Clinical trials: sponsored by Al-Azhar University
Labour Analgesia
Effect of Epidural Needle Injection on Catheter Placement Success During Painless Labour
Epidural analgesia is the gold standard for painless labour, but successful catheter placement can be technically challenging due to anatomical and physiological changes in pregnancy.
- Trial name
- NCT07327918
- Testing
- Injection Group, Control group
- Where
- Egypt
- Volunteers
- 216 people
- Sponsor
- Al-Azhar University
Post-Spinal Shivering
Comparative Dose-Response of Intrathecal Dexmedetomidine for Post-Spinal Shivering
Dexmedetomidine, a highly selective α2-adrenergic agonist, when used intrathecally as an adjuvant to local anesthetics, prolongs sensory/motor block and may blunt thermoregulatory shivering mechanisms.
- Trial name
- NCT07327879
- Testing
- Group D2.5 (Low-Dose Dexmedetomidine Group), Group D5 (Moderate-Dose Dexmedetomidine Group), Group D10 (Higher-Dose Dexmedetomidine Group)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Al-Azhar University
Caesarean Delivery, Hypotension Postprocedural
Comparison of Classic and Sequential Spinal Techniques for Preventing Hypotension During Cesarean Delivery.
Given the clinical importance of maternal hypotension, the potential advantages of sequential spinal dosing warrant formal evaluation in a prospective, adequately powered randomized controlled trial.
- Trial name
- NCT07327866
- Testing
- Classic group, Sequential group
- Where
- Egypt
- Volunteers
- 94 people
- Sponsor
- Al-Azhar University
Odontogenic Cysts
Risk-Adapted Treatment Strategies for Odontogenic Keratocysts: A Long-Term Randomized Clinical Trial Quantifying Recurrence Reduction
Background The odontogenic keratocysts (OKCs) have been one of the maxillofacial region's most contentious pathological phenomena.
- Trial name
- OKCs (NCT06133764)
- Testing
- Enucleation+ Peripheral Ostectomy+Carnoy's solution chemical cauterization (E+CS + PO), Decompression/ marsupialization (D/M), Enucleation (E)
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- Qassim University
Malocclusion
Validation of AI-Based Cephalometric Analysis in Orthodontics
This study is designed to evaluate whether artificial intelligence can analyze cephalometric images in orthodontics as a reliable tool for diagnosis and treatment planning.
- Trial name
- AI-CEPH (NCT07315152)
- Testing
- Artificial Intelligence-Driven Cephalometric Analysis
- Where
- Egypt
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Cataract Surgery Anesthesia
The Use of Sublingual Melatonin Premedication in Geriatric Cataract Surgery
Cataract surgery is routinely performed with anesthesia care, whereas anesthesia care for other elective, low-risk, outpatient procedures is applied more selectively.
- Trial name
- NCT07036367
- Testing
- Sublingual Melatonin
- Where
- 2 sites in Egypt, Iraq
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Percutaneous Nephrolithotripsy (PCNL)
Adding Dexmedetomidine or Tramadol to Paracetamol- An Effort to Attenuate Catheter Related Bladder Discomfort
The insertion of a urinary catheter in a patient undergoing a surgical procedure, especially urinary interventions, may lead to catheter-related bladder discomfort (CRBD) with varying degrees of severity during the postoperative…
- Trial name
- NCT06274333
- Testing
- Dexmedetomidine 0.5 mic/kg, Tramadol 1mg/kg, Paracetamol 10mg/kg
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Abdominal Compartment Syndrome
Intraoperative Peak Airway Pressure Changes on Postoperative Pulmonary Function After Muscle Plication
An abdominal panniculus excision procedure is known as an abdominoplasty (panniculectomy). Musculofascial plication is a crucial aspect of abdominoplasty, especially for patients with significant divarication of the recti…
- Trial name
- NCT06291389
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Al-Azhar University
Preoperative Anxiety
Comparing Two Doses of Oral Melatonin as Premedication in Children Undergoing Surgery
Preoperative anxiety is a common issue in pediatric anesthesia. Children often experience anxiety and uneasiness due to uncertain outcomes.
- Trial name
- NCT06489327
- Testing
- melatonin (Circadin ®) 0.2 mg/kg, melatonin (Circadin ®) 0.4 mg/kg
- Where
- 2 sites in Egypt, Iraq
- Volunteers
- 120 people
- Sponsor
- Al-Azhar University
Rhinitis
Nasal Packing Duration and Development of Pharyngitis After Septorhinoplasty Surgery
Septoplasty or septal reconstruction is a corrective surgical procedure performed to straighten the nasal septum. It may be associated with numerous complications.
