Clinical trials: sponsored by Shirley Ryan AbilityLab
Traumatic Brain Injury, Anxiety
Sleep Quality, Heart Rate Variability and Anxiety Following Brain Injury
The investigators predict that decreased heart rate variability and poor sleep quality will be significantly correlated with higher self-reported anxiety following brain injury.
- Trial name
- NCT04652895
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke, Chronic Stroke
Safety and Efficacy of Samsung GEMS-H Device Training in Sub-Acute and Chronic Stroke
A single-site, interventional, single-arm trial to evaluate the safety and efficacy on functional mobility following Samsung GEMS-H (Gait Enhancing and Motivating System - Hip) device training in participants with sub-acute and…
- Trial name
- NCT04285060
- Testing
- Samsung GEMS-H
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Samsung Electronics
Speech and Language Disorder, Cerebral Palsy
Effect of mCIMT Casting on Speech-language Outcomes in Children With Hemiparesis
Modified constraint-induced movement therapy (mCIMT) has been successfully used with children who have hemiplegia (weakness or paralysis on one side of the body.) mCIMT uses a removable cast during treatment and home exercise…
- Conditions
- Speech and Language Disorder, Cerebral Palsy, Hemiplegia, Hemiparesis
- Trial name
- NCT04259814
- Testing
- Speech-language therapy (SLT), Modified constraint-induced movement therapy (mCIMT)
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Shirley Ryan AbilityLab
Acute Stroke, Cervical Spinal Cord Injury
Motor Recovery Training for Hand and Digits in Stroke and SCI
This study will use evaluate a hand therapy device training isolated finger control with engaging video gaming technology to facilitate hand and digit recovery in patients with acute stroke and cervical spinal cord injury.
- Trial name
- NCT04688229
- Testing
- Hummingbird hand training device plus standard of care rehabilitation
- Volunteers
- 24 people
- Sponsor
- Shirley Ryan AbilityLab
Occupational Therapy, Epidemiology
Interactive Self-Management Augmented by Rehabilitation Technologies
Background: Stroke is a leading cause of long-term disability in the US. Mild stroke comprises half of stroke hospital admissions, but most people with mild stroke receive no rehabilitation services.
- Conditions
- Occupational Therapy, Epidemiology, Neurologic Disorder
- Trial name
- iSMART (NCT04743037)
- Testing
- iSMART
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Washington University School of Medicine
Spinal Cord Injury
Lower Limb Function After Spinal Cord Injury
This is a randomized, experimental study that examines the physiology of central nervous system pathways contributing to the control of bilateral movements in individuals with spinal cord injuries and promotes the recovery of…
- Trial name
- NCT02635893
- Testing
- D-Cycloserine, Training, Stimulation
- Where
- United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Stroke
Deficit Fields for Stroke Recovery
This study investigates the potential of customized robotic and visual feedback interaction to improve recovery of movements in stroke survivors.
- Trial name
- NCT02570256
- Testing
- Deficit-fields to reduce error, Deficit-fields to expand range of motion, Deficit-fields to improve function
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Stroke
In Home VR Therapy
Virtual reality is a video game in which a person and their real-time movements are represented on a screen in a virtual environment.
- Trial name
- NCT03062345
- Testing
- Single-User Virtual Reality Upper Extremity Therapy, Multi-User Virtual Reality Upper Extremity Therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injury
Neuroplasticity After Spinal Cord Injury
The long-term goal is to acquire scientific knowledge that can be used to develop mechanistic-driven intervention strategies aiming at restoring upper and lower-limb motor function in individuals with cervical or thoracic spinal…
- Trial name
- NCT02446210
- Testing
- Magstim 200, Digitimer electrical stimulator
- Where
- United States
- Volunteers
- 514 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injuries
Vibration for Muscle Spasms After Spinal Cord Injury
This study uses closed-loop control of tendon vibration to implement clinically meaningful management of muscle spasms after spinal cord injury (SCI), and to understand the mechanisms responsible for spasm generation change in…
- Trial name
- NCT03598504
- Testing
- Wearable EMG/Vibration device
- Where
- United States
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Amputation; Traumatic, Hand, and Wrist, Amputation; Traumatic, Hand, at Wrist Level
Application of Targeted Reinnervation for People With Transradial Amputation
The purpose of this study is to improve prosthesis control for transradial amputees with combining targeted muscle reinnervation surgery (TMR) and pattern recognition control.
