement training in healthy participants and impaired participants due to a stroke.
- Trial name
- NCT06656754
- Testing
- Isometric Reaching
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Amputation, Neuropathy
Somatosensation Device Trial
This research is being done to test a new device, called the Somatosensation Device, with people who have either a below knee amputation, or neuropathy (i.e. decreased sensation) in their legs.
- Trial name
- NCT06168396
- Testing
- Somatosensation Device, Baseline
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Shirley Ryan AbilityLab
Exercise Therapy, Heart Rate Determination
Assessing Visual Feedback of HR Monitoring in Rehabilitation - Pilot
Monitoring heart rate during exercise can provide feedback to the patient and provider that the patient is exercising in the appropriate, individualized and safe range for them.
- Trial name
- NCT05273801
- Testing
- Heart Rate Recording from Multiple Participants, No Visual Feedback, Visual Feedback of Multiple Participant Heart Rates
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Shirley Ryan AbilityLab
Disabled Persons
Mindfulness, Exercise, and Nutrition To Optimize Resilience (MENTOR)
The Mindfulness, Nutrition and Exercise to Optimize Resilience (MENTOR) program is offered through the National Center on Health, Physical Activity and Disability (NCHPAD).
- Trial name
- MENTOR (NCT06560619)
- Testing
- MENTOR
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Shirley Ryan AbilityLab