Research institution
University Hospital, Ghent Clinical Trials
Studies where University Hospital, Ghent is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 115Parkinson Disease
Extended Reality Rehabilitation in Parkinson's Disease
This study investigates how different types of extended reality, Virtual Reality (fully immersive) and Mixed Reality (partly real-world), can be used in rehabilitation for people with Parkinson's disease.
- Trial name
- XR-PD (NCT07863102)
- Testing
- Extended reality balance training
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- University Hospital, Ghent
Physical and Psychological Evaluation of Hormonal Therapy in Transsexual Persons
A European Network for the Investigation of Gender Incongruence
The physical and psychological effects of the hormonal treatment of transsexual persons are not sufficiently described. 'Transparency' wants to answer this question in a prospective manner, in a multicenter study to describe…
- Trial name
- ENIGI (NCT01072825)
- Testing
- questionnaires, blood sampling, clinical evaluation
- Where
- 4 sites in Belgium, Italy and 2 more
- Volunteers
- 125 people
- Sponsor
- University Hospital, Ghent
Gait
Normative Database for Gait Analysis on the GRAIL UZ Gent
The aim of this study is to collect a large set of norm/control data on an instrumented treadmill (the Gait Real-time Analysis Interactive Lab - GRAIL) at the university hospital of Ghent for the purpose of clinical studies as…
- Trial name
- B670201942108 (NCT04987346)
- Testing
- Walking on an instrumented treadmill, Walking on an instrumented treadmill while dual-tasking
- Where
- Belgium
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Fetal Growth Restriction, Cardiac Remodeling, Ventricular
Speckle Tracking Echocardiography as a Tool for Early Diagnosis of Impaired Fetal Growth Twin Pregnancies
In this project there are 2 time points during the pregnancy included, namely at 21 weeks and 30 weeks of gestation, to measure the predictive values of FGR, strain and strain rate.
- Conditions
- Fetal Growth Restriction, Cardiac Remodeling, Ventricular, Placental Insufficiency, Air Pollution
- Trial name
- HEART (NCT05423665)
- Testing
- sample collection
- Where
- 3 sites in Belgium, Netherlands
- Volunteers
- 360 people
- Sponsor
- University Hospital, Ghent
Contraception
Evaluation of the Safety and Efficacy of the ReLARC Inserter During the Insertion Procedure of GYNEFIX Intrauterine Copper Bearing Contraceptive Device With a Follow-up of 3 Years.
Insertion under vision such as hysteroscopy allows the ability to visualize the uterus prior to insertion, to assess uterine compatibility and the assurance of proper device placement.
- Trial name
- ReLARC - REL-0 (NCT05702281)
- Testing
- ReLARC
- Where
- Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Anastomotic Leak Esophagus
OBSiDiAN in a Stapled Circular Esophagogastric Anastomosis After Ivor Lewis Esophagectomy
Oesophagectomy is very invasive surgery. A leakage at the level of the connection between oesophagus and stomach made during surgery causes a lot more problems and can lead to death.
- Trial name
- Obsidian ph II (NCT05713955)
- Testing
- Obsidian
- Where
- 2 sites in Belgium
- Volunteers
- 90 people
- Sponsor
- University Hospital, Ghent
Liver Transplant Failure, Prognostic Biomarkers
Serum GLYcomics to Predict Graft Loss and Mortality After Liver Transplantation
The first 12 months after liver transplantation (LT) are decisive in posttransplant outcome, as almost half of deaths and two thirds of graft loss requiring retransplant occur in the first year after LT.
- Trial name
- GLYGALT (NCT05866796)
- Testing
- GlycoTransplantTest
- Where
- Belgium
- Volunteers
- 600 people
- Sponsor
- University Hospital, Ghent
HIV-1-infection, HIV Seropositivity
Immuno-virological Evaluation of Persons Living With HIV (PLWH)
This is a dual arm (arm 1 and arm 2) multi-centric non-randomized (prospective) study. Two new multicentric cohorts will be set up in 4 Belgian HIV reference centers (UZ Gent, UZ Brussel, University Hospital Liege and St.
