Clinical trials: sponsored by Capital Medical University
Mild Cognitive Impairment
Effect of Vitamin D and Folic Acid on Mild Cognitive Impairment
The purpose of this study is to investigate the effects of Vitamin D3 combined with Folic Acid on mild cognitive impairment (MCI).
- Trial name
- NCT07486141
- Testing
- Vitamin D3 (800 IU/d) and Folic Acid(0.4mg/d), Vitamin D3 (1600 IU/d) and Folic Acid(0.4mg/d)
- Where
- China
- Volunteers
- 380 people
- Sponsor
- Capital Medical University
Stroke Patients, Tracheostomy
A Speaking-Valve-Based Decannulation Protocol for Tracheostomized Stroke Patients
To evaluate the feasibility of a speaking-valve-based decannulation protocol in tracheostomized stroke patients
- Trial name
- SVBDP-TSP (NCT07904169)
- Testing
- Decannulation Protocol
- Volunteers
- 207 people
- Sponsor
- Hongying Jiang, MD
Acute Ischemic Stroke
Albumin for Patients With Acute Large Vessel Occlusive Stroke Undergoing Endovascular Therapy -2
This study is a prospective, multicenter, open-label, randomized controlled clinical trial. The investigators will apply albumin to the reperfusion treatment of patients with acute ischemic stroke in the anterior circulation.
- Trial name
- ARISE-2 (NCT07263308)
- Testing
- Albumin, Endovascular treatment
- Where
- 61 sites in China
- Volunteers
- 1,192 people
- Sponsor
- Capital Medical University
Prolonged Disorders of Consciousness, Tracheostomy
A Speaking-Valve-Based Decannulation Protoco for Patients With a Prolonged Disorders of Consciousness
To evaluate the feasibility of a standardized tracheostomy decannulation protocol for patients with prolonged Disorders of Consciousness (pDoC) .
- Trial name
- STEP-DoC (NCT07183670)
- Testing
- decannulation protocol
- Where
- 2 sites in China
- Volunteers
- 184 people
- Sponsor
- Hongying Jiang, MD
Laryngotracheal Lesions, Tracheostomy Complications
Laryngotracheal Lesions in Adults With Long-Term Tracheostomy
This multicenter prospective observational cohort study will enroll 224 adults with a tracheostomy tube in place for at least 14 days.
- Conditions
- Laryngotracheal Lesions, Tracheostomy Complications, Tracheal Stenosis, Tracheomalacia
- Trial name
- NCT07901946
- Testing
- Standardized Three-Station Bronchoscopy
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Hongying Jiang, MD
Spinal Cord Injury
Recovery and Safety After Epidural Spinal Cord Stimulation in People With Spinal Cord Injury
Spinal cord injury can cause lasting difficulties with movement, sensation, bladder and bowel function, and daily activities. Epidural spinal cord stimulation delivers electrical pulses through implanted electrodes and may be…
- Trial name
- NCT07900490
- Testing
- Epidural Spinal Cord Stimulation
- Where
- China
- Volunteers
- 6 people
- Sponsor
- Hainan University
Adverse Drug Reaction, Cinepazide
Post-Marketing Surveillance of the Cinepazide Maleate Injection: a Real World Study
Cinepazide Maleate Injection is widely used in cerebrovascular disease in china. The safety of the cinepazide, especially the blood system, has not been fully evaluated in Chinese population.
- Conditions
- Adverse Drug Reaction, Cinepazide, Stroke
- Trial name
- PACER (NCT01946919)
- Where
- 61 sites in China
- Volunteers
- 18,260 people
- Sponsor
- Peking University Third Hospital
Pregnancy, Dietary Inflammatory Index (DII)
Pregnancy Anti-inflammatory Diet Intervention Study
Dietary patterns may influence maternal inflammatory status and pregnancy outcomes. However, structured anti-inflammatory dietary interventions specifically designed for pregnant women remain limited.
- Trial name
- PAID2026 (NCT07890441)
- Testing
- Anti-inflammatory Dietary Intervention
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Influenza, Human
Evaluation of the Efficacy and Safety of 102D-6 in the Treatment of Acute Uncomplicated Influenza
The goal of this Phase II/III study is to investigate the safty and efficacy of 102D-6 in adolescents and adults with influenza. The main aim to answer: 1.