- Trial name
- NCT06291402
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Al-Azhar University
Vitiligo, Topical Fluorouracil
Topical 5-Fluorouracil Effervescent Powder in the Treatment of Vitiligo
A novel approach for 5-Fluorouracil delivery based on a solid effervescent formulation is proposed . 5-Fluorouracil is water soluble (~50mg/ml) and therefore has been used for the development of novel topical formulations…
- Conditions
- Vitiligo, Topical Fluorouracil, Effervescent Mixture
- Trial name
- NCT05536856
- Testing
- a new effervescent mixture 5-florouracil formula, 5-Fluorouracil plain powder
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Forearm Surgery, US-Guided Supraclavicular Block
Analgesic Effect of Supraclavicular Block and Interscalene Analgesia Versus an Intercostobrachial Nerve Block Versus PCA in Forearm Surgery
The etiology of tourniquet pain is complex, and the study team hypothesizes that blocking with Interscalene brachial plexus block (ISBPB) is more efficient in decreasing the incidence of tourniquet pain in comparison with other…
- Conditions
- Forearm Surgery, US-Guided Supraclavicular Block, Interscalene Analgesia, Tourniquet Pain
- Trial name
- NCT05602636
- Testing
- bupivacaine, midazolam
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Cesarean Section, Ultrasound Guided Transversus Abdominis Plane Block
Ultrasound Guided TAPB vs Surgical TAPB With Bupivacaine in Cesarean Section
The aim of this study is to compare Surgical Transversus abdominis plane block and Ultrasound guided transversus abdominis plane block (TAPB) as a postoperative analgesic regimen in female patients undergoing elective cesarean…
- Conditions
- Cesarean Section, Ultrasound Guided Transversus Abdominis Plane Block, Surgical Transversus Abdominis Plane Block, Bupivacaine
- Trial name
- NCT05750992
- Testing
- surgical TAP block, US guided TAP block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Al-Azhar University
Periodontitis Stage II
Melatonin Loaded in Injectable Platelet-Rich Fibrin in the Management Periodontitis
melatonin loaded in injectible platelet rich fibrin in treatment of periodontitis
- Trial name
- NCT07316582
- Testing
- Melatonin-Loaded Injectable Platelet-Rich Fibrin, injectible platelet rich fibrin (i-PRF )
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Rheumatoid Arthritis
The Effect of Cilostazol on Rheumatoid Arthritis Patients
The goal of this study is to evaluate the effect of cilostazol on Rheumatoid Arthritis patients. It aims to answer the questions of : 1.
- Trial name
- NCT05671497
- Testing
- Cilostazol 100 MG, conventional synthetic antirheumatic drugs
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Lichen Planus, Oral
The Efficacy of Selenium as an Alternative or Complementary Topical Treatment of Oral Lichen Planus
evaluate clinically and biochemically the efficacy of topically applied selenium as complementary or alternative to triamcinolone acetonide 0.1% and tacrolimus 0.1% in patients with oral lichen planus.
- Trial name
- RCT (NCT06362005)
- Testing
- Triamcinolone Acetonide 0.1% Oint, Tacrollimus Topical, Selenium
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Al-Azhar University
Chronic Low Back Pain
Pain Neuroscience Education Combined With Lumbar Stabilization Exercises on Disability and Kinesiophobia Among Patients With Chronic Low Back Pain
This study will investigate the effect of adding Pain Neuroscience Education (PNE) to a standard lumbar stabilization exercise program on disability and kinesiophobia among patients with chronic low back pain in the Gaza Strip.
- Trial name
- NCT07307859
- Testing
- Experimental Group - Lumbar Stabilization Exercises + PNE, Control Group - Lumbar Stabilization Exercises Only
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Esthetic Zone
Efficacy of i-PRF Usage in Vestibular Socket Therapy
This study aims for evaluation of A novel method for evaluating i-PRF usage in vestibular socket therapy for immediate implant in defective fresh extraction site.
- Trial name
- NCT07304986
- Testing
- Immediate implant with VST, Immediate implant with VST and i-prf
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Pulmonary Atelectasis, Postoperative
Ultrasound Evaluation of Preventive Measures for Postoperative Lung Atelectasis After Surgery
the aim of this prospective randomized blinded clinical study will be to assess the ultrasound evaluation of different preventive measures of post operative lung atelectasis in abdominal surgeries; these measures include…
- Trial name
- LUS/PEEP/RM (NCT06654778)
- Testing
- PEEP, PEEP/RM, PEEP/RM/RF
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Malocclusion, Class I/II, Crowding
A Comparative Study Between Modified Miniscrew-Assisted Rapid Palatal Expander And Modified Rapid Palatal Expander in Molar Distalization Using Cone- Beam Computed Tomography
Comparative study between modified miniscrew-assisted rapid palatal expander and modified rapid palatal expander in molar distalization using CBCT.
- Conditions
- Malocclusion, Class I/II, Crowding, Maxillary First Molar Distalization
- Trial name
- MIDPAC (NCT07038902)
- Testing
- Group A: Modified Miniscrew-Assisted Rapid Palatal Expander (MARPE), Group B: Modified Rapid Palatal Expander (RPE)
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University