Clinical trials: sponsored by Shirley Ryan AbilityLab
Stroke, Ischemic
Marker for Stroke Recovery
This study aims to develop a neurophysiological marker for post-stroke participants that predicts upper extremity motor recovery in response to a standard upper extremity rehabilitation protocol of task-specific training (TST).
- Trial name
- NCT05256368
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Psychological Adaptation
Problem-solving: A Stroke Caregiver Early Intervention
Intervention studies for stroke caregivers (CG's) during early caregiving are few and have met with limited success. The Post-Stroke Rehabilitation Clinical Practice Guidelines (1995) recommend sensitivity to the adverse effects…
- Trial name
- CPSI (NCT01141738)
- Testing
- Caregiver Problem-Solving Intervention, Wait List Control
- Where
- 4 sites in United States
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Osteoarthritis, Knee Osteoarthritis
The Impact of a Seated Compact Elliptical Trainer on Individuals With Knee OA
Exercise is considered the most effective, non-drug treatment for reducing pain and improving movement in patients with osteoarthritis.
- Conditions
- Osteoarthritis, Knee Osteoarthritis, Arthritis, Joint Diseases
- Trial name
- NCT05857605
- Testing
- Exercise for Knee Osteoarthritis, Compact seated elliptical exercise machine- Cubii JR-1
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injuries
Robotic Exoskeleton With Functional Electrical Stimulation in Acute Spinal Cord Injury
The purpose of this study is to examine the effectiveness of mobility training using the Ekso robotic exoskeleton with functional electrical stimulation (FES) in persons affected by spinal cord injury; designated AIS…
- Trial name
- NCT04250688
- Testing
- Ekso Training with FES
- Volunteers
- 10 people
- Sponsor
- Shirley Ryan AbilityLab
COVID-19
International Validation of Wearable Sensor to Monitor COVID-19 Like Signs and Symptoms
1. Deploy wearable COVID sensor to collect high resolution physiological data (temperature, cardiac, respiratory and physical activity) from COVID positive patients. 2.
- Trial name
- NCT05334680
- Testing
- ANNE Sensor
- Where
- 3 sites in India
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Arun Jayaraman, PT, PhD
Cerebral Palsy
Transcranial Direct Current Stimulation Versus Virtual Reality on Gait in Children With Spastic Diplegia
Spastic diplegia is the most frequent type of cerebral palsy (CP), and impaired gait is a common sequela of this condition. The investigators compared the effects of two novel research interventions transcranial direct current…
- Trial name
- NCT05670522
- Testing
- Transcranial direct current stimulation, Virtual reality
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Beni-Suef University
Stroke, Aphasia
Studying Language With Brain Stimulation in Aphasia
The overall goal of this study is to evaluate whether stimulation of two brain areas alongside behavioral speech-language therapy increases connectivity to improve language functions in stroke-aphasia patients.
- Trial name
- NCT05660304
- Testing
- Cortico-cortical paired associative stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Shirley Ryan AbilityLab
Aphasia
Improving Electronic Written Communication in Aphasia
People with aphasia have difficulty with writing and often struggle to use electronic communication that connects people to one another.
- Trial name
- T-WRITE (NCT03773419)
- Testing
- Texting Intervention (T-WRITE), HandWriting Intervention (ORLA+WTG)
- Where
- 2 sites in United States
- Volunteers
- 63 people
- Sponsor
- Shirley Ryan AbilityLab
Cerebrovascular Stroke
Sub-Acute Stroke Rehabilitation With AMES
The AMES device is designed to produce functional cortical changes by:(1) assisting the subject as he/she attempts to move the limb (assisted movement) and (2) enhancing movement sensation by vibrating the muscles during movement…
- Trial name
- AMES (NCT00609115)
- Testing
- AMES device (test), AMES device (crossover)
- Where
- 5 sites in United States
- Volunteers
- 83 people
- Sponsor
- AMES Technology
Spinal Cord Injuries
Intermittent Hypoxia and Upper Extremity EMG Recordings in Individuals With Spinal Cord Injury
In this current study, the examiners examine some of the mechanisms of how Acute Intermittent Hypoxia (AIH) effects the upper extremity of survivors of spinal cord injury.
