Clinical trials: sponsored by Göteborg University
Pulmonary Embolism Acute
Reduced-Dose Versus Full-Dose Alteplase for High-Risk Pulmonary Embolism
High-risk pulmonary embolism is a life-threatening condition requiring immediate reperfusion therapy. Full-dose systemic thrombolysis is recommended as first-line treatment, but its use is limited by the risk of major bleeding…
- Trial name
- REDSTEM (NCT07816978)
- Testing
- Reduced-dose alteplase, Full-dose alteplase
- Where
- 23 sites in Denmark, Norway and 1 more
- Volunteers
- 400 people
- Sponsor
- Sahlgrenska University Hospital
Paraesophageal Hernia
Gastropexy in the Repair of Patients With Paraesophageal Hernias
Patients scheduled for surgery for primary paraesophageal herniation are randomized to either conventional surgical hernia repair or with the addition of gastropexy.
- Trial name
- PEH3 (NCT06107634)
- Testing
- Gastropexy, Paraesophageal hernia repair
- Where
- 6 sites in Sweden
- Volunteers
- 150 people
- Sponsor
- Ersta Diakoni
Rheumatoid Arthritis (RA)
Nutrition in Rheumatoid Arthritis
Background: Individuals with Rheumatoid Arthritis (RA) often experience persistent symptoms such as pain and stiffness despite modern pharmacological treatments. They also have an increased risk of cardiovascular disease.
- Trial name
- NUTRA (NCT06831331)
- Testing
- Healthy diet based on NNR2023, Control/waiting-list
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Vastra Gotaland Region
Coronary Artery Disease, Arterial Stiffness, Blood Pressure
Expanded Studies on the SCAPIS Stockholm Reexamination Cohort
The Swedish CArdioPulmonary bioImage Study (SCAPIS) is a unique, large-scale national research initiative involving 30,000 randomly selected individuals aged 50-64, recruited between 2014 and 2018.
- Conditions
- Coronary Artery Disease, Arterial Stiffness, Blood Pressure, AORTIC VALVE DISEASES, Mitral Valve Stenosis and/or Insufficiency
- Trial name
- SCAPIS-ReEx (NCT07476703)
- Testing
- Coronary computer tomography (CCTA), Echocardiograhy and aortic ultrasound, Liver elastography
- Where
- Sweden
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Danderyd Hospital
Critical Illness, Ethics
Life Sustaining Treatments in Critically Ill Children
Summary of the Research on Withdrawing and Withholding Life-Sustaining Treatment for Critically Ill Children Background Medical treatments require regular evaluation to ensure they align with the patient's best interests…
- Conditions
- Critical Illness, Ethics, End of Life Care
- Trial name
- LST-Ped-Int (NCT07401420)
- Testing
- There is no intervention
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Göteborg University
Pediatric Disorder, Critical Illness
Attitudes to Decisions to Withdraw or Withhold Life-sustaining Treatments in Critically Ill Children
The aim of this study is to investigate attitudes on decisions to withdraw or withhold life-sustaining treatments in critically ill children in Swedish intensive care units.
- Conditions
- Pediatric Disorder, Critical Illness, Ethics, Narrative
- Trial name
- LSTPedSurvey (NCT06281743)
- Testing
- Survey
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Göteborg University
Ischemia, Cerebral, Ischemic Stroke
Detection of Cerebral Ischemia With Artificial Intelligence.
In patients undergoing planned surgery for carotid tromendarterendectomy, a non-invasive device that registers heart rate variability is attached.
- Conditions
- Ischemia, Cerebral, Ischemic Stroke, Artery Occlusion, Artery Carotid Stenosi
- Trial name
- CIDAI-BAS (NCT03919370)
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Linda Block
Parkinson Disease, Stroke
COMPuter-assisted Self-training to Improve EXecutive Function
This project explores the effects of specialized computer-based cognitive rehabilitation (CBCR) targeting executive functions in three groups of patients: Stroke, Cardiac Arrest and Parkinson's Disease.
- Conditions
- Parkinson Disease, Stroke, Cardiac Arrest, Cognitive Dysfunction
- Trial name
- COMPEX (NCT04229056)
- Testing
- Computer-based cognitive rehabilitation (CBCR), General computer-based cognitive stimulation
- Where
- 2 sites in Denmark
- Volunteers
- 307 people
- Sponsor
- Bispebjerg Hospital
Depression Mild, Depression Moderate
iCBT for Seniors With Depression in Primary Care
This clinical trial aims to evaluate the potential benefits of internet cognitive behavioural therapy (iCBT) for elderly patients with mild/moderate depression and compare its effectiveness with the current treatment as usual…
- Trial name
- NCT06537869
- Testing
- iCBT for depression
- Where
- Sweden
- Volunteers
- 390 people
- Sponsor
- Göteborg University
Asthma in Children, Transplantation
Digital Delivery of Person-centered Transitional Care
Advances in medical care have extended the life expectancy of individuals with congenital and pediatric-onset diseases, leading to an increased need for effective transition programs as these individuals move from pediatric to…
- Trial name
- DigiStep (NCT06823622)
- Testing
- Stepstones transition program
- Where
- 2 sites in Sweden
- Volunteers
- 100 people
- Sponsor
- Göteborg University
Bipolar Depression
OSU6162 in Bipolar Depression (OBID)
An explorative, open label, single armed, flexible dose, single center, phase IIa study of 8 weeks, initiated in subjects with bipolar depression. The study will consist of 9 visits and 1 safety visit.
- Trial name
- OBID (NCT05296356)
- Testing
- OSU6162
- Where
- Sweden
- Volunteers
- 22 people
- Sponsor
- Göteborg University
Depression, Depressive Disorder, Treatment-Resistant
OSU6162 as add-on in SSRI/SNRI-resistant Depression
This is a randomised, placebo-controlled, parallel-group trial comparing OSU6162 at flexible dosage with placebo as add-on to treatment with an SSRI/SNRI in patients with depression that have not responded to treatment with an…
- Conditions
- Depression, Depressive Disorder, Treatment-Resistant, Depressive Disorder, Depressive Episode
- Trial name
- ODEN (NCT05641623)
- Testing
- OSU6162
- Where
- 4 sites in Sweden
- Volunteers
- 180 people
- Sponsor
- Göteborg University
Urinary Incontinence (UI)
HIFEM for Incontinence After Menopause High-Intensity Focused Electromagnetic (HIFEM)
It is not difficult to imagine that leaking urine affects life in many contexts. Unfortunately, it is everyday life for far too many people in our society.
- Trial name
- HIM2025 (NCT07260604)
- Testing
- Pelvic floor training as described in point a above, with the addition of HIFEM., Pelvic Floor exercises
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Göteborg University
Peri-Implantitis
Peri-implantitis - Reconstructive Surgical Therapy
The project will evaluate the potential benefit of the use of bone replacement graft as an adjunct to surgical therapy of peri-implantitis.
- Trial name
- NCT03077061
- Testing
- Open flap debridement, Bone replacement graft
- Where
- Sweden
- Volunteers
- 140 people
- Sponsor
- Göteborg University
Nociceptive Pain
Comparison of Different Objective Nociceptive Measurement Methods During Surgery
Traditionally, hemodynamic response e.g. pulse and blood pressure are used to evaluate pain in humans who are anesthetized. These values, however, can be affected by factors other than pain response .
- Trial name
- NCT05218551
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Göteborg University
Ectopic Tooth Eruption, Palatal Expansion Technique
The Effectiveness of Early Intervention to Correct the Position of PDC:s
Approximately 2-3% of children will have problems with one or both of their permanent or 'adult' canine teeth in the upper jaw. These canine teeth sometimes fail to erupt properly, because they are displaced into the roof of the…
- Conditions
- Ectopic Tooth Eruption, Palatal Expansion Technique, Randomized Clinical Trial
- Trial name
- PDC (NCT06267989)
- Testing
- Extraction of the primary canine teeth, Expansion
- Where
- 3 sites in Germany, Sweden and 1 more
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Acute Postoperative Pain in Urological Surgery, Pain Management in Postoperative Care (Including Opioid-Sparing Approaches)
Nudging to Promote the Use of Transcutaneous Electrical Nerve Stimulation for Postoperative Pain Relief
This study aims to increase the use of transcutaneous electrical nerve stimulation (TENS) for acute postoperative pain relief. TENS, a non-pharmacological treatment using electrical impulses, can enhance pain relief, reduce…
- Trial name
- Nudging pain (NCT06696430)
- Testing
- Educational Intervention on TENS Usage, Nudging Intervention to Promote TENS Usage
- Where
- 3 sites in Sweden
- Volunteers
- 500 people
- Sponsor
- Pether Jildenstal
Peri-Implantitis
Air-polishing in the Treatment of Peri-implantitis
The aim of the present study is to evaluate the potential benefit of the adjunctive use of an air-polishing device in the non-surgical treatment of peri-implantitis as compared to mechanical infection control alone.
- Trial name
- NCT04847648
- Testing
- Air-polishing, Mechanical decontamination
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Göteborg University
Childhood Cancer, Communication
Pictorial Support in Person-centred Care for Children (PicPecc)
Introduction: Person-centred care is based on the assumption that every person has resources that should be used in the care situation.
- Conditions
- Childhood Cancer, Communication, Symptoms and Signs
- Trial name
- PicPecc (NCT04433650)
- Testing
- Pictorial support in person-centred care for children (PicPecc)
- Where
- Sweden
- Volunteers
- 29 people
- Sponsor
- Göteborg University
Lifestyle-related Condition
Prevention of Lifestyle-related Disorders Based on Functional Examinations
The goal of this randomised controlled trial is to examine the effects of functional examinations and feedback/support on healthy 40-year-olds.
- Trial name
- PREVFUNKTION (NCT06309342)
- Testing
- PREVFUNKTION, Control
- Where
- 2 sites in Sweden
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Lena Bornhoft