Clinical trials: sponsored by Tanta University
Epidermolysis Bullosa (EB), Chronic Wounds
Topical Insulin Versus Irradiated Amniotic Fluid Gel for Wound Healing in Epidermolysis Bullosa
This study aims to evaluate and compare the safety and efficacy of topical insulin and topical irradiated amniotic fluid gel in promoting wound healing in patients with epidermolysis bullosa (EB).
- Conditions
- Epidermolysis Bullosa (EB), Chronic Wounds, Wound Healing
- Trial name
- EB-INS-AFG (NCT07907523)
- Testing
- Topical Insulin (Actrapid®), Topical Irradiated Amniotic Fluid Gel, No active study treatment
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Irreversible Pulpitis
Effect of Temperature Elevation on the Antimicrobial Efficacy of Two Root Canal Irrigants in Primary Root Canal Infections: A Randomized Controlled Clinical Trial
evaluate the antimicrobial efficacy of preheated sodium hypochlorite and dexamethasone sodium phosphate and at room temperature in patients with primary root canal infection.
- Trial name
- NCT07906925
- Testing
- Dexamethasone Sodium Phosphate 10 MG/ML, Sodium Hypochlorite 2,5%
- Volunteers
- 40 people
- Sponsor
- Tanta University
SBP - Spontaneous Bacterial Peritonitis
Nitazoxanide in Spontaneous Bacterial Peritonitis
Spontaneous bacterial peritonitis (SBP) is a life-threatening complication of liver cirrhosis characterized by infection of ascitic fluid in the absence of an evident intra-abdominal source.
- Trial name
- NCT07808450
- Testing
- Nitazoxanide (NTZ)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Inflammatory Bowel Diseases
Metformin in Patients With Ulcerative Colitis Treated With Mesalamine
Ulcerative colitis (UC) is an idiopathic, chronic inflammatory disease characterized by diffused inflammation of the colon and rectum mucosa, however, the exact underlying mechanisms of UC remain poorly understood.UC is strongly…
- Trial name
- NCT05553704
- Testing
- Metformin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
SBP - Spontaneous Bacterial Peritonitis
N-Acetylcysteine in the Management of Spontaneous Bacterial Peritonitis
Spontaneous bacterial peritonitis (SBP) is one of the most serious infectious complications of liver cirrhosis and ascites. It affects approximately 10-30% of hospitalized patients with decompensated cirrhosis and carries an…
- Trial name
- NCT07803952
- Testing
- NAC
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Depressive Disorder
Clinical Study to Evaluate the Possible Efficacy of Dapagliflozin and Atorvastatin in Patients With Major Depressive Disorders
Major depressive disorder (MDD) is a significant cause of disability that affects approximately 16% of the world's population and is associated with chronic inflammation.
- Trial name
- NCT05792540
- Testing
- Fluoxetine 20 mg, Dapagliflozin 10mg Tab, Atorvastatin 80mg
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Tanta University
Acne Scars - Atrophic
Comparative Study of The Efficacy and Safety of Subcision Combined With Injection of Exosomes Versus Subcision Alone in Treatment of Atrophic Post- Acne Scars.
This split-face comparative prospective study was carried out on 20 patients presenting with atrophic post-acne scars. All participants were subjected to full history taking, general and dermatological examination, photographing…
- Trial name
- NCT07906509
- Testing
- Subcision plus exosome injection, Subcision
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Tanta University
Inflammatory Bowel Diseases
Atorvastatin in Patients With Ulcerative Colitis
Ulcerative colitis (UC) is an idiopathic, chronic inflammatory disease characterized by diffused inflammation of the colon and rectum mucosa; however, the exact underlying mechanisms of UC remain poorly understood.
- Trial name
- NCT05561062
- Testing
- Atorvastatin 80mg
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Parkinson Disease
Clinical Study to Evaluate the Possible Efficacy of Metformin in Patients With Parkinson's Disease
Parkinson's disease (PD) is one of the most common neurodegenerative diseases characterized by the progressive loss of dopaminergic (DA) neurons in the substantia nigra compacta (SNc) and aggregation of Lewy bodies in neurons.
- Trial name
- NCT05781711
- Testing
- levodopa-carbidopa, Metformin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Dermatologic Disease
A Comparative Clinical Trial Evaluating the Effect and Safety of Tacrolimus Versus Hydrocortisone
One of the most frequent skin conditions is atopic dermatitis (AD), characterized by its pruritic inflammation effect. Where the prevalence of AD increased in the last three decades by two or three folds worldwide, especially in…
- Trial name
- NCT05607901
- Testing
- Tacrolimus ointment, Hydrocortisone 1% cream
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Breast Feeding, Maternal and Infant Bonding
Empowering First-Time Mothers
This randomized controlled trial aims to evaluate the effect of digital lactation nursing support on breastfeeding achievement and maternal-infant outcomes among first-time mothers.