- Trial name
- NCT05973825
- Testing
- Leucapheresis
- Where
- Belgium
- Volunteers
- 24 people
- Sponsor
- University Hospital, Ghent
Pharmacokinetics, Amoxicillin-clavulanate
Pediatric Antibiotic Dosing in Extracorporal Membrane Oxygenation (PADECMO)
Pharmacokinetics of antibiotics in critically ill neonates, infants and children on extracorporeal membrane oxygenation (ECMO).
- Conditions
- Pharmacokinetics, Amoxicillin-clavulanate, Piperacillin-tazobactam, Meropenem
- Trial name
- PADECMO (NCT06426836)
- Testing
- Amoxicillin-clavulanate, Piperacillin-tazobactam, Meropenem
- Where
- 3 sites in Belgium
- Volunteers
- 300 people
- Sponsor
- University Hospital, Ghent
Healthy, Stroke
The Influence of Cortical Lateralization on Selective Motor Control of the Arm Swing During Independent Walking After Stroke.
The upper limbs play an essential role for safe and efficient walking in healthy persons and persons post-stroke. Nevertheless, in current post-stroke gait rehabilitation (research) the upper limbs are barely targeted.
- Trial name
- NCT06442579
- Testing
- Walking on a treadmill
- Where
- 2 sites in Belgium
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Completed, with results posted
All –Neonatal Brachial Plexus Palsy
Validation Study Of A Digital Measuring Device For Central Hand Representation In Children With A Neonatal Brachial Plexus Palsy
Hand function is one of the most complex and sophisticated sensorimotor skills, controlled by the interplay of precise motor efferent and multisensory afferent stimuli.
- Trial name
- NCT06950879
- Testing
- Measurement
- Where
- Belgium
- Volunteers
- 18 people
- Sponsor
- University Hospital, Ghent
Vestibular Disorder, Hearing Impaired Children
Vestibular Infants Screening-Flanders
Hearing-impaired children are at risk for a vestibular impairment, as the auditory and vestibular end organs are closely related.
- Trial name
- VIS-Flanders (NCT05061069)
- Testing
- cervical vestibular evoked myogenic potentials (cVEMP)
- Where
- 19 sites in Belgium
- Volunteers
- 301 people
- Sponsor
- University Hospital, Ghent
Erosive Osteoarthritis
The Use of Steovess/Binosto After Denosumab Discontinuation to Prevent Increase in Bone Turnover
It is hypothesized that effervescent alendronate will be able to maintain bone turnover markers within the pre-menopausal reference range and thereby reducing the likelihood of bone turnover associated changes (rebound effect)…
- Trial name
- NCT04403698
- Testing
- Alendronate Effervescent Oral Tablet
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Hospital, Ghent
Voice Disorders in Children, Vocal Nodules in Children
Effect of Semi-occluded Vocal Tract Therapy on the Phonation of Children With Vocal Fold Nodules
The goal of this clinical trial is to determine and compare the effects of different voice therapy programs in children with vocal fold nodules.
- Conditions
- Voice Disorders in Children, Vocal Nodules in Children, Hoarseness, Dysphonia
- Trial name
- NCT05878197
- Testing
- Straw phonation, Resonant voice therapy, Vocal Hygiene
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Hospital, Ghent
Hand Osteoarthritis
RANKL-blockade for the Treatment of Erosive Osteoarthritis (OA) of Interphalangeal Finger Joints
This is a randomized, double blind placebo controlled one-site proof-of-concept study in subjects with erosive osteoarthritis (OA) of interphalangeal (IP) finger joints.
- Trial name
- NCT02771860
- Testing
- denosumab, Calcium/Vit D supplementation
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent