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Drug or intervention

Remifentanil Clinical Trials

Studies that test Remifentanil, alone, with other treatments or as the comparison.

1,167 registered studies

In numbers

Open to volunteers
154
Active
170
With results posted
70
All registered
1,167

Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.

Open to volunteers

All 154
  • Airway Management, Supraglottic Airway Device Insertion

    Effect of Neuromuscular Blocking Agent Use on Video Laryngeal Mask Airway Insertion

    • Not yet recruiting
    • Age: 18 to 80 years
    • Phase 4

    This study aims to investigate whether the administration of a neuromuscular blocking agent (rocuronium) improves the anatomical positioning of a third-generation video laryngeal mask airway (video LMA) in adult patients…

    Conditions
    Airway Management, Supraglottic Airway Device Insertion, Laryngeal Mask Airways, Anesthesia, General
    Trial name
    NCT07894029
    Testing
    Rocuronium, Standard Anesthesia Induction (Propofol and Remifentanil)
    Where
    Turkey (Türkiye)
    Volunteers
    128 people
    Sponsor
    Hacettepe University
    Can I take part? NCT07894029
  • Dexmedetomidine, Total Intravenous Anesthesia

    The Impact of a Dexmedetomidine Perfusion on Intraoperative Remifentanil Consumption

    • Recruiting
    • Age: 18 to 80 years

    Opioids analgesic are the gold standard for intraoperative pain management. Their short- and long-term adverse effect motivate anesthesiologists to explore opioid sparing strategies.

    Conditions
    Dexmedetomidine, Total Intravenous Anesthesia, Remifentanil Consumption, Remifentanil
    Trial name
    DEXREM (NCT06684197)
    Testing
    Dexmedetomidine
    Where
    Canada
    Volunteers
    72 people, healthy volunteers welcome
    Sponsor
    Ciusss de L'Est de l'Île de Montréal
    Can I take part? DEXREM
  • Sedation, Analgesia Assessment

    A Prospective Multicenter Registry Study of Sedation and Analgesia in Critically Ill Patients

    • Enrolling by invitation
    • Age: 18 years and older
    • Observational study

    Sedation and analgesia are essential components of comprehensive care for intensive care unit (ICU) patients, particularly those receiving invasive mechanical ventilation, undergoing invasive procedures, or experiencing pain…

    Conditions
    Sedation, Analgesia Assessment, ICU
    Trial name
    NCT07885930
    Testing
    Not applicable- observational study
    Where
    China
    Volunteers
    2,000 people
    Sponsor
    Beijing Chao Yang Hospital
    Can I take part? NCT07885930
  • Opioid-Free Anesthesia, POCD

    Effect of Opioid-free Anesthesia on Sleep Quality, Cognitive Function and Recovery Quality After General Anesthesia in Elderly Patients

    • Not yet recruiting
    • Age: 60 years and older

    Postoperative cognitive dysfunction (POCD)is a common well disorder of the central nervous system after surgery, mainly manifested by impaired memory, spirit, language ability or other aspects of brain function.

    Conditions
    Opioid-Free Anesthesia, POCD, Recovery Quality, Sleep Quality
    Trial name
    NCT06493396
    Testing
    Opioid-free Analgesics, Opioid group
    Volunteers
    88 people
    Sponsor
    Beijing Friendship Hospital
    Can I take part? NCT06493396
  • Intravenous Anesthesia, Cholelithiasis

    Time to Loss of Consciousness With Remimazolam Versus Propofol for Anesthetic Induction in Laparoscopic Cholecystectomy

    • Recruiting
    • Age: 18 to 59 years
    • Phase 4

    The goal of this clinical trial is to compare two medicines used to induce general anesthesia in adults undergoing elective laparoscopic cholecystectomy.

    Trial name
    REMIPROP-LOC (NCT07717684)
    Testing
    Remimazolam, Propofol
    Where
    Brazil
    Volunteers
    66 people
    Sponsor
    Universidade Federal de Sergipe
  • Surgical Stress Response, Inflammation

    CoreSys Monitoring for Intraoperative Stress Management in Abdominal Hysterectomy

    • Recruiting
    • Age: 18 to 70 years
    • Injection or infusion
    • Medical device

    This randomized controlled trial evaluates whether intraoperative guidance using the CoreSys monitor reduces the surgical stress response in patients undergoing elective open abdominal hysterectomy.

    Conditions
    Surgical Stress Response, Inflammation, Anesthesia, Perioperative Care
    Trial name
    CORESTRESS (NCT07571473)
    Testing
    propofol, CoreSys Monitor, Remifentanil (Target-Controlled Infusion)
    Where
    Argentina
    Volunteers
    30 people
    Sponsor
    Hospital Provincial de Rosario
    Can I take part? CORESTRESS
  • Emergence Delirium, Post-Operative Cognitive Dysfunction

    Post Operative Cognitive Dysfunction After Oncologic Surgery

    • Recruiting
    • Age: 18 years and older
    • Observational study

    Aim of this trial is to define if Post-Operative Cognitive Dysfunction, detected analyzing changes between pre-operative and post-operative Neurocognitive Test, and Postoperative Delirium, relate to concentration of effector's…

    Trial name
    NCT03774420
    Where
    Italy
    Volunteers
    200 people
    Sponsor
    University of Padova
    Can I take part? NCT03774420
  • Pupillometry, Behavioral Pain Scale

    Pupillometry vs. BPS (Behavioral Pain Scale) for Analgesia Management in Inpatient Intensive Care Unit Patients on Invasive Mechanical Ventilation

    • Not yet recruiting
    • Age: 18 years and older

    Patients admitted to the intensive care unit (ICU) and receiving invasive mechanical ventilation (IMV) frequently require sedation and analgesia to ensure their comfort, prevent pain associated with invasive procedures, and…