- Trial name
- Empowering (NCT07900932)
- Testing
- digital lactation nursing support program
- Where
- 2 sites in Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tanta University
Voice, Therapy
Voice Therapy in Reactive Benign Vocal Fold Polyp and Injection of Steroid
The aim of this study is to compare the efficacy between Voice Therapy and Injection of Steroid in Reactive Benign Vocal Fold polyp.
- Conditions
- Voice, Therapy, Vocal Fold Polyp, Steroid Injection
- Trial name
- NCT07904988
- Testing
- Group 1: Patients with reactive benign vocal fold polyp will be treated by Voice Therapy, Group 2: Patients with reactive benign vocal fold polyp will be treated by Injection of steroid
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Tonsillitis Chronic, Tonsillitis Recurrent
Adult Tonsillectomy Techniques: Blunt Dissection Vs Bipolar Radiofrequency
The aim of this study is to assess the effectiveness of bipolar radiofrequency techniques of tonsillectomy in adults.
- Trial name
- NCT07903233
- Testing
- Blunt Dissection, Bipolar Radiofrequency
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Tanta University
Acne
A Split-Face Comparative Study of Mono Threads Versus Combination With Plasma Gel for the Treatment of Post-Acne Scars
This study aims to evaluate and compare the efficacy and safety of mono threads alone versus mono threads combined with plasma gel for the treatment of atrophic post-acne scars.
- Trial name
- NCT07903012
- Testing
- polydioxanone (PDO) mono threads, Mono Threads with Plasma Gel
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Tanta University
NAFLD (Nonalcoholic Fatty Liver Disease)
Evaluating the Safety and Efficacy of Rupatadine in the Treatment of Nonalcoholic Fatty Liver Disease Patients.
NAFLD is characterized by excessive hepatic fat accumulation without other recognized causes of increased fat content (e.g., alcohol, virus, drugs, and autoimmunity).
- Trial name
- NCT07900100
- Testing
- Rupatadin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Rheumatoid Arthritis (RA
Efficacy and Safety of Dapagliflozin as an Adjunct to Conventional Disease-Modifying Antirheumatic Drugs in Patients With Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a long-standing autoimmune inflammatory disease marked by continuous synovial inflammation, which contributes to progressive cartilage and bone damage, eventually resulting in joint destruction.
- Trial name
- NCT07901309
- Testing
- Dapagliflozin (10mg Tab)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Chronic Anal Fissure
Low Versus High Dose OnabotulinumtoxinA for Chronic Anal Fissure
This prospective single-center cohort study describes short-term and one-year clinical outcomes of two routine doses of OnabotulinumtoxinA (20 units versus 50 units) for chronic anal fissure refractory to conservative therapy.
- Trial name
- NCT07543315
- Testing
- OnabotulinumtoxinA
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Tanta University
Linear Atrophic Scars
Comparative Analysis of Intralesional Platelet-Rich Plasma, NPH Insulin, and Vitamin C- A New Horizon and Future Hope for Linear Atrophic Scar Management
The aim of this clinical trial is to evaluate the efficacy and safety of platelet-rich plasma, insulin and vitamin C in the management of linear atrophic scars.
- Trial name
- NCT07901283
- Testing
- Intradermal injection of autologous platelet rich plasma, Intradermal injection of NPH insulin, Intradermal injection of Vitamin C
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Aya Ashraf Fouda
NAFLD (Nonalcoholic Fatty Liver Disease)
Evaluating the Safety and Efficacy of Roflumilast in the Treatment of Nonalcoholic Fatty Liver Disease Patients
Nonalcoholic fatty liver disease (NAFLD) is a global public health concern, and the leading cause of chronic liver disease, especially in developed countries.
- Trial name
- NCT07900087
- Testing
- Roflumilast
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Post-Traumatic Atrophic Scar, Atrophic Scar
Nanofat Injection and Fractional CO2 Laser for Post-Traumatic Atrophic Scars
Post-traumatic atrophic scars are characterized by skin depressions caused by loss of collagen and can lead to cosmetic and psychological concerns.
- Conditions
- Post-Traumatic Atrophic Scar, Atrophic Scar, Scar
- Trial name
- NANOCO2-PTS (NCT07679217)
- Testing
- Autologous Nanofat Injection, Fractional CO2 Laser
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
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