Research institution
George Washington University Clinical Trials
Studies where George Washington University is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 35Obesity & Overweight, Respiratory Depression
Oxytocin for Respiratory Compromise and Hypoventilation Induced by Drugs
Drug overdose is a national crisis. The primary cause of death associated with opioids is opioid-induced respiratory depression.
- Conditions
- Obesity & Overweight, Respiratory Depression, Intranasal Drug Administration, Oxytocin
- Trial name
- ORCHID (NCT07902752)
- Testing
- Intranasal Oxytocin 40 i.u.
- Volunteers
- 100 people
- Sponsor
- George Washington University
Distal Radius Fractures
Impact of Early ADL Education on Outcomes Post DRF ORIF
This study is a randomized controlled trial (RCT). This RCT which will study the effect of performing daily activities early after a distal radius fracture being treated with surgical intervention of open reduction and internal…
- Trial name
- NCT06251206
- Testing
- ADL/Postoperative Instruction, Postoperative Instruction
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- George Washington University
Colorectal Cancer
Colorectal Cancer Screening in the Homeless
This study is designed to assess the effect of implementing a text messaging strategy for colorectal cancer screening among homeless persons aged 45-75 years, who are not up to date on colorectal cancer screening, in shelter…
- Trial name
- NCT07220018
- Testing
- mHealth for Colorectal cancer screening in Homeless Persons, Control SMS Messages
- Where
- United States
- Volunteers
- 588 people
- Sponsor
- George Washington University
Renal Failure, Coronary Artery Disease
Prevent Cardiac Surgery Associated AKI Trial
Prevent CSA-AKI (Cardiac Surgery Associated Acute Kidney Injury) trial is a double blinded randomized controlled trial, 242 patients undergoing elective cardiopulmonary bypass surgery (CPB)will either receive a placebo or daily…
- Conditions
- Renal Failure, Coronary Artery Disease, Surgery, Surgery-Complications
- Trial name
- NCT06620523
- Testing
- CoQ10 1200 mg orally with Glutathione 1000 mg orally
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- George Washington University
Smoking Cessation
ChatGPT-Supported Text Messaging Program for Smoking Cessation
The current research proposal aims to explore how a purpose driven LLM ChatGPT chatbot, BeFreeBot, might enhance an evidence-based text messaging smoking cessation program, BeFree.
- Trial name
- NCT07079306
- Testing
- BeFree+Bot, BeFree
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- George Washington University
Influenza, COVID-19
Flu COVID Vaccine Views
This study addresses a critical evidence gap relevant to implementation strategies for combination vaccines in health care settings.
- Conditions
- Influenza, COVID-19, Vaccination Willingness
- Trial name
- NCT07871448
- Testing
- Survey
- Where
- 2 sites in United States
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- George Washington University
HIV
Decision Support Tool to Integrate PrEP Into Emergency Departments
This project will explore the development of a personalized decision support tool to assist with pre-exposure prophylaxis (PrEP) initiation and persistence among patients identified in the emergency department (ED) and urgent…
- Trial name
- NCT07279129
- Testing
- Decision support tool, PrEP Delivery
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- George Washington University
MELAS Syndrome, Lebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus)
A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus)
This is a parallel arm non-randomized dose-escalation, open-label basket exploratory phase 1 clinical trial where Mitochondrial encephalopathy, lactic acidosis, stroke-like episodes (MELAS) and Leber's hereditary optic…
- Trial name
- NCT06792500
- Testing
- Glycerol Tributyrate
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- George Washington University
Wellbeing
Self-Help Plus Pilot Study, Colombia: Train2Care
This project will strengthen local capacity for mental health care in high-need settings in Colombia by culturally and linguistically adapting the Self-Help+ intervention and delivering participatory, supervised training.
- Trial name
- T2C (NCT07524309)
- Testing
- Self help plus
- Where
- Colombia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- George Washington University
Myasthenia Gravis (MG)
Feasibility of Remote Monitoring of Patients With Myasthenia Gravis
Myasthenia gravis is an autoimmune neuromuscular disorder characterized by fluctuating weakness, which can worsen suddenly without a clear predictor.
- Trial name
- ROME-MG (NCT07787247)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- George Washington University
Completed, with results posted
All –Myofacial Pain, Pain, Neck
Trigger Point Injections in Anterior Cervical Surgery
To achieve appropriate exposure for an anterior neck surgery (for example an Anterior Cervical Discectomy and Fusion or ACDF), patients are positioned supine with their neck extended.
- Conditions
- Myofacial Pain, Pain, Neck, Pain, Back, Cervical Fusion
- Trial name
- NCT04640896
- Testing
- Trigger point injection with bupivacaine, Trigger point injection with normal saline, Lidocaine skin wheal
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- George Washington University
Dry Eye Disease, Meibomian Gland Dysfunction
Preoperative iLux on Cataract Surgery Derived Dry Eye Disease Due to Meibomian Gland Dysfunction
This prospective study will investigate the effect of pre-operative Systane iLux system administration in treated cataract induced dry eye disease.
- Conditions
- Dry Eye Disease, Meibomian Gland Dysfunction, Cataract Senile, Dry Eye Syndromes
- Trial name
- NCT06483750
- Testing
- Systane iLux Treatment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- George Washington University
Quality of Life, Cancer
Evaluating Cancer Survivorship Care Models
The Evaluating Cancer Survivorship Care Models project is an innovative 3-year study that is collecting data to help understand how to best deliver follow-up care to cancer survivors.
- Trial name
- NCT02362750
- Testing
- Consultative Specialized Survivorship Clinic (CSSC), Longitudinal Specialized Survivorship Clinic (LSSC), Oncology Embedded Survivorship Clinic (OESC)
- Where
- United States
- Volunteers
- 991 people
- Sponsor
- George Washington University
Survivorship, Cancer
mHealth for Young Adult Cancer Survivors
We aim to refine and pilot test an 8-week phone- and app-based intervention to promote hope, and thereby mitigate life disruption caused by cancer diagnosis and treatment, among young adults (YAs); our proposal involves (Aim 1)…
- Conditions
- Survivorship, Cancer, Psychological Well-Being
- Trial name
- mHealthAYA (NCT05905250)
- Testing
- an empirically supported protocol, further refined with evidence-based strategies, Health education
- Where
- United States
- Volunteers
- 155 people
- Sponsor
- George Washington University
Breastfeeding
Intergenerational Transmission of Low-calorie Sweeteners Via Breast Milk
This project aims to measure the widely consumed low-calorie sweeteners (LCS) sucralose and acesulfame-potassium, in maternal breast milk and plasma at pre-specified timepoints over 72 hours and in a single sample of infants'…
- Trial name
- NCT05379270
- Testing
- Diet soda
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- George Washington University