    Conditions
    Pupillometry, Behavioral Pain Scale, Analgesia Assessment, Intensive Care Unit (ICU)
    Trial name
    GOLDEN EYE (NCT07867678)
    Testing
    PPI Measurement (Pupillary Pain Index), BPS Measurement (Behavioral Pain Scale)
    Where
    France
    Volunteers
    80 people
    Sponsor
    Centre Hospitalier Universitaire Dijon
    Can I take part? GOLDEN EYE
  • Tracheal Extubation, Cough

    Remifentanil Versus Remifentanil-Lidocaine for Tracheal Extubation After Thyroidectomy

    • Recruiting
    • Age: 18 to 65 years
    • Phase 4

    This randomized, double-blind clinical trial will compare the effects of remifentanil alone and remifentanil combined with intravenous lidocaine on the quality of tracheal extubation in adult patients undergoing elective…

    Trial name
    NCT07857356
    Testing
    remifentanil, Lidocaine %2 ampoule
    Where
    Turkey (Türkiye)
    Volunteers
    60 people
    Sponsor
    Pamukkale University
  • Intracerebral Hemorrhage

    REmifentanil And Dexmedetomidine for EarlY Intensive Blood Pressure Lowering in ICH.

    • Not yet recruiting
    • Age: 18 years and older

    Intracerebral hemorrhage (ICH) remains the most devastating subtype of stroke, with a case fatality rate of approximately 40% at one months post-onset, imposing a particularly heavy medical and economic burden on low- and…

    Trial name
    READY-ICH (NCT07695220)
    Testing
    Remifentanil and Dexmedetomidine, Guideline standard care
    Volunteers
    1,116 people
    Sponsor
    The Third Affiliated Hospital of Southern Medical University
    Can I take part? READY-ICH

Completed, with results posted

All 54
  • Minimal Flow Anesthesia, General Anaesthesia

    Minimal Flow Anesthesia and Infection Risk

    • Completed
    • Age: 18 to 65 years
    • Results posted

    This study is being done to find out if the heat and moisture that build up during minimal flow anesthesia can lead to the growth of germs (microorganisms) inside the anesthesia equipment.

    Conditions
    Minimal Flow Anesthesia, General Anaesthesia, Inhalation Anesthesia, Infection Risk
    Trial name
    NCT07092046
    Testing
    Sevoflurane (Volatile Anesthetic), Propofol 1%, Remifentanil 2 MG
    Where
    Turkey (Türkiye)
    Volunteers
    140 people, healthy volunteers welcome
    Sponsor
    Ankara City Hospital Bilkent
  • Morbid Obesity, Postoperative Pain

    Opioid-Free vs Opioid-Based Anesthesia in Bariatric Surgery

    • Completed
    • Age: 18 years and older
    • Results posted

    This prospective randomized controlled trial aims to compare the clinical effectiveness and safety of opioid-free anesthesia (OFA) versus traditional opioid-based anesthesia (OBA) in adult patients undergoing laparoscopic…

    Conditions
    Morbid Obesity, Postoperative Pain, Opioid Free Anesthesia, Bariatric Surgery
    Trial name
    NCT07337135
    Testing
    Opioid-Based Anesthesia (Remifentanil-Based Protocol), Opioid-Free Anesthesia (Dexmedetomidine-Ketamine-Lidocaine Protocol)
    Where
    Portugal
    Volunteers
    60 people
    Sponsor
    Hospital dos Lusíadas
    Can I take part? NCT07337135
  • Acute Pain, Chronic Pain

    Influence of Anesthetic Technique on Acute and Chronic Neuropathic Pain

    • Completed
    • Age: 18 years and older
    • Phase 4
    • Results posted

    Research suggests that the type of anesthesia used for surgery may affect intraoperative stress hormone levels. There is also data to support that an increased level of stress hormones leads to increased pain after surgery.

    Conditions
    Acute Pain, Chronic Pain, Hernia, Anesthesia, Intravenous
    Trial name
    NCT02527083
    Testing
    Propofol, Sevoflurane, Remifentanil
    Volunteers
    10 people
    Sponsor
    VA Pittsburgh Healthcare System
    Can I take part? NCT02527083
  • Anesthesia, Pain

    Near Infrared Spectroscopy Cortical Response to Noxious and Auditory Stimuli in Subjects Under General Anesthesia

    • Completed
    • Age: 12 to 30 years
    • Results posted

    The primary aim is to utilize near-infrared spectroscopy (NIRS) in patients under general anesthesia to measure changes in brain blood flow in the bilateral somatosensory cortices and the prefrontal cortices in response to…

    Trial name
    NCT02703090
    Testing
    Remifentanil, Normal saline
    Where
    United States
    Volunteers
    44 people
    Sponsor
    Boston Children's Hospital
    Can I take part? NCT02703090
  • Postoperative Delirium, Hemodynamic Instability

    Perioperative Multimodal General AnesTHesia Focusing on Specific CNS Targets in Patients Undergoing carDiac surgERies

    • Completed
    • Age: 60 years and older
    • Medical device
    • Results posted

    In the PATHFINDER 2 trial, the study investigators will test the intraoperative EEG-guided multimodal general anesthesia (MMGA) management strategy in combination with a postoperative protocolized analgesic approach to: 1.

    Conditions
    Postoperative Delirium, Hemodynamic Instability, Pain, Neurocognitive Dysfunction
    Trial name
    PATHFINDERII (NCT05279898)
    Testing
    EEG Monitoring, Ropivacaine, Ketamine
    Where
    United States
    Volunteers
    70 people
    Sponsor
    Beth Israel Deaconess Medical Center

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