Clinical trials: sponsored by Al-Azhar University
Primary Teeth Indicated for Pulp Therapy
Effect of Graphene Oxide on Vital and Non-Vital Primary Teeth Compared to the Conventional Techniques
The null hypothesis of the current study suggested that there will be no significant difference regarding the effect of Graphene Oxide (GO), Lesion sterilization and tissue repair (LSTR) and Zinc Oxide and Eugenol on the clinical…
- Trial name
- NCT07424053
- Testing
- Graphene Oxide using vital pulpotomy technique, MTA using vital pulpotomy technique, Zinc Oxide and Eugenol using vital pulpotomy technique
- Volunteers
- 126 people
- Sponsor
- Al-Azhar University
Displaced Fracture Neck Femur, Total Hip Arthroplasty (THA)
Total Hip Arthroplasty Versus Bipolar Hemiarthroplasty for Treatment of Intracapsular Displaced Fracture Neck Femur in Elderly Active Patients
Femoral neck fracture (FNF) is a worldwide health problem that can cause significant morbidity and mortality. Most femoral neck fractures are associated with a fall, and the risk factors include osteoporosis, chronic medication…
- Conditions
- Displaced Fracture Neck Femur, Total Hip Arthroplasty (THA), Bipolar Hemiarthroplasty, Elderly Active Patients
- Trial name
- NCT07409909
- Testing
- Total Hip Arthroplasty, Bipolar Hemiarthroplasty
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Posterior Root Tear of the Medial Meniscus, Arthroscopic Transtibial Pullout Suture Repair
Arthroscopic Transtibial Pullout Suture Repair Versus Suture Anchor Repair in Posterior Root Tear of the Medial Meniscus
The menisci play a fundamental role in maintaining normal knee biomechanics by distributing load, absorbing shock, providing stability, and facilitating joint lubrication.
- Conditions
- Posterior Root Tear of the Medial Meniscus, Arthroscopic Transtibial Pullout Suture Repair, Suture Anchor Repair
- Trial name
- NCT07408323
- Testing
- Arthroscopic Transtibial Pullout Suture Repair, Suture Anchor Repair
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Adhesive Capsulitis
Operative vs Non Operative Management of Adhesive Capsulitis: A Comparative Review
Adhesive capsulitis is a common disabling shoulder condition characterized by pain and progressive restriction of shoulder motion.
- Trial name
- MAC (NCT07410845)
- Testing
- Non Operative management, Operative Management (Literature-based)
- Where
- Egypt
- Volunteers
- 1 people
- Sponsor
- Al-Azhar University
Bladder Cancer Treatment
Trimodality Bladder Preservation
The aim of this study is To evaluate the outcomes of patients with muscle invasive bladder cancer managed by trimodal therapy", Neoadjuvant chemotherapy( NAC) followed by Transurethral resection of the bladder tumor then…
- Trial name
- NCT07402317
- Testing
- Transurethral resection of bladder tumor: We are aimed at Complete TURBT. Which was defined as no residual tumor, whereas incomplete TURBT
- Where
- Egypt
- Volunteers
- 97 people
- Sponsor
- Al-Azhar University
Erectile Dysfunctions
Daily Tadalafil 5 mg Combined With On-Demand Sildenafil 100 mg for Treatment of Erectile Dysfunction in PDE-5I Non Responder Patients
The goal of this clinical trial is to evaluate whether daily dosing with tadalafil 5 mg combined with on-demand sildenafil 100 mg can improve erectile function in men with erectile dysfunction (ED) who do not respond to PDE5…
- Trial name
- NCT07391579
- Testing
- Tadalafil 5 mg & Sildenafil 100mg
- Where
- 11 sites in Egypt
- Volunteers
- 500 people
- Sponsor
- Mansoura University
Cryptosporidium Infection
The Effect of Echinacea (Immulant ®) in the Treatment of CRYPTOSPORIDIOSIS in Immunocompromised Children
This study aims to: 1. To evaluate the effectiveness of Immulant ® addition to standard treatment in reducing clinical symptoms of Cryptosporidiosis in immunocompromised children. 2.
- Trial name
- NCT07388615
- Testing
- Echinacea Extract
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Appendix Diseases, Surgery
Treatment Strategy for Complicated Pediatric Appendicitis Based on Laparoscopic Surgery
Observational retrospective study included 765 children with Operative management by laparoscopic appendectomy, conservative management for appendicular mass and drainage of abscess by IR should be tried first.
- Trial name
- CALAP (NCT07385261)
- Testing
- laparoscopic appendectomy
- Where
- Egypt
- Volunteers
- 765 people
- Sponsor
- Mohammad Daboos
Three Dimensional, Dento-Skeletal
Three Dimensional Evaluation of Dento-Skeletal Effects of Leaf Self Expander in Cleft Lip and Palate Patients
This study aims to evaluate the dento-alveolar changes after maxillary expansion in cleft lip and palate patients by Leaf Self Expander, as compared to conventional Rapid Maxillary Expander using digital cast analysis and…
- Conditions
- Three Dimensional, Dento-Skeletal, Leaf Self Expander, Cleft Lip
- Trial name
- NCT07384338
- Testing
- Rapid maxillary expansion, Leaf Self Expander
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Acute Leukemia
Assessment of Antithrombin III, Protein C, Protein S and D-dimer in Acute Leukemia
The goal of this observational study is to evaluate the levels of Antithrombin III, Protein C, Protein S, and D-dimer in patients with Acute Leukemia (Acute Lymphoblastic Leukemia (ALL) and Acute Myeloid Leukemia (AML)).
