Clinical trials: sponsored by Universidad Complutense de Madrid
Lung Transplantation
Electrostimulation Program for Lung Transplant Recipients in the ICU
This study aims to evaluate rectus femoris muscle mass in lung transplant recipients and the effect of a training program during ICU admission based on the use of electrical muscle stimulation (EMS)
- Trial name
- NCT05410522
- Testing
- EMS Program
- Where
- Spain
- Volunteers
- 58 people
- Sponsor
- Universidad Complutense de Madrid
Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension
Home-based Inspiratory Muscle Training in Pulmonary Hypertension
The main objective of this study is to determine whether an 8-week inspiratory muscle training (IMT) programme, delivered at home through telerehabilitation, improves ventilatory efficiency (VE/VCO2 slope) compared with a sham…
- Trial name
- SLOPE-PH (NCT07917416)
- Testing
- Inspiratory muscle training
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Complutense de Madrid
Trauma, Psychological, Traumatic Stress Disorder
Magnetoencephalographic Correlates of Clinical Change After Cognitive Processing Therapy in Adults With PTSD
Cognitive Processing Therapy (CPT) is a first-line, evidence-based trauma-focused treatment for posttraumatic stress disorder (PTSD), but the clinical and neurophysiological mechanisms underlying therapeutic response remain…
- Trial name
- REC-HEALING-TR (NCT07917377)
- Testing
- Behavioral: Cognitive Processing Therapy (individual), Magnetoencephalography (MEG)
- Where
- 2 sites in Spain
- Volunteers
- 10 people
- Sponsor
- Universidad Complutense de Madrid
Diabetic Foot Disease, Recurrence
Better Care Closer to Home: Enhancing Primary and Community Care
60 million people in Europe have diabetes (DM) and up to 34% (20.4 million) of them are at risk of developing diabetic foot ulcers (DFUs) in their lifetime (1).
- Trial name
- NCT07905664
- Testing
- Path Active™, a smart insole system designed to reduce the risk of plantar ulceration in patients with diabetic foot disease
- Where
- 3 sites in Canada, Denmark and 1 more
- Volunteers
- 84 people
- Sponsor
- Universidad Complutense de Madrid
Nitrate, Placebo - Control
Beetroot Juice and Neuromuscular Performance in Female Basketball Players
A randomized, double-blind, placebo-controlled study investigates the effects of 5 days of nitrate-rich beetroot juice supplementation (70 mL·day-¹; 6.4 mmol NO₃-·day-¹) on physical performance in female basketball players.
- Trial name
- BASKET_BEET (NCT07833579)
- Testing
- Beetroot juice supplementation
- Where
- Spain
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universidad Pontificia Comillas
Trauma, Psychological, Traumatic Stress Disorder
Group Cognitive Processing Therapy for Women Survivors of Gender-Based Violence: Feasibility Study
Introduction: Post-traumatic stress disorder (PTSD) is a global health challenge requiring effective, evidence-based interventions, such as Cognitive Processing Therapy (CPT).
- Trial name
- HEALING-TRAUMA (NCT07897903)
- Testing
- Group CPT + TAU (Experimental)
- Volunteers
- 10 people
- Sponsor
- Universidad Complutense de Madrid
MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, MASH - Metabolic Dysfunction-Associated Steatohepatitis
Exercise for an Aging Liver (EXALIVER)
The goal of this clinical trial is to learn how physical exercise affects liver health in adults with metabolic dysfunction-associated steatotic liver disease (MASLD) or at-risk metabolic dysfunction-associated steatohepatitis…
- Conditions
- MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, MASH - Metabolic Dysfunction-Associated Steatohepatitis, Liver Fibrosis/NASH
- Trial name
- EXALIVER (NCT07467512)
- Testing
- Exercise, Usual Care
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Consorcio Centro de Investigación Biomédica en Red (CIBER)
Moral Distress, Moral Injury
Coping and Adaptation for Recovery From Moral Injury: A Group Intervention for Clinical Psychology Residents
Moral distress may arise when health care professionals are unable to act in accordance with their professional values or believe that they have participated in, witnessed, or been unable to prevent situations that conflict with…
- Trial name
- CARE-MI (NCT07887581)
- Testing
- CARE-MI Group Intervention
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Acute Stress Symptoms, Sexual Violence
The Effectiveness of a Brief Early Intervention of Acute Stress Syndrome Stabilization Protocol for Victims of Sexual Violence (ASSYST-SV).
