Clinical trials: sponsored by Seoul National University Hospital
Constipation, Abdominal Pain
Effects of a Prebiotic-Probiotic Combination on Constipation Symptoms and Quality of Life
This study aims to evaluate whether a combination of a prebiotic (1-kestose) and a probiotic (Lacticaseibacillus rhamnosus BBH112) improves gastrointestinal symptoms and quality of life in adults with constipation-related…
- Conditions
- Constipation, Abdominal Pain, Abdominal Bloating, Abdominal Discomfort
- Trial name
- NCT07923279
- Testing
- Lacticaseibacillus rhamnosus BBH112, 1-Kestose (GF2)
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Shoulder Arthroscopy
Comparison of Postoperative Quality of Recovery by Anesthetic Method in Patients Undergoing Shoulder Arthroscopy
The aim of this study is to compare the quality of recovery in patients undergoing arthroscopic shoulder surgery depending on the type of anesthesia used: 1.
- Trial name
- NCT06638112
- Testing
- Brachial Plexus Block, General Anesthesia (control group)
- Where
- South Korea
- Volunteers
- 140 people
- Sponsor
- Seoul National University Hospital
Chronic Hepatitis b
Effectiveness of TAF in Reducing Clinical Events in CHB Patients Beyond Treatment Indications by Current Guidelines
Treatment with Tenofovir Alafenamide(TAF) in Chronic Hepatitis B (CHB) patients classified as beyond treatment indication of current international guidelines (e.g.
- Trial name
- ATTENTION (NCT03753074)
- Testing
- Tenofovir Alafenamide
- Where
- 10 sites in South Korea
- Volunteers
- 780 people
- Sponsor
- Young-Suk Lim
Hip Arthroplasty, Spinal Anesthesia
Patient-controlled Remimazolam Sedation Under Spinal Anesthesia
The goal of this clinical trial is to compare the efficacy of patient-controlled sedation (PCS) versus clinician-controlled sedation (CCS) using remimazolam in adult patients undergoing primary hip arthroplasty under spinal…
- Conditions
- Hip Arthroplasty, Spinal Anesthesia, Remimazolam, Patient-controlled Sedation
- Trial name
- NCT07661810
- Testing
- Patient-controlled sedation, Clinician-controlled sedation
- Where
- South Korea
- Volunteers
- 104 people
- Sponsor
- Seoul National University Hospital
Cardiovascular Diseases
Usefulness of Cardiovascular Disease (CVD) Management Solution
We previously developed the smartphone app (Heart4U) which is coupled with electronic medical record system in Seoul National University Bundang Hospital.
- Trial name
- NCT03392259
- Testing
- Smartphone app
- Where
- 2 sites in South Korea
- Volunteers
- 666 people
- Sponsor
- Seoul National University Hospital
Hypertensive Disorder of Pregnancy, Preeclampsia
mHealth for Hypertensive Disorder of Pregnancy
Objectives: We have developed a cardiovascular disease management application named Heart4U, with the capability of integrating with the Electronic Medical Records (EMR) system within the hospital.
- Trial name
- NCT05995106
- Testing
- Heart4U
- Where
- South Korea
- Volunteers
- 89 people
- Sponsor
- Seoul National University Hospital
Preeclampsia and Eclampsia, Stiffness, Aortic
Comparison of Longitudinal Blood Pressure and Arterial Stiffness in Preeclamptic Women After Delivery
The investigator measured the arterial stiffness using cardio-ankle vascular index (CAVI) test in patient with preeclampsia and normal pregnant women to evaluate the longitudinal change of CAVI and their predictors.
- Conditions
- Preeclampsia and Eclampsia, Stiffness, Aortic, Blood Pressure
- Trial name
- NCT04142268
- Where
- South Korea
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Cardiovascular Physiological Phenomena
Cardiac Auscultation Using Smartphones
The investigators performed a proof-of-concept study enrolling subjects with normal and pathologic heart sounds. Heart sound was recorded by auscultation on the skin of the chest wall using three smartphones: Samsung Galaxy S5…
- Trial name
- NCT03273803
- Testing
- Heart sound recording using smartphone application
- Where
- South Korea
- Volunteers
- 46 people
- Sponsor
- Seoul National University Hospital
Aortic Aneurysm, Thoracoabdominal, Aortic Aneurysm, Abdominal
Effect of Remimazolam Versus Propofol Total Intravenous Anesthesia on Intraoperative Hemodynamic Stability in Patients Undergoing Thoracic or Abdominal Endovascular Aortic Repair
The purpose of this study is to compare two intravenous anesthetics, remimazolam and propofol, for their effects on intraoperative hemodynamic stability in patients undergoing thoracic or abdominal endovascular aortic repair.
- Conditions
- Aortic Aneurysm, Thoracoabdominal, Aortic Aneurysm, Abdominal, Intraoperative Hypotension, Hemodynamic Instability During Anesthesia
- Trial name
- NCT07806006
- Testing
- Remimazolam Besylate, propofol
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Seoul National University Hospital
Aortic Aneurysm of the Proximal Arch, Aortic Aneurysms Arch
Effects of Remimazolam on Postoperative Cognitive Dysfunction and Neuroinflammatory Biomarkers in Patients Undergoing Aortic Arch Surgery
The purpose of this study is to compare remimazolam- and propofol-based anesthesia for their effects on postoperative cognitive dysfunction in patients undergoing aortic arch surgery.
- Conditions
- Aortic Aneurysm of the Proximal Arch, Aortic Aneurysms Arch, Aortic Arch Disease, Postoperative Delirium (POD)
- Trial name
- NCT07816068
- Testing
- Remimazolam Besylate, propofol
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Hospital
Spinal Cord Injuries (SCI)
A Rehabilitation Data Collection Study in Patients With Spinal Cord Injury
The goal of this observational study is to build a rehabilitation registry for people with spinal cord injury (SCI) in Korea and to create foundational data for predicting patients' long-term function.
- Trial name
- NCT07901985
- Where
- South Korea
- Volunteers
- 250 people
- Sponsor
- Seoul National University Hospital
Coronary Artery Disease (CAD)
TRADENT Scoring Balloon Versus Non-scoring Balloon for Lesion Preparation in DCB-Based Coronary Intervention
This study will compare the effectiveness of the TRADENT™ coronary scoring balloon with a conventional non-scoring balloon for lesion preparation in patients undergoing a drug-coated balloon (DCB)-first percutaneous coronary…
- Trial name
- TRAD-PREP (NCT07899021)
- Testing
- TRADENT Scoring Balloon, Conventional Non-Scoring Coronary Balloon
- Volunteers
- 580 people
- Sponsor
- Ulsan University Hospital
Anti-N-methyl-D-aspartate Receptor (NMDAR) Encephalitis (ANRE), Anti-N-methyl-D-aspartate Receptor (NMDAR) Antibody-associated Psychiatric Disease
A Study in Participants With Anti-NMDAR Encephalitis and Anti-NMDAR Autoantibody-Associated Psychiatric Disease
This study will evaluate the safety, tolerability, preliminary efficacy and pharmacokinetics (PK) of ART5803 in adult participants with a confirmed diagnosis of anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis (ANRE) or…
- Conditions
- Anti-N-methyl-D-aspartate Receptor (NMDAR) Encephalitis (ANRE), Anti-N-methyl-D-aspartate Receptor (NMDAR) Antibody-associated Psychiatric Disease, Autoimmune Encephalitis
- Trial name
- NCT07093333
- Testing
- ART5803, ART5803-Cohort D
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Arialys Australia Pty Ltd
Fecal Incontinence
The Safety and Efficacy of 5-HT3 Receptor Antagonist (Ramosetron) for the Treatment of Fecal Incontinence
This multicenter clinical trial evaluates ramosetron and psyllium for adults with fecal incontinence, which is the accidental loss of stool.
- Trial name
- SERAFI (NCT06166615)
- Testing
- Ramosetron, Psyllium
- Where
- 3 sites in South Korea
- Volunteers
- 147 people
- Sponsor
- Seoul National University Hospital
Vaccination, Respiratory Syncytial Virus (RSV)
Immunogenicity and Safety of Respiratory Syncytial Virus Vaccine in Lung Transplant Recipients
The purpose of this study is to compare the immunogenicity and safety of respiratory syncytial virus (RSV) vaccination between lung transplant recipients and immunocompetent adults and to provide evidence to guide RSV vaccination…
- Conditions
- Vaccination, Respiratory Syncytial Virus (RSV), Lung Transplant Recipient
- Trial name
- NCT07895394
- Testing
- RSVPreF3 vaccination
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Hospital
Bipolar Disorder (BD), Major Depressive Diorder
Stress Management With Real-time Bio-signal Biofeedback
The goal of this clinical trial is to learn if the real-time bio-signal monitoring device (Neuronicle FX2 device), combined with mindfulness-based cognitive therapy (MBCT), helps manage stress and improves symptoms of mood…
- Trial name
- NCT06616116
- Testing
- Biosignal feedback
- Where
- South Korea
- Volunteers
- 140 people
- Sponsor
- Seoul National University Hospital
Preterm
Efficacy of a Video-based, Parent-centered Home Developmental Intervention for Infants at High Risk for Developmental Delay: a Multicenter Randomized Controlled Trial
The purpose of this study is to determine whether the Motor Composite Score on the Bayley-III (administered at 6 months of corrected age) shows significant improvement in an intervention group-receiving usual care combined with a…
- Trial name
- NCT07882199
- Testing
- Family-centered developmental training intervention
- Volunteers
- 170 people
- Sponsor
- Seoul National University Hospital
Gastric Cancer
Assessment of a Robotic Distal Gastrectomy on Non-inferiority of N2 Area Nodal Dissection
Designed as a single arm multi-center prospective phase II trial, which evaluates the number of dissected lymph nodes in the N2-area as a surrogate parameter for adequate D2 lymphadenectomy in robotic distal gastrectomy (RDG) for…
- Trial name
- AaRon (NCT02572050)
- Testing
- Distal Gastrectomy with D2 LND
- Where
- 2 sites in South Korea
- Volunteers
- 87 people
- Sponsor
- National Cancer Center, Korea
Breast Neoplasms
Window of Opportunity Trial of Neoadjuvant Olaparib and Durvalumab for Triple Negative or Low ER+ Breast Cancer
Window of Opportunity Trial of Olaparib and Durvalumab (MEDI4736) before Standard Neoadjuvant Chemotherapy for Stage II/III Triple Negative or Low ER+ Breast Cancer
- Trial name
- NCT03594396
- Testing
- Olaparib, Durvalumab
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Seoul National University Hospital
Coronary Artery Disease (CAD)
1-Month Versus 6-Month Dual Antiplatelet Therapy After Successful Drug-Coated Balloon-Only Percutaneous Coronary Intervention
This study will compare the clinical outcomes of a 1-month dual antiplatelet therapy (DAPT) strategy with a standard 6-month DAPT strategy in patients undergoing successful drug-coated balloon-only percutaneous coronary…
- Trial name
- ADAPT-DCB (NCT07879430)
- Testing
- 1-Month DAPT, 6-Month DAPT
- Volunteers
- 1,258 people
- Sponsor
- Ulsan University Hospital
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