- Trial name
- NCT07893847
- Testing
- 20 mg 102D-6 dry suspension, 40 mg 102D-6 dry suspension
- Where
- China
- Volunteers
- 570 people
- Sponsor
- Capital Medical University
Chronic Insomnia
Shiwei Anshen Granules for Chronic Insomnia
This is a multi-center, randomized, controlled clinical study inlcuding 240 subjects with chronic insomnia. The purpose of this study is to evaluate the efficacy and safety of Shiwei Anshen Granules (an Chinese herbal…
- Trial name
- Shiwei-Anshen (NCT07895329)
- Testing
- Shiwei Anshen granules
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Dongzhimen Hospital, Beijing
Respiratory Viral Infections, Influenza
Effect of MxA Guidance on Antiviral Treatment in Respiratory Viral Infections
The goal of this clinical trial is to evaluate the effects of myxovirus resistance protein A (MxA)-guided antiviral treatment on treatment duration and adverse outcomes in adults hospitalized with influenza or COVID-19, compared…
- Conditions
- Respiratory Viral Infections, Influenza, SARS CoV 2 Infection
- Trial name
- NCT07892872
- Testing
- Baseline MxA testing, Serial MxA testing, MxA result feedback and antiviral treatment recommendations
- Where
- China
- Volunteers
- 618 people
- Sponsor
- Capital Medical University
Mechanical Ventilation
Titration of PS Guided by FI : A Pilot Study
The goal of this single-center, pilot, randomized controlled trial is to evaluate the feasibility and preliminary efficacy of using the Flow Index (FI) to guide Pressure Support (PS) titration in adult patients receiving Pressure…
- Trial name
- NCT07769307
- Testing
- FI-guided ventilator support adjustment, Conventional PS titration
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Capital Medical University
Critical Illness
Multidimensional Dysfunction in Patients With Chronic Critical Illness in China
Over the past two decades, rapid advances in critical care medicine have markedly reduced short-term mortality among critically ill patients.
- Trial name
- NCT07585578
- Testing
- Data Collection and Assessment
- Where
- 4 sites in China
- Volunteers
- 888 people
- Sponsor
- Hongying Jiang, MD
Constipation
Oat Milk for Laxation
This study intends to recruit 90-100 constipated participants aged 25-50 years, including an equal number of males and females, from the faculty and logistics staff of Capital Medical University.
- Trial name
- NCT07302542
- Testing
- oat milk
- Where
- China
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Mechanical Ventilation, Critical Care
Computed Inspiratory Muscle Pressure to Monitor Inspiratory Effort During Pressure-Targeted Assist/Control Ventilation
The goal of this study is to validate computed inspiratory muscle pressure (cPmus) for monitoring inspiratory effort in adults receiving pressure-targeted assist/control ventilation (P-A/C) who retain spontaneous breathing.
- Trial name
- NCT07886918
- Testing
- Positive end-expiratory pressure 11, Positive end-expiratory pressure 9, Positive end-expiratory pressure 7
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Jian-Xin Zhou
Unruptured Intracranial Aneurysms, Pituitary Neuroendocrine Tumor
China Treatment Trial for Tumor in Sellar Region With Unruptured Intracranial Aneurysm
The goal of this observational study is to learn about the treatment strategies for tumor in sellar region with unruptured intracranial aneurysms in the Chinese population.
- Conditions
- Unruptured Intracranial Aneurysms, Pituitary Neuroendocrine Tumor, Craniopharyngioma, Meningioma
- Trial name
- ChTTSRUIA (NCT07809178)
- Testing
- Tumor resection followed by aneurysm treatment, Aneurysm treatment followed by tumor resection, Observation
- Where
- China
- Volunteers
- 608 people
- Sponsor
- Cheng sen
Meningioma, CDK4/6 Inhibitor
IN10018 in Combination With Dalpiciclib for Progressive Meningiomas
This open-label Phase Ib study will evaluate the safety, tolerability, and preliminary effectiveness of IN10018 in combination with dalpiciclib in adults with progressive meningiomas.
- Trial name
- NCT07652762
- Testing
- Ifebemtinib, Dalpiciclib
- Where
- 2 sites in China
- Volunteers
- 24 people
- Sponsor
- Capital Medical University
Acute Ischemic Stroke
Ischemic Post-conditioning in Acute Ischemic Stroke Thrombectomy (PROTECT-2)
Ischemic post-conditioning is a neuroprotective strategy that has been proven to attenuate reperfusion injury in animal models of stroke.
- Trial name
- NCT05789823
- Testing
- Mechanical thrombectomy combined with ischemic post-conditioning, Mechanical thrombectomy alone
- Where
- 6 sites in China
- Volunteers
- 160 people
- Sponsor
- Capital Medical University
Mechanical Ventilation, Critical Care
Computed Inspiratory Muscle Pressure to Monitor Inspiratory Effort During Pressure Support Ventilation
The goal of this study is to validate computed inspiratory muscle pressure (cPmus) for monitoring inspiratory effort in adults receiving pressure support ventilation.
- Trial name
- NCT07886892
- Testing
- Pressure support 15, Pressure support 13, Pressure support 11
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Jian-Xin Zhou
Sarcopenia, Breast Cancer
Exercise Intervention for Breast Cancer Patients With Sarcopenia
Sarcopenia is a common yet underrecognized complication in breast cancer survivors during rehabilitation, characterized by loss of muscle mass, reduced muscle strength, and impaired physical function, which adversely affects…
- Trial name
- EX-BCSarc (NCT07732101)
- Testing
- "Exercise for Muscle Health" Program
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Capital Medical University