TThe main objectives of this research project are twofold: (1) to conduct a narrative review of the scientific literature on the efficacy and effectiveness of psychological interventions for reducing acute post-traumatic stress…
- Trial name
- ASSYST-SV (NCT07112040)
- Testing
- Behavioral - ASSYST-VS Protocol
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Moral Injury, TEPT
A Comprehensive Group Intervention for Psychosocial Personnel at Risk of Stress and Moral Injury
The objective of this randomized controlled trial is to evaluate the effectiveness of the CARE-MI group intervention in reducing symptoms of post-traumatic stress and moral injury in support staff working with individuals…
- Trial name
- CARE-MI-PsychS (NCT07140263)
- Testing
- CARE MI, TAU: Treatment as usual
- Where
- Spain
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Multiple Myeloma, Breathing Techniques
Effects of Controlled Breathing Added to Therapeutic Exercise in Multiple Myeloma
A randomized, parallel, double-blind, controlled, multicenter clinical trial with two intervention arms. Two groups of participants will be included, both receiving a therapeutic exercise intervention and an educational session…
- Conditions
- Multiple Myeloma, Breathing Techniques, Breathing Exercises, Exercise Activity
- Trial name
- NCT07312942
- Testing
- Controlled breathing exercise protocol + therapeutic exercise + initial education session, Therapeutic exercise + initial education session
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Universidad Complutense de Madrid
Multiple Myeloma (MM), Breathing Techniques
Effects of Controlled Breathing on Cardiorespiratory Variables in Multiple Myeloma
A randomized, parallel, double-blind, controlled, clinical trial. Two groups of participants will be included, both receiving a therapeutic exercise intervention and an educational session on the importance of proper breathing…
- Conditions
- Multiple Myeloma (MM), Breathing Techniques, Breathing Exercises, Exercise Activity
- Trial name
- NCT07376733
- Testing
- Controlled breathing exercise protocol + therapeutic exercise + initial education session, Therapeutic exercise + initial education session
- Where
- Spain
- Volunteers
- 26 people
- Sponsor
- Universidad Complutense de Madrid
Periodontal Defects After Third Molar Extraction, Periodontal Disease
Comparison of Autologous Tooth and Bovine Xenograft in Periodontal Healing After Mandibular Third Molar Extraction
This study investigates the healing of periodontal defects on the distal surface of the second lower molars after the surgical extraction of impacted third molars.
- Trial name
- NCT07824518
- Testing
- Autologous Tooth Graft
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Keratinized Mucosa Deficiency, Peri-implant Soft Tissue
Apical Flap Repositioning vs. Mucosa Excision With Free Gingival Grafts for Peri-Implant Keratinized Mucosa Augmentation
The goal of this clinical trial is to learn which surgical technique works better to increase the amount of firm gum tissue (called keratinized mucosa) around dental implants in adults.
- Conditions
- Keratinized Mucosa Deficiency, Peri-implant Soft Tissue, Dental Implants
- Trial name
- FGGIF (NCT07772414)
- Testing
- Free gingival graft with apical flap repositioning, Free gingival graft with vestibular mucosa excision
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Barcelona
Obesity & Overweight
NutriTrack: AI-Assisted Nutritional Tracking in the Obesity Clinic
NutriTrack is a digital health application designed to support nutritional and behavioral tracking in patients with obesity followed in an outpatient obesity clinic.
- Trial name
- NUTRITRACK (NCT07588620)
- Testing
- NutriTrack digital health application
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- Francisco José García González
Lung Transplant Recipients, Muscle Weakness
Efficacy of Early Inspiratory Muscle Training in Lung Transplanted Patients
Lung transplantation is an effective therapeutic option in the end-stage of chronic respiratory diseases. Lung transplantation improves lung function in terms of capacity and volume.
- Conditions
- Lung Transplant Recipients, Muscle Weakness, Respiratory Insufficiency, Pulmonary Rehabilitation
- Trial name
- NCT05271019
- Testing
- Threshold load device
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- Puerta de Hierro University Hospital
Cognitive Performance, Academic Performance
Acute Effects of Active Breaks and Physically Active Learning in University Students
This multicenter randomized crossover study will examine the acute effects of four classroom break conditions on executive functions, immediate academic performance, perceived exertion, and interest-enjoyment in university…
- Trial name
- PAL UNI (NCT07809750)
- Testing
- Sedentary Academic Review, Active Break, Physically Active Learning
- Where
- Spain
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Shoulder Pain
Dry Needling or Percutaneous Electrolysis for Managing Myofascial Trigger Points?
Dry needling (DN) and percutaneous electrolysis (PE) are minimally invasive physiotherapy techniques commonly used for the management of myofascial trigger points.
- Trial name
- PEDN (NCT07637760)
- Testing
- Dry needling, Percutaneous electrolysis (Low Intensity - Long Time), Manual therapy
- Where
- 2 sites in Spain
- Volunteers
- 60 people
- Sponsor
- Universidad Complutense de Madrid
Beta Alanine Supplementation, Placebo - Control
Beta-Alanine Effects on Neuromuscular and Cardiovascular Performance in Female Rugby Players
This study will examine the effects of beta-alanine supplementation on physical performance in female rugby players, who will ingest 4.8 grams/day over a four-week period.
- Trial name
- BA_RUGBY (NCT07809321)
- Testing
- Beta-Alanine
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Pontificia Comillas
Inflamatory Bowel Disease (Crohn's and Ulcerative Colitis), Inflamatory Bowel Disease
Physical Activity and Fitness in Pediatric Inflammatory Bowel Disease
Pediatric inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is a chronic condition associated not only with intestinal inflammation but also with reduced physical fitness, fatigue, impaired…
- Trial name
- PAFIT-IBD (NCT07484620)
- Testing
- Physical Activity Intervention
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Universidad Complutense de Madrid