- Trial name
- NCT07036809
- Testing
- Antithrombin III, Protein C, Protein S
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Muhamed Ahmed Abdelmoaty Muhamed Alhagrasy
Cesarean Section Complications
Optimal Interval Between Consecutive Cesarean Sections
The goal of this observational study is to determine the best time interval between consecutive cesarean sections and compare maternal and neonatal outcomes in women with a history of previous cesarean sections.
- Trial name
- NCT06491368
- Testing
- Cesarean Delivery
- Where
- Egypt
- Volunteers
- 201 people
- Sponsor
- Al-Azhar University
Endothelial Cell Density Loss
Endothelial Changes in Diabetic and Non-diabetic Patients Undergoing Phacoemulsification
The aim of this study is to evaluate and compare specular endothelial changes in diabetic and non-diabetic patients undergoing phacoemulsification by assessing endothelial cell density, coefficient of variation, and percentage of…
- Trial name
- NCT07369388
- Testing
- Phacoemulsification
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Al-Azhar University
Cesarean Section Complications
Ultrasonographic ONSD as a Predictor of PDPH in Spinal Anesthesia for Cesarean Delivery
The Optic Nerve Sheath Diameter (ONSD), measured non-invasively by bedside ultrasound, is a well-established surrogate for intracranial pressure (ICP), as the optic nerve sheath is continuous with the intracranial dura mater and…
- Trial name
- NCT07360756
- Testing
- Study Cohort (Single Cohort)
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Al-Azhar University
Probiotic, Ethyl Lauroyl Arginate
Probiotic-Based Versus Ethyl Lauroyl Arginate-Containing Mouthwashes on Streptococcus Mutans Counts, Dental Plaque Accumulation, and Salivary pH in a Group of Egyptian School Children
This study aims to compare the efficacy of probiotic-based mouthwashes versus ethyl lauroyl arginate-containing mouthwashes in reducing Streptococcus mutans count, dental plaque accumulation, and salivary pH among a group of…
- Conditions
- Probiotic, Ethyl Lauroyl Arginate, Mouthwashes, Streptococcus Mutans
- Trial name
- NCT07356869
- Testing
- Probiotic mouthwash, Ethyl lauroyl arginate mouthwash, Professional prophylaxis (scaling + polishing)
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Al-Azhar University
Myofascial Pain Syndrome (MPS)
High-Intensity Laser Therapy for Trapezius Myofascial Pain (HILT-TRAP Study)
This study aims to evaluate the effectiveness of optimized High-Intensity Laser Therapy (HILT) compared with sham treatment in patients with trapezius myofascial pain syndrome.
- Trial name
- HILT-TRAP Stud (NCT07352787)
- Testing
- High-Intensity Laser Therapy
- Where
- Iraq
- Volunteers
- 104 people
- Sponsor
- Neveen Abd El Maksoad Kohaf
Postoperative Analgesia of Inguinal Hernia Repair in Adults
Comparison of Quadratus Lumborum and Combined Groin Nerve Blocks for Postoperative Analgesia After Open Inguinal Hernia Repair.
This double-blind randomized controlled trial aimes to compares two ultrasound-guided regional techniques-lateral quadratus lumborum block versus combined ilio-inguinal/ilio-hypogastric/genitofemoral (II-IH-GFN) block-for…
- Trial name
- NCT07343570
- Testing
- Ultrasound-guided lateral quadratus lumborum block, Combined ilio-inguinal/ilio-hypogastric/genitofemoral (II-IH-GFN) block
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Al-Azhar University
Smoking ( Cigarette), Periodontitis Stage II
Study of Gum Tissue Proteins in Smokers vs. Non-smokers After Cleaning
The aim of this study is to evaluate how smoking affects the healing process of the gums after treatment. The researchers will measure the levels of two specific proteins (PLAP-1 and Sclerostin) in the gum fluid of patients with…
- Trial name
- NCT07339670
- Testing
- Non Surgical Periodontal Treatment includes post operative mouth wash with Listerine® (ethanol 21.6%, methyl salicylate 0.06%, menthol 0.042%, thymol 0.064% and eucalyptol 0.092%)
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Al-Azhar University
Vital Pulp Therapy in Young Permanent Tooth
Clinical Evaluation and Cone Beam Computed Tomography Analysis of Different Biomaterials for Apexogenesis of Immature Permanent Molars
The present study will be conducted to clinically evaluation and cone beam computed tomography analysis of amniotic membrane, putty mineral trioxide aggregate and biodentine as therapeutic agents for apexogenesis of immature…
- Trial name
- MTA/CBCT (NCT07336498)
- Testing
- Vital pulp therapy of immature permanent teeth
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Al-Azhar University
Adult Pulpotomy Success in Diabetic Patients
Evaluation of the Effect of Type 2 Diabetes Mellitus on the Success of Adult Pulpotomy
The aim of the present study will be directed to evaluate the clinical and radiographic success of adult pulpotomies in type 2 diabetic and non-diabetic patients.
- Trial name
- controlled cli (NCT07332026)
- Testing
- pulpotomy
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Brachial Plexus Blocks
Perineural Dexamethasone, Dexmedetomidine, or Their Combination to Reduces Rebound Pain After Supraclavicular Brachial Plexus Block
Dexmedetomidine, an α2 adrenoceptor agonist, and dexamethasone, a potent anti-inflammatory steroid, are commonly used, effective, and safe adjuvants to peripheral nerve block (PNB).
- Trial name
- NCT07299877
- Testing
- Group A (Dexamethasone), Group B (Dexmedetomidine), Group C (Dexamethasone + Dexmedetomidine)
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Al-Azhar University