- Trial name
- NCT02349035
- Testing
- Compare control of multifunction transradial prosthesis, Perform TMR surgery and evaluate transradial TMR pattern recognition control of multifunctional prostheses.
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injury
Sympathetic-Somatomotor Coupling in Human Spinal Cord Injury
Significance: The long term objective of this study is to improve physical therapy and fitness programs in people with spinal cord injury.
- Trial name
- NCT02115685
- Testing
- Treadmill Training
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Aphasia
Web-Based Treatment for Aphasia
This prospective randomized clinical trial implements an innovative broadband web-based treatment program for individuals with chronic aphasia, and evaluates its efficacy.
- Trial name
- Web-ORLA (NCT04413136)
- Testing
- Web-ORLA, Control
- Volunteers
- 35 people
- Sponsor
- Shirley Ryan AbilityLab
Cerebral Vascular Accident
Implementing a CO-OP Group in the Day Rehab Setting: A Pilot Study.
This is pilot study will examine the effectiveness of a group curriculum developed from the CO-OP approach. This study has two aims, the first is to standardize the group curriculum and the second is to compare the data from the…
- Trial name
- NCT04246385
- Testing
- CO-OP Group
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Shirley Ryan AbilityLab
Disabled Persons
Our Peers - Empowerment and Navigational Support
People with physical disabilities experience well documented barriers to healthcare access, quality and outcomes. The purpose of this study is to implement and evaluate a 12-month peer health navigator intervention (called Our…
- Trial name
- OP-ENS (NCT04784611)
- Testing
- Our Peers - Empowerment and Navigational Support (OP-ENS) Peer Health Navigator Intervention
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- University of Illinois Chicago
Knee Osteoarthritis
Positive Pressure Treadmill Walking for Individuals With Knee Pathology
Our goal is to compare the serum biomarker changes of joint disease that occur in response to partially off-loaded (50%) walking exercise to regular (100%) walking exercise while on a Lower Body Positive Pressure (LBPP)…
- Trial name
- LBPPKNEEOA (NCT04747444)
- Testing
- Anti-Gravity Treadmill
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injury Cervical, Stroke
BoMI for Muscle Control
People with spinal cord injury (SCI), stroke and other neurodegenerative disorders can follow two pathways for regaining independence and quality of life. One is through clinical interventions, including therapeutic exercises.
- Trial name
- NCT04641793
- Testing
- Motion and Emg Control
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Post-stroke Shoulder Pain and Spasticity
Randomized DB Controlled Trial of Botulinum Toxin A in Hemiplegic Shoulder Pain and Spasticity
The purpose of this study is to evaluate whether botulinum toxin type A injected into muscles around the shoulder is effective in treating shoulder pain and improving function in patients with shoulder pain and involuntary muscle…
- Trial name
- NCT00661089
- Testing
- Botulinum Toxin Type A - OnabotulinumtoxinA
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Shirley Ryan AbilityLab
Amputation
Adaptive Recalibration of Prosthetic Leg Neural Control System
The purpose of this study is for transfemoral amputees to walk with an experimental robotic prosthesis. Electric signals will be measured from their muscles and used to help control an artificial leg.
- Trial name
- NCT02355912
- Testing
- Powered knee and ankle prosthesis
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Parkinson's Disease
Cycling in Parkinson's Disease
The purpose of this study is to assess the effectiveness of a forced exercise aerobic exercise program, utilizing a cycling activity, on specific gait parameters and balance in individuals with Parkinson's Disease (PD).
- Trial name
- NCT02175082
- Testing
- Cycling at Forced rate, Cycling at self-selected rate
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Shirley Ryan AbilityLab