- Trial name
- NCT05513911
- Testing
- Acute Intermittent Hypoxia
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Shirley Ryan AbilityLab
Aphasia
Timing of Transcranial Direct Current Stimulation (tDCS) Combined With Speech and Language Therapy (SLT)
Aphasia is an acquired (typically left-hemisphere) multi-modality disturbance of language that impacts around 2 million people in the USA. Aphasia impacts language production and comprehension as well as reading and writing.
- Trial name
- NCT03773406
- Testing
- Offline tDCS-before therapy, Offline tDCS-after therapy, Online tDCS
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injuries
Repetitive Acute Intermittent Hypoxia for Spinal Cord Repair
Our goal is to enhance repeated exposure to acute intermittent hypoxia (rAIH)/training-induced aftereffects on upper and lower limb function recovery in humans with chronic spinal cord injury (SCI).
- Trial name
- NCT03433599
- Testing
- Repeated exposure to acute Intermittent Hypoxia (rAIH), Normal Room Air, Upper-limb Training by Research Staff
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injuries
Spasticity After Spinal Cord Injury
Very often, people who have a SCI have difficulty doing things with their arms or hands as a result of muscle stiffness , or spasticity. Spastacity can cause problems performing even the simplest of everyday tasks.
- Trial name
- NCT04393922
- Testing
- Acoustic stimuli (Startle)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Aphasia, Stroke
The Intensive Comprehensive Aphasia Program (ICAP)
The purpose of this study is to conduct a randomized clinical trial that assesses the efficacy and cost-effectiveness of an Intensive Comprehensive Aphasia Program (ICAP), specifically focusing on the variable of intensity.
- Trial name
- NCT03514186
- Testing
- Speech and Language Therapy
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Shirley Ryan AbilityLab
Mobility Limitation
Validation of a Smartphone-based Assessment of Movement Health
To correlate a smartphone-based assessment of mobility, stability, and posture with those derived from standard clinical tests among a heterogeneous cohort.
- Trial name
- NCT04854148
- Testing
- Smartphone Movement Health Assessment
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Spasticity as Sequela of Stroke, Nerve Transfers
Nerve Transfers in Post-stroke Spasticity
Stroke is nowadays a leading cause of disability with devastating sequelae. Upper limb spasticity is one of them. Nevertheless, not all the muscles are equally affected, as some may turn spastic or paretic and other remain…
- Trial name
- NCT04437056
- Testing
- Cognitive nerve transfers to spastic upper extremity muscles in stroke patients
- Where
- Austria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Hemiplegia
Atalante USAbility
The "USAbility" study - Human Factor Validation Testing of the Atalante exoskeleton aims at demonstrating that Atalante can be used by the intended users without serious use errors or problems, for the intended uses and under the…
- Trial name
- NCT05284708
- Testing
- Atalante
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wandercraft
Knee Osteoarthritis
Impact of Sensor Technology in Knee OA
OBJECTIVES: Physical activity has been established as an important component of rehabilitation for knee osteoarthritis (OA), and is often guided by a physical therapist.(1) Physical therapy for knee OA typically involves 1-3…
- Trial name
- NCT05222503
- Testing
- Knee Brace + OPUM Digital Knee, Knee Brace
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- OPUM Technologies US LTD
Geriatrics
Efficacy of Samsung GEMS-H Device Training in Older Adults
The purpose of this study is to evaluate the feasibility of using Samsung robotic hip assist-based mobility intervention for older adults with frailty.
- Trial name
- NCT05197127
- Testing
- exoskeleton-based gait training
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Brain Injuries, Traumatic
Determining the Incidence of Vestibular Dysfunction in Traumatic Brain Injury Patients
The purpose of this study is to determine the incidence of vestibular dysfunction in traumatic brain injury patients admitted to acute inpatient rehabilitation.
- Trial name
- NCT04592575
- Testing
- Vestibular Evaluation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Shirley Ryan AbilityLab