Clinical trials: sponsored by Taipei Medical University
Dementia Care Education, Students, Nursing
The Effectiveness of Comic-based Learning Materials on Nursing Students' Knowledge, Attitudes, and Confidence in Dementia Care
This randomized controlled trial aims to evaluate the effectiveness of comic-based dementia care educational materials in improving nursing students' knowledge, attitudes, and confidence in dementia care.
- Conditions
- Dementia Care Education, Students, Nursing, Education, Nursing, Dementia
- Trial name
- NCT07922109
- Testing
- Comic-Based Dementia Care Education, Text-Based Dementia Care Education
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Occupational Stress, Sleep Quality
Curcumin Nano Patch and Autonomic Function in Shift-Working Healthcare Professionals
This randomized, open-label, placebo-controlled crossover study compares a curcumin-containing patch with a cooling placebo patch without curcumin in healthcare professionals who work rotating shifts.
- Trial name
- NCT07910279
- Testing
- Curcumin Nano Patch
- Where
- Taiwan
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Biliary Tract Cancer (BTC)
Daraxonrasib in Asian RAS-mutant Biliary Tract Cancer
The trial will assess the efficacy, safety, and tolerability of daraxonrasib monotherapy in Asian patients with RAS-mutated advanced biliary tract cancer in second-line treatment.
- Trial name
- NCT07908550
- Testing
- Daraxonrasib
- Where
- Taiwan
- Volunteers
- 55 people
- Sponsor
- National Health Research Institutes, Taiwan
Advanced Solid Malignancies
Liposomal Irinotecan Plus Cisplatin in Patients With Advanced or Metastatic Solid Malignancies
Phase I trial, Multiple centers, open-label, non-randomized single-arm study
- Trial name
- ICONIC (NCT07782346)
- Testing
- Liposomal Irinotecan Plus Cisplatin
- Where
- 6 sites in Taiwan
- Volunteers
- 44 people
- Sponsor
- National Health Research Institutes, Taiwan
Pearson Syndrome, Mitochondria DNA Deletion
Investigation of the Treatment of Patients With Mitochondrial Defects by Assisted Reproductive Technology
Mitochondria are important organelles that generate energy (ATP) in human and mammalian cells. Currently, there are more than 50 kinds of diseases known to be related to mitochondrial defects in Taiwan.
- Trial name
- NCT07911306
- Testing
- Maternal spindle transfer
- Where
- Taiwan
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Taipei Fertility Center
Hip Fracture Surgeries, High Risk Population of Hip Fractures
A Decision Support Tool for Common Surgical Fixations of Hip Fractures
This study aims to improve how patients, families, and healthcare professionals work together to make important medical decisions, especially in cases involving hip fractures.
- Conditions
- Hip Fracture Surgeries, High Risk Population of Hip Fractures, Decision Surrogate of Hip Fixations
- Trial name
- NCT07909876
- Testing
- IDeA for Hip Fracture, Non-IDeA for hip fracture
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Food Effect in Healthy Volunteers
A Phase 1, Open-Label, Two-Stage, Food Effect Study to Assess the Safety, Tolerability, and Pharmacokinetics of EI-1071 Under Fasted or Fed Conditions in Healthy Volunteers
This is a phase 1, open-label, two-stage, sequential food effect study to evaluate the safety, tolerability, and PK of EI-1071 under fasted or fed conditions in HVs.
- Trial name
- NCT07903337
- Testing
- EI-1071
- Where
- Taiwan
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Elixiron Immunotherapeutics Inc.
Hemodialysis Patient, Fatigue
The Effects of an App-based Acupressure on Alleviating Fatigue, Pruritus, and Sleep Quality Among Hemodialysis Patients
Objectives: To evaluate the effectiveness of an app-based self-guided acupressure intervention in alleviating fatigue and pruritus, and in improving sleep quality among hemodialysis patients.
- Trial name
- NCT07259369
- Testing
- app-based acupressure
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Taipei Medical University
Insomnia
AI-Driven Digital Therapeutic for Insomnia: Development and Clinical Validation
Insomnia is a prevalent global health problem, with approximately one in five Taiwanese adults chronically affected. Prolonged use of sedative-hypnotic medications carries risks of adverse effects, dependence, and unnecessary…
- Trial name
- BBTI app (NCT07880561)
- Testing
- Digital BBTI-Based Sleep Management, AI-Assisted Sleep Education and Personalized Guidance
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Medical University
Hearing Loss, Cognitive Impairment
Auditory-Cognitive Optimization Care Program for Older Adults With Hearing Loss and Cognitive Impairment
Hearing loss and cognitive impairment are common and interrelated health problems that may affect communication, information processing, attention, psychological well-being, daily functioning, and quality of life.
- Trial name
- A-COP (NCT07869745)
- Testing
- Auditory-Cognitive Optimization Care Program (A-COP), Hearing Management and Newspaper-Reading Activities
- Where
- Taiwan
- Volunteers
- 76 people
- Sponsor
- Taipei Medical University
Hepatocellular Carcinoma
Curative Therapy After Atezolizumab and Bevacizumab Treatment for Unresectable Hepatocellular Carcinoma
Combination immunotherapy is currently the standard first-line systemic treatment for unresectable hepatocellular carcinoma (HCC).
- Trial name
- NCT07091942
- Where
- Taiwan
- Volunteers
- 243 people
- Sponsor
- National Taiwan University Hospital
Compassion
Compassion-Based Intervention for Lung Cancer Caregivers (CBI-LCC)
Objectives: This 3-year study aims to develop, refine, and evaluate a brief compassion-based intervention specifically designed for family caregivers of lung cancer patients.
- Trial name
- CBI-LCC (NCT06930313)
- Testing
- Brief Compassion-Based Intervention (BCI), Telephone-Based Support and Education (TSE)
- Where
- Taiwan
- Volunteers
- 84 people
- Sponsor
- Taipei Medical University
Frailty Syndrome, Older Adults
Feasibility and Effects of Inspiratory Muscle Training Combined With Blood Flow Restriction for Frail Older Adults
This randomized controlled trial study aims to evaluate the feasibility and preliminary efficacy of a combined inspiratory muscle training (IMT) and blood flow restriction (BFR) intervention in frail older adults.
- Conditions
- Frailty Syndrome, Older Adults, Blood Flow Restriction (BFR) Training Effects, Inspiratory Muscle Training
- Trial name
- NCT07573995
- Testing
- Exercise
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Medical University
Cardiovascular-kidney-metabolic Syndrome
AI Chatbot-Enabled ePRO Monitoring and Nurse-Led Self-Management for Early-Stage Cardiovascular-Kidney-Metabolic Syndrome
This randomized controlled trial will evaluate the effectiveness of an AI chatbot-enabled electronic patient-reported outcome (ePRO) monitoring and nurse-led self-management intervention for adults with early-stage…
- Trial name
- NCT07577284
- Testing
- AI chatbot-enabled nurse-led program., Usual Care
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taipei Medical University
Gene Expression, Nutrigenomics
The Improving Effects of French Maritime Pine Bark Extract on Antioxidation and Anti-inflammation a in Post-menopausal Women Based on Nutrigenomic Approach
The goal of this clinical trial is to investigate whether French maritime pine bark extract (FMPBE) supplementation can improve antioxidant capacity and reduce inflammation in postmenopausal women aged 40-75 years.
- Trial name
- NCT07855198
- Testing
- French maritime pine bark extract
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Insomnia
The Effect of Nurse-Led Mobile APP-based Brief Behavioral Therapy for Insomnia in Older Adults
Background: Insomnia affects 20%-30% of older adults and is linked to increased fall risk, cognitive decline, and cardiovascular disease.
- Trial name
- BBTI App (NCT07842250)
- Testing
- Nurse-Led Mobile BBTI, Face-to-Face BBTI, Sleep Education
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Medical University
Clinical Reasoning
Effectiveness of Serious Games on Nursing Students' Clinical Reasoning
This randomized controlled trial aims to evaluate the effectiveness of serious game-based learning compared with conventional learning in improving clinical reasoning among nursing students in Vietnam.
- Trial name
- NCT07806747
- Testing
- Serious game - based learning, Conventional teaching
- Where
- Vietnam
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Do Thi Kim Chi
Prematurity, Low Birth Weight
Paternal Involvement in Nursing Guidance and Breastfeeding Self-Efficacy in Mothers of High-Risk Newborns
This study aims to evaluate whether a structured nursing guidance program that increases fathers' participation in the care of hospitalized high-risk newborns improves maternal outcomes compared with routine nursing care.
- Conditions
- Prematurity, Low Birth Weight, Respiratory Distress Syndrome, Newborn, Neonatal Hyperbilirubinemia
- Trial name
- NCT07834008
- Testing
- step-by-step parent education, active father participation in breastfeeding support
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Malignant Biliary Obstruction, Malignant Biliary Stricture
Endoscopic Ultrasound Guided Hepaticogastrostomy With or Without Antegrade Stenting for Palliation of Malignant Distal Biliary Obstruction: Randomized Controlled Trial
The purpose of this study is to compare the efficacy and safety between EUS-HGAS and EUS-HGS. We hypothesized that EUS-HGAS provides lower recurrent biliary obstruction (RBO) rate but with a comparable safety profile to EUS-HGS.
- Trial name
- EASE-MBO (NCT07832045)
- Testing
- HGAS, HGS
- Where
- Taiwan
- Volunteers
- 88 people
- Sponsor
- National Taiwan University Hospital
Sarcopenia
Lower-Limb Rehabilitation Robot Training for Sarcopenia
The goal of this clinical trial is to learn whether lower-limb rehabilitation robot training combined with nutrition education can improve muscle mass and physical function in adults aged 60 years or older with sarcopenia.
- Trial name
- NCT07830472
- Testing
- Lower-Limb Rehabilitation Robot Training, Nutrition Education, Usual Care Exercise
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Taipei Medical University Hospital