Research institution
Turku University Hospital Clinical Trials
Studies where Turku University Hospital is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 50Tick Borne Encephalitis (TBE), Lyme Borreliosis
FINtick - a Prospective Multicenter Study on Tick-borne Infections in Finland
Ticks in Finland can carry several microbes that may infect humans. The best known tick-borne diseases are Lyme borreliosis and tick-borne encephalitis (TBE).
- Conditions
- Tick Borne Encephalitis (TBE), Lyme Borreliosis, Neoehrlichiosis, Tick-Borne Diseases
- Trial name
- FINtick (NCT07897825)
- Where
- 3 sites in Finland
- Volunteers
- 850 people
- Sponsor
- Turku University Hospital
Atheroscleroses, Inflammation
Vascular Inflammation in Atherosclerosis - Whole Body Molecular PET/CT Imaging Using Folate Receptor β
This study investigates inflammation in the blood vessels of people with coronary artery disease (CAD) or a recent myocardial infarction.
- Trial name
- ATHERO-FOL (NCT07877324)
- Testing
- 18F-AlF-NOTA-Folate PET
- Where
- Finland
- Volunteers
- 90 people
- Sponsor
- Turku University Hospital
Arthrosis
Changes in Physical Activity, Sleep and Knee Function After Same-Day Discharge Knee Arthroplasty
The goal of this observational study is to examine changes in physical activity, sleep quality, knee extension and flexion strength, knee range of motion, and patient-reported outcomes before and after same-day discharge knee…
- Trial name
- ORTOMOVE (NCT07840391)
- Testing
- Medial unicompartmental knee arthroplasty (UKA), Total knee arthroplasty (TKA)
- Where
- 2 sites in Finland
- Volunteers
- 120 people
- Sponsor
- Turku University Hospital
Healthy, Vaginal Discharge
Vaginal and Oral Microbiome Crosstalk
To study the vaginal and oral microbiome by swab samples. On selected cases, also papa smear will be studied.
- Trial name
- NCT02898818
- Testing
- vaginal and oral swab sample, questionnaire, papa smear
- Where
- Finland
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Cardiac Sarcoidosis, Infective Endocarditis
A Prospective Diagnostic Trial of Al[¹⁸F]F-NOTA-folate PET in Patients With Suspected Cardiac Sarcoidosis and Infective Endocarditis
The goal of this prospective diagnostic study is to evaluate the imaging characteristics, diagnostic performance, radiation dosimetry, and safety of Al[¹⁸F]F-NOTA-folate PET imaging in patients with suspected cardiac sarcoidosis…
- Trial name
- FOL-CARD (NCT07814222)
- Testing
- Al[¹⁸F]F-NOTA-folate PET imaging, [15O]water PET imaging, Echocardiography
- Where
- Finland
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Acute Otitis Media, Otitis Media
Parent-led Assessment and Recognition of AOM Using Digital Ear Imaging
Acute otitis media (AOM) is the most common bacterial infection in young children and a major contributor to healthcare utilization and costs.
- Trial name
- PARENT-EAR (NCT07640568)
- Testing
- Assigning of a digital otoscope to the families in the intervention group
- Where
- 2 sites in Finland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Borderline Symptoms, Borderline Personality Disorder
The Effectiveness of Group Schema Therapy in the Treatment of Borderline Symptoms in Adolescents
The goal of this randomized and controlled trial is to assess the effectiveness of group schema therapy in the treatment of adolescents with borderline symptoms.
- Trial name
- NCT06606002
- Testing
- Group schema therapy, Treatment as Usual (TAU)
- Where
- Finland
- Volunteers
- 64 people
- Sponsor
- Turku University Hospital
Sleep Apnea, Obstructives, Tonsil Hypertrophy
Randomized Clinical Trial for Tonsil Surgery in Adults With Obstructive Sleep Apnea and Enlarged Tonsils
The aim is to investigate whether the tissue-preserving tonsil surgery technique is as effective as complete tonsil removal in the treatment of obstructive sleep apnea.
- Trial name
- TONOS (NCT07580170)
- Testing
- Tonsillectomy, Tonsillotomy
- Where
- 4 sites in Finland
- Volunteers
- 132 people
- Sponsor
- Turku University Hospital
Recurrent Tonsillitis, Chronic Tonsillitis
Recovery From Tonsil Surgery.
The goal of this study is to optimize the duration of sick leave and the usage of opioids following partial tonsillar surgery in adults by comparing the recovery after extracapsular tonsillectomy (ECTE) with recovery after…
- Trial name
- FINITE-2 (NCT07598201)
- Testing
- extracapsular tonsillectomy, intracapsular tonsillectomy
- Volunteers
- 90 people
- Sponsor
- Turku University Hospital
Physical Activity During Cancer Treatment
Effective Implementation of the Physical Activity and Motor Skills Intervention for 3-6-year-old Children With Cancer (EMPOWER)
The study examines the association of digitally provided EMPOWER - exercise intervention on 3-6-year-old child's physical activity (PA), motor performance and quality of life (QoL) during and after cancer treatment.
- Trial name
- EMPOWER (NCT07488494)
- Testing
- Digital tool for physical activity guidance and follow-up, Physical activity guidance
- Volunteers
- 40 people
- Sponsor
- Turku University Hospital
Completed, with results posted
All 3Squamous Cell Carcinoma of the Head and Neck
Reproducibility of Intratumor Distribution of 18F-EF5 in Head and Neck Cancer
The results of previous studies suggest further development of [18F]EF5 as a PET tracer for imaging hypoxia. This is a non-randomized prospective study to obtain information on reproducibility of [18F]EF5 intratumor distribution…
- Trial name
- NCT01774760
- Testing
- 18F-EF5, Pretreatment PET/CT-scan (performed two times)
- Where
- Finland
- Volunteers
- 10 people
- Sponsor
- Turku University Hospital
Lymphoma, Hodgkin Disease
Molecular and Whole-body MR Imaging in Lymphomas
Lymphomas are classified as Hodgkin's or non-Hodgkin's lymphomas, of which especially the latter represent a heterogeneous group with varying patterns of prognosis, biological behaviour and response to treatment.
- Conditions
- Lymphoma, Hodgkin Disease, Lymphoma, Non-Hodgkin
- Trial name
- MILY (NCT02389101)
- Testing
- 68Ga-DOTANOC PET/CT; Diffusion weighted MRI
- Where
- Finland
- Volunteers
- 21 people
- Sponsor
- Turku University Hospital
Gestational Diabetes
Metformin Versus Insulin in Gestational Diabetes
Gestational diabetes is traditionally treated with insulin. Metformin is a peroral drug used worldwide in the treatment of type 2 diabetes and also in a few studies on patients with gestational diabetes.
- Trial name
- NCT01240785
- Testing
- metformin, insulin
- Volunteers
- 221 people
- Sponsor
- Turku University Hospital