Clinical trials: sponsored by Peking University Third Hospital
IVF Outcome
Trigger Timing in Ovarian Stimulations
The gonadotrophin-releasing hormone (GnRH) antagonist protocol is widely used in in vitro fertilisation (IVF) for its flexibility and ability to reduce the risk of ovarian hyperstimulation syndrome (OHSS).
- Trial name
- NCT04163133
- Testing
- 1-2 days later trigger than regular timing
- Where
- China
- Volunteers
- 834 people
- Sponsor
- Peking University Third Hospital
Periarticular Bone Defect, Proximal Humerus Fracture
Magnesium Alloy Scaffold With Controlled Degradation for Periarticular Bone Defects
This prospective, multi-center, randomized controlled clinical trial is designed to evaluate the effectiveness and safety of a biodegradable magnesium alloy scaffold with controlled degradation for the treatment of periarticular…
- Conditions
- Periarticular Bone Defect, Proximal Humerus Fracture, Distal Radius Fracture, Tibial Plateau Fracture
- Trial name
- MgScaf-PBD (NCT07906730)
- Testing
- Magnesium Alloy Scaffold, Calcium Sulfate Bone Graft Substitute
- Where
- 4 sites in China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Injuries, Recovery Quality
Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Postoperative Recovery Quality in Patients Undergoing Anterior Cruciate Ligament Reconstruction
Background: Arthroscopic anterior cruciate ligament reconstruction (ACLR) is a common orthopedic surgery. Postoperative pain, inflammatory response and opioid-related adverse events impair early recovery quality.
- Conditions
- Anterior Cruciate Ligament Injuries, Recovery Quality, Auricular Vagus Nerve Stimulation
- Trial name
- NCT07904949
- Testing
- Experimental-Active taVNS
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Peking University Third Hospital
Diminished Ovarian Reserve (DOR)
Application of Autologous Adipose Stromal Vascular Fraction in the Treatment of Diminished Ovarian Reserve
A multi-center, prospective, randomised controlled clinical trial (1:1 treatment ratio), designed to investigate the efficacy and safety of autologous SVF in improving the pregnancy outcome of infertile patients with DOR.
- Trial name
- aSVF-DOR (NCT07901218)
- Testing
- Lower abdominal liposuction and preparation of SVF, Ovarian injection, Conventional ART treatment
- Where
- 4 sites in China
- Volunteers
- 260 people
- Sponsor
- Peking University Third Hospital
Carcinoma, Renal Cell, Inferior Vena Cava Tumor Thrombus
Habitat Analysis of Tumor Thrombus for Vena Cava Wall Invasion in Renal Cell Carcinoma
Tumor thrombus in the inferior vena cava can invade the vessel wall. Doctors must know the invasion status before surgery. The status changes the surgical plan. Preoperative imaging has limited accuracy for wall invasion.
- Trial name
- HABITAT (NCT07901569)
- Where
- China
- Volunteers
- 273 people
- Sponsor
- Liu Zhuo
Adverse Drug Reaction, Cinepazide
Post-Marketing Surveillance of the Cinepazide Maleate Injection: a Real World Study
Cinepazide Maleate Injection is widely used in cerebrovascular disease in china. The safety of the cinepazide, especially the blood system, has not been fully evaluated in Chinese population.
- Conditions
- Adverse Drug Reaction, Cinepazide, Stroke
- Trial name
- PACER (NCT01946919)
- Where
- 61 sites in China
- Volunteers
- 18,260 people
- Sponsor
- Peking University Third Hospital
Obesity, Metabolic Syndrome
The Interaction and Regulation Mechanism of Different Exercise Patterns With Metabolic Syndrome and Related Metabolic Diseases
In order to obtain suitable exercise intervention model for children and adolescents with obese or metabolic syndrome in China, we conduct a RCT to examine the effects of different intensity exercise intervention on weight, and…
- Trial name
- NCT04984005
- Testing
- Low intensity exercise training, Moderate intensity exercise training, Intermittent high intensity exercise training
- Where
- China
- Volunteers
- 366 people
- Sponsor
- Peking University Third Hospital
Ankylosing Spondylitis (AS)
Ivarmacitinib With or Without Celecoxib for Ankylosing Spondylitis
Background: Ankylosing spondylitis (AS) is a chronic, progressive inflammatory disease mainly affecting the spine and sacroiliac joints, causing pain, stiffness, structural damage, and functional disability.
- Trial name
- NCT07894497
- Testing
- Ivarmacitinib with celecoxib, Ivarmacitinib Monotherapy
- Volunteers
- 138 people
- Sponsor
- Peking University Third Hospital
Unruptured Intracranial Aneurysms, Cerebrovascular Event
Efficacy and Safety of Methylprednisolone After Flow-Diverter Stent Implantation in Unruptured Intracranial Aneurysms
Study Title: Testing Methylprednisolone to Prevent Strokes After a Stent Procedure for Brain Aneurysms What is the purpose of this study? This study aims to find out if a short course of a steroid medicine called…
- Conditions
- Unruptured Intracranial Aneurysms, Cerebrovascular Event, Hemorrhagic Stroke, Methylprednisolone
- Trial name
- NCT07353749
- Testing
- Methylprednisolone (Injectable Form)
- Where
- China
- Volunteers
- 864 people
- Sponsor
- Duan Chuanzhi
Improve Facial Wrinkles
Clinical Trial Protocol for the Effectiveness and Safety of Radiofrequency Skin Therapy Equipment in Improving Facial Skin Wrinkles
Evaluate the clinical efficacy and safety of the radiofrequency skin therapy device (model specification: RFM-01) produced by ReFumei (Hunan) Technology Co., Ltd. for improving facial skin wrinkles
- Trial name
- NCT07894120
- Testing
- Radiofrequency skin therapy equipment developed and produced by ReFumei (Hunan) Technology Co., Ltd. improves facial wrinkles, The control group subjects used the radiofrequency therapy device produced by Israel Flyton Laser Co., Ltd. to improve facial wrinkles
- Where
- China
- Volunteers
- 278 people
- Sponsor
- Peking University Third Hospital
Femoroacetabular Impingement Syndrome
Comparison of Surgery With Prehabilitation, Direct Surgery and Rehabilitation for Patients With Femoroacetabular Impingement
This study aims to compare the therapeutic effects of three different treatment strategies for patients with femoroacetabular impingement.
- Trial name
- NCT07894471
- Testing
- Hip arthroscopic surgery, Standardized physical rehabilitation training
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Peking University Third Hospital
Foot Drop, Charcot-Marie-Tooth Disease Type 1A
Muscle MRI Fat Fraction Before Surgery to Predict Strength Recovery After Foot-Drop Surgery in Charcot-Marie-Tooth Disease
The purpose of this prospective observational cohort study is to determine whether the amount of fat inside the donor muscles before surgery, measured with a magnetic resonance imaging (MRI) technique called Dixon fat fraction…
- Conditions
- Foot Drop, Charcot-Marie-Tooth Disease Type 1A, Charcot-Marie-Tooth Disease Type 2A, Charcot-Marie-Tooth Disease (CMT)
- Trial name
- CMT-FF-TPT (NCT07894536)
- Testing
- Tibialis posterior tendon transfer, Individualized adjunct procedures for cavovarus deformity correction, Ankle-foot orthosis (AFO)
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Spinal Muscular Atrophy (SMA)
Effects of Different Stiffness Settings During Robotic Isokinetic Training in Children With SMA
This randomized, within-participant, contralateral-limb-controlled clinical trial will compare individually optimized compliant and rigid stiffness settings of a portable isokinetic knee training robot in children with spinal…
- Trial name
- NCT07822711
- Testing
- Portable Isokinetic Knee Training Robot With an Individually Optimized Compliant Setting, Portable Isokinetic Knee Training Robot With a Rigid Setting
- Where
- China
- Volunteers
- 13 people
- Sponsor
- Peking University Third Hospital
Spinal Epidural Hematoma
Establishment of Clinical Prediction Model for Postoperative Symptomatic Spinal Epidural Hematoma
The goal of this observational study is to establish a clinical prediction model based on artificial intelligence algorithms for patients with postoperative symptomatic spinal epidural hematoma(PSSEH) after spinal surgery.
- Trial name
- NCT06633848
- Testing
- spinal surgery
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Peking University Third Hospital
Gestational Diabetes Mellitus (GDM)
The WAIT Trial: Waiting Versus Active Induction at Term in Women With A1 Gestational Diabetes Mellitus
This multicenter, open-label, superiority randomized controlled trial will evaluate whether delaying planned induction from 40 weeks to 41 weeks improves delivery outcomes in women with A1 gestational diabetes mellitus (A1 GDM).
- Trial name
- NCT07831954
- Testing
- Timing of Planned Delivery
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Peking University Third Hospital
HFpEF - Heart Failure With Preserved Ejection Fraction
Cardiopulmonary Exercise Testing-based High-intensity Interval Training For Improving Heart Failure With Preserved Ejection Fraction
Cardiovascular-Kidney-Metabolic (CKM) Syndrome is a continuous clinical disease spectrum integrating cardiovascular, renal, and metabolic disorders.
- Trial name
- CPHIT-HFpEF (NCT07693049)
- Testing
- High-intensity interval training
- Where
- 13 sites in China
- Volunteers
- 192 people
- Sponsor
- Peking University Third Hospital
Rectal Neoplasms Malignant, Surgery
Transanal Versus Laparoscopic Total Mesorectal Excision For Rectal Cancer
Laparoscopic surgery for rectal cancer has been successfully proven to be a non-inferior alternative regarding resection quality, and oncological outcomes of patients as compared to open surgery in mangy clinical trails.
- Trial name
- NCT02966483
- Testing
- TaTME, LpTME
- Where
- 16 sites in China
- Volunteers
- 1,115 people
- Sponsor
- Sun Yat-sen University
Melanoma (Skin Cancer), Hepatocellular Carcinoma
68Ga-SorB PET/CT Imaging in Patients With Solid Tumors
This prospective, single-center, open-label exploratory diagnostic study aims to evaluate the safety, feasibility, and diagnostic performance of the novel Sortilin-targeted PET tracer 68Ga-SorB in patients with solid tumors.
- Conditions
- Melanoma (Skin Cancer), Hepatocellular Carcinoma, Lung Cancer, Breast Cancer
- Trial name
- SORB-PET (NCT07760012)
- Testing
- 68Ga-SorB PET/CT
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking University Third Hospital
Fall Risk in Middle-Aged and Older Adults
Short-term Changes in Postural Sway, Gait, and fNIRS-derived Cortical Metrics After a 4-week AI-assisted Exercise Program: a Single-arm Pre-post Study
This single-arm pre-post study will enroll 50 participants aged 52-65 years who will undergo a 4-week AI-assisted exercise intervention.
- Trial name
- NCT07876011
- Testing
- AI-assited exercise
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Benign Prostatic Hyperplasia
A Smart Wearable Device for Monitoring Urination Function in Benign Prostatic Hyperplasia
Benign Prostatic Hyperplasia (BPH) is a common condition that can cause bothersome urination problems and reduce quality of life.
- Trial name
- NCT07357012
- Testing
- Electrical Impedance Tomography (EIT) Wearable Monitoring Device
- Where
- 2 sites in China
- Volunteers
- 40 people
- Sponsor
- Peking University Third Hospital
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